[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"biliary-and-pancreatic-diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:biliary-and-pancreatic-diseases":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100053368","effect-of-patient-anxiety-level-prior-to-undergoing-ercp-and-procedure-tolerability-and-outcomes-100053368",false,"NCT07699731","Effect of Patient Anxiety Level Prior to Undergoing ERCP and Procedure Tolerability and Outcomes.","The Effect of Pre-procedural Anxiety Level on Procedure Tolerability and Quality of ERCP in Consciously Sedated Patients","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Undergoing ERCP for any indication with conscious sedation\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Inability or refusal to provide informed consent\n* Cognitive impairment or language barriers precluding questionnaire completion\n* Emergent ERCP where pre-procedural questionnaire administration is not feasible","ALL","18 Years",{"count":19,"type":20},200,"ESTIMATED","OBSERVATIONAL","Endoscopic Retrograde Cholangiopancreatography (ERCP) is a specialized procedure combining upper GI endoscopy and x-rays to treat hepatopancreaticobiliary diseases. Patient experiences after ERCP has been relatively understudied.\n\nThe goal of this prospective observational study is to understand how anxiety before ERCP affects patient experience and tolerance of the procedure.\n\nThis study includes adults (18 years and older) undergoing ERCP with conscious sedation at Kingston Health Sciences Centre. Researchers will measure pre-procedure anxiety and examine how it relates to patient comfort, cooperation during the procedure, and overall patient-reported experience.\n\nThe main questions are whether higher pre-procedure anxiety is associated with lower procedure tolerability and reduced cooperation during ERCP.\n\nParticipants will:\n\n1. Complete a short anxiety questionnaire before the procedure\n2. Undergo ERCP with standard sedation as planned by their care team\n3. Complete a post-procedure questionnaire about comfort, pain, and other symptoms\n4. Have procedure details and outcomes recorded from medical records\n\nEndoscopists will also complete a short survey to state any concerns prior to procedure as well as evaluate patient's cooperation during the procedure.\n\nPatient-reported experience will be compared with physician assessments of cooperation during the procedure.\n\nFindings may help recognize patients at higher risk of distress during ERCP and guide strategies to improve comfort, sedation planning, and overall procedure quality to lead to the best outcomes.",[24,25,26],"Anxiety","Biliary and Pancreatic Diseases","ERCP",[26,28,29,30,31,32,33,34,35],"Endoscopic retrograde cholangiopancreatography","Conscious sedation","Pre-procedural anxiety","Patient experience","STAI-Y","PRO-STEP","Upper endoscopy","Procedural sedation","NOT_YET_RECRUITING","2026-07-09",{"date":39,"type":40},"2026-07-13","ACTUAL",{"date":42,"type":20},"2026-08-01",{"date":44,"type":20},"2027-10-01",{"name":46,"class":47},"Mandip Rai","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100637179","a-22-factorial-randomized-controlled-trial-for-ercp-100637179","NCT07584902","A 2×2 Factorial Randomized Controlled Trial for ERCP","Effects of Propofol Versus Ciprofol and Sufentanil Versus Es-ketamine on Intraoperative Desaturation and Hypotension in Elderly Patients Undergoing ERCP: A 2×2 Factorial Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 60 years old.\n* ASA II-III level.\n* BMI\\\u003C30kg\u002Fm2.\n* Patients who require elective therapeutic ERCP.\n* Voluntarily participate in this study and sign an informed consent form. If the subject is unable to read and sign the informed consent form due to reasons such as lack of capacity, their guardian needs to act as a proxy for the informed process and sign the informed consent form. If the subject lacks the ability to read the informed consent form (such as illiterate subjects), a witness is required to witness the informed process and sign the informed consent form.\n\nExclusion Criteria:\n\n* Previous anatomical changes in the gastrointestinal tract, delayed gastric emptying, and gastric outlet obstruction.\n* Coagulation dysfunction or tendency towards nosebleeds.\n* Combined severe heart disease (coronary heart disease, myocardial infarction, congestive heart failure, left ventricular ejection fraction\\\u003C40%, tachyarrhythmia)\n* Have a history of allergies to relevant anesthetic drugs in the past.\n* Severe pulmonary diseases (severe asthma attacks, respiratory failure, severe chronic obstructive pulmonary disease, severe interstitial lung disease, large pleural effusion, severe pulmonary arterial hypertension, etc.).\n* Existing upper respiratory tract infection (within one week).\n* Uncontrolled severe hypertension.\n* Patients with increased intracranial pressure; Cerebral hemorrhage, intracranial space occupying lesions, acute phase of traumatic brain injury.\n* Glaucoma and significant increase in intraocular pressure.\n* Untreated or inadequately treated patients with hyperthyroidism.\n* Serious liver and kidney diseases.\n* Known neurological and psychiatric disorders (Parkinson's disease, epilepsy, or schizophrenia).\n* Difficult airway: The anesthesiologist assessed the presence of difficult airway before surgery.\n* Vulnerable groups other than the elderly\u002Filliterate, including those with mental illness, cognitive impairment, critically ill patients, pregnant women, etc.","60 Years",{"count":58,"type":20},236,"INTERVENTIONAL",[61],"NA","To investigate the effects of propofol vs. cyclopropofol and sufentanil vs. esketamine on intraoperative hypoxemia and hypotension in elderly patients undergoing ERCP, as well as the interaction between these two factors.",[25,64],"Endoscopic Retrograde Cholangiopancreatography (ERCP)","2026-05-07",{"date":67,"type":40},"2026-05-13",{"date":69,"type":20},"2026-04-27",{"date":71,"type":20},"2026-10-31",{"name":73,"class":47},"Gang Chen",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":59,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":48},"100594272","effect-of-deep-analgosedation-vs-endotracheal-intubation-general-anesthesia-on-on-perioperative-sedation-related-adverse-events-in-elderly-ercp-patients-100594272","NCT07017283","Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on on Perioperative Sedation Related Adverse Events in Elderly ERCP Patients","Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on Perioperative Respiratory Adverse Events in Elderly ERCP Patients: An Open-Label Randomized Controlled Trial","Inclusion criteria：\n\n1. Aged 60 and above;\n2. ASA physical status≤III;\n3. Patients who scheduled for elective therapeutic ERCP (ERCP complexity grading system;\n4. Willing to provide informed consent (or by legal guardian\u002Fwitness if applicable).\n\nExclusion criteria：\n\n1: Altered gastrointestinal anatomy, delayed gastric emptying, or gastric outlet obstruction； 2.Coagulopathy or epistaxis tendency; 3.Cardiac diseases (e.g., coronary artery disease, heart failure, arrhythmias); 4.Pulmonary diseases (e.g., asthma, COPD); 5.Prior hypersensitivity to anesthetic agents; 6.Active upper respiratory infection； 7.Severe liver and kidney diseases； 8.Difficult airway: Preoperative anesthesiologist assessment of difficult airway； 9.Psychiatric disorders, cognitive impairment, critical illness, or pregnancy.",{"count":82,"type":20},170,[61],"This study aims to investigate the impact of deep analgosedation versus endotracheal intubation general anesthesia on perioperative sedation related adverse events in elderly ERCP patients.",[25,64],"RECRUITING","2025-12-10",{"date":89,"type":40},"2025-12-18",{"date":91,"type":40},"2025-11-10",{"date":93,"type":20},"2026-02-28",{"name":73,"class":47}]