[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"biliopancreatic-diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:biliopancreatic-diseases":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100625094","endoscopic-management-of-biliopancreatic-disease-in-the-lombardy-pancreas-units-100625094",false,"NCT07418164","Endoscopic Management of Biliopancreatic Disease in the Lombardy Pancreas Units","Endoscopic Management of Suspected Biliopancreatic Disease Within the Lombardy Pancreas Units: a Prospective Observational Study","GENTLENESS","Inclusion Criteria:\n\n* Adults (≥18 years)\n* Clinical, biochemical, and\u002For imaging suspicion of pancreatic neoplasia (adenocarcinoma, neuroendocrine tumors, cystic neoplasms requiring endoscopic, surgical, or oncological treatment) or periampullary neoplasia (distal bile duct, ampulla, duodenum)\n* Candidate for EUS according to standard clinical practice\n* Ability to understand and sign informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Pregnancy or breastfeeding\n* Conditions other than those defined in the inclusion criteria\n* Inability to provide informed consent\n* Refusal to participate in the study","ALL","18 Years",{"count":20,"type":21},2500,"ESTIMATED","OBSERVATIONAL","The GENTLENESS study is a prospective, multicenter, observational registry designed to evaluate the endoscopic management of patients with suspected biliopancreatic and periampullary neoplastic diseases within the Pancreas Units network of the Lombardy Region.\n\nPatients undergoing endoscopic ultrasound (EUS) for suspected pancreatic or periampullary malignancies, including pancreatic ductal adenocarcinoma, pancreatic neuroendocrine tumors, cystic pancreatic neoplasms requiring endoscopic, surgical, or oncological management, and periampullary tumors of the distal bile duct, ampulla, or duodenum, will be prospectively enrolled according to standard clinical practice.\n\nThe study aims to assess the diagnostic accuracy of EUS-guided tissue acquisition, procedural safety, the need for repeat sampling, and organizational performance indicators, including time to definitive cyto-histological diagnosis and time to initiation of disease-specific treatment. No additional procedures beyond routine clinical care will be performed as a result of study participation.",[25,26,27],"Pancreatic Cancer","Biliopancreatic Diseases","Periampullary Neoplasms","NOT_YET_RECRUITING","2026-02-10",{"date":31,"type":32},"2026-02-18","ACTUAL",{"date":34,"type":21},"2026-04",{"date":36,"type":21},"2027-07",{"name":38,"class":39},"IRCCS San Raffaele","OTHER",13]