[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"binaural-beats\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:binaural-beats":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,77,109],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100640397","binaural-sound-during-phacoemulsification-and-posterior-chamber-lens-implantation-in-geriatric-patients-100640397",false,"NCT07609186","Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation in Geriatric Patients","Effect of Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation on Postoperative Patient Satisfaction in Geriatric Patients: a Single-blind, Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients scheduled to undergo their first phacoemulsification and posterior chamber intraocular lens implantation (PE \\& PCL) under monitored anesthesia care (MAC).\n* Patients aged 65 years or older.\n* Patients who fully understand the study and voluntarily provide written informed consent to participate.\n\nExclusion Criteria:\n\n* Patients undergoing their second consecutive PE \\& PCL surgery.\n* Patients with hearing loss, hearing impairment, or those who use hearing aids.\n* Patients unable to wear earphones due to diseases of the external auditory canal.\n* Patients who chronically use hypnotics or sedatives.\n* Patients with a history of obstructive sleep apnea or a Body Mass Index of 35 kg\u002Fm² or higher.\n* Patients with a history of alcohol or drug dependence.\n* Patients with a history of epilepsy or seizure disorders.\n* Patients who are unable to complete a written questionnaire.\n* Patients deemed unsuitable for participation in the clinical trial based on the investigator's clinical judgment.","ALL","65 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to evaluate the effects of binaural beats on patient satisfaction and intraoperative comfort in patients aged 65 years or older undergoing cataract surgery (phacoemulsification and posterior chamber intraocular lens implantation) under monitored anesthesia care (MAC) with propofol.\n\nParticipants are randomly assigned to either a binaural beat group or a control group. The binaural beat group will wear earphones and listen to binaural beats from the time they arrive at the operating room until the surgery is completed. The control group will wear identical earphones but will not receive any auditory stimulus.\n\nDuring the procedure, standard vital signs and the bispectral index (BIS) will be continuously monitored in both groups. Following the surgery, the investigators will assess the patients' overall satisfaction using a 7-point Likert scale. Secondary assessments include patient preference for the anesthesia method, intraoperative pain intensity, sedation level, anxiety level, and quality of life (EQ-VAS) measured by a visual analogue scale. Any surgery-related discomfort or adverse events will also be recorded and compared between the two groups.",[26,27,28],"Cataract","Binaural Beats","Geriatric Anesthesia","RECRUITING","2026-05-19",{"date":32,"type":33},"2026-05-27","ACTUAL",{"date":35,"type":33},"2025-08-07",{"date":37,"type":20},"2026-07-08",{"name":39,"class":40},"Seoul National University Hospital","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":64,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":41},"100626579","binaural-beats-for-postoperative-pain-and-anxiety-reduction-100626579","NCT07437469","Binaural Beats for Postoperative Pain and Anxiety Reduction","Binaural Beats vs Music of Choice for Early Postoperative Pain After Ambulatory Total Knee and Total Hip Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* American Society of Anesthesiologists Physical Status Classification System (ASA) 1-3\n* Spinal anesthesia\n* Patients receiving nerve-block in Post-Anesthesia Care Unit (PACU)\n* Primary total hip or total knee arthroplasty\n\nExclusion Criteria:\n\n* Moderate-severe hearing impairment or use of hearing aids\n* History of significant tinnitus, active delirium, chronic high-dose opioid therapy (\\>60 MME\u002Fday baseline)\n* Major psychiatric pathology\n* General anesthesia","18 Years","99 Years",{"count":52,"type":20},50,[23],"To deliver a 30-minute binaural beats audio intervention in PACU and collect pain and anxiety outcomes immediately following surgery, and 4 hours following surgery completion in adults undergoing ambulatory total knee arthroplasty and total hip arthroplasty (TKA and THA).",[56,57,58,27,59,60,61,62,63],"TKA","THA","Anxiety","Music Exposure","Total Hip Arthroplasty (THA)","Total Knee Arthroplasty","Total Knee Replacement","Total Hip Replacement",[57,56,65,66,58,67,27,59],"Total hip arthroplasty","Total knee arthroplasty","Pain","2026-04-29",{"date":70,"type":33},"2026-04-30",{"date":72,"type":33},"2026-03-09",{"date":74,"type":20},"2026-08-30",{"name":76,"class":40},"University of Miami",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":21,"phases":88,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":41},"100622706","decreasing-stress-via-virtual-reality-and-binaural-beats-in-non-clinical-adults-100622706","NCT07387107","Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults","Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults: A Randomized Controlled Study.","DESTUD","Inclusion Criteria:\n\n1\\. Adults aged 18 years or older 2. Ability to understand study procedures and provide written informed consent 3. Sufficient proficiency in the German language to complete questionnaires and follow study instructions 4. Willingness to participate in a single approximately 60-minute study session\n\nExclusion Criteria:\n\n1\\. Current or history of neurological or psychiatric disorders that may interfere with data collection (e.g., dementia, major depressive disorder, stroke, epilepsy) 2. Severe visual or hearing impairments that would limit the use of virtual reality equipment or headphones 3. History of adverse reactions to virtual reality",true,{"count":87,"type":20},52,[23],"This study is a non-clinical substudy conducted within the DESTRESS research program (NCT05036538), which investigates the effects of relaxation interventions on physiological and psychological parameters. While the main DESTRESS trial focuses on cardiac surgical patients, this additional study arm examines the same interventions in a non-clinical adult population under controlled conditions, independent of disease-, surgery-, or medication-related influences.\n\nParticipants are randomly assigned to one of several experimental conditions and take part in a single approximately 30-minute session. Depending on group allocation, the session may include exposure to natural soundscapes, natural soundscapes combined with binaural beats, virtual reality-based natural environments, virtual reality combined with binaural beats, or a control condition without a relaxation intervention.\n\nThe primary aim of the DESTUD-Study is to assess the feasibility and potential stress-reducing effects of these non-pharmacological relaxation approaches in a non-clinical setting and to support the interpretation of findings from the clinical DESTRESS trial. Physiological responses, including heart rate variability and electrodermal activity, as well as self-reported stress measures, are collected before, during and after the conditions.",[91,92,93,27],"Stress","Relaxation","Virtual Reality",[93,27,95,96,97,98,99],"Heart Rate Variability","Stress Reduction","Relaxation Intervention","Non-Clinical Population","Electrodermal Activity","2026-03-11",{"date":102,"type":33},"2026-03-13",{"date":104,"type":33},"2026-03-05",{"date":106,"type":20},"2026-07-15",{"name":108,"class":40},"Heart and Brain Research Group, Germany",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":85,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":21,"phases":119,"briefSummary":120,"conditions":121,"keywords":122,"overallStatus":123,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":128,"leadSponsor":130,"locationsCount":4},"100626152","effects-of-nature-based-virtual-reality-and-binaural-beats-on-heart-rate-variability-and-relaxation-100626152","NCT07431918","Effects of Nature-Based Virtual Reality and Binaural Beats on Heart Rate Variability and Relaxation","Effects of Nature-Based Virtual Reality and Binaural Beats on Heart Rate Variability and Relaxation: A Controlled Within-Subject Study","VRELAX","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Ability to understand study procedures and provide written informed consent\n* Sufficient proficiency in the German language to complete questionnaires and follow study instructions\n* Willingness to participate in a single approximately 60-minute study session\n\nExclusion Criteria:\n\n* Current or history of neurological or psychiatric disorders that may interfere with data collection (e.g., dementia, major depressive disorder, stroke, epilepsy)\n* Severe visual or hearing impairments that would limit the use of virtual reality equipment or headphones\n* History of adverse reactions to virtual reality",{"count":118,"type":20},18,[23],"The VRELAX study is a non-clinical sub-study within the \"Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients\"- research program (DESTRESS; NCT05036538), which investigates non-pharmacological relaxation interventions using virtual reality and binaural auditory stimulation. In a randomized counterbalanced within-subject design, non-clinical adult participants complete two sessions separated by a 1 day intervention-free interval. A 30-minute immersive nature-based virtual reality exposure combined with gradually decreasing binaural beats (10-1 Hertz (Hz)), and a control condition without relaxation. Heart rate variability (HRV) is recorded continuously, and subjective stress is assessed before and after each condition. The primary outcome is parasympathetic activation operationalized as high-frequency (HF) power of heart rate variability. Secondary outcomes include additional HRV parameters and self-reported stress ratings. The study aims to characterize short-term relaxation effects and evaluate the feasibility of independent use in everyday settings, supporting interpretation of clinical findings of the DESTRESS trial.",[91,92,93,27],[93,27,95,96,97,98],"NOT_YET_RECRUITING","2026-02-18",{"date":126,"type":33},"2026-02-25",{"date":126,"type":20},{"date":129,"type":20},"2026-12-20",{"name":108,"class":40}]