[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bis":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100634172","deep-learning-framework-for-continuous-depth-of-anesthesia-forecasting-100634172",false,"NCT07536230","Deep Learning Framework for Continuous Depth of Anesthesia Forecasting","Validation of a Deep Learning Framework for Continuous Forecasting of Pharmacodynamic Responses and Physiological Trajectories During General Anesthesia","Inclusion Criteria:\n\n* Patients scheduled for elective surgery requiring general anesthesia.\n* Procedures requiring continuous depth of anesthesia monitoring (BIS).\n\nExclusion Criteria:\n\n\\- Procedures where the primary anesthetic plan does not involve continuous electronic data capture.",true,"ALL",{"count":19,"type":20},115,"ESTIMATED","1 Day","OBSERVATIONAL","The integration of Artificial Intelligence (AI) in anesthesiology offers the potential to shift patient monitoring from reactive to predictive. Deep learning architectures, specifically Long Short-Term Memory (LSTM) networks, excel at processing complex, time-series data to forecast future clinical states.\n\nWhile standard PK\u002FPD models (such as the state of the art Eleveld model for Propofol and Remifentanil) estimate target-site drug concentrations (Ce), they do not account for real-time, patient-specific dynamic responses. This study aims to deploy an AI framework designed to predict future physiological states.",[25,26,27,28,29,30,31,32],"BIS","BIS-EEG","Artifical Intelligence","Intraoperative","Machine Learning","Anesthesia","Anesthesia Awareness","Predictive Model","NOT_YET_RECRUITING","2026-04-10",{"date":36,"type":37},"2026-04-17","ACTUAL",{"date":39,"type":20},"2026-06-01",{"date":41,"type":20},"2026-09-01",{"name":43,"class":44},"Universitair Ziekenhuis Brussel","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100562694","comparison-of-the-effect-of-testosterone-administered-for-micropenis-hypospadias-surgery-with-bispectral-index-100562694","NCT06606496","Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index","Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index and Other Parameters in General Anesthesia: A Prospective Observational Study","Inclusion Criteria:\n\n* Ages 1-16\n* Patients with ASA I (Normal healthy patients except for surgery)\n* Patients who will undergo surgery for hypospadias repair\n\nExclusion Criteria:\n\n* Morbidly obese patients (body mass index \\> 40kg\u002Fm2)\n* ASA II-III-IV patients (other groups of patients with additional diseases)\n* Volunteers who do not want to participate in the study","MALE","1 Year","16 Years",{"count":57,"type":20},22,"The aim of this observational study is to learn the effects of hormone therapy (testosterone) applied in micropenis hypospadias surgery on the depth of anesthesia under general anesthesia. The main question it aims to answer is: The effect of testosterone therapy on the depth of general anesthesia. Based on these, to comment on the depth of anesthesia of patients who have just started using testosterone for sex change. To follow the depth of anesthesia of patients who have undergone hypospadias surgery with BIS monitoring and to record respiratory parameters under general anesthesia.",[60,61,25],"General Anesthesia","Testosterone","2024-09-18",{"date":64,"type":37},"2024-09-23",{"date":66,"type":20},"2024-09",{"date":68,"type":20},"2024-12",{"name":70,"class":44},"Namik Kemal University",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":16,"sex":17,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":4},"100553784","use-of-sevoflurane-to-test-concept-of-cognitive-reserve-100553784","NCT06490588","Use of Sevoflurane to Test Concept of Cognitive Reserve","The Use of Sevoflurane to Test the Concept of Intra-individual Variability in Bispectral Index Monitor and Cognitive Reserve by Examining Time to Emergence and Recovery","Inclusion Criteria:\n\n* \\- Minimal completion of high-school education\n* Adult patient \\\u003C 85 years of age\n* No prior known history of cognitive\u002Fbrain disease\n* ASA class I-II\n* Undergoing general anesthesia with sevoflurane for maintenance anesthesia\n* Same-day surgery\n* Elective procedures\n* No prior history of cardiac disease\n\nExclusion Criteria:\n\n* \\- History of chronic pain\n* Perioperative use of anesthetic agents other than propofol, fentanyl, dilaudid, and sevoflurane\n* History of alcohol\u002Fsubstance druge abuse\n* Psychiatric history\n* Morbid history\n* History of OSA, stroke, or TIA\n* Blindness\n* Deafness","18 Years","90 Years",{"count":81,"type":20},70,"Previous pilot study had demonstrated a correlation between cognitive reserve and BIS variability during steady state of anesthesia. This study, we intend to evaluate the association between BIS variability and emergence and recovery time from anesthesia.",[84,25],"Cognitive Reserve","2024-06-28",{"date":87,"type":37},"2024-07-08",{"date":66,"type":20},{"date":90,"type":20},"2026-09",{"name":92,"class":44},"Los Angeles General Medical Center"]