[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"block-heart\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:block-heart":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100563787","left-bundle-branch-area-pacing-or-biventricular-pacing-in-af-and-left-ventricular-dysfunction-100563787",false,"NCT06620705","Left Bundle Branch Area Pacing or Biventricular Pacing in AF and Left Ventricular Dysfunction","Pacing Away from Heart Failure: Left Bundle Branch Area Pacing or Biventricular Pacing in Patients with Atrial Fibrillation and Left Ventricular Dysfunction","INCLUSION CRITERIA\n\nIn order to be eligible to participate in this study, a subject must meet all of the following criteria:\n\n* Adults ≥18 years with permanent AF and LVEF \\< 50% who either require ventricular pacing because of bradycardia including patients undergoing AV junction ablation, or have an indication for cardiac resynchronization therapy.\n* Expected percentage of ventricular pacing \\> 40%\n* ≥ 3 months of heart failure medication optimization\n\nOf note, patients who already have a device, but require an upgrade to a CRT device, can also be included\n\nEXCLUSION CRITERIA\n\nA potential subject who meets any of the following criteria will be excluded from participation in this study:\n\n* Age \\< 18 years\n* Pregnancy or active pregnancy wish\n* Not eligible for implantation of an RV lead, LBBAP lead, or LV lead in the coronary sinus\n* Recent valve intervention\u002Fsurgery or acute myocardial infarction (\\< 6 months)\n* NYHA functional class IV heart failure, left ventricular assist device or cardiac transplant","ALL","18 Years",{"count":19,"type":20},34,"ESTIMATED","INTERVENTIONAL",[23],"NA","It is unknown whether left bundle branch area pacing (LBBAP) or biventricular pacing best prevents or reverses left ventricular (LV) adverse remodelling in patients with atrial fibrillation (AF) who require ventricular pacing or CRT. This randomized non-inferiority cross-over trial will compare left ventricular end-systolic volume change and secondary endpoints between LBBAP and biventricular pacing in patients with AF and LV dysfunction.",[26,27,28],"Heart Failure","Block, Heart","Pacing-Induced Cardiomyopathy",[30,31,32,33,34,35],"pacing","cardiac resynchronization therapy","left bundle branch area pacing","conduction system pacing","heart failure","heart block","RECRUITING","2024-09-26",{"date":39,"type":40},"2024-10-01","ACTUAL",{"date":42,"type":40},"2024-09-10",{"date":44,"type":20},"2028-10",{"name":46,"class":47},"srdpiers","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":85,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":106},"100541040","contemporary-cardiac-stimulation-in-clinical-practice-left-biventricular-right-and-conduction-system-pacing-100541040","NCT06324682","ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","Evaluation of conTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","TREEBEARD","Inclusion Criteria:\n\n* Indication for cardiac stimulation\n* Having performed the implantation of a device for cardiac stimulation\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years;\n* Pregnancy status;",{"count":57,"type":20},8400,"OBSERVATIONAL","The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical practice of the participating centres. The contribution of non-fluoroscopic anatomical and electrophysiological reconstruction systems to device implantation procedures will also be evaluated.\n\nParticipants \\[patients over 18 years old with an indication to receive a definitive pacemaker\u002Fintracardiac defibrillator implant\\] will receive a permanent cardiac pacing implant as requested according to European Society of Cardiology (ESC) guidelines; the investigators will evaluate procedural efficacy and safety of different implantation approaches.",[61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,27,81,82,83,84],"Arrhythmias, Cardiac","Atrioventricular Block","Reduced Systolic Function","Atrial Fibrillation","Bradyarrhythmia","Ventricular Tachycardia","Ventricular Dysfunction","Ventricular Fibrillation","Ventricular Arrythmia","Atrioventricular Nodal Disease","Atrioventricular Conduction Defects","Atrioventricular Block Complete","Atrioventricular Block Incomplete","Atrioventricular Junctional Rhythm","Bundle-Branch Block","Left Bundle-Branch Block","Heart Failure, Systolic","Block;Atrioventricular","Block; Arrhythmic","Block; Mobitz","Block, Fascicular","Block Branch Bundle Left","Heart Failure，Congestive","Heart Arrhythmia",[86,87,62,65,67,88,89,90,91,92,93,94,95,72,96,69,68,66],"Pace maker (PM)","Implantable cardioverter defibrillator (ICD)","Cardiac Resynchronization therapy","Conduction System Pacing","His Pacing","Left bundle branch area pacing (LBBAP)","CRT","CSP","Primary prevention","Secondary prevention","Heart failure","2024-03-19",{"date":99,"type":40},"2024-03-22",{"date":101,"type":40},"2023-01-01",{"date":103,"type":20},"2034-12-31",{"name":105,"class":47},"University Hospital of Ferrara",31]