[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"blood-donation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:blood-donation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100635875","donor-lifestyle-and-nutritional-status-blood-component-quality-and-patient-safety-esencia-100635875",false,"NCT07558369","Donor Lifestyle and Nutritional Status, Blood Component Quality, and Patient Safety (ESENCIA)","Lifestyle of Blood Donors and Its Impact on the Quality of Blood Components During Storage and Patient Safety","ESENCIA","Inclusion Criteria:\n\n* Eligible candidates according to Mexican regulatory standards for blood donation (NOM-253-SSA1-2012)\n\nExclusion Criteria:\n\n\\- Refusal to provide specific informed consent for participation in the research",true,"ALL","18 Years","64 Years",{"count":22,"type":23},1014,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate how blood donors' lifestyle and nutritional status influence the quality of packed red blood cells (pRBCs) during storage and their impact on patient safety in transfused neonates and postpartum women. The main questions it aims to answer are:\n\n1. Are donor lifestyle and nutritional profiles associated with the development of storage lesions in pRBCs?\n2. Do these donor-related factors influence clinical outcomes after transfusion in neonates and postpartum women?\n3. Are storage lesion in pRBCs associated with clinical outcomes in transfused neonates and postpartum women?\n\nResearchers will compare pRBC units stratified according to donor lifestyle and nutritional profiles to determine differences in storage lesion biomarkers and post-transfusion clinical outcomes.",[27,28],"Blood Donation","Blood Transfusion",[28,30],"Storage Lesions","NOT_YET_RECRUITING","2026-04-23",{"date":34,"type":35},"2026-04-30","ACTUAL",{"date":37,"type":23},"2026-07",{"date":39,"type":23},"2029-07",{"name":41,"class":42},"Instituto Nacional de Perinatologia","OTHER_GOV",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":43},"100600116","docudrama-for-blood-donation-in-ghana-ddid-100600116","NCT07093307","Docudrama for Blood Donation in Ghana (DDID)","Using a Docudrama Intervention to Increase Repeat Donation Among First-time Blood Donors in Ghana: a Pilot Cluster Randomized, Pragmatic Type 1 Effectiveness- Implementation Hybrid Trial","DDID","Inclusion Criteria:\n\n* At least 18 years-old\n* First-time whole blood donor with the SZBC of the NBSG\n* Eligible to donate again at the time of eligibility confirmation\n* Consent to participate\n* Has a valid contact phone number or access to a valid contact phone number\n* Understands one of English, Twi, or Ga\n* Be willing to watch a docudrama on blood donation\n\nExclusion Criteria:\n\n* History of more than one lifetime whole blood donation (with any blood center)",{"count":53,"type":23},180,"INTERVENTIONAL",[56],"NA","A cluster pilot RCT to evaluate the effectiveness of the docudrama compared to a control group (usual engagement with blood services) on repeat blood donation attempts among first-time blood donors. Secondary outcomes will be blood donor retention, attitudes, subjective norms, perceived behavioral control and intention as potential mediators of blood donation behavior among first-time blood donors. The cluster pilot RCT will have two arms: 1) docudrama and 2) control. Randomization will stratify by the type of site: mobile versus fixed. Each participant in the docudrama arm will receive the intervention one time immediately after blood donation. Participants in both the docudrama arm and control arm will receive standard blood donor communications and will be followed for six months. Actualized blood donation is possible every four months using NBSG guidelines; however, blood donation sessions may not occur at the blood donation sites until six months. Return blood donation attempts will be evaluated using the Southern Zonal Blood Center (SZBC) records (primary outcome) and participant self-report (secondary outcome) at six months. Secondary measures will be evaluated at baseline and six months from enrollment. The duration of the study will be 11 months, allowing for five months to achieve enrollment goals and six months of follow-up for the last individual enrolled.",[27],[60],"Docudrama","RECRUITING","2025-09-22",{"date":64,"type":35},"2025-09-23",{"date":66,"type":35},"2025-08-11",{"date":68,"type":23},"2026-08",{"name":70,"class":71},"University of Minnesota","OTHER",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":54,"phases":83,"briefSummary":84,"conditions":85,"keywords":90,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":43},"100578262","group-o-whole-blood--storage-lesion-impact-and-inflammation-100578262","NCT06809010","grouP O wholE blooD : storagE leSion impacT And infLammation","grouP O wholE blooD (LTO-WB): storagE leSion impacT And infLammation","PEDESTAL EFS","Inclusion Criteria:\n\nSelf-referred donors eligible for blood donation (whole blood and\u002For platelet\u002Fplasma apheresis), meeting the following inclusion criteria:\n\n* Be in good health\n* Weigh at least 50 kg\n* Must be between 18 and 70 years of age for whole blood donation and between 18 and 65 years of age for plasma\u002Fplatelet donation by apheresis.\n\nExclusion Criteria:\n\nSubjects ineligible to donate blood","65 Years",{"count":82,"type":23},30,[56],"\"Etablissement Français du Sang\" (EFS) prepares labile blood products from blood donations that are separated by type (red blood cells, plasma and platelets).\n\nThe \"Centre de Transfusion Sanguine des Armées\" (CTSA) produces an innovative labile blood product, LTO-WB, corresponding to group O leukocyte-free whole blood.\n\nThe objective of the PEDESTAL EFS study is to compare the inflammatory and biological characteristics of blood products prepared by the EFS vs. the labile blood product prepared by the CTSA.",[27,86,87,88,89],"Blood Platelets","Blood Donors","Inflammation","Transfusion",[91,92,93,94,95,96,97,98,99,100],"blood","LTO-WB","characterization of labile blood products","whole blood","apheresis","plasma","platelet","red blood cells","inflammation","transfusion","2025-08-04",{"date":103,"type":35},"2025-08-06",{"date":105,"type":35},"2025-03-12",{"date":107,"type":23},"2028-02",{"name":109,"class":71},"Etablissement Français du Sang"]