[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"body-composition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:body-composition":30},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,41,0,25,[9,54,80,106,133,164,195,228,252,276,320,347,376,406,449,480,507,533,557,586,608,626,642,658,690],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100643401","body-roundness-index-and-mortality-in-icu-patients-100643401",false,"NCT07631429","Body Roundness Index and Mortality in ICU Patients","Body Roundness Index as a Predictor of Mortality in Adult Intensive Care Unit Patients: A Prospective Multicenter Cohort Study (BRI-ICU)","BRI-ICU","Inclusion Criteria:\n\n* Age ≥18 years\n* ICU admission with expected stay ≥24 hours\n* Waist circumference and height measurable within 24 hours of admission\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* ICU stay \\\u003C24 hours\n* Missing or unmeasurable anthropometric data (e.g., severe edema, abdominal wound, morbid obesity precluding measurement)\n* Pregnancy\n* Readmission (only first ICU admission included)","ALL","18 Years",{"count":21,"type":22},550,"ESTIMATED","28 Days","OBSERVATIONAL","This study investigates whether Body Roundness Index (BRI), an anthropometric measure derived from waist circumference and height, can predict mortality in adult intensive care unit (ICU) patients. BRI captures central adiposity and body fat distribution more accurately than Body Mass Index (BMI). In this prospective multicenter cohort study, BRI will be measured at ICU admission and its association with ICU mortality, 28-day mortality, hospital mortality, mechanical ventilation duration, ICU length of stay, and acute kidney injury will be evaluated. The predictive performance of BRI will also be compared with BMI.",[27,28,29,30],"Critical Illness","Obesity & Overweight","Mortality in Intensive Care Units","Body Composition",[32,33,34,35,36,37,38,39,40],"Body Roundness Index","BRI","ICU mortality","Critical illness","Anthropometric measures","Central adiposity","BMI","Obesity paradox","Waist circumference","NOT_YET_RECRUITING","2026-06-05",{"date":44,"type":45},"2026-06-08","ACTUAL",{"date":47,"type":22},"2026-08-01",{"date":49,"type":22},"2027-12-01",{"name":51,"class":52},"Ondokuz Mayıs University","OTHER",1,{"id":55,"slug":56,"hasResults":12,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":53},"100640124","effects-of-blood-flow-restriction-training-on-body-composition-and-maximal-strength-in-military-personnel-100640124","NCT07628478","Effects of Blood Flow Restriction Training on Body Composition and Maximal Strength in Military Personnel","Effects of Blood Flow Restriction Training on Body Composition and Maximal Strength in Military Personnel: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Male cadets from military academy;\n* No contraindications to blood flow restriction training (no circulatory diseases, skin allergies);\n* Healthy and capable of high-intensity exercise;\n* Signed informed consent\n\nExclusion Criteria:\n\n* Major sports injury within 2 years (fracture, ligament tear, muscle\u002Ftendon rupture, habitual joint dislocation);\n* Cardiovascular or visceral organ diseases;\n* Other conditions unsuitable for training",true,{"count":63,"type":22},36,"INTERVENTIONAL",[66],"NA","This study aims to compare the effects of low-intensity blood flow restriction training combined with resistance training versus traditional high-intensity resistance training on body composition (skeletal muscle mass, body fat mass) and maximal strength (isometric mid-thigh pull, vertical jump, isometric squat pull) in male military academy cadets. The study lasts for 6 weeks and adopts a randomized parallel-group design.",[69,70,30],"Physical Fitness","Muscle Strength","RECRUITING","2026-06-04",{"date":42,"type":45},{"date":75,"type":22},"2026-06-01",{"date":77,"type":22},"2026-07-28",{"name":79,"class":52},"Yang Liu",{"id":81,"slug":82,"hasResults":12,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":61,"sex":18,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":64,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":105},"100408479","role-of-body-composition-in-large-for-gestational-age-infants-lga-with-oral-feeding-difficulty-100408479","NCT04599010","Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty","Pilot Randomized Controlled Trial Comparing FFM-indexed Feeding vs. Standard Feeding in LGA Infants With Oral Feeding Difficulty and Disproportionate Body Composition.","Inclusion Criteria:\n\n* LGA infants with oral feeding difficulty born at ≥ 35 weeks gestation, with FM z-score \\> +1.0 in body composition measurement\n\nExclusion Criteria:\n\n* Infants on any respiratory support, Infants on enteral feeding duration \\> 60 minutes due to hypoglycemia concerns, videofluoroscopic swallow study (VFSS) demonstrating unsafe swallowing function, GI surgical conditions, significant neurological morbidities, and major congenital, genetic syndromes\u002Fanomalies","1 Week","10 Weeks",{"count":90,"type":22},40,[66],"Large for Gestational Age (LGA) infants have excess fat-mass (FM) proportion secondary to prolonged in utero exposure to an energy-rich environment. Our preliminary data suggest that excess FM proportion can be associated with oral feeding delay and a potentially modifiable therapeutic target to improve oral feeding outcomes. The objective of this study is to determine the impact of a short-term Fat-free mass (FFM)-indexed feeding on the oral intake volumes in LGA infants with oral feeding difficulties.",[30,94,95],"Feeding; Difficult, Newborn","Nutrition Disorder, Infant","2026-05-22",{"date":98,"type":45},"2026-05-27",{"date":100,"type":45},"2024-09-26",{"date":102,"type":22},"2027-12-31",{"name":104,"class":52},"Nemours Children's Clinic",2,{"id":107,"slug":108,"hasResults":12,"nctId":109,"briefTitle":110,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":12,"sex":18,"minAge":112,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":64,"phases":115,"briefSummary":116,"conditions":117,"keywords":120,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":53},"100640788","lifestyle-intervention-to-improve-muscle-function-in-older-adults-100640788","NCT07597980","Lifestyle Intervention to Improve Muscle Function in Older Adults","Inclusion Criteria:\n\n1. Age \\> 50 years.\n2. Body mass index (BMI) ≥ 30 kg\u002Fm2.\n3. Homeostatic model assessment of insulin resistance ≥ 3.\n4. Mini-Mental State Examination (MMSE) \\> 25.\n5. Geriatric Depression Scale-15 (GDS-15) \\\u003C 9.\n6. Sedentary (less than 90 minutes\u002Fweek of moderate to vigorous activity).\n7. Ability to provide written informed consent.\n\nExclusion Criteria:\n\n1. Diagnosis of cancer (received within five years) or diabetes (type 1 and 2), or significant musculoskeletal, or cardiovascular, or hepatic, or renal, disease or dysfunction.\n2. Clinically significant gastrointestinal malabsorption syndromes such as chronic diarrhea, celiac disease, or clinically significant abnormal laboratory markers.\n3. Fluctuation in body weight \\> 3 kg in the preceding two months\n4. Condition that impedes testing of the study hypothesis or makes it unsafe to exercise or consume the study foods.","50 Years",{"count":114,"type":22},80,[66],"The goal of this randomized controlled two-arm trial is to determine the effect of a diet and exercise intervention for 12 weeks on body composition, muscle function, and energy balance in 80 adults aged 50 years and over with obesity and insulin resistance. The main questions the trial aims to answer are: Will 12 weeks of a structured nutrition plan + exercise reduce fat mass, improve muscle function, and increase energy deficit compared to the usual diet + exercise. The hypothesis is that 12 weeks of a structured nutrition plan + exercise will reduce fat mass, improve muscle function, and produce greater energy deficit than the usual diet + exercise. Participants will be provided with all meals for 12 weeks and will exercise at the Center under supervision three times each week. Pre and post-intervention, body composition, physical function, and energy deficit will be measured.",[30,118,119],"Physical Function","Energy Balance",[121,122,123,124],"Fat mass","muscle mass","physical function","energy deficit","2026-05-19",{"date":96,"type":45},{"date":128,"type":22},"2026-06",{"date":130,"type":22},"2030-12",{"name":132,"class":52},"Pennington Biomedical Research Center",{"id":134,"slug":135,"hasResults":12,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":139,"eligibilityCriteria":140,"healthyVolunteers":61,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":141,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":143,"conditions":144,"keywords":147,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":53},"100639654","validation-of-a-body-composition-segmentation-software-on-a-diverse-public-ct-scan-cohort-100639654","NCT07600866","Validation of a Body-Composition Segmentation Software on a Diverse Public CT Scan Cohort","Validation of a Body-Composition Segmentation Software (Soma) on a Diverse Cohort of Publicly Available CT Scans","SOMA","Inclusion Criteria:\n\n* Subjects above 16 years or older at the time the source imaging was acquired.\n* De-identified abdominal computed tomography (CT) scan available from one of the six predefined publicly available datasets (autoPET, AMOS, MSD Pancreas, CT-ORG, ENHANCE.PET, or RATIC).\n* Scan covers the third lumbar vertebra (L3) with a contiguous axial slice suitable for L3-level body-composition analysis.\n* Demographic metadata required for stratified sampling (age, sex; BMI where available; clinical context as encoded in source dataset) is present.\n\nExclusion Criteria:\n\n* Subject under 16 years of age at the time the source imaging was acquired.\n* Scan does not include the L3 vertebra or has severe motion artifact, truncation, or metallic artifact precluding analysis at the L3 level.\n* Duplicate or near-duplicate scans of the same subject already included in the cohort.\n* Missing demographic metadata required for at least one stratification axis.",{"count":142,"type":22},200,"This study evaluates the standalone performance of Soma, a deep-learning software developed by Nucleo Research, Inc. for the automated segmentation of body-composition tissues (skeletal muscle, subcutaneous adipose tissue, visceral adipose tissue, and intramuscular adipose tissue) on whole-body computed tomography (CT) images. The aim is to confirm that Soma produces segmentations and tissue-area measurements that agree with a multi-rater expert reference standard, on a diverse cohort representative of demographic and clinical variation. A total of 200 CT scans are sampled by stratified design from a curated pool of 2,066 scans aggregated from six publicly available, de-identified imaging datasets (autoPET, AMOS, MSD Pancreas, CT-ORG, ENHANCE.PET, RATIC). Three board-certified radiologists independently annotate the reference standard at the L3 slice. Primary performance is assessed using the Dice similarity coefficient against the multi-rater reference, with predefined thresholds and BCa bootstrap confidence intervals, both in aggregate and within every demographic and clinical subgroup. Secondary endpoints include Bland-Altman analysis of tissue-area agreement, 95th-percentile Hausdorff distance, Pearson correlation of derived indices, and Cohen's kappa for sarcopenia classification using Skeletal Muscle Index (SMI). The study is fully retrospective on de-identified images, involves no patient contact, and has been determined exempt by Salus IRB (Salus Number 26328) under 45 CFR 46.104(d)(4).",[145,30,146],"Sarcopenia","Obesity",[30,148,149,150,151,152,153,145,154],"CT","Computed Tomography","Segmentation","Deep Learning","Artificial Intelligence","Skeletal Muscle Index","Validation","2026-05-15",{"date":96,"type":45},{"date":158,"type":22},"2026-05-31",{"date":160,"type":22},"2026-06-15",{"name":162,"class":163},"Nucleo Research, Inc.","INDUSTRY",{"id":165,"slug":166,"hasResults":12,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":170,"eligibilityCriteria":171,"healthyVolunteers":61,"sex":18,"minAge":172,"maxAge":173,"enrollmentInfo":174,"targetDuration":4,"studyType":64,"phases":175,"briefSummary":176,"conditions":177,"keywords":182,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":53},"100616740","mediterranean-diet-uptake-and-nutrition-on-child-health-inflammation-and-early-life-symbiosis-munchies-study-100616740","NCT07309536","Mediterranean Diet Uptake and Nutrition on Child Health, Inflammation, and Early-life Symbiosis (MUNCHIES) Study","Mediterranean Diet Uptake and Nutrition on Child Health, Inflammation, and Early-life Symbiosis (MUNCHIES): A Randomized Controlled Trial","MUNCHIES","Inclusion Criteria:\n\n* Parent is ≥19 years of age.\n* Carried a singleton pregnancy.\n* Delivered at term (≥37 weeks gestation).\n* Delivered vaginally or by cesarean section.\n* Infant was born with a birth weight between 2,500 g and 4,500 g.\n* Toddler is between 24 and 36 months of age at enrollment.\n* Parent is able to communicate in English.\n* Parent is willing to adhere to the Mediterranean diet for their toddler for 3 weeks.\n* Parent is willing to participate in a nutrition education program for 3 months.\n* Parent is willing to complete all measurements and provide a stool sample from their toddler.\n\nExclusion Criteria:\n\n* Toddler has food allergies or dietary restrictions (e.g., gluten-free) that make it difficult to follow a Mediterranean diet.\n* Toddler is at high risk for food allergies (e.g., strong family history of multiple food allergies common to the Mediterranean diet).\n* Toddler is already following a Mediterranean diet.\n* Toddler has had recent or active consumption of antibiotics, probiotics, or prebiotic drops.\n* Toddler has an active acute illness, such as fever, diarrhea, or constipation.\n* Toddler was born with a congenital illness or malformation that could affect diet, inflammation, gut health, or body composition.\n* Toddler is currently breastfeeding, formula-feeding, or combination feeding.","24 Months","36 Months",{"count":90,"type":22},[66],"Toddlerhood (ages 2-3) is a critical window when the gut microbiome is still developing and eating habits are being established. Yet, many Canadian toddlers eat diets high in sugar and salt, which may affect long-term health. This study will test whether a MED diet can improve dietary inflammation, gut health, and body composition in toddlers and whether a tailored nutrition education program for parents can help families maintain healthy eating patterns.\n\nIn this study, toddlers will be randomly assigned to a 3-week MED diet or their usual diet. Families in the MED diet group will receive free meal boxes for the 3 weeks, plus guidance from a nutrition researcher through a structured education program. The standard diet group will continue their regular diet with general nutrition advice. Researchers will collect dietary information, body composition assessments, and stool samples to measure gut microbiome composition and metabolites.\n\nThis first study of a controlled diet intervention in toddlers, combining behavioral support, high-quality food provision, and advanced gut microbiome analysis, will help understand how early diet shapes lifelong eating habits and health, guiding public health strategies and precision nutrition approaches to prevent chronic disease from early life.",[178,30,179,180,181],"Gut Microbiome","Adherence","Metabolites","Inflammation",[183,184,185,181],"Dietary patterns","Gastrointestinal microbiome","Body composition","2026-05-11",{"date":188,"type":45},"2026-05-12",{"date":190,"type":22},"2026-07-01",{"date":192,"type":22},"2027-11-01",{"name":194,"class":52},"University of New Brunswick",{"id":196,"slug":197,"hasResults":12,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":61,"sex":18,"minAge":202,"maxAge":203,"enrollmentInfo":204,"targetDuration":4,"studyType":64,"phases":206,"briefSummary":207,"conditions":208,"keywords":212,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":223,"completionDateStruct":224,"leadSponsor":226,"locationsCount":53},"100635450","effects-of-8-week-crossfit-based-concurrent-training-on-fitness-body-composition-and-psychological-outcomes-in-schoolchildren-100635450","NCT07552844","Effects of 8-Week CrossFit-Based Concurrent Training on Fitness, Body Composition, and Psychological Outcomes in Schoolchildren","Effects of an 8-Week CrossFit-Based Concurrent Training Program on Physical Fitness, Body Composition, and Psychological Outcomes in Schoolchildren: A Randomized Controlled Trial Protocol","Inclusion Criteria:\n\n* Age: 7-11 years.\n* Students enrolled at CEIP Pablo García Baena (Córdoba).\n\nFor the experimental group:\n\n* Availability to attend the Triple XXX Box (Polígono Pedroches, C. los Alfareros, Parcel 119, 14014 Córdoba), where both assessments and training sessions will be conducted.\n* Availability to attend training sessions twice per week for the 8-week intervention period.\n* No participation in extracurricular physical activity prior to the start of the CrossFit program.\n\nFor the control group:\n\nNo participation in extracurricular physical activity. Informed consent signed by parents or legal guardians. No medical, psychological, or behavioral contraindications that would prevent participation in physical activity.\n\nExclusion Criteria:\n\n* Children with musculoskeletal injuries, diseases, or medical, psychological, or behavioral conditions that limit physical activity or interfere with the assessment of outcomes.\n* Inability or anticipated difficulty in regularly attending training sessions.\n* Refusal of parents or legal guardians to provide informed consent.","7 Years","11 Years",{"count":205,"type":22},30,[66],"This study examines the effects of an 8-week CrossFit-based concurrent training program in boys and girls aged 7 to 11 years, comparing an experimental group (n=15) with a control group (n=15). The aim is to assess changes in strength, cardiorespiratory fitness, body composition, and psychological variables such as anxiety, stress, and self-esteem, using field-based physical tests (CMJ, Course Navette, handgrip strength, etc.) and validated questionnaires. The study follows a randomized controlled trial design with pre- and post-intervention assessments. The experimental group will complete two weekly CrossFit sessions adapted for children, while the control group will maintain their usual routine without structured physical training. The hypothesis states that the intervention will significantly improve both physical performance and psychological well-being in the experimental group compared to the control group.",[209,210,211,69,30],"Children","Crossfit","Psychology, Child",[213,214,215,216,217,218,69,219],"children","stress","anxiety","exercise training","crossfit","self-esteem","body composition","2026-04-25",{"date":222,"type":45},"2026-04-30",{"date":128,"type":22},{"date":225,"type":22},"2026-07",{"name":227,"class":52},"Maimónides Biomedical Research Institute of Córdoba",{"id":229,"slug":230,"hasResults":12,"nctId":231,"briefTitle":232,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":12,"sex":234,"minAge":19,"maxAge":4,"enrollmentInfo":235,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":237,"conditions":238,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":53},"100614783","the-synergistic-effects-of-menopause-and-hiv-on-cardiovascular-disease-risk-in-women-100614783","NCT07284082","The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women","Inclusion Criteria:\n\n* 90 non-pregnant women with HIV (approximately 30 in each menopausal phase) from the San Francisco MWCCS site.\n\nExclusion Criteria:\n\n* Women who are not virally suppressed (HIV RNA \\>200 copies\u002FmL)\n* Women who are not on antiretroviral therapy\n* Women who have a history of hysterectomy or oophorectomy\n* Women who are receiving treatment for active cancer or tuberculosis","FEMALE",{"count":236,"type":22},90,"Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menopause on cardiovascular disease risk factors such as insulin resistance, hypertension, hyperlipidemia, and carotid atherosclerosis using previously collected data. The investigators will look at underlying causes for cardiovascular diseases worsening in menopausal women with HIV by looking at the role of increased inflammation in the body and whether this is altered by weight. The investigators achieve this by enrolling participants who are willing to undergo a whole body MRI.",[239,240,241,242,30],"HIV","Menopause","Cardiovascular (CV) Risk","Carotid Arteriosclerosis","2026-04-20",{"date":245,"type":45},"2026-04-22",{"date":247,"type":45},"2026-04-17",{"date":249,"type":22},"2030-03-01",{"name":251,"class":52},"University of California, San Francisco",{"id":253,"slug":254,"hasResults":12,"nctId":255,"briefTitle":256,"officialTitle":257,"acronym":258,"eligibilityCriteria":259,"healthyVolunteers":61,"sex":18,"minAge":260,"maxAge":261,"enrollmentInfo":262,"targetDuration":4,"studyType":64,"phases":264,"briefSummary":265,"conditions":266,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":274,"locationsCount":53},"100631610","dose-response-impact-of-geranylgeraniol-gg-supplementation-on-muscle-health-100631610","NCT07502924","Dose-Response Impact of Geranylgeraniol (GG) Supplementation on Muscle Health","Dose-Response Impact of Geranylgeraniol (GG) Supplementation on Muscular Strength, Body Composition, Sex Steroid Hormones and CoQ10 Levels in Healthy Men and Women","GGE","Inclusion Criteria:\n\n* Between 30 and 60 years old.\n* Body mass index values will range from \\>18.5 and \\\u003C29.9 kg\u002Fm2\n* Subject agrees to maintain their existing dietary patterns throughout the study period.\n* Subject agrees to refrain from alcohol, caffeine, and strenuous exercise for 24 hours prior to each test day.\n* Is physically active, defined as at least 30 min of moderate exercise on at least 4 days a week.\n* Avoid consumption of pomegranate juice and avoid consumption of CoQ10, vitamin B3 and its precursors, L-carnitine, MK-4\n* Subject is willing and able to comply with the study protocol.\n* Subject has given voluntary, written, informed consent to participate in the study.\n\nExclusion Criteria:\n\n* BMI \\\u003C18.5 or \\> 29.9 kg\u002Fm2\n* Positive medical history and\u002For is currently being treated for some form of heart disease, cardiovascular disease, kidney disease, renal failure, or has dialysis performed on regular intervals, Type I or Type II diabetes (determined as fasting blood glucose \\> 126 mg\u002FdL), thyroid disease, liver disease or some form of clinically diagnosed hepatic impairment, immune disorder (i.e., HIV\u002FAIDS), or neurological condition or disease.\n* Diagnosed with any affective disorder or other psychiatric disorder that required hospitalization in the prior year.\n* History of cancer (except localized skin cancer without metastases or in situ cervical cancer within 5 years prior to screening visit).\n* Participant has an abnormality or obstruction of the gastrointestinal tract precluding swallowing (e.g., dysphagia) and digestion (e.g., known intestinal malabsorption, celiac disease, inflammatory bowel disease, chronic pancreatitis, steatorrhea)\n* Genetic musculoskeletal and neurologic disorder known to affect skeletal muscle metabolism\n* Has donated blood in past 60 days\n* Diagnosed with or being treated for any endocrinological disorder and\u002For taking hormone boosting supplements (e.g. herbs) or hormone replacement therapy (prescribed\u002Fdoctor ordered or not)\n* Had CoQ10 supplement in past 30 days. Had steroid medication one month before starting the study\n* Currently prescribed for the first time a statin drugs (i.e., Lipitor, Livalo, Crestor, Zocor, etc.) and\u002For a hypertension medication (i.e., Beta-blockers, ACE Inhibitors, Alpha blockers, - Vasodilators, etc.) within the past 6 months or has had their dosage or medication changed within the past 6 months\n* Current smoker (average of \\> 1 pack per week within the past 3 months) or has quit within the past six months. This includes all forms of nicotine\n* Intake of any drugs (prescribed or over the counter) or dietary supplements that are known or are purported to impact energy expenditure or weight loss (caffeine doses \\\u003C300 mg\u002Fday is permissible)\n* Women with a history of hormone-related conditions such as endometriosis, fibroids, polycystic ovary syndrome\n* Women who are pregnant, planning to become pregnant, or lactating currently or within the past six months\n* Have a known sensitivity or allergy to any of the study products\n* History of alcohol or substance abuse in the 12 months prior to screening\n* Receipt or use of an investigational product in another research study within 30 days of beginning the study protocol\n* Has participated in other clinical trials focused on physical and muscle performance within the last year\n* They plan major changes in lifestyle (i.e., diet, dieting, exercise level, travel, etc.) during the study\n* Individuals who regularly compete as part of sanctioned athletic activities or those individuals who regularly train more than 360 minutes of exercise per week\n* Recent history (\\\u003C3 months) of exercise training or weight loss (\\> 5%)\n* Any condition or abnormality that, in the opinion of the investigator, would compromise the safety of the participant or the quality of the study data","30 Years","60 Years",{"count":263,"type":22},70,[66],"This study will evaluate the effects of daily geranylgeraniol (GG) supplementation on muscular strength, body composition, and aerobic capacity in healthy, physically active men and women. Approximately 60 participants aged 30-60 years will be enrolled in a randomized, double-blind, placebo-controlled, parallel-group trial lasting 8 weeks.\n\nParticipants will be assigned to receive either placebo, 150 mg GG, or 300 mg GG daily. Outcome measures will be assessed at baseline, week 4, and week 8 and include maximal strength (1RM bench press and leg press), fat-free mass, muscular endurance, aerobic capacity (VO2peak), and circulating biomarkers related to metabolism and health.",[267,70,30],"Muscle Health","2026-03-25",{"date":270,"type":45},"2026-03-31",{"date":272,"type":45},"2025-03-03",{"date":47,"type":22},{"name":275,"class":52},"Lindenwood University",{"id":277,"slug":278,"hasResults":12,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":4,"eligibilityCriteria":282,"healthyVolunteers":12,"sex":234,"minAge":283,"maxAge":284,"enrollmentInfo":285,"targetDuration":4,"studyType":64,"phases":286,"briefSummary":287,"conditions":288,"keywords":299,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":313,"lastUpdatePostDateStruct":314,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":318,"locationsCount":53},"100572621","wild-blueberries-for-gut-brain-and-cardiometabolic-health-in-prediabetes-100572621","NCT06735651","Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes","Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Female Adults With Prediabetes.","Inclusion Criteria:\n\n* Women aged 20-65 years old\n* Prediabetes (fasting blood glucose 100-125 mg\u002FdL and\u002For HbA1c percentage between 5.7-6.4)\n* Body Mass Index between 25-30 kg\u002Fm\\^2\n\nExclusion Criteria:\n\n* Allergies to berries\n* Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs\n* Active cancer, gastrointestinal, renal, thyroid, stage 1 \\& 2 hypertension and other cardiovascular diseases, neurological diseases, or severe head injury\n* Smoking\n* Consumes greater than 2 alcoholic beverages per day\n* Consumes antioxidant, probiotic, and prebiotic supplements\n* Pregnant or Lactating\n* Actively participating in a weight loss program\n* Currently taking berry supplements or recently participated in another study taking berry supplements","20 Years","65 Years",{"count":205,"type":22},[66],"The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.",[289,290,291,292,293,294,295,296,297,181,298,30],"Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)","Female","Adult","Endothelial Function (Reactive Hyperemia)","Arterial Stiffness","Cognition","Oxidative Stress","Gut Microbiota","Overweight","Microvascular Function",[300,301,302,303,304,305,306,307,308,309,310,311,298,312],"Blueberries","Prediabetes","Insulin Resistance","Functional foods","Dietary intervention","Endothelial function","Vascular function","Cardiovascular health","Metabolic health","Gut microbiota","Cognitive function","Type II diabetes","Wild Blueberries","2026-03-23",{"date":268,"type":45},{"date":316,"type":45},"2024-09-20",{"date":75,"type":22},{"name":319,"class":52},"Georgia State University",{"id":321,"slug":322,"hasResults":12,"nctId":323,"briefTitle":324,"officialTitle":325,"acronym":4,"eligibilityCriteria":326,"healthyVolunteers":61,"sex":327,"minAge":19,"maxAge":328,"enrollmentInfo":329,"targetDuration":4,"studyType":64,"phases":331,"briefSummary":332,"conditions":333,"keywords":335,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":338,"lastUpdatePostDateStruct":339,"startDateStruct":341,"completionDateStruct":343,"leadSponsor":345,"locationsCount":53},"100630205","ems-combined-with-resistance-training-in-weight-lifters-100630205","NCT07484646","EMS Combined With Resistance Training in Weight Lifters","Effects of Electrical Muscle Stimulation Combined With Resistance Training on Muscle Mass, Strength, Body Composition, and Power in Weight Lifters","Inclusion Criteria:\n\n* Male participants aged 18-40 years\n* Resistance training ≥3 times\u002Fweek for at least 1 year\n* Active participation in weightlifting, bodybuilding, or strength athletics\n* Medically cleared for physical activity\n\nExclusion Criteria:\n\n* Neuromuscular disorders\n* Cardiac pacemaker or implantable electronic device\n* Recent musculoskeletal injury (within the last 6 months)\n* Skin sensitivity or allergy to EMS electrodes","MALE","40 Years",{"count":330,"type":22},34,[66],"The purpose of this randomized controlled trial is to determine the effects of Electrical Muscle Stimulation (EMS) combined with resistance training on muscle mass, muscular strength, body composition, and power in trained weightlifters. Participants will be randomly allocated into two groups: one receiving resistance training alone and the other receiving EMS combined with resistance training. The intervention will be conducted for eight weeks, and outcome measures will be assessed at baseline, mid-intervention (4 weeks), and post-intervention (8 weeks). The findings of this study may provide evidence regarding the additional benefits of EMS when combined with conventional resistance training programs in enhancing muscular performance among trained athletes.",[30,334,70],"Muscle Mass",[334,70,30,336,337],"Resistance Training","Electrical Muscle Stimulation","2026-03-16",{"date":340,"type":45},"2026-03-20",{"date":342,"type":45},"2025-12-01",{"date":344,"type":22},"2026-09-01",{"name":346,"class":52},"Riphah International University",{"id":348,"slug":349,"hasResults":12,"nctId":350,"briefTitle":351,"officialTitle":352,"acronym":4,"eligibilityCriteria":353,"healthyVolunteers":12,"sex":234,"minAge":19,"maxAge":4,"enrollmentInfo":354,"targetDuration":356,"studyType":24,"phases":4,"briefSummary":357,"conditions":358,"keywords":362,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":369,"lastUpdatePostDateStruct":370,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":374,"locationsCount":53},"100629294","longitudinal-body-composition-assessment-in-breast-cancer-patients-100629294","NCT07472803","Longitudinal Body Composition Assessment in Breast Cancer Patients","Long-term Evaluation of the Body Composition and the Impact of Resistance and Relaxation Exercise on Muscle Mass and Quality of Life in Patients With Breast Cancer","Inclusion Criteria:\n\n* \\>18 years of age\n* Diagnosed with stage I-III non-metastatic breast cancer within 12 months of diagnosis\n* Scheduled for surgery, chemotherapy, with or without radiotherapy or targeted therapy.\n\nExclusion Criteria:\n\n* Women diagnosed with metastatic (stage IV) breast cancer\n* Women planning to move away from the area or be away for more than 6 months during the study period\n* Women planning to become pregnant during the study period\n* Implantable devices (e.g., pacemaker, nerve stimulator) or surgical implants (e.g., total hip or knee replacements)",{"count":355,"type":22},100,"12 Months","This observational cohort study aims to track longitudinal changes in body composition, including skeletal muscle mass and fat distribution, in patients diagnosed with breast cancer. Following primary surgery and adjuvant therapy, participants will be monitored over a 2-year period.\n\nThe primary objective is to evaluate the natural progression of skeletal muscle mass index (SMI) and metabolic changes in this population. By conducting serial measurements, this study seeks to characterize the longitudinal trends in muscle loss and body composition shifts post-treatment, providing data to better understand the physiological impact of the cancer recovery process.",[359,30,145,360,361],"Breast Neoplasms","Fat Redistribution","Lymphedema",[363,364,30,365,366,367,368],"Breast Cancer Survivors","Post-Treatment Recovery","Longitudinal Cohort Study","Skeletal Muscle Mass Index","Metabolic Monitoring","sarcopenia","2026-03-12",{"date":338,"type":45},{"date":372,"type":45},"2025-05-19",{"date":102,"type":22},{"name":375,"class":52},"Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation",{"id":377,"slug":378,"hasResults":12,"nctId":379,"briefTitle":380,"officialTitle":381,"acronym":382,"eligibilityCriteria":383,"healthyVolunteers":61,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":384,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":386,"conditions":387,"keywords":391,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":397,"lastUpdatePostDateStruct":398,"startDateStruct":400,"completionDateStruct":402,"leadSponsor":404,"locationsCount":53},"100628688","body-composition-and-lifestyles-in-athletes-with-disabilities-100628688","NCT07464899","Body Composition and Lifestyles in Athletes With Disabilities","Anthropometric, Dietary, Exercise, and Supplementation Profile in Athletes With Disabilities (PADES)","PADES","Inclusion Criteria:\n\n* Acceptation of informed consent\n* Have a federation license and at least two years of experience practicing the sport in which they will be classified.\n* Follow a training program with a minimum frequency of three days per week.\n* Have maintained training continuity for at least one month without absences.\n* Any type of disability.\n\nExclusion Criteria:\n\n* No attendance to the evaluations\n* Reporting less than 80% of assistance to physical activity sessions reported by trainer",{"count":385,"type":22},300,"Disability involves limitations that affect mobility and the ability to perform daily activities and achieve competitive goals. It is expected that disability has a significant impact on body composition, including reductions in lean mass and bone mineral content, and increases in fat mass and its distribution. Additionally, the assessment of food and dietary supplement intake among athletes with disabilities remains poorly described, despite its relevance in both sports and health contexts due to the potential benefits of individualized nutritional strategies.\n\nThis research project, entitled Anthropometric, Dietary, Exercise, and Supplementation Profile in Athletes with Disabilities (PADES), aims to describe the anthropometric characteristics, physical exercise practices, and food and supplement intake in Spanish athletes with disabilities. The study seeks to address the current lack of standardized anthropometric data and the limited information on dietary and supplementation patterns in this population, which hinders a comprehensive understanding of the physiological, nutritional, and biomechanical aspects essential for their health and athletic performance. A cross-sectional, descriptive-correlational study will be conducted in Spanish athletes with disabilities recruited through the Spanish Federation of Sports for People with Physical Disabilities (FEDDF), the Spanish Federation of Sports for the Blind (FEDC), and the Spanish Federation of Sports for the Deaf (FEDS).",[388,30,389,390],"Diet Habits","Athlete Assessment","Sport Nutrition",[392,393,394,395,219,396],"sport nutrition","questionnaries","athletes","dietary-nutritional assessment","disability","2026-03-09",{"date":399,"type":45},"2026-03-11",{"date":401,"type":45},"2024-02-01",{"date":403,"type":22},"2030-04-30",{"name":405,"class":52},"University of Alicante",{"id":407,"slug":408,"hasResults":12,"nctId":409,"briefTitle":410,"officialTitle":411,"acronym":412,"eligibilityCriteria":413,"healthyVolunteers":61,"sex":234,"minAge":414,"maxAge":4,"enrollmentInfo":415,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":417,"conditions":418,"keywords":431,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":440,"lastUpdatePostDateStruct":441,"startDateStruct":442,"completionDateStruct":444,"leadSponsor":446,"locationsCount":448},"100628121","breastmilk-and-the-link-to-overweightobesity-and-maternal-diet-in-the-mother-breastmilk-child-triad-100628121","NCT07457515","Breastmilk and the Link to Overweight\u002FObesity and Maternal Diet in the Mother-breastmilk-child Triad","Analysis of the Transmission of Overweight\u002FObesity in the Mother-breastmilk-child Triad in Relation to Maternal Cardiometabolic Status and Diet","BLOOM-Triad","Inclusion Criteria:\n\nfor mother:\n\n* at least 19 years,\n* plan of exclusively or predominantly breastfeeding for 6 months,\n* consent to a sampling of biological material and participate in all planned procedures (for both mother and infant),\n* willingness to finish the follow-up,\n* well-understanding of the Polish language (for non-Polish nationalities); for infants:\n* 1 month or less,\n* clinically healthy,\n* none or one formula feeding per day\n\nExclusion Criteria:\n\nfor mother:\n\n* type 1 or 2 diabetes diagnosed before pregnancy,\n* uncontrolled thyroid disease,\n* breastfeeding more than 1 child or being a milk donor,\n* tobacco\u002Falcohol use during pregnancy or currently,\n* inability to express a sufficient amount of milk; for infants:\n* congenital disease,\n* birth from a multiple pregnancy,\n* preterm birth (\\\u003C37 Hbd).","19 Years",{"count":416,"type":22},165,"The prospective 5-month follow-up study will involve 150 mother-infant dyads grouped based on maternal baseline BMI category (normal weight, overweight, obesity). The investigators plan 3 study visits (1, 3, and 6 months postpartum) with analysis the following parameters and outcomes:\n\n1. maternal anthropometry and body composition;\n2. maternal dietary intake and dietary patterns (with results of biomarker-based validation);\n3. maternal status of lipophilic antioxidants, selected vitamins, and fatty acids profile that may be related to adipose tissue metabolism, inflammation, and cardiometabolic status;\n4. maternal metabolomics, adipokines, insulin, selected biomarkers of inflammation, altered glucose metabolism, and oxidation;\n5. breastmilk composition assessed by systemic approach (macronutrients, fatty acids profile, lipophilic antioxidants, adipokines, hormones, immunological profile, and preliminary lipidomic analysis in part of the study group);\n6. infant growth trajectory, body composition, urine metabolomics, and biomarkers of oxidative stress.\n\nAdditionally, maternal and infant stool, buccal swabs, and human milk samples will be banked for further microbiome analysis studies.",[419,28,420,30,421,422,423,424,425,426,427,428,429,430],"Body Weight","Human Milk\u002FBreastfeeding","Maternal Cardiometabolic Health","Growth & Development","Metabolomic Profile","Infant Body Composition and Metabolism","Carotenoid Status","Fatty Acid Status","Immunologic Markers","Adipokines","Inflammation Biomarkers","Vitamin E",[432,185,433,434,428,435,436,437,181,438,297,146,439],"Lactation","Infant development","Diet","Carotenoids","Fatty acids","Metabolomics","Oxidative stress","Tocopherols","2026-03-02",{"date":397,"type":45},{"date":443,"type":22},"2026-02",{"date":445,"type":22},"2029-09",{"name":447,"class":52},"Warsaw University of Life Sciences",4,{"id":450,"slug":451,"hasResults":12,"nctId":452,"briefTitle":453,"officialTitle":454,"acronym":455,"eligibilityCriteria":456,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":457,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":459,"conditions":460,"keywords":463,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":472,"lastUpdatePostDateStruct":473,"startDateStruct":475,"completionDateStruct":476,"leadSponsor":478,"locationsCount":4},"100626259","ct-body-composition-as-predictor-of-exercise-therapy-outcome-in-peripheral-arterial-disease-100626259","NCT07433309","CT Body Composition as Predictor of Exercise Therapy Outcome in Peripheral Arterial Disease","CT Body Composition Predicts Supervised Exercise Response in Peripheral Arterial Disease: A Protocol","COMPOSE-PAD","Inclusion Criteria:\n\n* Age 18 years or older\n* Confirmed peripheral arterial disease (PAD) defined by at least one of: resting ankle-brachial index (ABI) ≤0.90, duplex ultrasonography demonstrating ≥50% stenosis in a relevant lower extremity vessel, or CT angiography (CTA) or magnetic resonance angiography (MRA) demonstrating flow-limiting lower extremity arterial disease\n* Fontaine stage IIa or IIb intermittent claudication\n* Scheduled for the institutional 36-session supervised exercise therapy (SET) programme\n* Existing CTA with an axial slice at the L3 vertebral level suitable for automated body composition analysis\n* Capacity to provide written informed consent\n\nExclusion Criteria:\n\n* Fontaine stage III or IV peripheral arterial disease (rest pain or tissue loss; critical limb-threatening ischaemia)\n* Ipsilateral lower extremity revascularisation within 6 months prior to enrolment\n* Absolute contraindication to structured exercise (e.g., unstable coronary artery disease, severe pulmonary hypertension, uncontrolled arrhythmia, or other condition precluding participation in a supervised treadmill and resistance exercise programme)\n* Cognitive impairment (Mini-Mental State Examination \\[MMSE\\] score \\\u003C24)\n* Active malignancy or systemic condition expected to substantially alter body composition independently of the exercise intervention during the study period\n* Estimated life expectancy less than 12 months",{"count":458,"type":22},128,"Supervised exercise therapy (SET) is the recommended first treatment for patients with leg artery disease (peripheral arterial disease, PAD) causing pain when walking. However, approximately 40% of patients do not benefit meaningfully and go on to require a procedure to open the blocked arteries within three months. This study investigates whether body composition measurements - specifically the quality of muscle and the amount of belly fat - taken from a CT scan already performed as part of routine care, can identify before treatment begins which patients are unlikely to respond to exercise therapy. If confirmed, this approach would allow doctors to use information from a scan patients are already having, with no additional tests, to better match patients to the right treatment from the start.",[145,30,461,462],"Sarcopenic Obesity","Peripheral Arterial Disease",[464,465,466,467,468,469,470,471],"Peripheral arterial disease","intermittent claudication","supervised exercise therapy","computed tomography body composition","myosteatosis","visceral adipose tissue","sarcopenic obesity","treatment outcome prediction","2026-02-20",{"date":474,"type":45},"2026-02-25",{"date":75,"type":22},{"date":477,"type":22},"2031-01-31",{"name":479,"class":52},"Nemocnice AGEL Trinec-Podlesi a.s.",{"id":481,"slug":482,"hasResults":12,"nctId":483,"briefTitle":484,"officialTitle":484,"acronym":4,"eligibilityCriteria":485,"healthyVolunteers":61,"sex":234,"minAge":328,"maxAge":261,"enrollmentInfo":486,"targetDuration":4,"studyType":64,"phases":488,"briefSummary":489,"conditions":490,"keywords":494,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":499,"lastUpdatePostDateStruct":500,"startDateStruct":501,"completionDateStruct":503,"leadSponsor":505,"locationsCount":53},"100626239","impact-of-supplementation-in-improving-metabolic-health-outcomes-ismos-study-100626239","NCT07433049","Impact of Supplementation in Improving Metabolic Health Outcomes (ISMOS) Study","Inclusion Criteria:\n\n* Women aged 40-60 years old\n* Chinese, Malay or Indian\n* BMI between 23.0-35.0 kg\u002Fm2\n* Proficient in English language\n* Willing to comply with study protocol \\& provide informed consent\n\nExclusion Criteria:\n\n* Pregnant or planning a pregnancy\n* Diagnosis with Diabetes, Polycystic Ovary Syndrome (PCOS), autoimmune diseases, chronic organ failure, severe heart disease, eating disorders and\u002For other medical conditions which in the PI's judgment which may affect study outcomes\n* Fasting glucose value ≥ 7.0 mmol\u002FL\n* Active cancer or treatment of cancer in the last 3 years\n* Participating in other nutritional intervention studies\n* Taking oral corticosteroids, anti-psychotic and\u002For weight loss drugs\n* Having planned hospitalization in the next 12 months\n* Planning to have major diet changes in the next 12 months\n* Taking a medically prescribed supplement(s) that contains 3 or more of the ingredients of the study product\n* Taking a non-prescribed supplement(s) that contains 3 or more of the ingredients of the study product in the last 1 month",{"count":487,"type":22},400,[66],"This study investigates the role of multivitamin and multimineral (MVM) supplementation in improving metabolic, musculoskeletal, and mental health among midlife Asian women aged 40-60 years, a critical period marked by hormonal and physiological transitions from pre- to post-menopause. Evidence from the GUSTO cohort in Singapore has shown that higher plasma levels of vitamins B6, B9, B12, and D are associated with better metabolic profiles, insulin sensitivity, and mental wellbeing, while deficiencies are linked to increased metabolic and psychological risks. Given that vitamin insufficiency and central obesity are highly prevalent among Asian women even at lower BMI, this randomized, double-blind, placebo-controlled trial will evaluate whether 12 months of daily MVM supplementation can reduce MetaboAge and improve metabolic, mental, and muscle health outcomes compared with placebo. Findings will inform preventive strategies for extending health span and mitigating chronic disease risks among midlife women in Asia.",[491,492,493,30],"Glucose Control","Mental Health","Musculoskeletal Health",[495,496,308,497,498],"Multivitamin and mineral supplementation","Women","Mental health","Muscle health","2026-02-19",{"date":474,"type":45},{"date":502,"type":45},"2026-01-20",{"date":504,"type":22},"2028-01",{"name":506,"class":52},"Institute for Human Development and Potential (IHDP), Singapore",{"id":508,"slug":509,"hasResults":12,"nctId":510,"briefTitle":511,"officialTitle":511,"acronym":512,"eligibilityCriteria":513,"healthyVolunteers":61,"sex":234,"minAge":514,"maxAge":261,"enrollmentInfo":515,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":517,"conditions":518,"keywords":522,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":526,"lastUpdatePostDateStruct":527,"startDateStruct":528,"completionDateStruct":529,"leadSponsor":531,"locationsCount":53},"100625465","glp-1ra-effects-on-lean-mass-and-bone-health-in-midlife-women-100625465","NCT07422987","GLP-1RA Effects on Lean Mass and Bone Health in Midlife Women","GLOW","Inclusion Criteria:\n\n* Females\n* Age 35-60 year\n* BMI≥30 or BMI≥27 and at least one cardiometabolic risk factor (dyslipidemia, hypertension, obstructive sleep apnea, metabolic syndrome, fatty liver, PCOS)\n* Newly prescribed a GLP-1RA medication\n* English speaking\n* Body weight stable for the past 6 months\n\nExclusion Criteria:\n\n* Pregnant women\n* Under age 35 or over age 60\n* Born male\n* Cannot consent for themselves\n* Cannot read and speak in English\n* Type 2 diabetes\n* Recently discontinued a GLP-1RA medication (less than 6-months since discontinuing)\n* Contraindications for taking a GLP-1 RA medication (personal or family history of medullary thyroid carcinoma, personal or family history of multiple endocrine neoplasia type 2, personal history of pancreatitis, pregnancy, hypersensitivity to the drug or any component of the drug, active suicidal ideation)\n* Currently taking aromatase inhibitors or selective estrogen receptor modulators (SERMs)","35 Years",{"count":516,"type":22},50,"This study is designed with the interest to learn on the effects of estrogen levels and how it affects body compositions and muscle function in midlife women who are taking a GLP-1RA for weight loss.",[30,519,520,521],"Muscle Function","GLP-1","Estrogen Level",[523,524,525],"Midlife","Women's health","Dietary quality","2026-02-12",{"date":472,"type":45},{"date":526,"type":45},{"date":530,"type":22},"2027-06-30",{"name":532,"class":52},"University of Kansas Medical Center",{"id":534,"slug":535,"hasResults":12,"nctId":536,"briefTitle":537,"officialTitle":538,"acronym":4,"eligibilityCriteria":539,"healthyVolunteers":61,"sex":18,"minAge":112,"maxAge":284,"enrollmentInfo":540,"targetDuration":4,"studyType":64,"phases":541,"briefSummary":542,"conditions":543,"keywords":546,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":548,"lastUpdatePostDateStruct":549,"startDateStruct":551,"completionDateStruct":553,"leadSponsor":555,"locationsCount":53},"100549321","the-association-between-core-temperature-and-health-100549321","NCT06432491","The Association Between Core Temperature and Health","Study to Explore How Core Temperature Reduction Influence Health","Inclusion Criteria:\n\n* Aged between 50 and 65 years old (including 50 and 65)\n* No surgery in the past 6 months\n* Healthy (No metabolic diseases, cardiovascular diseases, lung diseases (COPD, asthma, et al.), endocrine diseases and gastrointestinal diseases)\n* Based in Shenzhen during the whole study period\n* No significant change on body weight in the past 3 months\n\nExclusion Criteria:\n\n* Those who need to take medication for a long term (including diet pills)\n* On a diet\n* Disabled\n* Females who are trying to get pregnant, pregnant, or breastfeeding\n* Presence of a metal implant in the body (e.g. pacemaker)\n* Those with claustrophobia\n* Those with blood phobia, pathological hypotension or hypertension\n* Those who are in other intervention studies",{"count":63,"type":22},[66],"The goal of this clinical trial is to learn if cold water drinking could promote body composition and further extend healthy lifespan in Chinese older adults. The main questions it aims to answer are:\n\n1. Does cold water drinking lower the body fat percentage?\n2. Will cold water drinking positively extend lifespan in a long-term Researchers will compare cold water intervention group to a control group (drinking 37℃ water instead) to see if cold water drinking works to promote health and slow down ageing process.\n\nParticipants will:\n\n1. Drink 4℃ or 37℃ water 4 times (9a.m., 12p.m., 15p.m., 18p.m.) every day for 6 months.\n2. Visit the institute and health checkup department for tests and checkup at baseline, the end of the 3rd month, and the end of 6th month.",[544,30,545],"Body Temperature Changes","Aging",[547,185,545],"Body temperature","2026-01-19",{"date":550,"type":45},"2026-01-21",{"date":552,"type":45},"2025-01-01",{"date":554,"type":22},"2026-12-31",{"name":556,"class":52},"Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences",{"id":558,"slug":559,"hasResults":12,"nctId":560,"briefTitle":561,"officialTitle":562,"acronym":563,"eligibilityCriteria":564,"healthyVolunteers":61,"sex":18,"minAge":112,"maxAge":4,"enrollmentInfo":565,"targetDuration":4,"studyType":64,"phases":567,"briefSummary":568,"conditions":569,"keywords":573,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":577,"lastUpdatePostDateStruct":578,"startDateStruct":580,"completionDateStruct":582,"leadSponsor":584,"locationsCount":4},"100621023","open-space-and-closed-years-100621023","NCT07365228","Open Space and Closed Years","OPEN SPACE AND CLOSED YEARS","OS&CY","Inclusion Criteria:\n\n* physical fitness status which allows active participation in the physical exercising program organized as a tretment\n\nExclusion Criteria:\n\n* health conditions not allowing the participation in treatment program",{"count":566,"type":22},150,[66],"The primary objective of this project is to examine the effects of a specific multicomponent physical activity program (MPAP), conducted in an outdoor setting, on the health and functional-motor status (HFMS) of women over the age of 60. Additionally, the study will investigate the influence of sociodemographic factors (SDF), physical literacy (PL), and health literacy (HL) on the baseline HFMS and the subsequent changes resulting from the KTP.\n\nStudy Methodology\n\nThe program participants will consist of older women (\\>60 years; n=60) whose current HFMS allows for participation in the exercise protocol. They will be divided into two groups:\n\nExperimental Group: Will participate in the MPAP.\n\nControl Group: Will not participate in the MPAP.\n\nThe exercise intervention (MPAP) will include a combination of aerobic activities, strength exercises, balance, and flexibility. It will be conducted two to three times per week across two three-month cycles, separated by a three-month break.\n\nData Collection and Environment Assessments: Sociodemographic factors, physical literacy, and health literacy will be measured at the start of the study. A series of HFMS indicators will be recorded before and after each exercise cycle.\n\nSetting: The MPAP will be performed outdoors in a public park.\n\nProject Significance Beyond analyzing the direct effects of the exercise program and the correlations between the measured variables, this project will contribute to a deeper understanding of the importance of the natural environment in implementing goal-oriented physical activity for the elderly population.",[69,570,571,30,572],"Health Literacy","Lipid Profile","Physical Literacy",[574,575,576],"physical fitness","health status","postmenopausal women","2026-01-15",{"date":579,"type":45},"2026-01-26",{"date":581,"type":22},"2026-01-01",{"date":583,"type":22},"2029-06-01",{"name":585,"class":52},"Goran Kuvacic",{"id":587,"slug":588,"hasResults":12,"nctId":589,"briefTitle":590,"officialTitle":591,"acronym":592,"eligibilityCriteria":593,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":594,"enrollmentInfo":595,"targetDuration":4,"studyType":64,"phases":596,"briefSummary":597,"conditions":598,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":599,"lastUpdatePostDateStruct":600,"startDateStruct":602,"completionDateStruct":604,"leadSponsor":606,"locationsCount":53},"100610389","body-composition-and-exercise-to-prevent-muscle-loss-with-glp1-agonist-treatment-100610389","NCT07226947","Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment","BIA Monitoring and Exercise for the Prevention of Muscle Loss With Incretin Therapy (BICEP Study)","BICEP","Inclusion Criteria\n\n1. Age ≥ 18 years old at time of signing informed consent\n2. Started treatment with incretin therapy (liraglutide, semaglutide, tirzepatide, or retatrutide) within the past 2 months or planning to start this treatment\n\n   a. Potential participants switching GLP1-RA therapies due to inadequate response to a prior treatment will be eligible for enrollment\n3. Able to provide informed consent\n\nExclusion Criteria\n\n1. Current pregnancy (positive urine hCG) or plans to become pregnant in the next 6 months\n2. BMI \\\u003C25 kg\u002Fm2 at the time of screening\n3. Unable to participate in a regular physical exercise program\n4. Implanted pacemaker\n5. Any factors that, in the opinion of the principal investigator, would interfere with the safe completion of the study","99 Years",{"count":355,"type":22},[66],"The goal of this study is to learn if a smartwatch that measures activity level and body composition, combined with exercise reminders, can safely improve strength and muscle mass in people who recently started or are planning to start treatment with incretin therapy (liraglutide, semaglutide, tirzepatide or retatrutide), also known as glucagon-like peptide 1 receptor agonist (GLP-1 RA) medications.",[146,30],"2025-12-23",{"date":601,"type":45},"2025-12-30",{"date":603,"type":45},"2025-11-24",{"date":605,"type":22},"2027-06",{"name":607,"class":52},"Massachusetts General Hospital",{"id":609,"slug":610,"hasResults":12,"nctId":611,"briefTitle":612,"officialTitle":612,"acronym":4,"eligibilityCriteria":613,"healthyVolunteers":61,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":614,"targetDuration":4,"studyType":64,"phases":615,"briefSummary":616,"conditions":617,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":618,"lastUpdatePostDateStruct":619,"startDateStruct":620,"completionDateStruct":622,"leadSponsor":624,"locationsCount":53},"100614644","how-does-continued-use-of-green-light-therapy-impact-outcomes-100614644","NCT07282275","How Does Continued Use of Green Light Therapy Impact Outcomes?","Inclusion Criteria:\n\n* Can read and understand English.\n* US resident.\n* Willing and able to follow the requirements of the protocol.\n\nExclusion Criteria:\n\n* Individuals with eye conditions\n* Individuals not active with Green Light Therapy",{"count":355,"type":22},[66],"Already using Green Light Therapy? Explore how continued use with twice-weekly 20-minute sessions may continue to support positive changes in body composition. Discover whether this non-invasive wellness approach gets better over time to help support energy, balance, and renewal.",[30],"2025-12-19",{"date":599,"type":45},{"date":621,"type":45},"2025-10-21",{"date":623,"type":22},"2026-10-21",{"name":625,"class":163},"Efforia, Inc",{"id":627,"slug":628,"hasResults":12,"nctId":629,"briefTitle":630,"officialTitle":630,"acronym":4,"eligibilityCriteria":631,"healthyVolunteers":61,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":632,"targetDuration":4,"studyType":64,"phases":633,"briefSummary":634,"conditions":635,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":618,"lastUpdatePostDateStruct":636,"startDateStruct":637,"completionDateStruct":639,"leadSponsor":641,"locationsCount":53},"100614632","can-emeraldled-reshape-your-body-with-continued-use-100614632","NCT07282119","Can EmeraldLED Reshape Your Body With Continued Use?","Inclusion Criteria:\n\n* Can read and understand English.\n* US resident.\n* Willing and able to follow the requirements of the protocol.\n\nExclusion Criteria:\n\n* Individuals with eye conditions\n* Individuals not active with EmeraldLED",{"count":355,"type":22},[66],"Already using EmeraldLED? TheGreen Light Therapy study explores how continuing participants' 15-minute sessions, twice a week, may continue to support positive changes in body composition.",[30],{"date":599,"type":45},{"date":638,"type":45},"2025-08-29",{"date":640,"type":22},"2026-08-29",{"name":625,"class":163},{"id":643,"slug":644,"hasResults":12,"nctId":645,"briefTitle":646,"officialTitle":646,"acronym":4,"eligibilityCriteria":647,"healthyVolunteers":61,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":648,"targetDuration":4,"studyType":64,"phases":649,"briefSummary":650,"conditions":651,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":618,"lastUpdatePostDateStruct":652,"startDateStruct":653,"completionDateStruct":655,"leadSponsor":657,"locationsCount":53},"100614629","discover-better-body-composition-with-green-light-100614629","NCT07282080","Discover Better Body Composition With Green Light!","Inclusion Criteria:\n\n* Can read and understand English.\n* US resident.\n* Willing and able to follow the requirements of the protocol.\n\nExclusion Criteria:\n\n-individuals with eye conditions",{"count":355,"type":22},[66],"Investigation into Green Light Therapy study using EmeraldLED for 15-minute sessions, twice a week, to support positive changes in body composition.",[30],{"date":599,"type":45},{"date":654,"type":45},"2025-08-15",{"date":656,"type":22},"2026-08-15",{"name":625,"class":163},{"id":659,"slug":660,"hasResults":12,"nctId":661,"briefTitle":662,"officialTitle":663,"acronym":664,"eligibilityCriteria":665,"healthyVolunteers":61,"sex":234,"minAge":414,"maxAge":666,"enrollmentInfo":667,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":669,"conditions":670,"keywords":675,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":682,"lastUpdatePostDateStruct":683,"startDateStruct":685,"completionDateStruct":687,"leadSponsor":688,"locationsCount":53},"100606081","dietary-patterns-inflammation-zinc-status-and-body-composition-in-multi-ethnic-women-of-reproductive-age-in-jakarta-100606081","NCT07170904","Dietary Patterns, Inflammation, Zinc Status, and Body Composition in Multi-Ethnic Women of Reproductive Age in Jakarta","The Relationship Between Dietary Patterns and Hair Zinc Levels With Body Composition, TNF-α, and Blood Pressure in Women of Reproductive Age (WRA) With Multi-Ethnicities in Jakarta: A Cross-Sectional Study","DIVERSE","Inclusion Criteria:\n\n* Women aged 19-49 years\n* Residing in Jakarta for at least 6 months\n* Currently menstruating (not menopausal)\n* From Minangkabau, Sundanese, Javanese, Betawi, or Chinese ethnicity\n* Not pregnant or breastfeeding at the time of study\n\nExclusion Criteria:\n\n* History of chronic diseases (e.g., diabetes, cardiovascular disease, cancer)\n* Currently on a medically prescribed diet or taking medication affecting nutrient status\n* Any condition interfering with accurate body composition measurement","49 Years",{"count":668,"type":22},188,"This study aims to determine the relationship between dietary patterns and hair zinc levels with body composition, tumor necrosis factor alpha (TNF-α), and blood pressure in women of reproductive age from different ethnic backgrounds in Jakarta, Indonesia (specifically Minangkabau, Sundanese, Javanese, Betawi, and Chinese). Participants are assessed once through dietary assessment, anthropometric measurements, and biological sample collection.",[30,671,672,673,674],"Zinc Status","Dietary Analysis","TNF Alpha","Blood Pressure",[676,677,678,679,219,680,681],"women of reproductive age","dietary assessment","hair zinc","TNF alpha","blood pressure","BOD POD","2025-11-26",{"date":684,"type":45},"2025-12-04",{"date":686,"type":45},"2025-02-03",{"date":270,"type":22},{"name":689,"class":52},"Indonesia University",{"id":691,"slug":692,"hasResults":12,"nctId":693,"briefTitle":694,"officialTitle":695,"acronym":696,"eligibilityCriteria":697,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":698,"enrollmentInfo":699,"targetDuration":4,"studyType":64,"phases":700,"briefSummary":701,"conditions":702,"keywords":711,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":717,"lastUpdatePostDateStruct":718,"startDateStruct":719,"completionDateStruct":721,"leadSponsor":722,"locationsCount":53},"100599273","feasibility-and-potential-efficacy-of-herbs-and-spices-for-improving-dietary-quality-in-college-students-a-pilot-study-100599273","NCT07082348","Feasibility and Potential Efficacy of Herbs and Spices for Improving Dietary Quality in College Students: A Pilot Study","Assessing the Feasibility and Potential Efficacy of Herbs and Spices for Improving Dietary Quality and Adherence to the Dietary Guidelines for Americans in College Students With Poor Dietary Quality: A Pilot Study","HerbSpicesDiet","Inclusion Criteria:\n\n* College students (undergraduate and graduate)\n* Ages 18-39 years\n* BMI 18.5-40 kg\u002Fm\n* Having poor dietary quality (a Rapid Prime Diet Quality Score of 12 or below),\n* Maintain current lifestyle habits (e.g., medications\u002F supplement use, exercise, and sleep), and avoid taking new supplements or medications throughout the study.\n\nExclusion Criteria:\n\n* Individuals diagnosed with myocardial infarction within the past 6 months\n* Uncontrolled hypertension\n* BMIs \\\u003C18.5 or \\>40 kg\u002Fm2\n* Autoimmune disease or immune compromised\n* A recent diagnosis of cancer or under current treatment for cancer\n* A history of kidney stones\n* Having pacemaker\n* Participating in a weight loss program\n* Having a history of any significant GI disease\n* Insulin use\n* Currently on dialysis\n* Currently consuming pro-\u002Fpre-biotics or antiobiotics\n* Diagnosed with unstable chronic metabolic disease\n* Have allergies to any herbs and spices\n* Are pregnant\u002Fnursing\n* Participating in another investigational study\n* Unable or unwilling to give consent","39 Years",{"count":205,"type":22},[66],"The goal of this single-arm feasibility, pilot study is to assess the feasibility, acceptability, and potential effectiveness of the Herbs and Spices Nutrition Education Program (HSNP-focusing on incorporating herbs and spices into the diet for adherence to the DGA's) for determining the scalability of implementing this intervention for a larger scale, more comprehensive study The main questions it aims to answer are:\n\n* What is the feasibility and acceptability of incorporating herbs and spices into the diet along with DGA-focused nutrition education through the HSNP in college students with poor dietary quality?\n* What are the preliminary effects of the HSNP on dietary intake\u002Fquality, cardiometabolic, and gut health in college students with poor dietary quality?\n* What are the barriers associated with HSNP implementation in college students with poor dietary quality?\n\nParticipants will:\n\n* Be asked to come to the study site initially for a Screening Study Visit to confirm eligibility.\n* Be asked to come the clinical study site for a Pre-HSNP and Post-HSNP Study Visit (one week prior starting the HSNP and after week 6 of completing the HSNP) for assessments of cardiometabolic and gut health.\n* Be asked to come to the Nutrition Center for weeks 0 and 3 of the HSNP, where they will receive education on the Dietary Guidelines for Americans and the health benefits of herbs and spices, have a sensory evaluation of foods, be provided budget-friendly recipes and resources, and given take-home herbs, spices, and supporting materials\n* Be asked to complete 3-Day Food Records throughout the 6 week study period for assessment of dietary quality (4 total)",[703,704,705,706,178,707,708,709,429,30,710],"Dietary Quality","Feasibility Studies","College Student","Dietary Guidelines for Americans","Lipid Profiles","Herbs and Spices","Acceptability","Anthropometrics",[712,713,714,715,716],"dietary quality","dietary guidelines for americans","college students","cardiometabolic health","gut microbiome","2025-11-18",{"date":603,"type":45},{"date":720,"type":45},"2025-07-03",{"date":554,"type":22},{"name":723,"class":52},"University of Nevada, Las Vegas"]