[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"body-dysmorphic-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:body-dysmorphic-disorder":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,75,97],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100637872","safety-behavior-fading-versus-progressive-muscle-relaxation-for-appearance-concerns-100637872",false,"NCT07589621","Safety Behavior Fading Versus Progressive Muscle Relaxation for Appearance Concerns","Safety Behavior Fading Versus Progressive Muscle Relaxation for Appearance Concerns: A Randomized Clinical Trial of Digital Interventions","Inclusion Criteria:\n\n* being between the ages of 18 and 65 years old\n* having an internet-capable smart-phone\n* scoring at or above the empirical cutoff for appearance concerns measured by the Social Appearance Anxiety Scale (i.e., 52)\n\nExclusion Criteria:\n\n* changes in psychotropic medication in the last 4 weeks\n* failing attention checks in baseline data collection","ALL","18 Years","65 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"NA","The current study aims to explore the efficacy of a text message based safety behavior fading intervention compared to a progressive muscle relaxation intervention for appearance concerns.",[27,28,29],"Body Dysmorphic Disorder","Eating Disorders","Social Anxiety Disorder","RECRUITING","2026-05-29",{"date":33,"type":34},"2026-06-02","ACTUAL",{"date":31,"type":34},{"date":37,"type":21},"2026-12",{"name":39,"class":40},"Florida State University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":41},"100568213","individual-factors-of-cbt-underlying-success-100568213","NCT06678295","Individual Factors of CBT Underlying Success","Contributions of Self-Focused Attention to Early Warning Indicators of Cognitive Behavioral Therapy Non-Response","I-FOCUS","Inclusion Criteria:\n\nClinical sample (N=110):\n\n1. Men and women, age 18-45\n2. Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV\n3. Fluent in English and willing to provide informed consent.\n\nControl sample (N=50):\n\n1. Men and women, age 18-45\n2. No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV\n3. Meet criteria for low levels of anxiety (GAD-7 score of \\\u003C8) and depression (PHQ-9 score \\\u003C10)\n4. Fluent in English and willing to provide informed consent\n\nExclusion Criteria:\n\nAll groups:\n\n1. Score \\\u003C 80 based on WRAT5 Word Reading Subtest\n2. fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia)\n\n2\\. Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT",true,"45 Years",{"count":53,"type":21},160,[24],"The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.",[29,27],[27,29,58,59,60,61,62,63,64,65],"Social Phobia","Self focused attention","fMRI","CBT","Cognitive Behavior Therapy","BDD","SAD","Neuroimaging","2026-02-13",{"date":68,"type":34},"2026-02-17",{"date":70,"type":34},"2024-10-15",{"date":72,"type":21},"2028-09-30",{"name":74,"class":40},"University of Washington",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":41},"100391180","perceptual-abnormalities-and-their-malleability-in-bdd-100391180","NCT04373629","Perceptual Abnormalities and Their Malleability in BDD","Neural Mechanisms of Perceptual Abnormalities and Their Malleability in Body Dysmorphic Disorder","Inclusion Criteria:\n\nBody dysmorphic disorder: Inclusion:\n\n* males or females\n* ages 18-40\n* meet Diagnostic and Statistical Manual-5 (DSM-5) criteria for Body Dysmorphic Disorder\n* have a Body Dysmorphic Disorder version of the Yale-Brown Obsessive-Compulsive Disorder Scale (BDD-YBOCS) score of ≥20\n* primary appearance concerns of the face or head area\n* medication naïve or medication free for at least 8 weeks prior to enrollment\n\nInclusion Criteria:\n\nSubclinical body dysmorphic disorder: Inclusion:\n\n* males or females\n* ages 18-40\n* have a score on the Dysmorphic Concern Questionnaire of ≥8 \\[1 standard deviation (STD) above population norms\\] - primary appearance concerns of the face or head area\n* medication naïve or medication free for at least 8 weeks prior to enrollment\n\nInclusion Criteria:\n\nHealthy controls: Inclusion\n\n* Healthy males and females from any racial or ethnic background - ages 18-40\n* have a score on the Dysmorphic Concern Questionnaire of \\\u003C8\n\nExclusion Criteria:\n\nBody dysmorphic disorder: Exclusion\n\n* concurrent major Axis I disorders including substance use disorders, aside from anxiety disorders or depressive disorders, as these comorbidities are very common and the sample would otherwise be non-representative; however BDD must be the primary diagnosis.\n* lifetime: bipolar disorder or psychotic disorder.\n* psychotropic medications, aside from a short half-life sedative\u002Fhypnotic for insomnia, or a short half-life benzodiazepine as needed for anxiety but not exceeding a frequency of 3 doses in one week and not to be taken on the days of the training or MRI scan\n* current cognitive-behavioral therapy\n\nExclusion:\n\nSubclinical body dysmorphic disorder: Exclusion\n\n* meet full DSM-5 criteria for Body Dysmorphic Disorder\n* current Axis I disorders including substance use disorders\n* lifetime: bipolar disorder or psychotic disorder\n* psychotropic medications, aside from a short half-life sedative\u002Fhypnotic for insomnia, or a short half-life benzodiazepine as needed for anxiety but not exceeding a frequency of 3 doses in one week and not to be taken on the days of the training or MRI scan\n* current cognitive-behavioral therapy\n\nExclusion Criteria:\n\nHealthy Controls: Exclusion\n\n* Any current Axis I disorder\n* lifetime: bipolar disorder or psychotic disorder\n* Psychiatric medication\n\nExclusion Criteria:\n\nAll participants: Exclusion\n\n* Neurological disorder\n* Pregnancy\n* Current major medical disorders that may affect cerebral metabolism such as diabetes or thyroid disorders - Current risk of suicide with a plan and intent\n* Ferromagnetic metal implantations or devices (electronic implants or devices, infusion pumps, aneurysm clips, metal fragments or foreign bodies, metal prostheses, joints, rods or plates)\n* Visual acuity worse than 20\u002F35 for each eye as determined by Snellen close vision acuity chart (vision will be tested with corrective lenses if participant uses them).","40 Years",{"count":84,"type":21},146,[24],"A core symptom of body dysmorphic disorder (BDD) is perceptual distortions for appearance, which contributes to poor insight and delusionality, limits engagement in treatment, and puts individuals at risk for relapse. Results from this study will provide a comprehensive mechanistic model of brain, behavioral, and emotional contributors to abnormal perceptual processing, as well as how malleable it is with visual modulation techniques. This will lay the groundwork for next-step translational perceptual retraining approaches.",[27],"2025-11-13",{"date":90,"type":34},"2025-11-14",{"date":92,"type":34},"2020-12-01",{"date":94,"type":21},"2026-06-01",{"name":96,"class":40},"Centre for Addiction and Mental Health",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":109,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":41},"100595768","when-the-mirror-is-wrong-100595768","NCT07036744","When The Mirror Is Wrong","When The Mirror Is Wrong: A Multi-Method Efficacy Study Of An Acceptance And Compassion-Based Group Intervention For Body Dysmorphia","Inclusion Criteria:\n\n* Aged between 18-65 years;\n* Fluent Portuguese speakers;\n* Over the cut-off score for the AAI (≥ 21) and the DCQ (≥ 9);\n\nExclusion Criteria:\n\n* Pregnant;\n* If medicated, not stabilized for at least 2 months\n* Currently under other clinical psychology intervention;\n* Current suicidal ideation;",{"count":105,"type":21},16,[24],"Body Dysmorphic Disorder (BDD) is a severe psychiatric condition characterized by persistent and intrusive preoccupations with perceived flaws in physical appearance, which are typically unnoticeable or appear minor to others. BDD is associated with significant psychological distress, functional impairment, and reduced quality of life. Despite its prevalence and clinical severity, BDD remains frequently underdiagnosed and misdiagnosed. While Cognitive Behavioural Therapy (CBT) and Selective Serotonin Reuptake Inhibitors (SSRIs) are currently considered standard treatments, emerging evidence suggests that third-wave psychotherapies, such as Acceptance and Commitment Therapy (ACT) and Compassion-Focused Interventions, may offer additional benefits.\n\nThis project aims to advance clinical care and scientific understanding of BDD by developing, implementing, and evaluating the preliminary efficacy of MIND-over-MIRROR-a novel group-based psychological intervention integrating ACT and compassion-based strategies for individuals exhibiting high levels of BDD symptomatology. The intervention consists of eight weekly sessions and one follow-up booster session, delivered in an online or hybrid format. A randomized feasibility study will be conducted to examine the intervention's acceptability, practicality, and preliminary clinical efficacy in adults aged 18 to 65 years. A multi-method assessment framework will be employed, with self-report measures collected at baseline, post-intervention, and 3-month follow-up. Additionally, participants from experimental and control groups will report on their weekly BDD symptomatology.\n\nParticipants in the intervention group who consent will also undergo computerized behavioural tasks and functional neuroimaging using functional near-infrared spectroscopy (fNIRS) to explore neural and cognitive correlates of treatment outcomes. Improvements are expected in core clinical outcomes, including BDD symptom severity, and it is hypothesized that changes in targeted psychological processes (e.g., self-compassion) will mediate these effects. This study will contribute novel and clinically relevant data regarding the feasibility and potential effectiveness of contextual behavioural therapies for BDD, with implications for both research and practice.",[27],[27,110,111,112,113,114],"Dysmorphic Concern","Acceptance and Commitment Therapy","Compassion","Psychological Flexibility","online group intervention","2025-06-25",{"date":117,"type":34},"2025-06-29",{"date":119,"type":34},"2025-01-29",{"date":121,"type":21},"2026-01-30",{"name":123,"class":40},"University of Coimbra"]