[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bone-atrophy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bone-atrophy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100549470","bone-augmentation-using-calvarial-versus-iliac-crest-bone-blocks-100549470",false,"NCT06434441","Bone Augmentation Using Calvarial Versus Iliac Crest Bone Blocks.","Radiographic Assessment of Horizontal Bone Augmentation of Full Atrophic Maxillary Alveolar Ridges Using Calvarial Versus Iliac Crest Bone Blocks:","Inclusion Criteria:\n\n* Patients with the clinical and radiographic interpretation of horizontal maxillary ridge deficiency of less than 5 mm\n\nExclusion Criteria:\n\n* Any previous maxillary reconstructive or dental implant treatment.\n* Any local pathologic lesion or systemic disease that would affect the typical pattern of bone healing.","ALL","20 Years","55 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate and compare the quantity of the radiographic horizontal bone gain of severely deficient complete maxillary ridges reconstructed by bone block harvest from the iliac crest versus the calvarial bones",[27],"Bone Atrophy",[29,30,31,32],"Bone graft","Iliac crest blocks","Calverial bone blocks","Horizontal bone gain","RECRUITING","2025-01-19",{"date":36,"type":37},"2025-01-22","ACTUAL",{"date":39,"type":37},"2023-08-10",{"date":41,"type":21},"2025-03-01",{"name":43,"class":44},"Beni-Suef University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":45},"100569522","submerged-vs-non-submerged-guided-bone-regeneration-simultaneous-to-implant-placement-100569522","NCT06695338","Submerged Vs Non-Submerged Guided Bone Regeneration Simultaneous to Implant Placement.","Inclusion Criteria:\n\n* • Men and women over 18 years old.\n\n  * Patients requiring single-unit implant restoration in any tooth site of the maxilla and mandible in between teeth.\n  * Anticipation of a peri-implant buccal osseous dehiscence by means of a CT imaging (cone-beam computed tomography, CBCT) with a maximum vertical dimension height (VDH) of 50%.\n  * Presence of adjacent teeth.\n  * Presence of antagonist teeth.\n  * Minimum primary stability of 25Ncm.\n  * Non-smokers or light smokers (\\\u003C 10 cigarettes per day).\n  * Absence of systemic diseases that could influence the outcome of the therapy (i.e., uncontrolled diabetes mellitus, osteoporosis, biphosphonate medication).\n  * Tooth extraction performed at least 4 months before implant placement.\n  * Good level of oral hygiene (Plaque Index \\\u003C 25%) (Löe, 1967)\n  * Written informed consent signed.\n  * Keratinized mucosa of at least 2mm on the buccal and lingual of the implant.\n\nExclusion Criteria:\n\n* Implant surgery requiring sinus lift procedure.\n\n  * Previous bone augmentation at the implant site.\n  * Active periodontal disease.\n  * Acute infection at the rehabilitation site.\n  * Long-term non-steroidal anti-inflammatory drug therapy (3 months).\n  * Lactating females or currently pregnancy.\n  * Severe cognitive or psychiatric disorders.\n  * Unwillingness to return for follow-up examination.",true,"18 Years",{"count":55,"type":21},32,[24],"Dental implants are worldwide recognized one of the best manners to replace lost or hopeless prognosis teeth. There are different variables that creates proper conditions for long-term prognosis of implant treatments.\n\nImplant position and surrounding bone around them, have been described in scientific literature to be key factors in the longevity of those treatments.\n\nIt has to be defined the \\"critical bone thickness\\" around implants. It basically means that implants has to be completely surrounded by bone, that will serve as protection. If the implants are not surrounded by bone, procedures as guided bone regeneration may be performed.\n\nThose procedures can be executed before or simultaneously during the implant placement. In the standard procedure, the simultaneous guided bone regeneration during implant placement requires to leave the implant and the regeneration healing below the gingiva, needing a second surgery for accesing to those implants.\n\nIn this randomized controlled trial the hypothesis is to discover if not submerging this regenerations may show the same results than submerged ones.\n\nFor that, the objective is to study the different variables around these regeneration to evaluate the performance of non-submerged protocol.",[59,60,61,27],"Guided Bone Regeneration","Dental Implant","Submerged Regeneration","NOT_YET_RECRUITING","2024-11-16",{"date":65,"type":37},"2024-11-19",{"date":67,"type":21},"2024-12-15",{"date":69,"type":21},"2026-06-06",{"name":71,"class":44},"Universitat Internacional de Catalunya",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":45},"100558561","phase-1-pilot-study-on-the-effectiveness-of-a-flexible-hydroxyapatite-based-composite-for-jaw-bone-regeneration-100558561","NCT06552715","Pilot Study on the Effectiveness of a Flexible Hydroxyapatite-Based Composite for Jaw Bone Regeneration","Pilot Clinical Study on the Efficacy of a Flexible Hydroxyapatite-Based Composite for the Regeneration of Jaw Bone Defects","Flexi2024","Inclusion Criteria:\n\n* Patients with partially edentulous and atrophic jaws, requiring implant-prosthetic rehabilitation (from 1 to 3 implants), classified as Seibert Class II or III, and needing a GBR bone regeneration intervention with defects not exceeding 7 mm in height\n* Age 18 years or older\n* Obtaining informed consent\n\nExclusion Criteria:\n\n* Patients who have received radiation therapy to the head and neck with more than 70 Gray.\n* Immunocompromised and immunosuppressed patients.\n* Patients treated with or currently receiving intravenous amino-bisphosphonates.\n* Patients with poor oral hygiene and lack of motivation.\n* Uncontrolled diabetes.\n* Pregnancy or breastfeeding.\n* Drug or alcohol dependence.\n* Psychiatric conditions that contraindicate surgical treatment.\n* Limited mouth opening (less than 3.5 cm distance between the two arches in the anterior area).\n* Patients with acute or chronic inflammation\u002Finfection at the implant site.\n* Patients referred solely for implant placement.",{"count":81,"type":21},20,[83],"PHASE1","Following a review of the scientific literature, it was found that there are no clinical studies but only in vitro and in vivo studies, which show promising results in terms of bone formation and integration. However, it is necessary to evaluate how well the regenerated bone maintains its structural integrity over time, considering masticatory function and real-life biomechanics. Factors such as mechanical load, remodeling dynamics, and interactions with surrounding tissues could influence the long-term stability of the regenerated bone. Additionally, another important aspect to study is the potential complications and adverse effects associated with the use of the flexible HAp-based composite.",[27,86,87],"Edentulism","Bone Regeneration",[89,90,91],"bone regeneration","dental implants","jaws atrophy","2024-08-09",{"date":94,"type":37},"2024-08-14",{"date":96,"type":21},"2024-09",{"date":98,"type":21},"2025-09",{"name":100,"class":44},"University of Bologna"]