[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bone-augmentation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bone-augmentation":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,49,66,93,117,141,158,180,205],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100606742","evaluation-of-the-safety-and-performance-of-the-neocement-inject-p-a-prospective-observational-study-in-dental-area-100606742",false,"NCT07179510","Evaluation of the Safety and Performance of the Neocement® Inject P: A Prospective Observational Study in Dental Area","NeoInjDent01","Inclusion Criteria:\n\n* Adult males or females (age \\> 18 years old);\n* Patients who are able to sign an informed consent form (for data collection);\n* Patients undergoing reconstructive dental surgery and indicated for the use of Neocement® Inject P;\n\nExclusion Criteria:\n\n* Patients who are unable to understand consent and the objectives of the study;\n* Signs of local or systemic acute\u002F active or chronic infections;\n* Metabolic affections;\n* Severe degenerative diseases, conditions in which general bone grafting is not advisable;\n* Implementation sites that allow product migration;\n* Conditions which require structural support in the skeletal system;\n* Conditions where the implantation site is unstable and not rigidly fixated;\n* Sensibility to the implantable materials;\n* Known hypersensitivity to the implant material.","ALL","18 Years",{"count":19,"type":20},66,"ESTIMATED","OBSERVATIONAL","This study aims to collect real-world clinical data to gather information on the performance and safety of the Neocement® Inject P when used according to its intended purpose and current clinical applications. The results of the clinical study will serve as clinical evidence for the device's clinical evaluation.",[24],"Bone Augmentation",[26,27,28,29,30,31,32,33,34,35],"prospective observational clinical study","bone substitute","bone defects","real-world clinical data","safety","performance","medical device","reconstructive dental surgeries","Neocement® Inject P","calcium phosphates","RECRUITING","2026-06-17",{"date":39,"type":40},"2026-06-18","ACTUAL",{"date":42,"type":40},"2025-10-06",{"date":44,"type":20},"2027-10",{"name":46,"class":47},"Bioceramed","INDUSTRY",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":62,"startDateStruct":63,"completionDateStruct":64,"leadSponsor":65,"locationsCount":48},"100606741","evaluation-of-the-safety-and-performance-of-the-neobone-a-prospective-observational-study-in-dental-area-100606741","NCT07179497","Evaluation of the Safety and Performance of the Neobone®: A Prospective Observational Study in Dental Area","NeoDent01","Inclusion Criteria:\n\n* Adult males or females (age \\> 18 years old);\n* Patients who are able to sign an informed consent form (for data collection);\n* Patients undergoing reconstructive dental surgery and indicated for the use of Neobone®;\n\nExclusion Criteria:\n\n* Patients who are unable to understand consent and the objectives of the study;\n* Signs of local or systemic acute\u002F active or chronic infections;\n* Metabolic affections;\n* Severe degenerative diseases, conditions in which general bone grafting is not advisable;\n* Implementation sites that allow product migration;\n* Conditions which require structural support in the skeletal system;\n* Conditions where the implantation site is unstable and not rigidly fixated;\n* Sensibility to the implantable materials;\n* Known hypersensitivity to the implant material.",{"count":19,"type":20},"This study aims to collect real-world clinical data to gather information on the performance and safety of the Neobone® when used according to its intended purpose and current clinical applications. The results of the clinical study will serve as clinical evidence for the device's clinical evaluation.",[24],[26,27,28,60,61,29,30,31,32,33],"hydroxyapatite and beta tricalcium phosphate","Neobone®",{"date":39,"type":40},{"date":42,"type":40},{"date":44,"type":20},{"name":46,"class":47},{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":4,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":92},"100599007","effect-of-bone-augmentation-simultaneous-to-implant-removal-on-the-prognosis-of-reimplantation-at-the-same-site-100599007","NCT07078890","Effect of Bone Augmentation Simultaneous to Implant Removal on the Prognosis of Reimplantation at the Same Site","Inclusion Criteria:\n\n* 1\\. Age greater than 18 years 2. Implant failure requiring removal 3. Plan to reimplant in the same site 4. Periodontal health, or stabilized periodontitis after treatment\n\nExclusion Criteria:\n\n* 1\\. Uncontrolled metabolic diseases 2. Taking medications that have an effect on bone metabolism 3. The implant has detached at the time of consultation 4. Do not consent to reimplant in the same site 5. Unwillingness to participate in the follow-up of this study 6. Other conditions that do not qualify for implant therapy","90 Years",{"count":74,"type":20},40,"INTERVENTIONAL",[77],"NA","The aim of this study was to investigate the effect of bone augmentation simultaneous to implant removal on the prognosis of reimplantation at the same sites, providing recommendations for management strategies after failed implant removal.",[80,24,81],"Implant Failure","Prognosis","2025-07-13",{"date":84,"type":40},"2025-07-22",{"date":86,"type":40},"2025-03-12",{"date":88,"type":20},"2027-08",{"name":90,"class":91},"The Dental Hospital of Zhejiang University School of Medicine","OTHER",3,{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":100,"sex":16,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":4,"studyType":75,"phases":105,"briefSummary":106,"conditions":107,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":48},"100585328","reconstruction-of-deficient-maxillary-ridges-using-retromolar-blocks-with-and-without-collagen-membrane-100585328","NCT06900933","Reconstruction of Deficient Maxillary Ridges Using Retromolar Blocks With and Without Collagen Membrane","Reconstruction of Horizontally Deficient Atrophic Maxillary Ridges Using Retromolar Blocks With and Without Coverage Using Collagen Membrane (Randomized Clinical Trials)","Inclusion Criteria:\n\n* Patients with maxillary residual alveolar bone height not less than 8 mm.\n* Alveolar bone width from less than or equal 5 mm.\n* Both genders.\n* At least missing single tooth.\n* Previous Failed Implants.\n* Previous Failed Grafting.\n\nExclusion Criteria:\n\n* • Heavy smokers more than 20 cigarettes per day.\n\n  * Patients with alcohol abuse\n  * Patients with narcotic abuse.\n  * Patients with bone disease that may affect normal healing, example; hyperparathyroidism.\n  * Patients had radiotherapy and chemotherapy in head and neck.\n  * Patients had neoplasms in sites to be grafted.\n  * Patients with Metabolic diseases uncontrolled diabetic patients, Glycated hemoglobin (Hb A1c) more than 7 mg\\\\dl.\n  * Pregnant females.\n  * Patients with Para functional habits, apprehensive and non-cooperative.\n  * Bone pathology related to the site to be grafted.\n  * Psychological problems, stress situation (socially or professionally), emotional instability, and unrealistic patients' expectations.\n  * Intraoral soft and hard tissue pathology.\n  * Systemic condition that contraindicate implant placement.\n  * Under the age of 18 years.",true,"20 Years","40 Years",{"count":104,"type":20},30,[77],"Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in terms of bone quantity?",[24],"2025-07-12",{"date":110,"type":40},"2025-07-16",{"date":112,"type":40},"2025-05-28",{"date":114,"type":20},"2026-02-15",{"name":116,"class":91},"Cairo University",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":16,"minAge":101,"maxAge":124,"enrollmentInfo":125,"targetDuration":4,"studyType":75,"phases":127,"briefSummary":128,"conditions":129,"keywords":131,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":135,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":48},"100584585","one-stage-ridge-splitting-using-2-different-techniques-in-maxilla-100584585","NCT06891261","One Stage Ridge Splitting Using 2 Different Techniques in Maxilla","Evaluation of Endosseous Implants in One Stage Ridge Splitting Using the Conventional Technique Versus the Use of Piezo Surgery in the Maxilla","Inclusion Criteria:\n\n* Patients with maxilla residual alveolar bone height not less than 8 mm.\n* Alveolar bone width from 5mm to 3mm.\n* Both genders.\n* At least single missing tooth.\n* Previous failed implants.\n* Tapered or cylinder cross sectioned alveolar bone defect pattern.\n\nExclusion Criteria:\n\n* Heavy smokers more than 20 cigarettes per day.\n* Patients with bone disease that may affect normal healing, example; hyperparathyroidism.\n* Patients had radiotherapy and chemotherapy in head and neck.\n* Patients had neoplasms in sites to be grafted.\n* Patients with Metabolic diseases uncontrolled diabetic patients, Glycated hemoglobin (Hb A1c) more than 7 mg\\\\dl.\n* Pregnant females.\n* Patients with Para functional habits, apprehensive and non-cooperative.\n* Bone pathology related to the site to be grafted.\n* Psychological problems, stress situation (socially or professionally), emotional instability, and unrealistic patients' expectations.\n* Intraoral soft and hard tissue pathology.\n* Systemic condition that contraindicates implant placement.\n* Under the age of 18 years.\n* Hourglass defects or defects with bone concavities and or undercuts.","48 Years",{"count":126,"type":20},20,[77],"* The selected patients will be informed of the nature of the research work and informed consent will be obtained.\n* Patients of both groups will be subjected to CBCT.\n* Intra operative procedures (for both groups) followed by CBCT will be taken for every patient after 4 months.\n* Infiltration local anesthesia will be given to the patient (Articaine 4% 1:100 000 epinephrine)\n\nBoth the study and control group will receive:\n\n* In Recipient site, full thickness mucoperiosteal flap pyramidal flap, reflection using mucoperiosteal elevator.\n* The defective site is reevaluated.\n* Flap advancement inorder to allow tension free flap closure.\n* In the Study group: Piezo surgery bone inserts is used to cut crestal osteotomies.\n* In the Control group: Bone discs diameter is used.\n* Followed by, the use of bone chisels.\n* The point and pilot implant drills are used followed by bone expanders. Based on the preexisting bone, the defect morphology and bone quality. The implant is submerged below the alveolar crest to compensate for crestal bone resorption.\n* Following partial immobilization of the buccal bone segment either book or island pattern. The fixture is inserted submerged below the alveolar bone crest.\n\nFollowed by bone smoothening and roundation under external saline irrigation at recommended speed of 38000rpm and gear ratio 1:1 calibrated on fesiodespenser.\n\n* Xenogenic bone particle size of 0.5 mm to 1mm is going to be condensed into the dead space.\n* Recheck adequate flap advancement to allow tension free closure.\n* Double line closure using horizontal mattress followed by interrupted sutures to allow contact area and wound edge eversion.",[130,24],"Ridge Augmentation",[132,133,134],"ridge augmentation","One stage ridge splitting in maxilla.","Piezo Surgery",{"date":110,"type":40},{"date":137,"type":40},"2025-02-26",{"date":139,"type":20},"2025-10-31",{"name":116,"class":91},{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":11,"sex":16,"minAge":101,"maxAge":124,"enrollmentInfo":148,"targetDuration":4,"studyType":75,"phases":149,"briefSummary":150,"conditions":151,"keywords":152,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":154,"startDateStruct":155,"completionDateStruct":156,"leadSponsor":157,"locationsCount":48},"100584589","one-stage-ridge-splitting-using-2-different-techniques-in-the-posterior-mandible-100584589","NCT06891313","One Stage Ridge Splitting Using 2 Different Techniques in the Posterior Mandible","Evaluation of Endosseous Implants in One Stage Ridge Splitting Using the Conventional Technique Versus the Use of Piezo Surgery in the Posterior Mandible Region (Randomized Clinical Trial)","Inclusion Criteria:\n\n* Patients with mandibular residual alveolar bone height not less than 8 mm.\n* Alveolar bone width from 5mm to 3mm.\n* Both genders.\n* At least single missing tooth.\n* Previous failed implants.\n* Tapered or cylinder cross sectioned alveolar bone defect pattern.\n\nExclusion Criteria:\n\n* Heavy smokers more than 20 cigarettes per day.\n* Patients with bone disease that may affect normal healing, example; hyperparathyroidism.\n* Patients had radiotherapy and chemotherapy in head and neck.\n* Patients had neoplasms in sites to be grafted.\n* Patients with Metabolic diseases uncontrolled diabetic patients, Glycated hemoglobin (Hb A1c) more than 7 mg\\\\dl.\n* Pregnant females.\n* Patients with Para functional habits, apprehensive and non-cooperative.\n* Bone pathology related to the site to be grafted.\n* Psychological problems, stress situation (socially or professionally), emotional instability, and unrealistic patients' expectations.\n* Intraoral soft and hard tissue pathology.\n* Systemic condition that contraindicates implant placement.\n* Under the age of 18 years.\n* Hourglass defects or defects with bone concavities and or undercuts.",{"count":126,"type":20},[77],"The selected patients will be informed of the nature of the research work and informed consent will be obtained.\n\nThe control group ridge splitting with simultaneous implants using the conventional technique and study group ridge splitting with simultaneous implants using the piezo surgery.\n\n* Pre operative procedures Patients of both groups will be subjected to CBCT.\n* Intra operative procedures (for both groups) followed by CBCT will be taken for every patient after 4 months.\n* Infiltration local anesthesia will be given to the patient (Articaine 4% 1:100 000 epinephrine).\n\nBoth the study and control group will receive:\n\n* In Recipient site, incision of full thickness mucoperiosteal flap inorder to obtain, three-line pyramidal flap, followed by flap reflection.\n* The defective site is reevaluated.\n* Flap advancement using periosteal releasing incision.\n* In the Study group: Piezo surgery bone inserts are used.\n* In the Control group: Bone discs diameter are used.\n* Followed by bone chisels.\n* The point and pilot implant drills are used followed by the sequential use of bone expanders. Based on the preexisting bone, the defect morphology and bone quality. The implant is submerged below the alveolar crest.\n* The fixture is inserted submerged below the alveolar bone crest followed by bone smoothening and roundation under external saline irrigation at recommended speed of 38000rpm and gear ratio 1:1 calibrated on fesiodespenser.\n* Xenogenic bone particle size of 0.5 mm to 1mm is going to be condensed into the dead space.\n* Recheck adequate flap advancement.\n* Double line closure using horizontal mattress sutures followed by interrupted sutures on top to allow contact area and wound edge eversion.",[130,24],[132,153,134],"One stage ridge splitting in posterior mandible.",{"date":110,"type":40},{"date":137,"type":40},{"date":139,"type":20},{"name":116,"class":91},{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":11,"sex":16,"minAge":101,"maxAge":124,"enrollmentInfo":165,"targetDuration":4,"studyType":75,"phases":166,"briefSummary":167,"conditions":168,"keywords":169,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":48},"100573488","reconstruction-of-deficient-atrophic-ridges-using-guide-bone-regeneration-technique-100573488","NCT06746935","Reconstruction of Deficient Atrophic Ridges Using Guide Bone Regeneration Technique","Reconstruction of Deficient Atrophic Ridges Using Guided Bone Regeneration Technique With Native Collagen Membrane and Polytetrafluoroethylene Membrane (Randomized Clinical Trial)","Inclusion Criteria:\n\n* Patients with maxillary residual alveolar bone height not less than 8 mm.\n* Alveolar bone width from less than or equal 5 mm.\n* Both sexes.\n* At least missing single tooth.\n* Previous Failed Implants.\n* Previous Failed Grafting.\n\nExclusion Criteria:\n\n* Heavy smokers more than 20 cigarettes per day.\n* Patients with bone disease that may affect normal healing, example; hyperparathyroidism.\n* Patients had radiotherapy and chemotherapy in head and neck.\n* Patients had neoplasms in sites to be grafted.\n* Patients with Metabolic diseases uncontrolled diabetic patients, Glycated hemoglobin (Hb A1c) more than 7 mg\\\\dl.",{"count":126,"type":20},[77],"patients will be informed of the nature of the research work and informed consent will be obtained then randomized in 2 groups. Mixture 1:1 autogenous and xenogenic bone covered with Polytetrafluoroethylene membrane control group and study group p covered with native collagen membrane.\n\n* Patients of both groups will be subjected to CBCT (diagnostic for upper arch), diagnostic wax-up and stent fabrication.\n* Intra operative procedures (for both groups) followed by CBCT will be taken for every patient after 4 months.\n\nBoth the study and control group will receive:\n\n* In Recipient site, using 15C blade on Bard Parker handle incision of full thickness mucoperiosteal flap inorder to obtain, three-line pyramidal flap, reflection using mucoperiosteal elevator molt 9.\n* The defective site is reevaluated after its primary evaluation on CBCT using UNC (University of North Carolina) periodontal probe and a template is cut using sterile suture pack, prior to donor site preparation.\n* Flap advancement using periosteal releasing incision inorder to allow later tension free flap closure.\n* In Donor site, mucoperiosteal flap is done, auto chip maker (ACM) is used for autogenous bone harvesting.\n* Autogenous particulate bone graft is obtained using auto chip maker bur (ACM), in implant contra 20:1 using surgical motor recommended drilling speed 100 rpm and maximum torque 50 Ncm. as well as, using bone scrapper in push direction.\n* Xenogenic bone graft particles (De-proteinized bovine bone mineral small granules (0.25-1 mm). is added to the autogenous bone particles to obtain homogenous mixture ratio 1:1.\n* The gold standard is a mixture of autogenous bone containing viable cells and xenogenic bone which has slower rate of resorption is to be placed in recipient decorticated site and covered by PTFE membrane.\n* The assemble is to be fixed by titanium bone tacks of diameter 2.5 mm and length 3.5 mm, to avoid micro movements of particulate bone assembly.\n* In the Study group: The assemble is going to be covered by resorbable collagen membrane and fixed by tacks.\n* Recheck adequate flap advancement by visualizing passive flap approximation, to allow tension free closure.\n* Double line closure using horizontal mattress placed 5mm away from flap margins followed by interrupted sutures on top to allow contact area which is preferred to point contact and wound edge eversion.",[130,24],[132,170,171],"Polytetrafluoroethylene","native collagen membrane","2025-02-16",{"date":174,"type":40},"2025-02-19",{"date":176,"type":40},"2025-01-01",{"date":178,"type":20},"2025-10-29",{"name":116,"class":91},{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":187,"enrollmentInfo":188,"targetDuration":4,"studyType":75,"phases":190,"briefSummary":191,"conditions":192,"keywords":4,"overallStatus":195,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":4},"100557529","socket-preservation---a-randomized-clinical-implementation-in-a-student-setting-100557529","NCT06539299","Socket Preservation - A Randomized Clinical Implementation in a Student Setting","Socket Preservation - How Successful is the Method for Inexperienced Practitioners? A Randomized Clinical Implementation in a Student Setting","Inclusion Criteria:\n\n* Study participants have signed patient information and consent form\n* Age between 18-65 years, all genders included\n* Study participants who are considering a planned extraction of a mandibular posterior tooth with subsequent treatment with an implant\n* Study participants with medical and anatomical conditions that correspond to the applicable instructions for use\n* Study participants agree to student treatment\n\nExclusion Criteria:\n\n* Study participants under 18 years of age\n* Study participants with allergies or undesirable reactions to the materials used - Patients with uncontrolled diabetes mellitus (HbA1C value \\>8%)\n* Heavy smokers (\\>10 cigs\u002Fday)\n* Previous general medical conditions that influence bone metabolism (Bone metabolic diseases such as osteopetrosis, osteomalacia, Paget's disease, metabolic diseases such as hyperthyroidism, renal osteopathy, oophorectomy, uncontrolled diabetes mellitus type 2), malignant neoplasms, chemotherapy\u002Fradiation therapy in the head and neck area and immunocompromised patients)\n* which can be determined clinically or radiologically pathological symptoms in the oral cavity or on the alveolar processes or the adjacent regions, untreated acute or chronic disease of the periodontium, untreated disease of the oral mucosa - drug abuse, alcohol disease or abuse","65 Years",{"count":189,"type":20},51,[77],"Preserving the ridge dimension after tooth extraction aims to avoid the need for bone augmentation procedures before implant placement. This study aims to show that socket preservation procedure is a safe, easy and predictable method that stabilizes the bone situation when late implantation is planned.",[193,194,24],"Alveolar Bone Loss","Dental Implant","NOT_YET_RECRUITING","2024-08-01",{"date":198,"type":40},"2024-08-06",{"date":200,"type":20},"2024-09-01",{"date":202,"type":20},"2027-03-01",{"name":204,"class":91},"Sigmund Freud PrivatUniversitat",{"id":206,"slug":207,"hasResults":11,"nctId":208,"briefTitle":209,"officialTitle":210,"acronym":211,"eligibilityCriteria":212,"healthyVolunteers":100,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":213,"targetDuration":4,"studyType":75,"phases":215,"briefSummary":216,"conditions":217,"keywords":220,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":48},"100390733","management-of-the-fresh-extraction-socket-in-the-aesthetic-area-100390733","NCT04367766","Management of the Fresh Extraction Socket in the Aesthetic Area","Management of the Fresh Extraction Socket in the Aesthetic Area: Alveolar Ridge Preservation vs Immediate Implant Placement vs Delayed Implant Placement","IIP\u002FARP\u002FSH","Inclusion Criteria:\n\n* single tooth extraction in the anterior region of the dentition (including premolars) to be extracted\n* smoking no more than 10 cigarettes\u002Fday,\n* periodontal health (BoP \\\u003C 10%) and good plaque control (\\\u003C 20%)\n* absence of symptomatic periapical radiolucencies, acute abscesses at the site of extraction,\n* extraction sites with less than 30% loss of one or more walls\n* adequate quantity and quality of native bone to achieve primary stability\n\nExclusion Criteria:\n\n* growing patients\n* patients with autoimmune disease, uncontrolled diabetes or immunocompromised\n* history of head and neck radiation for cancer treatment,\n* pregnancy",{"count":214,"type":20},60,[77],"After atraumatic tooth extraction and the assessment of the feasibility of immediate implant placement, patients will be randomly assigned to one of three treatment concepts:\n\n1. Immediate Implant Placement and Immediate Provisionalization\n2. Alveolar Ridge Preservation. After 4 months of healing an implant will be placed with simultaneous GBR and\u002For Soft Tissue Augmentation procedures, if needed.\n3. Spontaneous Healing of the socket. After 4 months of healing, an implant will be placedwith simultaneous GBR and\u002For Soft Tissue Augmentation procedures, if needed.\n\nIn all groups, four months after implant placement, a prosthesis will be delivered. From this experimental period onward, patients will be scheduled for maintenance. Clinical, radiographic and volumetric assessment will be performed by clinicians not involved in the surgery and blind with respect to treatment assignment at 1, 3 and 5 years post loading.",[218,194,24,219],"Tooth Extraction Status Nos","Soft Tissue Augmentation",[221,222,223,224,225,226,227],"Immediate implant placement","alveolar ridge preservation","delayed implant placement","PROMs","implant health","volumetric analysis","tissue augmentation","2023-12-06",{"date":230,"type":40},"2023-12-12",{"date":232,"type":40},"2023-09-27",{"date":234,"type":20},"2026-08",{"name":236,"class":237},"Centro Specialistico Odontoiatrico, Rome","NETWORK"]