[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bone-healing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bone-healing":23},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,35,62,87,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":24,"whyStopped":4,"lastUpdateSubmitDate":25,"lastUpdatePostDateStruct":26,"startDateStruct":29,"completionDateStruct":30,"leadSponsor":32,"locationsCount":4},"100631803","ultrasound-monitoring-of-bone-healing-in-ilizarov-bone-transport-100631803",false,"NCT07505433","Ultrasound Monitoring of Bone Healing in Ilizarov Bone Transport","The Role of Ultrasound in Assessment of the Bony Union in Bone Transport by Ilizarov Frame","Inclusion Criteria:\n\n* Patients who will have Ilizarov bone transport,bone lengthening or corrective osteotomy\n\nExclusion Criteria:\n\n* Otherwise bone transport,bone lengthening or corrective osteotomy","ALL",{"count":18,"type":19},56,"ESTIMATED","OBSERVATIONAL","This prospective study evaluates the role of ultrasound in assessing bony union during Ilizarov bone transport. Ultrasound findings will be compared with radiographic and clinical outcomes to determine its accuracy in detecting early bone healing and predicting mechanical stability. The study aims to establish ultrasound as a reliable, radiation-free tool to guide safe frame dynamization and removal.",[23],"Bone Healing","NOT_YET_RECRUITING","2026-03-26",{"date":27,"type":28},"2026-04-01","ACTUAL",{"date":27,"type":19},{"date":31,"type":19},"2028-12-01",{"name":33,"class":34},"Assiut University","OTHER",{"id":36,"slug":37,"hasResults":11,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":4,"eligibilityCriteria":40,"healthyVolunteers":41,"sex":16,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":46,"conditions":47,"keywords":4,"overallStatus":24,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":61},"100621558","wound-healing-following-extraction-and-ridge-preservation-in-smokers-and-non-smokers-100621558","NCT07372183","Wound Healing Following Extraction and Ridge Preservation in Smokers and Non-smokers","Inclusion Criteria:\n\n* Adult patients (18-75 years)\n* Good general health (controlled conditions)\n* Smokers (≥10 cigarettes\u002Fday for ≥5 years) and never smokers. Confirmation of smoking status will be done via use of a smokerlyzer. The cut-off point for distinguishing smokers from non-smokers is 8 carbon monoxide parts per million (ppm).\n* Periodontal status: periodontal health, gingivitis on intact or reduced periodontium, treated periodontitis\n* Intact post-extraction bony walls or less than 50% bone dehiscence\n* Distance at least 8 mm of vertical bone height between bone crest and anatomical structures (i.e. sinus floor, inferior alveolar nerve (IAN) canal, mental foramen)\n* Extracted tooth root in the same three-dimensional position as the future implant placement so that the bone core biopsy can be taken from a site totally within the confines of the former tooth socket without inclusion of surrounding native alveolar bone\n* Scheduled for single tooth extraction with bone graft placement and membrane\n\nExclusion Criteria:\n\n* Uncontrolled periodontal disease\n* Uncontrolled systemic disease\n* Pregnancy\n* Use of therapy and\u002For medication that impairs wound healing (e.g., bisphosphonates, steroids, chemotherapy, radiotherapy etc.)",true,"18 Years","75 Years",{"count":45,"type":19},12,"The goal of this study is to evaluate bone wound healing following extraction and alveolar ridge preservation (bone graft and membrane) clinically, histologically and in relation to gene expression in smokers and non-smokers. Data from a small group of participants will be analyzed after age-matched subjects undergo extraction and alveolar ridge preservation prior to implant placement. The data obtained in this pilot study will be used to plan a full-fledged study involving a larger number of smoking and non-smoking participants to compare the two groups.",[48,49,50,23,51],"Smoking, Cigarette","Alveolar Bone Grafting","Wound Healing","Tooth Extraction Site Healing","2026-01-20",{"date":54,"type":28},"2026-01-28",{"date":56,"type":19},"2026-01-25",{"date":58,"type":19},"2028-10-01",{"name":60,"class":34},"Marquette University",1,{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":4,"eligibilityCriteria":67,"healthyVolunteers":41,"sex":16,"minAge":42,"maxAge":4,"enrollmentInfo":68,"targetDuration":4,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":4,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":61},"100607622","effects-of-low-level-laser-therapy-on-soft-and-hard-tissue-healing-after-impacted-mandibular-third-molar-extraction-100607622","NCT07190950","Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction","Inclusion Criteria:\n\n* Healthy patients (at least 18 years of age) have both jaws lower impacted third molars indicated to be extracted. Both teeth are the same of\n\nExclusion Criteria:\n\n\\-",{"count":69,"type":19},22,"INTERVENTIONAL",[72],"NA","Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure. During the surgery, dental surgeon must reflect a full-thickness flap, remove bone to expose the tooth, section and deliver the tooth. As a result, after surgery, patients often experience many complications, from swelling, pain, jaw tightness, etc. to alveolar bone loss, periodontal problems distal to the second molar, etc.\n\nTherefore, clinicians are always looking for additional therapies to minimize complications, helping patients have a more comfortable experience after wisdom tooth surgery.\n\nTo date, placing grafting materials such as bone or other biological materials (growth factors, platelet-rich plasma, platelet-rich fibrin) into the tooth socket has been shown to be able to preserve the alveolar crest after extraction. However, these materials require preparation time, are costly, and have the risk of infection related to bone grafts.\n\nMeanwhile, low-level laser therapy (LLLT) is known as a safe, non-invasive therapy that can affect cell metabolism without causing tissue damage. This therapy has been widely applied in many fields of medicine in general and in dentistry in particular. Low-level lasers have been studied to help reduce swelling, pain, and jaw tightness after impacted lower wisdom teeth surgery. In vitro or in vivo studies evaluating the healing effect of low-level lasers have given very positive results. However, there is still a lack of scientific evidence to prove the healing effect of low-level lasers on human tooth extraction sockets.\n\nThe study we conducted is a scientific study, in the field of Dentistry. This study aimed to evaluate the effectiveness of low-level laser on soft tissue and bone healing after surgical extraction of impacted lower third molars in a group of Vietnamese population.",[75,76,23],"Third Molars Extraction","Low Level Laser Therapy","RECRUITING","2025-11-26",{"date":80,"type":28},"2025-11-28",{"date":82,"type":28},"2024-08-30",{"date":84,"type":19},"2025-12-31",{"name":86,"class":34},"University of Medicine and Pharmacy at Ho Chi Minh City",{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":41,"sex":16,"minAge":42,"maxAge":43,"enrollmentInfo":93,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":95,"conditions":96,"keywords":4,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":61},"100564116","determinants-of-bone-dimensional-changes-after-extraction-and-alveolar-ridge-preservation-100564116","NCT06624982","Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation","Inclusion Criteria:\n\n* Adult patients (18-75 years)\n* Good general health (controlled conditions)\n* Controlled periodontal disease\n* Scheduled for single tooth extraction with bone graft placement and resorbable membrane\n* Tooth to be extracted must have adjacent teeth\n* Socket wall integrity\n\nExclusion Criteria:\n\n* Smoking\n* Pregnancy\n* Active periodontal disease\n* Systemic conditions that affect healing\n* Lack of socket wall integrity (bone loss ≥50 %) prior to extraction, teeth with severe infection requiring pre-extraction antibiotic treatment to control infection), and contraindications for tooth extraction.",{"count":94,"type":19},160,"The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width condition (expansion or no change) is a determinant of buccolingual ridge width and height changes 4 months following extraction and ridge preservation.",[49,23,51,50],"2025-11-13",{"date":99,"type":28},"2025-11-17",{"date":101,"type":28},"2025-10-08",{"date":103,"type":19},"2027-10-01",{"name":60,"class":34},{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":41,"sex":16,"minAge":42,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":70,"phases":115,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":61},"100570784","isq-differences-between-different-implants-in-post-extraction-sockets-100570784","NCT06711744","ISQ Differences Between Different Implants in Post-extraction Sockets","Effect of Time and Local Factors on Hydrophilic Tissue Level Implants in Post-extraction Sites: a RCT","Inclusion Criteria:\n\n* Patients (at least 18 years old) presenting with failing tooth.\n* no recession of gingival contour of tooth to be extracted\n* no periodontal bone loss of neighboring teeth\n* no implants in neighboring teeth\n* class I extraction socket (intact buccal wall)\n* atraumatic extraction of the tooth with intact socket walls remaining.\n\nExclusion Criteria:\n\n* deep bite (severe II class)\n* systemic disease (diabetes, osteoporosis)\n* heavy smokers (more than 10 cigarettes\u002Fday)","99 Years",{"count":114,"type":19},30,[72],"Two different implants will be used in post-extraction sockets and ISQ will be recorded monthly from insertion moment to 12 months of follow up to understand if ISQ can be affected by implant macro design",[23,118],"Implant Stability","2025-03-24",{"date":121,"type":28},"2025-03-28",{"date":123,"type":28},"2025-01-31",{"date":125,"type":19},"2027-02-28",{"name":127,"class":34},"University of Rome Tor Vergata"]