[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bone-resorption\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bone-resorption":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,42,74,102,128,155,185,211,240,261],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100592936","the-effect-of-ipd-on-lateral-bone-augmentation-100592936",false,"NCT06999915","The Effect of IPD on Lateral Bone Augmentation","Influence of Individual Phenotypical Dimension (IPD) on Hard Tissue Stability Following Lateral Bone Augmentation: a Two-centre Clinical Study","Inclusion Criteria:\n\n* Adult (\\>18 years old) patients\n* Good medical and psychological health\n* Engaged patients presenting with a Full Mouth Plaque Score (FMPS) of ≤ 20% within the 6 weeks prior to enrolment\n* Need of a tooth\u002Fteeth replacement in the incisor, canine or premolar maxillary region that could be provided with an implant-supported fixed prosthesis\n* A relatively symmetrical maxillary arch\n* A nearly intact contra-lateral alveolar ridge\n* At least one neighbouring natural tooth present with healthy periodontal conditions\n* After implant placement, presence of a buccal bone dehiscence\u002F fenestration or buccal bone plate thickness of ≤ 1.5 mm requiring GBR (Monje et al., 2022; Jensen et al.,2023, Group 1 ITI Consensus Report).\n* At least 4 weeks of post-extraction socket healing and no ridge preservation prior to implant placement.\n* No acute infection at the site; adequate availability of bone apical and palatal to obtain implant primary stability\n* A functional occlusion with a minimum of 4 occlusal units (i.e., pairs of occluding posterior teeth)\n* Willingness to read and sign a copy of the Informed Consent Form (ICF) after reading the Patient Information Sheet (PIS), and after the nature of the study has been fully explained and potential questions fully answered.\n\nExclusion Criteria:\n\n* Any known systemic disease severely affecting bone metabolism (e.g., Cushing's syndrome, Crohn's disease, rheumatoid arthritis, osteoporosis or diabetes type I and uncontrolled diabetes type II).\n* Self-reported HIV or other severe immunosuppression.\n* Self-reported alcoholism or chronic drug abuse.\n* Heavy smokers ( \\> 10 cigarettes\u002Fday)\n* Patients reporting use of vape\u002Fe-cigarettes\n* Self-reported pregnancy or lactation\n* Chronic treatment (i.e., 2 weeks or more) with any medication known to affect oral status or bone metabolism (e.g., bisphosphonates, hormone replacement therapy, immunosuppressants) within 1 month before baseline visit.\n* Chronic treatment with anticoagulants (including Aspirin), corticosteroids, immunosuppressants or other medications that may influence blood coagulation\u002Fcount.\n* Untreated caries lesions in neighbouring teeth and untreated\u002Funcontrolled periodontal disease; If patients require periodontal treatment (non-surgical and\u002For surgical), this will be arranged outside the study protocol and completed prior to enrolment;\n* Physical handicaps that would interfere with the ability to perform adequate oral hygiene in the area of implant placement.\n* Patients requiring maxillary sinus lift surgery before implant placement or presenting bone dimensions (at any time point of the study) that do not allow implant placement or there is no clinical indication to perform study procedures (i.e. bone augmentation, implant placement).\n* Patients not willing to receive animal-derived biomaterials for GBR.\n* Patients suffering from a known psychological disorder or with limited mental capacity or language skills such that study information could not be understood, informed consent could not be obtained, or simple instructions could not be followed.\n* Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with trial participation or may interfere with the interpretation of trial results and, in the judgement of the investigator, would make the subject inappropriate for entry into this trial.","ALL","18 Years",{"count":19,"type":20},28,"ESTIMATED","INTERVENTIONAL",[23],"NA","Guided Bone Regeneration (GBR) is a widely used technique during dental implant surgery to help rebuild bone around the implant and improve its long-term appearance and stability. This study investigates whether the amount of bone that regrows depends on a person's original bone shape, known as the Individual Phenotypical Dimension (IPD). The aim is to compare the bone stability and overall results between two approaches: adding bone only up to the original bone line (IPD) or adding bone beyond it (over-contour augmentation). Over the course of a year, the study will assess not only bone and soft tissue healing, but also gum blood flow, implant success, and patient satisfaction.\n\nThere will be two treatment groups in this study - one group will receive bone grafting just up to their natural bone shape, while the other group will receive a slightly larger graft that extends about 3 mm beyond it. Throughout the study CBCT scans will be taken to assess bone changes around the implant area in order to measure how the bone shape and thickness change over time after surgery.",[26,27,28],"Guided Bone Regeneration","Bone Resorption","Diagnostic Imaging","NOT_YET_RECRUITING","2026-05-06",{"date":32,"type":33},"2026-05-07","ACTUAL",{"date":35,"type":20},"2026-06",{"date":37,"type":20},"2029-06",{"name":39,"class":40},"Queen Mary University of London","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":61,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":41},"100632963","socket-shield-technique-with-cgf-and-xenograft-for-immediate-implants-100632963","NCT07520513","Socket Shield Technique With CGF and Xenograft for Immediate Implants","Clinical and Radiographic Evaluation of Bone Grafting Using Concentrated Growth Factors and Xenograft With Simultaneous Immediate Implant Placement in Socket Shield Technique","CGF","Inclusion criteria:\n\n* Age ≥18 years old. (Younis, W., \\& El-Rashidy, A. 2020).\n* Both male and female patients.\n* Maxillary, anterior and premolar segments.\n\nExclusion Criteria:\n\n* A medical history that contraindicates oral surgical treatment such as (uncontrolled\u002Funtreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and\u002For intravenous bisphosphonates).\n* Presence of active or untreated periodontal disease.\n* Vertical root fractures involving the buccal aspect.\n* Tooth \u002Fteeth with horizontal fractures below bone level.\n* Tooth \u002Fteeth with external or internal resorption.\n* Patients with destructive oral habits such as smoking, chewing tobacco, bruxism, etcetera.",{"count":51,"type":20},7,[23],"This prospective case series aims to evaluate the clinical and radiographic outcomes of immediate implant placement using the socket shield technique combined with concentrated growth factors (CGF) and xenograft in the esthetic zone. The study will assess crestal bone level changes and implant stability over a 6-month follow-up period.",[55,56,27,57,58,59,60],"Alveolar Bone Loss","Socket Shield Technique","Immediate Dental Implant Placement","Concentrated Growth Factors","Xenograft","Alveolar Bone Preservation",[62,63,64,59],"immediate implants","socket shield technique","Concentrated growth factor","2026-04-08",{"date":67,"type":33},"2026-04-13",{"date":69,"type":20},"2026-04-05",{"date":71,"type":20},"2026-12-30",{"name":73,"class":40},"Cairo University",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":85,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":41},"100568289","surgical-treatment-of-peri-implantitis-with-adjunctive-application-of-platelet-rich-fibrin-prf-100568289","NCT06679283","Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF)","Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF) Compared With Open Flap Debridement (OFD) Alone: A 12-month Randomised Clinical Trial","PRF","Inclusion Criteria:\n\n1. One or more peri-implant sites with PPD ≧ 5 mm combined with BOP\u002Fsuppuration and\n2. Peri-implant marginal bone loss, defined as a crater like defect ≧ 3 mm as assessed from intraoral radiographs\n3. Good oral hygiene i.e. a plaque index \\\u003C20%\n4. Written informed consent\n\nExclusion Criteria:\n\n1. History of chronic inflammatory disease\n2. Severe systemic diseases\n3. Medically confirmed diagnosis of diabetes mellitus\n4. Anti-inflammatory prescription including prednisone\n5. Smoking \\> 5 cigarettes\n6. Pregnant or lactating women\n7. \\\u003C 18 years of age",true,{"count":84,"type":20},40,[23],"Platelet-rich fibrin (PRF) is a second-generation platelet concentrate used for tissue and bone regeneration. PRF releases growth factors such as TGF-β, PDGF, VEGF, IGF, and FGF, which are known to promote wound healing and bone regeneration. Thus, PRF may offer a promising therapeutic approach for peri-implantitis treatment. Numerous studies have reported beneficial effects of PRF on bone regeneration, bone augmentation, soft tissue healing, and ridge preservation. In infrabony periodontal defects, PRF has shown significant improvements in pocket depth reduction, clinical attachment level (CAL) gain, and bone fill.\n\nHowever, a recent systematic review highlighted that evidence supporting PRF use in peri-implantitis remains limited, primarily due to a lack of adequately designed studies. Therefore, the aim of this project is to investigate whether PRF enhances regeneration in peri-implantitis defects. Specifically, it will assess whether surgical debridement of peri-implantitis defects-including electrochemical detoxification of implant surfaces using GalvoSurge-combined with PRF clot and membrane placement, improves treatment outcomes compared to surgical debridement and detoxification using GalvoSurge alone.\n\nFor this purpose, implants with peri-implantitis defects of comparable size will be randomly assigned to either the test or control group. After 12 months, implants will be clinically evaluated for radiographic defect fill, reduction in probing pocket depth (PPD), and bleeding on probing (BOP). The objective of this project is to verify, both radiographically and clinically, whether adjunctive PRF application enhances tissue regeneration and healing of peri-implantitis defects compared to open flap debridement (OFD) alone.",[88,27,89],"Peri-Implantitis","Platelet-Rich Fibrin",[91],"platelet rich fibrin, peri-implantitis","RECRUITING","2026-03-24",{"date":95,"type":33},"2026-03-30",{"date":97,"type":33},"2025-02-01",{"date":99,"type":20},"2027-12-31",{"name":101,"class":40},"University of Bern",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":82,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":21,"phases":112,"briefSummary":113,"conditions":114,"keywords":115,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":41},"100579145","comparison-of-three-transmucosal-augmentation-techniques-in-immediate-implant-placement-100579145","NCT06820489","Comparison of Three Transmucosal Augmentation Techniques in Immediate Implant Placement","A Three-arm Randomized Controlled Trial Comparing Transmucosal Augmentation Techniques in Immediate Implant Placement","Inclusion Criteria:\n\n* At least 20 years old\n* Good oral hygiene defined as full-mouth plaque score ≤ 25%\n* Presence of an incisor, cuspid or premolar in the maxilla that needs to be extracted for any reason with at least one neighboring tooth present\n* At least 3 mm bone available at the apical or palatal aspect of the alveolus as assessed on CBCT to ensure primary implant stability\n* Intact buccal bone wall (type I) or limited buccal bone dehiscence (type IIa or IIb) at the time of extraction\n* Written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy\n* Systemic diseases\n* Smoking; suppuration\n* \\> 1 mm gingival asymmetry between the failing and contralateral tooth\n* Untreated periodontal disease\n* Untreated caries lesions.","20 Years",{"count":111,"type":20},54,[23],"Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT). Prior to surgery, a small- field low-dose cone beam computed tomography (CBCT) is taken to verify the integrity of the facial bone wall and an adequate amount of apical and palatal bone availability for implant anchorage. 54 patients will be randomly assigned to either conventional connective tissue graft (C-CTG), scarf tissue graft (S-CTG) or dual zonde conept (DZ). Sealed envelopes are prepared for that purpose, of which 18 are internally labeled as C-CTG, 18 as S-CTG and 18 as DZ. Following IIP, a sealed envelope will be opened to reveal the treatment concept.\n\nSuccessful regeneration (primary outcome) is achieved when the combination of socket grafting and transmucosal augmentation (C-CTG or S-CTG or DZ) would be able to counteract any buccal soft tissue loss at level -1 mm. It is assessed on the basis of superimposed CBCTs taken pre-operatively and at one-year follow-up. Secondary outcomes include: horizontal buccal bone loss, vertical buccal bone loss, increase in buccal soft tissue thickness, patient-reported outcomes, plaque, bleeding on probing, probing depth, marginal bone loss, change in buccal soft tissue profile, midfacial soft tissue level, mesial and distal papilla level, Pink Esthetic Score.",[27],[116,117,118],"Dental Implant, Single-Tooth","Immediate","Connective tissue graft","2026-01-07",{"date":121,"type":33},"2026-01-09",{"date":123,"type":33},"2025-04-01",{"date":125,"type":20},"2031-11-01",{"name":127,"class":40},"University Ghent",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":82,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":21,"phases":137,"briefSummary":138,"conditions":139,"keywords":140,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":154},"100599147","state-of-the-art-immediate-implant-placement-in-the-premaxilla-100599147","NCT07080710","State of the Art Immediate Implant Placement in the Premaxilla","A Clinical Study on Immediate Implant Placement in the Premaxilla With Flapless Guided Surgery, Hard and Soft Tissue Augmentation and Immediate Provisionalization","Inclusion Criteria:\n\n* At least 20 years old\n* Good oral hygiene defined as full-mouth plaque score ≤ 25%\n* Presence of one or more incisors, cuspids or premolars in the maxilla that need to be extracted for any reason with at least one neighboring tooth present\n* At least 3 mm bone available at the apical or palatal aspect of the alveoli as assessed on a three-dimensional radiograph to ensure primary implant stability\n* Written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy (will be explicitly asked)\n* Systemic diseases\n* Smoking; suppuration\n* \\> 1 mm gingival asymmetry between the failing teeth and contralateral teeth\n* Failing teeth outside the bone envelop as assessed on a three-dimensional radiograph\n* Untreated periodontal disease; untreated caries lesions.",{"count":136,"type":20},50,[23],"The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns. It will also learn about the safety and esthetic results of this treatment approach.\n\nThe main questions it aims to answer are:\n\nPrimary:\n\nHow much buccal bone thickness remains one year after implant placement 1mm below the implant shoulder?\n\nSecondary:\n\n* How do patients rate pain, healing, and esthetics after treatment?\n* Are there any complications over the course of five years?\n* How much buccal bone thickness remains one year after implant placement 3mm and 5mm below the implant shoulder?\n* Marginal bone loss at one-year and five-year follow-up?\n* Peri-implant health at one-year and five-year follow-up?\n* Soft tissue changes at one-year and five-year follow-up?\n\nResearchers will compare treatment results in patients with intact bone sockets to those with damaged (non-intact) sockets.\n\nParticipants will:\n\n* Receive a dental implant and temporary crown on the same day as the tooth extraction\n* Undergo guided, flapless surgery with bone and soft tissue grafting\n* Take antibiotics and anti-inflammatories for 4 days after surgery\n* Visit the clinic at 1 week, 3 months, 1 year, and 5 years for follow-up exams\n* Have X-rays, digital scans, and photos taken to measure bone and soft tissue changes\n* Answer questions about pain and esthetic satisfaction",[27],[141,117,142,143,144,145],"dental implant, single-tooth","connective tissue graft","socket grafting","intact alveolus","non-intact alveolus","2025-11-14",{"date":148,"type":33},"2025-11-18",{"date":150,"type":33},"2025-07-01",{"date":152,"type":20},"2032-02-01",{"name":127,"class":40},2,{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":162,"targetDuration":4,"studyType":164,"phases":4,"briefSummary":165,"conditions":166,"keywords":167,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":177,"completionDateStruct":179,"leadSponsor":181,"locationsCount":184},"100544857","bone-substitutes-outcomes---post-market-follow-up-100544857","NCT06374342","Bone Substitutes Outcomes - Post Market Follow-up","Safety and Clinical Performance Assessment of Bone Substitutes Used for Bone Voids Filling - A Post-Market Clinical Follow-Up","Inclusion Criteria:\n\n* Be 18 years or older.\n* Be willing to sign an informed consent approved by IRB or EC (where applicable) or not being opposed to the use of their clinical data in the study (France) and\n\n  o For prospective inclusion:\n* Be considered for a surgery where bone filling with one of the TEKNIMED bone substitutes comprised in this study is needed and intended to be used according to the IFU.\n\n  o For retrospective inclusion:\n* Have undergone a surgery with a TEKNIMED bone substitute used according to the IFU, between the 1st January 2015 and the date of the site initiation visit\n* Be informed of the study and not being opposed to the use of their clinical data in the study (France) or be willing to sign an informed consent (where applicable) during the first follow-up visit following the site initiation.\n\nExclusion Criteria:\n\nPatients presenting one of the following conditions will not be included:\n\n* Under trusteeship or guardianship\n* Pregnancy or breast-feeding women\n\nAccording to contraindications per IFU:\n\n* Procedures other than those stated in the INDICATIONS section\n* Patients susceptible to allergic reactions to the product components.\n\nCERAFORM®, TRIHA+®:\n\n\\- Treatment of large bone defects which could impact the stability of bone structure without implementing a mechanical stabilisation system (such as plate(s), screw(s), nail(s), cage(s))\n\nNANOGEL®:\n\n* Use in vertebroplasty procedures\n* Subcutaneous use",{"count":163,"type":20},425,"OBSERVATIONAL","A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Bone Substitute range of products: CERAFORM, TRIHA+, NANOGEL, and all their private labels.\n\nTEKNIMED bone substitutes are legacy products, some marketed for more than 20 years. Their performance and safety have already been demonstrated by Post-Market Surveillance and previous clinical studies. The current Post-Market Clinical Follow-Up study aims to confirm these claims by collecting data in a \"real-life\" setting.\n\nThe study is a retrospective and prospective global, single arm, non-controlled, multicentric, prospective observational study. Patients will be followed as per local standard medical care of the sites.",[27],[168,169,170,171,172,173],"Bone substitutes","Gel","Hydroxyapatite","Tricalcium phosphate","Calcium phosphate","Ceramics","2025-09-02",{"date":176,"type":33},"2025-09-09",{"date":178,"type":33},"2021-09-16",{"date":180,"type":20},"2032-09-30",{"name":182,"class":183},"Teknimed","INDUSTRY",6,{"id":186,"slug":187,"hasResults":11,"nctId":188,"briefTitle":189,"officialTitle":190,"acronym":4,"eligibilityCriteria":191,"healthyVolunteers":82,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":192,"targetDuration":4,"studyType":21,"phases":194,"briefSummary":195,"conditions":196,"keywords":198,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":202,"lastUpdatePostDateStruct":203,"startDateStruct":205,"completionDateStruct":207,"leadSponsor":209,"locationsCount":154},"100574851","randomized-clinical-study-comparing-two-guided-surgery-techniques-for-free-end-implant-placement-100574851","NCT06764654","Randomized Clinical Study Comparing Two Guided Surgery Techniques for Free-end Implant Placement","Randomized Clinical Study Comparing Two Guided Surgery Techniques for Free-end Implant Placement: A Multicenter Study","Inclusion Criteria:\n\n* Patients who present to one of the two participating clinics with a posterior edentulous area starting from the second premolar.\n* Patients in whom the placement of dental implants is not contraindicated.\n\nExclusion Criteria:\n\n* Patients with hypersensitivities or allergies that contraindicate the intervention.\n* Presence of orofacial neurological symptoms.\n* Patients treated with bisphosphonates.\n* Pregnant or breastfeeding women, or women undergoing contraceptive treatment.\n* Signs of infection in the surgical area.\n* Need for unconventional surgical procedures (e.g., split crest, vertical regeneration, block graft).\n* Lack of patient cooperation.",{"count":193,"type":20},20,[23],"This is a randomized multicenter clinical study that compares two static guided surgery techniques in free-end partial edentulism.\n\nThe aim is to compare the accuracy obtained between dento-osseous supported and dento-mucosal supported surgical splints to place dental implants in posterior osseous ridges.",[197,27],"Dental Implant",[199,200,201],"guided suergery","dental implant","partial edentulous","2025-07-03",{"date":204,"type":33},"2025-07-09",{"date":206,"type":33},"2025-01-01",{"date":208,"type":20},"2026-03-01",{"name":210,"class":40},"Aula Dental Avanzada",{"id":212,"slug":213,"hasResults":11,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":82,"sex":16,"minAge":17,"maxAge":218,"enrollmentInfo":219,"targetDuration":4,"studyType":21,"phases":221,"briefSummary":222,"conditions":223,"keywords":226,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":41},"100457731","pontic-shield-technique-in-alveolar-ridge-preservation-100457731","NCT05240417","\"Pontic-shield\" Technique in Alveolar Ridge Preservation","Effectiveness of \"Pontic-shield\" Technique in Alveolar Ridge Preservation: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patient from 18 to 80 years old\n* Patients who sign the informed consent\n* Need to perform extraction from second premolar to second premolar in maxilla and mandible\n\nExclusion Criteria:\n\n* Tobacco consumption (more than 10 cigarettes per day)\n* Severe systemic disease ( ASA III or IV - American Society of Anaesthesiology)\n* Drug use that could interfere with alveolar bone healing\n* Active periodontal disease\n* Acute or chronic apical pathology of the tooth","80 Years",{"count":220,"type":20},30,[23],"Alveolar bone resorption after dental extraction frequently leads to situations in which long-term function and esthetic success of rehabilitations with dental implants is a challenge. \"Pontic-shield\" has been described as an alternative technique to maintain alveolar ridge after tooth extraction.\n\nThe aim of this study is to analyze the effectiveness of \"Pontic-shield\" technique in alveolar ridge preservation comparing to fresh socket and ridge preservation using deproteinized bovine bone and a porcine collagen membrane.",[224,225,27],"Tooth Extraction Status Nos","Bone Loss",[227,228,229,230],"Tooth extraction","Alveolar ridge preservation","Partial extraction therapies","Bone resorption","2024-08-19",{"date":233,"type":33},"2024-08-20",{"date":235,"type":33},"2023-01-01",{"date":237,"type":20},"2024-12-01",{"name":239,"class":40},"Universidad Complutense de Madrid",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":82,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":247,"targetDuration":4,"studyType":21,"phases":249,"briefSummary":250,"conditions":251,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":259,"locationsCount":41},"100541768","guided-bone-regeneration-using-fixed-vs-non-fixed-resorbable-collagen-membranes-100541768","NCT06334159","Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes","Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Men and women over 18 years old or older\n2. Patients requiring Guided Bone Regeneration due to insufficient ridge width(≤5mm) to place dental implants, with sufficient vertical ridge height (≥9mm) from vital anatomical structures (the inferior alveolar nerve in the Mandible, or the sinus in the Maxilla)\n3. One or more teeth missing in posterior zone (Premolars, and Molars)\n4. Absence of active Periodontal disease\n5. Good level of oral hygiene (Plaque index \\\u003C25%)\n6. Absence of systemic diseases that could influence the outcome of the therapy (Uncontrolled diabetes, osteoporosis, bisphosphonate medications)\n7. Non smokers or light smokers (\\\u003C10 cigarettes per day)\n8. Informed consent signed\n\nExclusion Criteria:\n\n1. Patients with sufficient ridge width (\\>5 mm) and height (≥9mm) from vital anatomical structure) requiring no GBR to place dental implants\n2. Patients with severe horizontal and vertical defects requiring other surgical techniques.\n3. Long-term non-steroidal anti-inflammatory drug therapy (3months).\n4. Lactating females or currently pregnant women.\n5. Severe cognitive or psychiatric disorders.\n6. Unwillingness to return for follow-up examination.",{"count":248,"type":20},26,[23],"The aim of this clinical trial is to compare the horizontal bone gain when grafting a bone substitute with non fixed resorbable collagen membranes (control group), versus fixed resorbable collagen membranes (test group) in resorbed ridges requiring Guided Bone Regeneration (GBR) to facilitate implant placement at 6 months.",[27],"2024-03-20",{"date":254,"type":33},"2024-03-27",{"date":256,"type":33},"2020-11-05",{"date":258,"type":20},"2027-07-20",{"name":260,"class":40},"Universitat Internacional de Catalunya",{"id":262,"slug":263,"hasResults":11,"nctId":264,"briefTitle":265,"officialTitle":266,"acronym":4,"eligibilityCriteria":267,"healthyVolunteers":82,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":268,"targetDuration":4,"studyType":21,"phases":269,"briefSummary":270,"conditions":271,"keywords":272,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":276,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":41},"100480558","timing-of-soft-tissue-grafting-following-immediate-implant-placement-100480558","NCT05537545","Timing of Soft Tissue Grafting Following Immediate Implant Placement","A Randomized Controlled Trial on the Timing of Soft Tissue Grafting Following Immediate Implant Placement","Inclusion Criteria:\n\n* At least 20 years old\n* Good oral hygiene defined as full-mouth plaque score ≤ 25% (O'Leary et al. 1972)\n* Presence of an incisor, cuspid or premolar in the maxilla that needs to be extracted for any reason with at least one neighboring tooth present\n* At least 3 mm bone available at the apical or palatal aspect of the alveolus as assessed on CBCT to ensure primary implant stability\n* Intact buccal bone wall at the time of extraction\n* Written informed consent\n\nExclusion Criteria:\n\n* Pregnancy\n* Systemic diseases\n* Smoking\n* Suppuration\n* \\> 1 mm gingival asymmetry between the failing and contralateral tooth\n* Untreated periodontal disease; untreated caries lesions",{"count":84,"type":20},[23],"Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT). Prior to surgery, a small- field low-dose cone beam computed tomography (CBCT) is taken to verify the integrity of the facial bone wall and an adequate amount of apical and palatal bone availability for implant anchorage.\n\nIn all of the patients, a connective tissue graft (CTG) will be harvested and inserted into the buccal mucosa to increase soft tissue thickness around the immediately installed implant. However, included patients will be randomly allocated to either receive the CTG immediately after implant installation (Immediate soft tissue grafting, ISG = control group) or 3 months after implant installation (Delayed soft tissue grafting, DSG = test group).\n\nForty sealed envelopes are prepared for that purpose, of which 20 are internally labeled as \"DSG\" and 20 as \"ISG\". Following IIP, a sealed envelope will be opened to reveal the treatment concept In both groups, a cutting implant is installed in an optimal 3D position. Socket grafting is performed with deproteinized bovine bone mineral to limit buccal bone resorption and to optimize soft tissue stability.\n\nIn the ISG group, a pouch is made in the buccal mucosa using microsurgical instruments. Thereupon, a free gingival graft is harvested from the palatal mucosa in the premolar area and de-epithelialized to arrive at a CTG of about 1 mm thickness. Height and length are tailored to the dimensions of the site. Then, the CTG is brought into the pouch and fixed with two single sutures onto the buccal mucosa. Finally, a healing abutment is installed, which is replaced by a provisional implant crown 2 days later.\n\nIn the DSG group, implant placement, socket grafting and installation of a provisional implant crown occur as described above. In contrast, a buccal pouch is performed 3 months after implant installation. Graft harvesting, adaptation and fixation are performed as described above.\n\nA small-field low-dose CBCT is taken at the 1-year and 5-year follow-up in order to measure buccal bone resorption as compared to the baseline dimensions in designated software.",[27],[273,274,142],"dental implant, single tooth","immediate","2023-10-02",{"date":277,"type":33},"2023-10-03",{"date":279,"type":33},"2022-08-01",{"date":281,"type":20},"2028-07-01",{"name":127,"class":40}]