[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bowel-function-dissatisfaction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bowel-function-dissatisfaction":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100475658","impact-of-a-dried-vegetable-on-bowel-function-and-gut-microbiota-100475658",false,"NCT05473793","Impact of a Dried Vegetable on Bowel Function and Gut Microbiota","The Impact of a Dried Vegetable on Bowel Function and Gut Microbiota in Subjects With Bowel Function Issues","HappYFiber","Inclusion Criteria:\n\n* 20 - 80 years old\n* Unsatisfied with bowel functions (self-reported), rated on a visual analogue scale (VAS, 0-10) as less than 6\n* Four or less bowel movements per week (low stool frequency) and\u002For\n* Hard, lumpy or solid stools (Bristol stool form 1-4) during 90% of bowel movements (hard to solid consistency)\n* Able to read and understand Dutch or English\n\nExclusion Criteria:\n\n* Having a history of medical or surgical events that may significantly affect the study outcome: e.g., IBS or IBD patients and subjects with medically diagnosed constipation (i.e., constipation related to anatomic, medication-related, or readily identifiable physiological causes.)\n* Less than one bowel movement per week during the screening\n* Medical drug use:\n\n  * Antibiotic use within 3 months of the study screenings day\n  * Chronic use of antacids and PPI's\n  * Use of laxatives during the screening\n  * Chronic use of blood glucose lowering medication\n* Consumption of supplements containing fibres (other than laxatives), pro-\u002F post-\u002F synbiotics 1 month before the screening\n* Not willing to provide faecal samples\n* Unable to comply with proper study procedures\n* For women of childbearing age: current or planned pregnancy, lactation\n* Known allergic reactions to plants from the Asteraceae (Compositae) family (e.g., lettuce, daisies, sunflowers, artichokes, sage, tarragon, chamomile, chicory etc.)\n* Reported unexplained weight loss or weight gain of greater than 5 kg in the month prior to pre-study screening\n* Reported slimming or medically prescribed diet\n* Reported macrobiotic lifestyle\n* Personnel the Division of Human Nutrition \\& Health or the Laboratory of Microbiology\n* Current participation in other medical scientific research\n* Not having a general practitioner\n* Not willing to be informed about accidental discoveries in relation to the subjects health",true,"ALL","20 Years","80 Years",{"count":22,"type":23},160,"ESTIMATED","INTERVENTIONAL",[26],"NA","A randomized, placebo-controlled, parallel, double-blind trial with three intervention arms and a period of four intervention-weeks that assesses the intake of different dosages of a complex fiber product on bowel function via microbiota changes in subjects that are unsatisfied with their current bowel function.",[29],"Bowel Function Dissatisfaction",[31,32,33,34,35,36],"bowel function issues","constipation","gut microbiota","fiber intake","vegetable","intrinsic fiber","RECRUITING","2025-02-22",{"date":40,"type":41},"2025-02-25","ACTUAL",{"date":43,"type":41},"2022-08-22",{"date":45,"type":23},"2025-06",{"name":47,"class":48},"Wageningen University","OTHER"]