[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bowel-preparation-for-colonoscopy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bowel-preparation-for-colonoscopy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,69,93,119],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100053729","administration-of-a-thirst-relieve-kit-versus-placebo-in-patients-after-hospital-based-bowel-preparation-for-colonoscopy-and-assessment-of-thirst-intensity-100053729",false,"NCT07699809","Administration of a 'Thirst Relieve Kit' Versus Placebo in Patients After Hospital-based Bowel Preparation for Colonoscopy and Assessment of Thirst Intensity","Inclusion Criteria:\n\n* both sexes\n* aged 18 years or older, with clear awareness and good cooperation\n* who underwent colonoscopy with hospital bowel preparation\n\nExclusion Criteria:\n\n* any risk of oral fluid aspiration\n* swallowing disorders\n* post-operative advanced head and neck surgeries\n* advanced head and neck neoplasia, active oral diseases (oral mucosal lesions, stomatitis, among others)\n* history of gastric surgeries (gastrectomized, upper gastrointestinal tract surgeries for obesity)\n* use of GLP-1 analog medications and derivatives in the last 10 days according to hospital protocol (e.g., semaglutide, liraglutide, dulaglutide, tirzepatide...)\n* history of dementia.",true,"ALL","18 Years",{"count":19,"type":20},158,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to evaluate whether a \"thirst kit\" (lemon popsicle) is effective in reducing thirst intensity in patients undergoing hospital bowel preparation for colonoscopy. The study also aims to assess the impact of the thirst kit on associated symptoms and patient satisfaction. The main questions it aims to answer are:\n\n* Does the thirst kit reduce the intensity of thirst after bowel preparation for colonoscopy?\n* Does the thirst kit reduce symptoms such as dry mouth and dry throat?\n* How satisfied are patients when using the thirst kit compared to a placebo?\n\nResearchers will compare the thirst kit to a placebo to determine its effectiveness in managing thirst during the pre-colonoscopy period.\n\nParticipants will:\n\n* Be randomly assigned to receive either the thirst kit (lemon popsicle) or a placebo\n* Use the assigned intervention during the hospital preparation period for colonoscopy\n* Rate thirst intensity, associated symptoms, and satisfaction using numerical scales",[26,27,28],"Thirst","Bowel Preparation for Colonoscopy","Colonoscopy","RECRUITING","2026-07-07",{"date":32,"type":33},"2026-07-13","ACTUAL",{"date":35,"type":33},"2025-12-08",{"date":37,"type":20},"2026-09-01",{"name":39,"class":40},"Hospital Sirio-Libanes","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100597571","phase-4-intestinal-preparation-in-colonoscopy-lactulose-vs-sodium-phosphate-100597571","NCT07060222","Intestinal Preparation in Colonoscopy: Lactulose vs Sodium Phosphate.","Intestinal Preparation in Colonoscopy: Lactulose vs Sodium Phosphate, a Multicenter, Randomized, Double-Blind Comparative Clinical Trial.","Inclusion Criteria:\n\n* Indication for Scheduled Colonoscopy: Participants must have a valid clinical indication for undergoing a scheduled colonoscopy, such as part of a colorectal cancer screening program, evaluation of gastrointestinal symptoms, or follow-up of previously diagnosed colorectal conditions.\n* Ability to Provide Informed Consent: Participants must have the physical and mental capacity to understand the nature of the study and voluntarily provide informed consent to participate.\n\nExclusion Criteria:\n\n* History of Intestinal Obstruction: Participants with a known or suspected history of intestinal obstruction will be excluded due to the potential risks associated with the administration of bowel preparation agents.\n* Known Intolerance to Lactulose or Sodium Phosphate: Participants with a known intolerance to lactulose or sodium phosphate will be excluded due to the risk of severe adverse reactions.\n* Pregnancy and Lactation: Pregnant or breastfeeding women will be excluded due to the lack of safety data on bowel preparation agents in this population.\n* Interfering Clinical Conditions (Comorbidities): Participants with medical conditions that could interfere with study participation or affect the interpretation of results will be excluded, such as decompensated heart failure, chronic renal or liver disease, and a history of colonic resection.",{"count":50,"type":20},300,[52],"PHASE4","To compare intestinal preparation with Lactulose vs. Sodium Phosphate as the better agent for performing high-quality colonoscopies at the Civil Hospital Fray Antonio Alcalde and the Civil Hospital Juan I. Menchaca, both in Guadalajara, Mexico; as well as Hospital Santo Tomás in Panama City, Panama; and Hospital Gustavo Nelson Collado Ríos in Chitré, Panama; during the period from April 1, 2025, to November 30, 2025. The comparison will focus on colonoscopy quality, patient tolerance, satisfaction, and electrolyte changes, using the agents orally as part of the bowel preparation prior to the colonoscopy procedure.",[27],[56,28,57,58],"lactulose","sodium phosphate","bowel preparation","2026-04-30",{"date":61,"type":33},"2026-05-05",{"date":63,"type":33},"2025-09-20",{"date":65,"type":20},"2026-12-31",{"name":67,"class":40},"Hospital Civil de Guadalajara",4,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":78,"conditions":79,"keywords":80,"overallStatus":83,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":4},"100618905","exploring-the-clinical-value-of-an-ai-assisted-patient-self-assessment-app-for-bowel-preparation-a-multicenter-study-100618905","NCT07337694","Exploring the Clinical Value of an AI-Assisted Patient Self-Assessment App for Bowel Preparation: A Multicenter Study","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Undergoing colonoscopy at a participating site\n3. Able to defecate in a toilet (or in a setting where stool characteristics can be observed) after taking the bowel-prep solution\n4. Proficient in using a smartphone\n5. Willing to participate voluntarily\n\nExclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) class III or IV;\n\n  * Gastric-outlet or intestinal obstruction; ③ Active gastrointestinal bleeding; ④ Enterostomy (colostomy\u002Fileostomy); ⑤ Status post total colectomy.",{"count":76,"type":20},524,[23],"The quality of bowel preparation hinges on how well patients follow the prep-drug regimen, so intensive education is essential. Phone calls, texts, short videos, and mini-programs have all been shown to boost compliance and improve prep quality. Still, we also need a way to spot-early-those patients who are likely to prep poorly so we can step in with a rescue plan.\n\nIn our pilot work the investigators built an AI-assisted mini-program that lets patients photograph their effluent and get an instant quality read-out. The single-center RCT showed excellent performance. Because these findings came from one center, the investigators are now launching a multicenter study to test the tool more broadly. Patients will use the AI mini-program at home; if the algorithm predicts inadequate prep it will prompt them to come in early or alert staff so the investigators can initiate a rescue protocol and, ultimately, improve bowel-cleansing quality.",[27,28],[81,28,82],"Bowel preparation","Artificial intelligence","NOT_YET_RECRUITING","2026-01-16",{"date":86,"type":33},"2026-01-21",{"date":88,"type":20},"2026-01-01",{"date":90,"type":20},"2027-12-31",{"name":92,"class":40},"Sixth Affiliated Hospital, Sun Yat-sen University",{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":100,"targetDuration":4,"studyType":21,"phases":102,"briefSummary":103,"conditions":104,"keywords":106,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":118},"100602733","phase-4-the-impact-of-glp-medication-on-colonoscopy-bowel-preparation-quality-100602733","NCT07127354","The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality","The Impact of GLP-1 Agonist and GIP Agonist on Bowel Preparation Quality: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patient (Age 18 years or older)\n* Patient scheduled for outpatient screening, surveillance, or diagnostic colonoscopy\n* Using a GLP-1 or GIP agonist at a stable dose for at least one month\n\nExclusion Criteria:\n\n* Unable to provide informed consent, e.g., dementia\n* Patient refuses the USMSTF recommended bowel cleansing regimen for patients with diabetes or obesity (split-dose 4 liters polyethylene glycol + 15 mg bisacodyl the afternoon before; low residue diet 3 days before colonoscopy; clear liquid diet the day before colonoscopy)\n* Risk factors for inadequate bowel preparation besides diabetes and obesity with a likelihood ratio of 1.6 or greater:\n\n  1. Cirrhosis\n  2. Parkinson's disease\n  3. Dementia\n  4. Tricyclic antidepressant use\n  5. Opioid use\n  6. Gastroparesis\\* or suspected gastric outlet obstruction on pre-procedure imaging (\\*defined based on a documented 4-hour solid phase gastric emptying study or prior history of retained gastric contents during upper endoscopy)\n  7. Previous colorectal surgery\n  8. Prior history of inadequate bowel preparation",{"count":101,"type":20},132,[52],"The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies. The main questions it aims to answer are:\n\n* Does GLP-1 and GIP agonist increase the rate of inadequate bowel preparation?\n* Does the quality of bowel preparation differ in patients who hold vs. those who continue a single dose of their GLP-1 or GIP agonist medication?\n* Are there any differences in the rates of complications gastric aspiration in patients who hold vs. continue a single dose of their GLP-1 or GIP agonist medication?",[105,27],"GLP - 1",[107,108],"GLP-1","Bowel preparation for colonoscopy","2025-12-02",{"date":111,"type":33},"2025-12-04",{"date":113,"type":33},"2025-08-01",{"date":115,"type":20},"2026-08",{"name":117,"class":40},"The Cleveland Clinic",3,{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":4,"eligibilityCriteria":125,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":126,"enrollmentInfo":127,"targetDuration":4,"studyType":21,"phases":129,"briefSummary":130,"conditions":131,"keywords":132,"overallStatus":83,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":4},"100572097","efficacy-safety-and-tolerability-of-magnesium-sulfate-with-low-volume-polyethylene-glycol-for-colonoscopy-cleansing-100572097","NCT06728839","Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing","Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Bowel Preparation Before Colonoscopy: A Multicentre, Randomized, Controlled Trial","Inclusion Criteria:\n\n* 18-75 years old, male or female\n* To undergo screening, surveillance and diagnostic colonoscopy\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Subjects with therapeutic colonoscopy for colorectal polyps\n* Subjects with confirmed or suspected gastrointestinal obstruction, gastric retention, gastroparesis, gastric emptying disorder, or acute gastrointestinal bleeding\n* Subjects with confirmed or suspected colorectal cancer, inflammatory bowel disease, toxic colitis, or toxic megacolon\n* Subjects with renal or liver dysfunction, congestive heart failure or rhabdomyolysis\n* Subjects with ascites, suspected electrolyte abnormalities, or uncorrected dehydration\n* Subjects with constipation (\\\u003C3 times a week, difficult defecation, dry stool, less amount)\n* Subjects with serious cardiac and cerebrovascular diseases,suffering from metabolic disease or endocrine disease\n* Subjects who had previously undergone colorectal resection\n* Women with positive pregnancy tests or pregnancy plans, and women in lactation or allergic to the investigational drugs and their ingredients\n* Subjects who are participating in other clinical trials or receiving special drugs\n* Subjects with any other conditions that the investigator considered inappropriate for inclusion","75 Years",{"count":128,"type":20},1329,[23],"Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy. Magnesium sulfate combined with polyethylene glycol is less used in the world. This multicenter, randomized, controlled trial is aimed at to evaluate the efficacy and safety of magnesium sulfate combined with low-volume polyethylene glycol for preoperative bowel preparation for colonoscopy.",[27],[133,134,58,135],"Magnesium sulfate","colonoscopy","adenoma detection rate","2024-12-08",{"date":138,"type":33},"2024-12-11",{"date":140,"type":20},"2024-12-09",{"date":142,"type":20},"2025-08-31",{"name":144,"class":40},"Changhai Hospital"]