[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bpsd\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bpsd":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100638866","effects-of-binaural-beats-and-spatialized-music-on-behavioural-and-psychological-symptoms-of-dementia-in-assisted-living-facility-residents-100638866",false,"NCT07626944","Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents","Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents: A Randomized Controlled Pilot Protocol","Inclusion Criteria:\n\n* (1) age 55-95 years; (2) the subject and\u002For his\u002Fher legal guardian have signed written informed consent; (3) the subject is able to complete the entire trial period; and (4) a minimum of fifty percent of the subjects will have a diagnosis of a dementia condition with a moderate to severe progression.\n\nExclusion Criteria:\n\n* (1) profound hearing loss or impairment; (2) history of seizures, epilepsy (especially sound-induced epilepsy), claustrophobia, or other conditions that put the subject at risk during the trial; (3) physical or mental conditions that may result in inability to complete and\u002For affect the efficacy of assessment.","ALL","55 Years","95 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to investigate the effects of Binaural Beat Music (BBM; personalized music playlist with binaural beats), Spatialized Music (SM; personalized and spatialized music playlist), their combination, and possible interaction on older adults in an assisted living community who are either living with a dementia diagnosis or are experiencing typical age-related changes. The control condition is a personalized music playlist without binaural beats and spatialization. It is hypothesized that BBM, SM, and their combination each improve aspects of BPSD compared to controls over a two-week intervention period.\n\nThe Specific Aims of the study are (1) to evaluate whether BBM, SM, and\u002For their combination is superior to control in reducing BPSD severity (primary outcome); (2) to evaluate whether BBM, SM, and\u002For their combination is superior to control in reducing caregiver distress (secondary outcomes); and (3) to evaluate the effects of BBM, SM, and\u002For their combination on improving overall well-being and mood (secondary outcomes).",[27,28,29,30],"BPSD","Caregiver Distress","Well-being","Mood",[32,29,30,28,33,34,35,36,37,38],"Dementia","Personalized Music Listening","Binaural Beat Stimulation","Spatial Audio","Artificial Intelligence","Randomized Controlled Trial","Assisted Living Residences","RECRUITING","2026-05-29",{"date":42,"type":43},"2026-06-04","ACTUAL",{"date":45,"type":43},"2026-05-04",{"date":47,"type":21},"2026-06-27",{"name":49,"class":50},"Maharishi International University","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100631353","multi-modal-large-language-model-empowered-talk-therapy-for-older-adults-with-adrd-100631353","NCT07499570","Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD","SVR","For the patient:\n\nInclusion criteria:\n\n* age ≥ 65 years\n* diagnosis of MCI (mild cognitive impairment) or mild ADRD\n* access to a reliable internet connection\n* community-dwelling\n* elevated behavioral and psychological symptoms of dementia (BPSD), indicated by a HABC (Healthy Aging Brain Care) monitor score above 14 on caregiver report or self report (indicating elevated levels of BPSD)\n* presence of one or more specific BPSD behaviors (e.g., agitation, anxiety, depression, apathy, or sleep disturbances)\n* ability to consent for themselves.\n\nExclusion criteria:\n\n* lives in an assisted living facility or nursing home\n* has moderate to severe ADRD as measured by the Quick Dementia Rating System\n* has a life expectancy of less than 6 months.\n\nFor the care partner:\n\nInclusion criteria:\n\n* ≥ 21 years old\n* self-identified care partner (e.g., is knowledgeable about the patient's daytime and nighttime behaviors) of a community-dwelling patient diagnosed with MCI or mild ADRD who will also participate in the study\n\nExclusion criteria:\n\n* has MCI or dementia\n* has a severe mental illness or substance abuse\n* has a life expectancy of less than 6 months.","65 Years",{"count":60,"type":21},60,[24],"The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and Related Dementias (ADRD).\n\nSVR is designed to help older adults improve their psychological well-being and cognition. This research supports our long-term goal of designing and implementing intelligent interactive systems to improve the health of individuals with ADRD.",[64,32,27,65,66],"Mild Cognitive Impairment","BPSD (Behavioral and Psychological Symptoms of Dementia)","Reminiscence Therapy","2026-05-01",{"date":69,"type":43},"2026-05-06",{"date":71,"type":43},"2025-09-03",{"date":73,"type":21},"2027-03-01",{"name":75,"class":50},"Indiana University",1]