[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bradyarrhythmia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bradyarrhythmia":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100484236","preventive-effect-of-left-bundle-branch-area-pacing-versus-right-ventricular-pacing-on-all-cause-death-heart-failure-progression-and-ventricular-dyssynchrony-in-patients-with-substantial-ventricular-pacing-protect-sync-multicenter-prospective-randomized-controlled-trial-100484236",false,"NCT05585411","PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n1. At least 19 years old and willing and capable to give informed consent\n2. Patients who is willing and able to comply with the prescribed follow-up tests and schedule of evaluations.\n\n3 Scheduled to receive a pacemaker implant 4. Substantial percentage of V pacing rate (\\>40%) is anticipated\n\nExclusion criteria:\n\n1. Incapacitated or unable to read or write\n2. Patient who is an indication of ICD or CRT\n3. History of prosthetic valve surgery on tricuspid valve\n4. Prior myocardial infarction including ventricular septum\n5. Life expectancy \\\u003C 12 months due to any condition\n6. Unavailable for at least 24 months of follow-up visits\n7. Pregnant or breastfeeding at the time of signing consent\n8. Prior Heart transplant surgery\n9. Persistent Left Superior Vena Cava (PLSVC)","ALL","19 Years",{"count":18,"type":19},450,"ESTIMATED","INTERVENTIONAL",[22],"NA","PROTECT-SYNC study is a multicenter, randomized, controlled trial. A total of 7 medical centers across Republic of Korea will enroll 450 patients during 2 years of enrollment period, and followed for 2 years of follow-up period. The purpose of this study to compare the clinical outcomes of Left Bundle Branch Area Pacing (LBBAP) compared to Right Ventricular Pacing (RVP) in bradyarrhythmia patients who require high burden of ventricular pacing (\\>40%).",[25,26,27],"Bradyarrhythmia","Atrioventricular Block","Left Bundle Branch Area Pacing",[29,30,31,32],"Left Bundle Branch Area pacing","Right Ventricular Pacing","Heart Failure","Atrioventricular block","RECRUITING","2025-12-30",{"date":36,"type":37},"2026-01-05","ACTUAL",{"date":39,"type":37},"2022-11-01",{"date":41,"type":19},"2026-11-01",{"name":43,"class":44},"Yonsei University","OTHER",8,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":15,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":83,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100541040","contemporary-cardiac-stimulation-in-clinical-practice-left-biventricular-right-and-conduction-system-pacing-100541040","NCT06324682","ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","Evaluation of conTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","TREEBEARD","Inclusion Criteria:\n\n* Indication for cardiac stimulation\n* Having performed the implantation of a device for cardiac stimulation\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years;\n* Pregnancy status;","18 Years",{"count":56,"type":19},8400,"OBSERVATIONAL","The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical practice of the participating centres. The contribution of non-fluoroscopic anatomical and electrophysiological reconstruction systems to device implantation procedures will also be evaluated.\n\nParticipants \\[patients over 18 years old with an indication to receive a definitive pacemaker\u002Fintracardiac defibrillator implant\\] will receive a permanent cardiac pacing implant as requested according to European Society of Cardiology (ESC) guidelines; the investigators will evaluate procedural efficacy and safety of different implantation approaches.",[60,26,61,62,25,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82],"Arrhythmias, Cardiac","Reduced Systolic Function","Atrial Fibrillation","Ventricular Tachycardia","Ventricular Dysfunction","Ventricular Fibrillation","Ventricular Arrythmia","Atrioventricular Nodal Disease","Atrioventricular Conduction Defects","Atrioventricular Block Complete","Atrioventricular Block Incomplete","Atrioventricular Junctional Rhythm","Bundle-Branch Block","Left Bundle-Branch Block","Heart Failure, Systolic","Block;Atrioventricular","Block; Arrhythmic","Block; Mobitz","Block, Heart","Block, Fascicular","Block Branch Bundle Left","Heart Failure，Congestive","Heart Arrhythmia",[84,85,26,25,64,86,87,88,89,90,91,92,93,69,94,66,65,63],"Pace maker (PM)","Implantable cardioverter defibrillator (ICD)","Cardiac Resynchronization therapy","Conduction System Pacing","His Pacing","Left bundle branch area pacing (LBBAP)","CRT","CSP","Primary prevention","Secondary prevention","Heart failure","2024-03-19",{"date":97,"type":37},"2024-03-22",{"date":99,"type":37},"2023-01-01",{"date":101,"type":19},"2034-12-31",{"name":103,"class":44},"University Hospital of Ferrara",31]