[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"brain-plasticity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:brain-plasticity":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100636401","effect-of-aitbs-on-intrinsic-spectral-dynamics-and-task-performance-100636401",false,"NCT07565207","Effect of aiTBS on Intrinsic Spectral Dynamics and Task Performance","The Effect of Within-network aiTBS on Cortical Excitability, Intrinsic Oscillatory Bands, and Behavioral Task Performance","Inclusion Criteria:\n\n* Able to give their consent\n* Right-handed or ambidextrous\n\nExclusion Criteria:\n\n* Non-english speaking\n* Current or past non-anxiety-related psychiatric comorbidity.\n* Active or history of active suicidal ideation\n* Alcohol\u002Fdrug problems in the past year or lifetime alcohol or drug dependence\n* Medications that act on the central nervous system\n* History of seizure\n* History of epilepsy\n* Increased risk of seizure for any reason\n* Pregnancy, or positive pregnancy test\n* Any medical (e.g., stroke, breathing problems, motion disorders) or neurological (e.g., a significant brain injury or brain infection history that increases seizure risk) condition that increases risk for fMRI or TMS (Protocol will follow recommendations from Rossi et al. 2021 doi:10.1016\u002Fj.clinph.2020.10.003)\n* Any metal in their body which would make having an MRI scan unsafe\n* Any sort of medical implants\n* Hearing loss\n* Claustrophobia\n* orthostatic hypotension",true,"ALL","18 Years","50 Years",{"count":21,"type":22},80,"ESTIMATED","INTERVENTIONAL",[25],"NA","Aim 1: Measure local shifts in cortical spectral dynamics following aiTBS. Aim 2: Measure network-specific shifts in task performance following aiTBS. Exploratory aim: Evaluate changes to resting state spectral dynamics in absence of stimulation after aiTBS.",[28],"Brain Plasticity",[30,31],"transcranial magnetic stimulation","electroencephalography","NOT_YET_RECRUITING","2026-04-27",{"date":35,"type":36},"2026-05-04","ACTUAL",{"date":38,"type":22},"2026-06-01",{"date":40,"type":22},"2030-05-30",{"name":42,"class":43},"University of Pennsylvania","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":16,"sex":17,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100509349","orchestra-in-class-a-novel-booster-for-executive-functions-and-brain-development-in-young-primary-school-children-100509349","NCT05912270","Orchestra in Class, a Novel Booster for Executive Functions and Brain Development in Young Primary School Children","ORBIT","Inclusion Criteria:\n\n* School grade 3P\u002F4P (3rd and 4th year of elementary school (6-8-year-old children)\n* Right-handedness\n* Sufficient Mastery of the French Language\n* Able to give oral informed consent (child)\n* Able to give written informed consent (parent)\n\nExclusion Criteria:\n\n* Non-consent (children and or parents)\n* Repeated or skipped a class with respect to standard curriculum\n* Not corrected\u002Fsevere hearing deficits\n* Not corrected\u002Fsevere vision deficits\n* Severe neurodevelopmental disorders (eg. severe dyslexia, severe ADHD)\n* Older than 7 at the beginning of the school year if 3P\n* Older than 8 at the beginning of the school year if 4P\n* Protocolled music instrumental practice in the preceding year\n* Protocolled visual arts courses in the preceding year\n* MRI incompatibility (physical or psychological)\n* Psychometric battery incompatibility (psychological)","6 Years","8 Years",{"count":54,"type":22},150,[25],"How to optimally stimulate the developing brain is still unclear. Executive functions (EF) exhibited substantially stronger far transfer effects in children who learned to play a musical instrument than in children who acquired other arts.\n\nWhat is crucially lacking is a large-scale, long-term genuine randomized controlled trial (RCT) in cognitive neuroscience, comparing musical instrumental training (MIP) to another art form and a control group. Collected data of this proposal will allow, using machine learning, to build a data-driven multivariate model of children's interconnected brain and EF development over the first 2 years of their academic curriculum (6-8 years), with or without music or other art training.",[58,59,60,61,62,28,63,64,65,66,67],"Development, Child","Executive Functions","Interventions","Music","Arts","Behavior","Brain Imaging","Magnetic Resonance Imaging","Functional Magnetic Resonance Imaging","Structural Brain Connectivity","RECRUITING","2023-12-12",{"date":71,"type":36},"2023-12-18",{"date":71,"type":22},{"date":74,"type":22},"2027-04-30",{"name":76,"class":43},"School of Health Sciences Geneva",1]