[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breast-cancer-patients-diagnosed\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breast-cancer-patients-diagnosed":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100619810","cardioprotective-effect-of-melatonin-versus-vitamin-d-in-breast-cancer-patients-receiving-doxorubicin-100619810",false,"NCT07349459","Cardioprotective Effect of Melatonin Versus Vitamin D in Breast Cancer Patients Receiving Doxorubicin","Clinical Study Evaluating Cardioprotective Effect of Melatonin Versus Vitamin D in Breast Cancer Patients Receiving Doxorubicin","Inclusion Criteria:\n\n* Age from 18 to 65 years old.\n* Gender: female.\n* Positive breast cancer women who are scheduled to receive Doxorubicin.\n* Have a good performance status according to the eastern cooperative oncology group with a score of 0-2.\n* Normal baseline Echocardiography with left ventricular ejection fraction ≥ 50%.\n* Normal renal and liver function tests.\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women.\n* Women with HER-2 positive of breast cancer.\n* Formerly treated with Doxorubicin.\n* Patients with a known hypersensitivity to any of the used drugs.\n* On other concomitant vitamins or food supplements.\n* Valvular heart disease, coronary artery disease, history of congestive heart failure or cardiomyopathy.\n* Impaired Left ventricular systolic function in which the Left Ventricular Ejection Fraction \\\u003C 50%.","FEMALE","18 Years","65 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to assess the cardioprotective effect of melatonin and vitamin D in breast cancer patients who receive doxorubicin.",[27,28,29,30],"Melatonin","Breast Cancer Patients Diagnosed","Vitamin D Concentration","Doxorubicin",[32,30,33,27,34],"Vitamin D","Cardioprotective Effect","Breast Cancer Patients","NOT_YET_RECRUITING","2026-01-09",{"date":38,"type":39},"2026-01-16","ACTUAL",{"date":41,"type":21},"2026-04-30",{"date":43,"type":21},"2026-08-30",{"name":45,"class":46},"Tanta University","OTHER"]