[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breast-cancer-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breast-cancer-surgery":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,52,85,120,149,175,210,234,259,279],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100590390","sexual-functon-in-young-women-after-breast-cancer-surgery-100590390",false,"NCT06966791","Sexual Functıon in Young Women After Breast Cancer Surgery","Examınatıon of Sexual Functıon in Young Women After Breast Cancer Surgery","Inclusion Criteria:\n\n* Individuals scheduled for surgery for breast cancer\n* Accepting to participate in the study\n* Being sexually active in the last 1 year\n* Continuation of menstruation\n\nExclusion Criteria:\n\n* Previous breast cancer surgery\n* Previous history of breast cancer\n* History of any other cancer\n* Refusal to participate in the study\n* Refusal to continue working\n* Problems in her relationship with her partner","FEMALE","18 Years","50 Years",{"count":20,"type":21},52,"ESTIMATED","OBSERVATIONAL","The aim of this observational study was to analyse sexual function in young women after breast cancer surgery. The main question it aims to answer is Sexual function in young women after breast cancer surgery changes during the one-year follow-up period. Participants will answer demographic information, Female Sexual Function Scale, Breast-Q and Body Perception Scale about their sexual function, quality of life and body perception. These will be recorded before surgery and repeated 6 weeks, 6 months and 1 year after surgery.",[25,26],"Breast Cancer Surgery","Young Adult Females",[28,29,30,31,32,33,34,35,36,37,38],"sexual functions","breast cancer surgery","young adult females","Breast Cancer Treatment","quality of life","breast cancer survival","body perception","Mastectomy","Mastectomy, Modified Radical","Mastectomy, Segmental","breast conserving surgery","RECRUITING","2026-02-19",{"date":42,"type":43},"2026-02-20","ACTUAL",{"date":45,"type":43},"2024-12-30",{"date":47,"type":21},"2026-07-25",{"name":49,"class":50},"ATİYE KAŞ ÖZDEMİR","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":59,"targetDuration":61,"studyType":22,"phases":4,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100585763","preoperative-magnetic-tracking-in-breast-surgery-in-france-french-medical-economic-study-100585763","NCT06906601","Preoperative Magnetic Tracking in Breast Surgery in France: French Medical-economic Study.","MAGNETO","Inclusion Criteria:\n\n* I1. Female aged ≥ 18 years;\n* I2. Patient presenting with a unifocal and unilateral lesion of invasive carcinoma or in situ;\n* I3. Indication for first breast-conserving treatment with the need for preoperative localization of the lesion, regardless of the associated lymph node procedure;\n* I4. Patient affiliated with a health insurance system;\n* I5. Non-opposition to the study.\n\nExclusion Criteria:\n\n* E.1. Psychological, family, or sociological condition that may potentially compromise adherence to the treatment protocol and follow-up;\n* E.2. Bilateral surgery required;\n* E.3. Patient with metastatic breast cancer;\n* E.4. Multifocal or benign lesions;\n* E.5. Pregnant or breastfeeding patient;\n* E.6. Need for neoadjuvant treatment;\n* E.8. Patient under guardianship, curatorship, or deprived of liberty.",{"count":60,"type":21},772,"6 Months","MAGNETO is a French medico-economic study on preoperative localization in breast cancer surgery. The main objective is to conduct a cost-consequence analysis comparing magnetic clip localization with the use of metallic wires for the preoperative identification of non-palpable breast lesions. The choice of localization method is left to the physician's and center's discretion. The study is non-interventional (with only questionnaires and data collection), prospective, and multicenter, with patient follow-up lasting up to six months after breast surgery.",[64,65,25],"Breast Cancer","Medico-economic Impact",[67,68,29,69,70,71,72,73,74],"cancer","breast cancer","preoperative localization","magnetic clip","wire localization","health economic study","Cost-consequence analysis","medico-economic","2026-02-16",{"date":77,"type":43},"2026-02-17",{"date":79,"type":43},"2025-04-15",{"date":81,"type":21},"2027-10-15",{"name":83,"class":50},"Centre Leon Berard",7,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":96,"conditions":97,"keywords":98,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":119},"100584365","long-term-safety-of-nipple-sparing-mastectomy-in-women-with-high-penetrance-breast-cancer-susceptibility-genes-in-breast-cancer-100584365","NCT06888388","Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer","Long-term Oncologic Safety of Nipple Sparing Mastectomy in Women With High Penetrance Germline Pathogenic Variants in Breast Cancer Susceptibility Genes","NSM","Inclusion Criteria:\n\n* Assigned female sex at birth\n* Age 18 years or older\n* Confirmed GPV in BRCA1, BRCA2, PALB2, TP53, CDH1 or PTEN identified on pre-symptomatic genetic testing\n\nExclusion Criteria:\n\n* History of breast cancer prior to genetic testing\n* History of ovarian cancer prior to genetic testing\n* History of bilateral mastectomy performed prior to genetic testing\n* Presence of a variant of uncertain significance (VUS) in the absence of another GPV in BRCA1, BRCA2, PALB2, TP53, CDH1 or PTEN.","90 Years",{"count":95,"type":21},4700,"Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) often strongly desire to keep their nipple areola complex but inquire as to whether it is safe to do so. Relative to traditional or skin sparing mastectomy (SSM) techniques, nipple sparing mastectomy (NSM) is associated with improved psychosocial and sexual well-being and is significantly better for body image and reducing feelings of disfigurement.\n\nDespite this, guidelines have yet to endorse the use of NSM over other RRM techniques, stating that more data and longer follow-up are needed to confirm it as a safe and effective strategy in GPV carriers. As NSM was not routinely adopted in high-risk patient populations undergoing RRM before 2010, there has been little data to inform the long-term oncologic safety of NSM. Well-designed studies have reported low to negligible rates of subsequent breast cancer in BRCA1\u002F2 carriers following NSM, but have been limited by short median follow-up of less than 3 years. The current study is designed to confirm, with longer follow-up, prior findings on the oncologic safety of NSM in unaffected BRCA1\u002F2 carriers. The investigators will also expand data to other high-penetrance GPV carriers, including PALB2, CDH1, PTEN, and TP53, for whom there is little-to-no data on outcomes following RRM.",[25],[29,99,100,101,102,103,104,105,106,107,108,109],"nipple sparing mastectomy","oncologic safety","Cancer prevention","Breast Cancer Prevention","BRCA","germline pathogenic variant","GPV","Li Fraumeni","Hereditary lobular breast cancer","Cowden syndrome","PALB2","2025-12-01",{"date":112,"type":43},"2025-12-08",{"date":114,"type":43},"2025-02-01",{"date":116,"type":21},"2028-02-01",{"name":118,"class":50},"Sir Mortimer B. Davis - Jewish General Hospital",12,{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":126,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":128,"targetDuration":4,"studyType":130,"phases":131,"briefSummary":133,"conditions":134,"keywords":138,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":51},"100589790","confocal-histolog-scanner-in-routine-breast-conserving-surgery-chib-100589790","NCT06958991","Confocal Histolog Scanner in Routine Breast-Conserving Surgery (CHiB)","Confocal Histolog Scanner in Routine Breast-Conserving Surgery","CHiB","Inclusion Criteria:\n\n* Adult female Subject ≥18 years old.\n* Subject scheduled for breast conserving surgery of invasive and\u002For in-situ ductal and lobular carcinoma.\n* Subject is able to read, understand and sign the informed consent.\n\nExclusion Criteria:\n\n* Subject with planned mastectomy\n* Subject does not speak French- Subject with planned tumor-adapted breast reduction\n* Subject is pregnant\u002F lactating. Subjects pregnant\u002Flactating are excluded because such subjects are presenting additional risks during the surgery and they are also rare.\n* Participation in any other clinical study that would affect data acquisition.",{"count":129,"type":21},100,"INTERVENTIONAL",[132],"NA","The clinical performance study is collecting data from the use of a CE mark product used within the scope of its intended purpose to intraoperatively visualize tissue specimen. The subjects are not submitted to invasive and burdensome procedures compared to the standard of care surgical practices and regular use of the CE mark product.",[135,25,136,137],"Breast Cancer Invasive","Lumpectomy","Confocal Laser Endomicroscopy",[29,139],"confocal microscopy","2025-11-22",{"date":142,"type":43},"2025-11-25",{"date":144,"type":43},"2025-06-01",{"date":146,"type":21},"2026-09-30",{"name":148,"class":50},"University of Fribourg",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":155,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":157,"minAge":17,"maxAge":4,"enrollmentInfo":158,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":160,"conditions":161,"keywords":163,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":51},"100574585","quality-of-life-after-breast-cancer-surgery-100574585","NCT06761196","Quality of Life After Breast Cancer Surgery","Assessing Quality of Life After Breast Cancer Surgery: a Prospective Cohort Study","SOCOM-QoL","Inclusion Criteria:\n\n* Patient aged 18 or over\n* Patient with breast cancer of any stage (including in situ) or healthy individual at high personal risk.\n* Patient requiring breast surgery under general anesthesia, whether for therapeutic or prophylactic purposes.\n* Patient capable, in the opinion of the investigator, of complying with the requirements and restrictions of the study.\n* Patient with a computer, tablet or smartphone connected to the Internet.\n* Patient followed in the center on a regular basis according to standard recommendations.\n\nExclusion Criteria:\n\n* Patient requiring surgical intervention under local anesthesia only.\n* Patient requiring surgery for the installation or removal of an chemotherapy implantable port only.\n* Patients with a history of cancer other than breast cancer. Patients with a history of cancer more than three years old are eligible if they are treated and considered cured. Patients with a history of cervical carcinoma in situ or non-melanoma skin carcinoma are eligible.\n* Impossibility of being subject to regular monitoring for geographical, social or psychological reasons.\n* Patient under protective measure","ALL",{"count":159,"type":21},1500,"The goal of this observational study is to prospectively collect data on quality of life after oncoplastic breast surgery.\n\nParticipants will be followed-up and answer quality of life questionnaire for a duration of 5 years after surgery.",[25,162],"Quality of Life",[68,164,32,165],"oncoplastic surgery","quality of recovery","2025-09-05",{"date":168,"type":43},"2025-09-08",{"date":170,"type":43},"2025-09-02",{"date":172,"type":21},"2035-09-01",{"name":174,"class":50},"Centre Hospitalier de Colmar",{"id":176,"slug":177,"hasResults":11,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":183,"enrollmentInfo":184,"targetDuration":4,"studyType":130,"phases":186,"briefSummary":187,"conditions":188,"keywords":192,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":208,"locationsCount":51},"100587591","improvement-in-breast-skin-sensibility-after-breast-reconstruction-a-comparison-of-3-surgical-techniques-100587591","NCT06930378","Improvement in Breast Skin Sensibility After Breast Reconstruction: a Comparison of 3 Surgical Techniques","Sensory Restoration in DIEP Free Flaps for Post-Mastectomy Breast Reconstruction After Breast Cancer: Comparing Non-sensitized Standard Technique to Direct Nerve Suture and to Autograft: A Three-arm, Randomized, Double-blinded Superiority Trial","S-DIEP","A) Pilot study\n\nInclusion criteria:\n\n* 18-80 years old\n* having received DIEP flap breast reconstruction with a flap not completely buried\n* having given written informed consent for participating in the study\n\nExclusion criteria:\n\n* postoperative radiotherapy on the flap\n* neurological conditions as diabetic neuropathy, alcoholism or any other severe underlying peripheral neuropathy including chemotherapy-induced neuropathy or neuropathy induced by other medications\n* active smoking\n* language barrier\n* pregnancy or lactating women\n\nB) Main study\n\nInclusion Criteria:\n\n* 18 to 80 years old\n* having given written informed consent for participating in the study\n* receiving immediate or delayed unilateral DIEP breast reconstruction with a DIEP flap which will not be completely buried\n\nExclusion Criteria:\n\n* autologous reconstruction where the flap is completely buried\n* patients in need of both-sided reconstruction (double DIEP)\n* postoperative radiotherapy on the flap\n* neurological conditions as diabetic neuropathy, alcoholism, or any other severe underlying peripheral neuropathy including chemotherapy-induced neuropathy or neuropathy induced by other medications\n* active smoking\n* language barrier\n* pregnancy at time of planned DIEP flap surgery and lactation","80 Years",{"count":185,"type":21},63,[132],"The goal of this clinical trial is to learn if nerve sutures in free flap breast reconstruction can optimize sensibility in the reconstructed breast in patients opting for DIEP flap breast reconstruction due to breast cancer or genetic conditions. Affected women 18 to 80 years old can be included. The main question is:\n\nIf a nerve suture was carried out, can pressure be felt better on the reconstructed breast after 12 months? If a nerve suture was carried out, will better sensibility and quality of life be felt and perceived (questionnaire) at 12 and 24 months after the initial operation ? Researchers will compare two different nerve suture techniques and no nerve suture to one another to see if and which nerve suture optimizes sensibility.\n\nParticipants will have regular visits and follow-up controls, during which\n\n* their sensibility will be tested multimodally,\n* they will fill out questionnaires\n* skin biopsies will be taken.",[25,189,190,191],"Reconstruction Breast Surgery","Sensitization","DIEP Flap Breast Reconstruction",[193,194,195,196,197,198,199,200],"free flap","breast reconstruction","autologous-based reconstruction","neurotization","sensory recovery","post-mastectomy sensation","autologous breast reconstruction","DIEP flap","2025-04-08",{"date":203,"type":43},"2025-04-16",{"date":205,"type":21},"2025-04",{"date":207,"type":21},"2029-02",{"name":209,"class":50},"Patricia Esther Engels",{"id":211,"slug":212,"hasResults":11,"nctId":213,"briefTitle":214,"officialTitle":215,"acronym":216,"eligibilityCriteria":217,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":218,"enrollmentInfo":219,"targetDuration":4,"studyType":130,"phases":221,"briefSummary":222,"conditions":223,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":227,"startDateStruct":229,"completionDateStruct":230,"leadSponsor":232,"locationsCount":51},"100575504","effect-of-subanesthetic-dose-of-esketamine-on-sleep-quality-100575504","NCT06773143","Effect of Subanesthetic Dose of Esketamine on Sleep Quality","Effect of Subanesthetic Dose of Esketamine on Sleep Quality in Patients With Breast Cancer After Chemotherapy","EOSDOEOSQ","Inclusion Criteria:\n\n1. Patients diagnosed with breast cancer by pathology and immunohistochemistry\n2. Patients receiving neoadjuvant chemotherapy\n3. Age 18 to 65 years old; d) ;\n4. ASA grade Ⅰ - Ⅲ\n5. BMI 18 to 30 kg\u002Fm2\n\nExclusion Criteria:\n\n* 1: Patients refuse to participate in the study\n\n  2: BMI \\> 30 kg\u002Fm2\n\n  3: Recent history of drug abuse\n\n  4: Allergy to or contraindications to esketamine\n\n  5: Cognitive dysfunction or inability to communicate\n\n  6: Severe dysfunction of important organs such as liver and kidney function","65 Years",{"count":220,"type":21},184,[132],"The goal of this clinical trial is to explore whether subanesthetic doses of esketamine can improve the sleep quality of patients undergoing modified radical mastectomy for breast cancer. In this study, 184 people are expected to participate from admission to three days after surgery.\n\nThe process requires participants to cooperate with the completion of the digital rating scale, the Athens Insomnia Scale, the Visual Analog Pain Rating Scale, the Hospital Anxiety and Depression Rating Scale, and the collection of venous blood for research indicators (IL-6, TNF-α, cor, BDNF).\n\nIf participants agree to participate in this study, the investigators will assign a unique identification number to each participant and create a medical record for participants.\n\nOne day before surgery, the investigators will conduct assessments using the Athens Insomnia Scale, the Visual Analog Pain Rating Scale, and the Hospital Anxiety and Depression Scale, and collect approximately 6 mL of venous blood.\n\nOne day after surgery, the investigators will repeat the assessments using the Athens Insomnia Scale, the Visual Analog Pain Rating Scale, and the Hospital Anxiety and Depression Scale. Additionally, the investigators will collect another 6 mL of venous blood and monitor the use of analgesics.\n\nThe investigators will follow up with participants three days after the surgery. During this follow-up, investigators will assess any sleep disturbances, administer the Hospital Anxiety and Depression Scale, and review the use of analgesics.",[224,25,225],"Insomnia","Esketamine","2025-02-06",{"date":228,"type":43},"2025-02-10",{"date":45,"type":43},{"date":231,"type":21},"2027-04-30",{"name":233,"class":50},"Nanjing First Hospital, Nanjing Medical University",{"id":235,"slug":236,"hasResults":11,"nctId":237,"briefTitle":238,"officialTitle":239,"acronym":240,"eligibilityCriteria":241,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":183,"enrollmentInfo":242,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":244,"conditions":245,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":249,"lastUpdatePostDateStruct":250,"startDateStruct":252,"completionDateStruct":254,"leadSponsor":256,"locationsCount":51},"100561583","affecting-factors-for-chronic-pain-after-mastectomy-100561583","NCT06592053","Affecting Factors for Chronic Pain After Mastectomy","Affecting Factors for the Incidence of Chronic Pain After Mastectomy","CPMP","Inclusion Criteria:\n\n* Between the ages of 18-80\n* BMI 18-35 kg\u002Fm2\n* ASA (American Society of Anesthesiologists) Scoring I-II-III\n* Elective mastectomy surgery\n* Elective mastectomy and axillary dissection surgery\n* Patients who will undergo general anesthesia\n* Patients who agree to participate in the study and sign a form\n\nExclusion Criteria:\n\n* Patients under 18 and over 80 years of age\n* Patients who do not want to participate in the study\n* Patients with chronic pain or chronic opioid use\n* Patients with alcohol, substance or drug addiction\n* Patients with a history of previous mastectomy\n* Patients with limited cooperation such as dementia, psychiatric disorders\n* Pregnant and breastfeeding patients will be excluded from the study\n* Patients who cannot communicate in their native language will be excluded from the study",{"count":243,"type":21},200,"Chronic post-mastectomy pain (CPMP) is a significant issue affecting many women after mastectomy. Factors like age, treatment type, and pre-surgery pain can increase the risk of developing this condition. By evaluating these factors, CPMP can be prevented more successfully and treatment strategies can be developed. This study aims to investigate the factors contributing to CPMP and contribute to the existing literature on this important topic.",[35,246,247,248,25],"Pain, Chronic","Pain, Acute","Breast Surgery","2025-01-31",{"date":251,"type":43},"2025-02-04",{"date":253,"type":43},"2024-09-25",{"date":255,"type":21},"2026-10-30",{"name":257,"class":258},"Ankara Etlik City Hospital","OTHER_GOV",{"id":260,"slug":261,"hasResults":11,"nctId":262,"briefTitle":263,"officialTitle":264,"acronym":4,"eligibilityCriteria":265,"healthyVolunteers":11,"sex":157,"minAge":17,"maxAge":266,"enrollmentInfo":267,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":269,"conditions":270,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":271,"lastUpdatePostDateStruct":272,"startDateStruct":274,"completionDateStruct":276,"leadSponsor":277,"locationsCount":51},"100577558","localization-of-breast-cancer-with-the-sirius-pintuition-magnetic-seed-100577558","NCT06799858","Localization of Breast Cancer with the Sirius Pintuition Magnetic Seed","Localization of Breast Cancer with the Sirius Pintuition Magnetic Seed: a Pilot Study in the Czech Republic","Inclusion Criteria:\n\n* breast cancer confirmed by a core-cut biopsy\n* localisation of non-palpable breast cancer or pathological lymph node with a magnetic seed Sirius Pintuition\n* breast cancer surgery in Surgical dpt, Silesian Hospital in Opava\n\nExclusion Criteria:\n\n* disagree with participation in the study","99 Years",{"count":268,"type":21},40,"A prospective pilot study in the Czech Republic examining the use of magnetic seed Sirius Pintuition for the localization of non-palpable malignant breast tumors and pathological lymph nodes.",[25],"2025-01-28",{"date":273,"type":43},"2025-01-29",{"date":275,"type":43},"2024-04-01",{"date":144,"type":21},{"name":278,"class":50},"Jan Žatecký",{"id":280,"slug":281,"hasResults":11,"nctId":282,"briefTitle":283,"officialTitle":284,"acronym":4,"eligibilityCriteria":285,"healthyVolunteers":11,"sex":157,"minAge":17,"maxAge":4,"enrollmentInfo":286,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":288,"conditions":289,"keywords":291,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":292,"lastUpdatePostDateStruct":293,"startDateStruct":295,"completionDateStruct":296,"leadSponsor":298,"locationsCount":51},"100565435","onset-of-sensory-block-after-thoracic-esp-block-100565435","NCT06642142","Onset of Sensory Block After Thoracic ESP Block","Evaluation of the Onset and the Extent of Sensory Block After Thoracic ESP Block in Breast Surgery - a Prospective Observational Study","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* ASA score I-II-III.\n* Schedule of breast surgery\n* Schedule of ESPB\n* Consent to the study\n\nExclusion Criteria:\n\n* Allergy to local anaesthetics\n* Cardiopathies, nephropathies, hepatopathies, central or peripheral neuropathies uncompensated\n* Infection at the injection site\n* Uncooperative patient\n* BMI \\\u003C 20, \\> 40\n* Difficulty in visualising target structures or the LA spread (failure of technique)\n* Pregnancy status",{"count":287,"type":21},30,"The goal of this observational study is to to evaluate the changes in cold sensitivity and the onset of sensory block after performing a thoracic ESP block. It reflects the time it takes for the local anaesthetic to spread into the paravertebral space leading to changes in cold sensitivity in the chest.\n\nThe study population are patients undergoing simple quadrantectomy or partial resection with or without sentinel lymphnode removal, in the operating rooms of Santa Maria Goretti Hospital in Latina.\n\nThis study is observational because it simply describes and records the effects of a procedure (the ESP block) on treated patients during a period of observation.\n\nBefore surgery, unilateral thoracic ESP block (T4 level) with a sterile, ultrasound-guided technique will be performed. A timer will be started to mark the time for subsequent evaluations. At 1,3,5 and after every 5 minutes following the block up to 40 minutes or until induction of general anaesthesia, the cold sensitivity of the chest will be explored.",[25,290],"ESPB",[290],"2024-11-07",{"date":294,"type":43},"2024-11-08",{"date":292,"type":43},{"date":297,"type":21},"2025-10",{"name":299,"class":50},"Ospedale Santa Maria Goretti"]