[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breast-milk-expression\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breast-milk-expression":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100469865","galactagogue-use-in-lactating-women-with-low-milk-supply-100469865",false,"NCT05398367","Galactagogue Use in Lactating Women With Low Milk Supply","Effect of Single Ingredient and Blend Galactagogue Supplements on Increasing Milk Supply in Lactating Women Experiencing Diagnosed or Perceived Low Milk Supply","Inclusion Criteria: Participants in the study must:\n\n* Be struggling with diagnosed or perceived low milk supply\n* Be willing to consume a randomly assigned galactagogue or placebo supplement\n* Be willing to provide a blood sample at each lactation consult (day 1, 10, 20)\n* Be willing to provide 24-hour expressed milk volume either using pre- and post-feed weights, total pump output, or a combination of both on day 1, 10, and 20\n\nExclusion Criteria: Participants will be excluded if:\n\n* They have a history of breast reduction\n* They have a history of utilizing in vitro fertilization\n* They are not a biological female with mammary glands present for producing milk\n* They have consumed galactagogues with the intention of increasing their milk supply during the current lactation cycle\n* They are under age 18 or above age 39",true,"FEMALE","18 Years","40 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to determine whether a 20-day supplement with either Oat Mama Lactation Supplement, moringa, or shatavari has any impact on milk production through an increase in serum prolactin levels when compared to the placebo group. This data will be used to determine if clinical recommendations can be made for the use of the studied supplements in increasing milk supply.",[28],"Breast Milk Expression","RECRUITING","2025-03-24",{"date":32,"type":33},"2025-03-28","ACTUAL",{"date":35,"type":33},"2024-03-05",{"date":37,"type":22},"2026-06-01",{"name":39,"class":40},"Winthrop University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":16,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":41},"100553446","preemie-milk-analyser-validation-study-100553446","NCT06486194","Preemie Milk Analyser Validation Study","Analytical Validation and Clinical Testing of the Preemie System for Analysis and Calculation of Targeted Fortification of Mother's Breast Milk for Preterm Infants","Inclusion criteria Phase 1A For University Hospital Southampton (UHS) milk bank donors\n\n* Approved as a donor for the UHS milk bank through the usual process\n* Be providing milk to UHS donor milk bank For mothers of infant inpatients\n* Have an infant who is currently an inpatient in the neonatal unit, paediatric wards, paediatric cardiac ward, or paediatric intensive care unit\n* Be providing breastmilk for their preterm or term born infant\n* Have sufficient breast milk available such that providing 120ml breast milk for the study does not impact on the needs of their infant.\n\nInclusion criteria Phase 1B\n\n* Approved as a donor for the UHS milk bank through the usual process\n* Be providing milk to UHS donor milk bank\n\nExclusion criteria Phase 1A and 1B For mothers of infant inpatients\n\n\\- Mothers whose infants are inpatients and where there is a concern about adequacy of maternal milk supply to feed their infant\n\nInclusion Criteria Phase 2\n\n* Birth weight ≥1kg and \\\u003C1.8 kg (so meet the ESPGHAN criteria for breast milk fortification)\n* Be taking fully fortified enteral breast milk feeds (≥150 ml\u002Fkg\u002Fday of mothers or donor breast milk containing breast milk fortifier as per the manufacturer's instructions)\n* Tolerating fully fortified breast milk feeds≥150 ml\u002Fkg\u002Fday for 48 hours\n* No longer on parenteral nutrition.\n\nExclusion Criteria Phase 2\n\n* Infants where there is a concern about mother's supply of breast milk being insufficient to meet demands (where donor milk is not being used to make up any shortfall);\n* Known congenital metabolic disorder;\n* Infant formula fed;\n* Bilateral grade III or IV intraventricular haemorrhage;\n* Any infant who has had gastrointestinal tract surgery;\n* Refusal of consent;\n* Refusal for the use of breast milk fortifier\n* Birthweight \\\u003C1 kg","ALL","0 Days","50 Years",{"count":53,"type":22},180,[25],"This study aims to test and validate the Preemie Ecosystem- a new device and associated software package for measuring the nutrient (fat, protein and carbohydrate) content of the breast milk of the mothers of premature babies. This is potentially useful, as premature babies have higher nutritional requirements than babies born at term near their due date. At the moment, a nutritional supplement called breast milk fortifier is added to breast milk in standard amounts to improve its nutritional content and help premature babies grow. However, we know that each mother's breast milk is different, and varies from day to day, so each mother's milk may require more or less of such supplements in order to meet European recommendations for the nutrient intake.\n\nThe aim of this study is to first test and validate the accuracy of the Preemie device for measuring the nutritional content of mother's breast milk, using milk donated to the local donor milk bank and from mothers of babies currently on the neonatal unit. Next, once this is complete, the aim is to demonstrate it is feasible to use the Preemie device to enable fortification of mother's milk on an individualised basis for a small group of premature babies. The growth and nutrient intakes of these babies will be compared to another group who are cared for using the standard fortification approach.\n\nThe results of this study will be used to gain \"Conformité Européenne\" (CE) certification of the Preemie device and software.",[57,28,58],"Pre-Term","Nutrition Disorder, Infant","NOT_YET_RECRUITING","2024-06-26",{"date":62,"type":33},"2024-07-03",{"date":64,"type":22},"2024-07-01",{"date":66,"type":22},"2026-07-01",{"name":68,"class":40},"University Hospital Southampton NHS Foundation Trust"]