[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breast-ptosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breast-ptosis":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100641052","autologous-free-dermal-graft-support-in-superior-pedicle-vertical-scar-reduction-mammaplasty-100641052",false,"NCT07657962","Autologous Free Dermal Graft Support in Superior Pedicle Vertical Scar Reduction Mammaplasty","Effect of Autologous Free Dermal Graft Use on Lower Pole Stability in Superior Pedicle Vertical Scar Reduction Mammaplasty: A Prospective Comparative Cohort Study","Inclusion Criteria:\n\n* Female participants aged 18 to 65 years\n* Planned primary bilateral reduction mammaplasty\n* Planned use of the superior pedicle vertical scar technique\n* Willingness to attend at least 6 months of postoperative follow-up\n* Ability to provide written informed consent\n* Consent for standardized medical photography and clinical breast measurements\n\nExclusion Criteria:\n\n* Previous breast surgery\n* Oncoplastic breast reduction\n* Unilateral reduction mammaplasty\n* Use of a pedicle technique other than the superior pedicle\n* Use of a scar pattern other than the vertical scar pattern\n* Presence of a systemic condition expected to significantly impair wound healing\n* Active smoking within the last 6 weeks before surgery\n* Incomplete 6-month follow-up data for the primary outcome analysis","FEMALE","18 Years","65 Years",{"count":20,"type":21},70,"ESTIMATED","6 Months","OBSERVATIONAL","The goal of this observational study is to learn whether using an autologous free dermal graft during breast reduction surgery helps maintain lower breast pole shape over time in women undergoing primary bilateral reduction mammaplasty.\n\nThe main question it aims to answer is:\n\nDoes autologous free dermal graft support reduce lower pole lengthening between 1 month and 6 months after surgery?\n\nResearchers will compare two groups of participants. One group will undergo superior pedicle vertical scar reduction mammaplasty with autologous free dermal graft support as part of routine surgical care. The other group will undergo the same basic breast reduction technique without autologous free dermal graft support.\n\nParticipants will:\n\n* Have their planned breast reduction surgery as part of routine care\n* Attend postoperative follow-up visits at 1, 3, and 6 months\n* Have standard breast measurements and medical photographs taken during follow-up\n* Complete a breast satisfaction questionnaire at 6 months",[26,27,28,29],"Breast Ptosis","Mammaplasty","Lower Pole Elongation","Postoperative Breast Pseudoptosis",[31,32,33,34,35],"Reduction mammaplasty","Superior pedicle","Autologous free dermal graft","Vertical scar reduction mammaplasty","Aesthetic outcome","NOT_YET_RECRUITING","2026-06-14",{"date":39,"type":40},"2026-06-18","ACTUAL",{"date":42,"type":21},"2026-08-01",{"date":44,"type":21},"2028-02-01",{"name":46,"class":47},"Cumhuriyet University Hospital","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":48},"100608102","hybrid-autologous-breast-augmentation-in-mastopexy-with-internal-bra-fixation-using-local-breast-tissues-and-fat-grafting-100608102","NCT07197190","Hybrid Autologous Breast Augmentation in Mastopexy With Internal BRA Fixation; Using Local Breast Tissues and Fat Grafting","Inclusion Criteria:\n\n1. Female patient\n2. Grade 2 or 3 breast ptosis according to Regnault classification.\n3. Age is between 18 years and 50 years old.\n4. Small to moderate breast size.\n\nExclusion Criteria:\n\n1. Age is below 18 years and above 50 years.\n2. Pregnant or breast-feeding patient.\n3. Large sized breast.\n4. Grade 1 breast ptosis or pseudoptosis according to Regnault classification.\n5. Patients are currently under treatment of breast cancer.\n6. Immunosuppressed patients. -","50 Years",{"count":57,"type":21},28,"INTERVENTIONAL",[60],"NA","The breast is a very important organ for women's self-esteem and is regarded as a symbol of femininity. Deviations from normal size, shape, and symmetry are interpreted as unattractive and a sign of aging. Far from posing merely a cosmetic problem, such deviations deeply disturb both the patient's perception of her body and her emotional balance.\n\nThe first breast surgeries started as early as the 6th century, yet the aesthetic breast surgeries and specifically mastopexy techniques were first recorded in the 19th century in parallel with the evolution of reduction mammaplasty. Most of these techniques involved suspension targeting breast mound elevation.\n\nBreast ptosis refers to the downward displacement of the nipple-areola complex (NAC) below the inframammary fold (IMF), commonly due to aging, pregnancy, weight fluctuations, and genetics. It's caused by loss of skin elasticity, stretching of Cooper's ligaments, parenchymal involution, and genetic factors. The degree of ptosis can be categorized by the Regnault classification, which assesses the breast according to the relative position of the nipple to the inframammary fold (IMF):\n\nGrade 1: Mild ptosis - The nipple is at the level of the IMF. Grade 2: Moderate ptosis - The nipple is below the level of the IMF but is not the most dependent part of the breast.\n\nGrade 3: Severe ptosis - The nipple is below the IMF and is the most dependent part of the breast.\n\nPseudoptosis designates a breast configuration in which the nipple is located above or at the level of the IMF, most of the breast is well below the IMF, and the nipple-to-IMF distance is often greater than 6 cm.\n\nMastopexy procedures are similar and traditionally derived from reduction procedures, involving skin resection with no or minimal parenchymal resection. There are three main surgical goals that should be attained to correct breast ptosis and give a firm aesthetic breast shape. These include nipple areola complex (NAC) elevation, skin envelope excess management and breast reshaping. Breast flaps and parenchymal shaping manoeuvres can help auto augmentation correct any shape defects, Hence come the idea of autogenous internal bra mastopexy technique.\n\nThe term 'internal bra' refers to a range of techniques that aim to stabilise the position of the breast and improve longevity of surgical results. They can be categorised into 5 groups: mesh techniques, acellular dermal matrix (ADMs) techniques, suture techniques, dermal flap techniques, and muscle techniques. In this study, the investigators address one of the dermal flap techniques. Dermal flaps have two key advantages compared to meshes and ADMs, the first of which is that they are low cost due to their autologous nature The fact that they utilise the patient's own tissue also means they are not associated with an increased risk of infection or immunological reaction, which is their second main advantage.\n\nThere are many different types of pedicled flaps in mastopexy as medial, superior and superomedial flaps. But in this study, the investigators use the superior pedicelled flap with inferior dermal flap described by Liacyr Ribeiro.\n\nThis flap can be better mobilized than any of the other flaps, and the breast and the flap move together. The flap does not heal to pectoralis fascia; rather, the anterior surface of the flap heals to the posterior surface of the pedicle. Later, if the patient decides to have an implant, there is still a good plane between the pectoralis fascia and the inferior flap. This plane could be filled by sub pectoral fascia fat grafting.\n\nAutologous augmentation mastopexy may seem the most suitable technique for ptotic small sized breasts. But it has some drawbacks on the long term, such as upper pole hollowness. This issue can also be addressed by upper pole fullness by fat grafting.\n\nSo, in this research, the investigators do autologous internal bra mastopexy with fat grafting in two planes: Sub- fascial level for augmentation and subcutaneous level for upper pole fullness. The investigators assess the result by taking pre and post operative breast measurements and photographs. The investigators also assess participants' satisfaction level and possible complication.",[26],[64,65,66,67],"Internal Bra","Sub-pectoral lipofilling","Autologous Augmentation mastpexy","Breast fat grafting","2025-09-27",{"date":70,"type":40},"2025-10-02",{"date":72,"type":21},"2025-10-01",{"date":74,"type":21},"2028-04-01",{"name":76,"class":47},"Assiut University"]