[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breathing-exercises\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breathing-exercises":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,49,77,103,130,171,204,225,251,279,304,328,352],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100644112","effect-of-ai-assisted-respiratory-training-on-pain-fatigue-and-respiratory-parameters-in-patients-after-open-heart-surgery-100644112",false,"NCT07665593","Effect of AI-Assisted Respiratory Training on Pain, Fatigue and Respiratory Parameters in Patients After Open Heart Surgery","The Effect of Artificial Intelligence-Assisted Respiratory Training on Pain, Fatigue and Respiratory Parameters in Patients After Open Heart Surgery","Inclusion Criteria:\n\n* Patients undergoing elective open heart surgery.\n* Conscious.\n* Speaks and understands Turkish.\n* Has a chest tube inserted (on the right and\u002For left side).\n* No visual, auditory, or mental problems.\n* Willing to participate in the study.\n\nExclusion Criteria:\n\n* Undergoing concurrent other chest surgery or having a history of re-surgery.\n* Development of early postoperative complications (e.g., atelectasis) within 0-3 days.\n* Any loss of an extremity.\n* Long-term immobilization and intubation.\n* Development of severe post-surgery infections (such as mediastinitis or sepsis) or respiratory complications (such as pneumonia or atelectasis).","ALL","18 Years",{"count":19,"type":20},111,"ESTIMATED","INTERVENTIONAL",[23],"NA","This randomized controlled study aims to evaluate the effect of artificial intelligence (AI)-assisted respiratory training on fatigue, pain, and respiratory parameters in patients after open heart surgery.",[26,27,28,29],"Nursing Care","Pain","Breathing Exercises","Fatigue Recovery",[31,32,33,34,35],"pain","nursing care","fatigue","breathing exercises","open heart surgery","RECRUITING","2026-06-22",{"date":39,"type":40},"2026-06-24","ACTUAL",{"date":42,"type":40},"2026-02-10",{"date":44,"type":20},"2026-10",{"name":46,"class":47},"Kocaeli University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100609736","a-study-of-resilience-and-mental-well-being-through-breathing-practice-for-clinical-care-professionals-100609736","NCT07218458","A Study Of Resilience And Mental Well-Being Through Breathing Practice For Clinical Care Professionals","Enhancing Resilience And Mental Well-Being Through Breathing Practice For Clinical Care Professionals (Breathing Study-Burnout)","Inclusion Criteria:\n\n* Participants must be healthcare professionals at the above-mentioned 4 MCHS sites (Eau Claire, La Crosse, Mankato, Albert Lea).\n* Must score ≥40 on Copenhagen Burnout Inventory Q1-6.\n* Participants must be physically fit enough to perform light exercise.\n* Participants should read and understand English well enough to consent, complete measures, and follow instructions.\n* Participants must have access to a smartphone or tablet.\n\nExclusion Criteria:\n\n* Active primary psychotic disorder or substance use disorder (except nicotine dependence) within the past year.\n* Severe or unstable medical condition that could interfere with participation or data collection.\n* Active neurological condition (including seizure disorder, traumatic brain injury, or stroke) that could affect cognitive functioning or brain imaging results.\n* Chronic lung disease (e.g., COPD, cystic fibrosis) or aneurysm.\n* Current pregnancy or planning to become pregnant during the study period",true,"85 Years",{"count":59,"type":20},40,[23],"The purpose of this study is to assess the immediate and long-term effects of structured breathing on clinical symptoms related to mental health including anxiety, depression, perceived stress, and sleep quality.",[63,28],"Burnout, Healthcare Workers",[65,66],"burnout","breathing","2026-04-29",{"date":69,"type":40},"2026-05-05",{"date":71,"type":40},"2025-10-27",{"date":73,"type":20},"2026-11-30",{"name":75,"class":47},"Mayo Clinic",4,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":56,"sex":84,"minAge":85,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":21,"phases":88,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100635504","the-effect-of-a-breathing-and-progressive-muscle-relaxation-program-100635504","NCT07553546","THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM","THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM ON SLEEP QUALITY AND PSYCHOLOGICAL WELL_BEING IN UNIVERSITY ATHLETES: A NON- RANDOMIZED CONTROLLED INTERVENTION STUDY","Inclusion Criteria:\n\n* Being between the ages of 18 and 24\n* Being male\n* Currently actively participating in an American football team\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* Use of antiepileptic, antipsychotic, antidepressant, hormonal, or hypnotic medications Not volunteering to participate in the study","MALE","18 Months",{"count":87,"type":20},60,[23],"This non-randomized controlled study evaluates a 10-week breathing and myofascial release program in university athletes. The intervention group receives structured training, while the control group receives only an informational brochure.",[28,91,92],"PROGRESSIVE MUSCLE RELAXATION EXERCISES","Psychological Well-being","NOT_YET_RECRUITING","2026-04-20",{"date":96,"type":40},"2026-04-28",{"date":98,"type":20},"2026-05-01",{"date":100,"type":20},"2026-07-15",{"name":102,"class":47},"Marmara University",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":21,"phases":112,"briefSummary":113,"conditions":114,"keywords":118,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":48},"100452941","spinal-cord-stimulation-and-respiration-after-injury-100452941","NCT05178056","Spinal Cord Stimulation and Respiration After Injury","Epidural Spinal Cord Stimulation and Respiratory Motor Function After Injury","Inclusion Criteria:\n\n* At least 18 years old\n* Stable medical condition\n* Non-progressive C3-T1 AIS A-C Spinal Cord Injury (SCI)\n* Sustained SCI at least 24 months prior to entering the study\n* At least 15%-deficit in pulmonary function outcomes\n\nExclusion Criteria:\n\n* Painful musculo-skeletal dysfunction\n* Unhealed fracture\n* Contracture\n* Pressure sore\n* Urinary tract infection that might interfere with respiratory training\n* Clinically significant depression\n* Psychiatric disorders\n* Ongoing drug abuse;\n* Major cardiovascular disease\n* Major pulmonary disease\n* Ventilator dependence\n* Major endocrine disorders\n* Malignancy\n* Marked obesity\n* Deep vein thrombosis\n* HIV\u002FAIDS related illness\n* Secondary causes of respiratory dysfunction\n* Major gastrointestinal problems\n* Other major medical illness contraindicated for respiratory training\n* Pregnantcy",{"count":111,"type":20},30,[23],"Respiratory motor control deficit is the leading cause of morbidity and mortality in patients with spinal cord injury. The long-term goal of this NIH-funded study is to develop a rehabilitation strategy for respiration in patients with spinal cord injury as a standard of care. Respiratory function in patients with chronic spinal cord injury can be improved by using inspiratory-expiratory pressure threshold respiratory training protocol. However, the effectiveness of this intervention is limited by the levels of functional capacity preserved below the neurological level of injury. Preliminary data obtained for this study demonstrate that electrical spinal cord stimulation applied epidurally at the lumbar level in combination with respiratory training can activate and re-organize spinal motor networks for respiration. This study is designed to investigate respiratory motor control-related responses to epidural spinal cord stimulation alone and in combination with respiratory training. By characterization of respiratory muscle activation patterns using surface electromyography in association with pulmonary functional and respiration-related cardiovascular measures, the investigators expect to determine the specific stimulation parameters needed to increase spinal excitability below level of injury to enhance responses to the input from supraspinal centers that remain after injury and to promote the neural plasticity driven by the respiratory training. This hypothesis will be tested by pursuing two Specific Aims: 1) Evaluate the acute effects of epidural spinal cord stimulation on respiratory functional and motor control properties; and 2) Evaluate the effectiveness of epidural spinal cord stimulation combined with respiratory training.",[115,116,28,117],"Spinal Cord Injuries","Spinal Cord Stimulation","Rehabilitation",[119,120],"Epidural Spinal Cord Stimulation","Respiratory Training","2026-03-11",{"date":123,"type":40},"2026-03-13",{"date":125,"type":40},"2021-12-31",{"date":127,"type":20},"2030-12-31",{"name":129,"class":47},"University of Louisville",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":56,"sex":16,"minAge":137,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":21,"phases":140,"briefSummary":141,"conditions":142,"keywords":156,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":4},"100628685","feasibility-of-breathwork-intervention-with-older-adults-after-knee-surgery-100628685","NCT07464860","Feasibility of Breathwork Intervention With Older Adults After Knee Surgery","A Box Breathing Intervention and the Surgical Stress Response in Older Adults Undergoing Total Knee Arthroplasty: A Randomized Controlled Feasibility Trial","Adults aged 65 years or older of any sex, gender and ethnic background who meet the following criteria will be eligible to enroll in the present study:\n\nInclusion Criteria:\n\n* scheduled for elective TKA within the next week to two months (can be second knee, but cannot be a revision of the original knee)\n* self-reported good health, including denial of debilitating illness that may affect participation in or be potentially exacerbated by deep, controlled breathing (i.e., chronic obstructive pulmonary disorder \\[COPD\\], symptomatic or advanced heart failure, complete heart block, glaucoma, epilepsy)\n* denial of conditions that alter cortisol release or that require corticosteroid therapy (i.e., Cushing's syndrome, Addison's disease, pituitary tumors, adrenal gland tumors, asthma)\n* denial of severe psychiatric or cognitive conditions that warrant the need for a durable power of attorney (DPOA)\n* able to understand written and verbal English.\n\nExclusion Criteria:\n\n* currently taking oral, injectable, intranasal, topical, or inhaled corticosteroid medications (i.e., prednisone, hydrocortisone, dexamethasone, methylprednisolone, methylprednisolone acetate, triamcinolone, betamethasone, mometasone, fluticasone, budesonide, clobetasol)\n* do not have the technology requirements to complete data collection (i.e., participant does not have a smartphone, tablet, laptop, or desktop computer; lack of reliable internet)\n\nThe following exclusion criteria may affect participants' ability to remain in the study following enrollment:\n\n• Development of complications during surgery that require prolonged hospitalization into Postoperative Day (POD) 2 (e.g., postoperative intubation and ventilation requirements, intractable pain, intractable nausea\u002Fvomiting, signs of infection or sepsis)","65 Years",{"count":139,"type":20},32,[23],"Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients. Older adults (≥65 years) are particularly vulnerable to postoperative complications and their associated morbidities due to the biological aging process. Older adults comprise nearly half of surgical patients worldwide, and this number is expected to increase in the next 10-20 years as the aging population continues to grow. TKA is the most common procedure undergone by older adults, and the rate of TKA procedures is also expected to rise. Despite perioperative guidelines and protocols to prevent postoperative complications, the prevalence of postoperative complications following TKA is approximately 12%. Given these statistics, millions of older adults undergoing TKA may be at risk for postoperative complications and their associated morbidities in the coming decades. Therefore, additional interventions are needed to combat postoperative complications in this population.\n\nThe body's natural response to surgery, also known as the surgical stress response (SSR), contributes to postoperative complications through complex mechanisms involving the autonomic nervous system (ANS). Increased sympathetic nervous system (SNS) activity, or the body's fight-or-flight response, causes dysregulation in feedback systems that regulate the stress response, potentially leading to poorer outcomes. Interventions, such as breathwork, that induce the parasympathetic nervous system (PNS), or the body's rest-and-digest response, have been shown to balance the ANS, regulate stress biology, and improve outcomes. This study will examine the feasibility of adding a breathwork intervention (Box Breathing), compared to an attention control, to standard perioperative care for older adults undergoing TKA. This study will also examine the proof of concept that Box Breathing, compared to an attention control, may help regulate the SSR by assessing an objective measure of stress-related biology, diurnal cortisol rhythm, and gathering self-report information on pain, anxiety, depression, and quality of recovery following TKA.",[143,144,145,146,147,28,148,149,150,151,152,153,154,155],"Surgical Stress Response","Stress Physiological","Stress Physiology","Stress Psychological","Breathing Techniques","Hypothalamic Pituitary Adrenal","Relaxation","Relaxation Therapy","Cortisol","Postoperative Pain","Postoperative Anxiety","Postoperative Depression","Quality of Recovery (QoR-15)",[143,157,158,159,28,147,160,152,153,154,161,162],"Total Knee Arthroplasty","Hypothalamic-Pituitary-Adrenal Axis","Breathwork","Postoperative Complications","Quality of Recovery","Diurnal Cortisol Rhythm","2026-03-06",{"date":121,"type":40},{"date":166,"type":20},"2026-04-06",{"date":168,"type":20},"2026-09-30",{"name":170,"class":47},"University of Arizona",{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":178,"targetDuration":4,"studyType":21,"phases":180,"briefSummary":181,"conditions":182,"keywords":187,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":4},"100621908","effects-of-controlled-breathing-on-cardiorespiratory-variables-in-multiple-myeloma-100621908","NCT07376733","Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple Myeloma","Efficacy of a Controlled Breathing and Therapeutic Exercise Program on Cardiorespiratory Variables in Patients With Multiple Myeloma","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Confirmed diagnosis of multiple myeloma, currently undergoing active treatment with daratumumab, and under clinical follow-up by the Hematology Department of HU12O.\n* Explicit medical indication for supervised physical activity issued by the responsible hematologist and documented in the medical record.\n* No scheduled hematopoietic stem cell transplantation within the 60 days following the planned start date of the intervention (verified through medical record review).\n* Functional status of ECOG 0-2 (Eastern Cooperative Oncology Group), assessed by a healthcare professional from the Hematology Department, ensuring the ability to perform at least basic and light instrumental activities of daily living, including independent ambulation.\n* Access to a smartphone with stable internet connection, required for monitoring and recording adherence to the intervention.\n* Ability to provide written informed consent, demonstrating understanding of the study's nature, purpose, and procedures.\n\nExclusion Criteria:\n\n* Medical risk contraindicating exercise or breathing techniques:\n\n  * Clinically significant cardiovascular disease, including:decompensated heart failure, acute myocardial infarction within the past 3 months, clinically uncontrolled arrhythmias, unstable angina, acute-phase deep vein thrombosis or pulmonary embolism, pacemakers or cardiac devices whose monitoring parameters contraindicate supervised exercise according to cardiology.\n  * Severe decompensated respiratory disease, such as acute exacerbation of COPD, severe respiratory insufficiency, or persistently low resting oxygen saturation \\\u003C 90% (not correctable).\n* High musculoskeletal or bone risk:\n\n  * Extensive lytic bone lesions, high risk of pathological fracture, or unstable vertebral fracture, documented by imaging or based on the assessment of the Hematology\u002FTraumatology specialist.\n  * Uncontrolled pain that prevents safe participation in an exercise program.\n* Hematologic or systemic conditions contraindicating exercise:\n\n  * Severe anemia: hemoglobin \\\u003C 9 g\u002FdL in women or \\\u003C 8 g\u002FdL in men (latest laboratory test ≤ 14 days).\n  * Active systemic infection contraindicating exercise, fever ≥ 38 °C, or neutropenia \\\u003C 0.5 × 10⁹\u002FL.\n  * Severe cytopenias that, in the opinion of the hematologist, preclude moderate exercise.\n* Functional or procedural limitations:\n\n  * Inability to remain in the supine position for ≥ 5 minutes, required for part of the breathing intervention.\n  * Confirmed pregnancy or reasonable suspicion of pregnancy.\n  * Severe cognitive impairment, major psychiatric disorders, or neurological diseases that limit understanding of the procedures or safe participation.\n  * Significant difficulty understanding the language (spoken or written) that prevents following essential instructions or completing validated questionnaires.",{"count":179,"type":20},26,[23],"A randomized, parallel, double-blind, controlled, clinical trial. Two groups of participants will be included, both receiving a therapeutic exercise intervention and an educational session on the importance of proper breathing over a 6-week period. One of the groups will additionally perform a home-based controlled breathing exercise protocol. Pre- and post-intervention assessments (6 weeks) will be conducted, along with a follow-up evaluation 4 weeks after completion of the intervention. The goal is to determine the effectiveness of adding a controlled breathing exercise program to a therapeutic exercise intervention on cardiorespiratory variables in individuals with multiple myeloma.",[183,147,28,184,185,186],"Multiple Myeloma (MM)","Exercise Activity","Diaphragmatic Breathing","Heart Rate Variability (HRV)",[188,189,190,191,192,193,194],"multiple myeloma","Breathing","Diaphragmatic breathing","Slow breathing","exercise activity","Breathing exercises","heart rate variability","2026-01-21",{"date":197,"type":40},"2026-01-29",{"date":199,"type":20},"2026-01",{"date":201,"type":20},"2026-09",{"name":203,"class":47},"Universidad Complutense de Madrid",{"id":205,"slug":206,"hasResults":11,"nctId":207,"briefTitle":208,"officialTitle":209,"acronym":4,"eligibilityCriteria":210,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":211,"targetDuration":4,"studyType":21,"phases":212,"briefSummary":213,"conditions":214,"keywords":216,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":222,"leadSponsor":224,"locationsCount":4},"100617001","effects-of-controlled-breathing-added-to-therapeutic-exercise-in-multiple-myeloma-100617001","NCT07312942","Effects of Controlled Breathing Added to Therapeutic Exercise in Multiple Myeloma","Effects of Adding a Controlled Breathing Protocol to a Therapeutic Exercise Program in Adults With Multiple Myeloma","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Confirmed diagnosis of multiple myeloma, currently undergoing active treatment with daratumumab, and under clinical follow-up by the Hematology Department of HU12O.\n* Explicit medical indication for supervised physical activity issued by the responsible hematologist and documented in the medical record.\n* No scheduled hematopoietic stem cell transplantation within the 60 days following the planned start date of the intervention (verified through medical record review).\n* Functional status of ECOG 0-2 (Eastern Cooperative Oncology Group), assessed by a healthcare professional from the Hematology Department, ensuring the ability to perform at least basic and light instrumental activities of daily living, including independent ambulation.\n* Access to a smartphone with stable internet connection, required for monitoring and recording adherence to the intervention.\n* Ability to provide written informed consent, demonstrating understanding of the study's nature, purpose, and procedures.\n\nExclusion Criteria:\n\n* Medical risk contraindicating exercise or breathing techniques:\n\n  +Clinically significant cardiovascular disease, including: decompensated heart failure, acute myocardial infarction within the past 3 months, clinically uncontrolled arrhythmias, unstable angina, acute-phase deep vein thrombosis or pulmonary embolism, pacemakers or cardiac devices whose monitoring parameters contraindicate supervised exercise according to cardiology.\n  * Severe decompensated respiratory disease, such as acute exacerbation of COPD, severe respiratory insufficiency, or persistently low resting oxygen saturation \\\u003C 90% (not correctable).\n* High musculoskeletal or bone risk:\n\n  * Extensive lytic bone lesions, high risk of pathological fracture, or unstable vertebral fracture, documented by imaging or based on the assessment of the Hematology\u002FTraumatology specialist.\n  * Uncontrolled pain that prevents safe participation in an exercise program.\n* Hematologic or systemic conditions contraindicating exercise:\n\n  * Severe anemia: hemoglobin \\\u003C 9 g\u002FdL in women or \\\u003C 8 g\u002FdL in men (latest laboratory test ≤ 14 days).\n  * Active systemic infection contraindicating exercise, fever ≥ 38 °C, or neutropenia \\\u003C 0.5 × 10⁹\u002FL.\n  * Severe cytopenias that, in the opinion of the hematologist, preclude moderate exercise.\n* Functional or procedural limitations:\n\n  * Inability to remain in the supine position for ≥ 5 minutes, required for part of the breathing intervention.\n  * Confirmed pregnancy or reasonable suspicion of pregnancy.\n  * Severe cognitive impairment, major psychiatric disorders, or neurological diseases that limit understanding of the procedures or safe participation.\n  * Significant difficulty understanding the language (spoken or written) that prevents following essential instructions or completing validated questionnaires.",{"count":139,"type":20},[23],"A randomized, parallel, double-blind, controlled, multicenter clinical trial with two intervention arms. Two groups of participants will be included, both receiving a therapeutic exercise intervention and an educational session on the importance of proper breathing over a 6-week period. One of the groups will additionally perform a home-based controlled breathing exercise protocol. Pre- and post-intervention assessments (6 weeks) will be conducted, along with a follow-up evaluation 4 weeks after completion of the intervention.\n\nThe goal is to determine the effectiveness of adding a controlled breathing exercise program to a therapeutic exercise intervention on somatic symptoms in individuals with multiple myeloma",[215,147,28,184,185],"Multiple Myeloma",[217,189,190,191,192,193],"Multiple myeloma","2026-01-15",{"date":220,"type":40},"2026-01-20",{"date":199,"type":20},{"date":223,"type":20},"2026-07",{"name":203,"class":47},{"id":226,"slug":227,"hasResults":11,"nctId":228,"briefTitle":229,"officialTitle":230,"acronym":231,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":16,"minAge":233,"maxAge":234,"enrollmentInfo":235,"targetDuration":4,"studyType":21,"phases":236,"briefSummary":237,"conditions":238,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":250},"100588525","effect-of-visual-feedback-from-the-spirogym-mobile-application-100588525","NCT06942533","Effect of Visual Feedback From the SpiroGym Mobile Application","The Effect of Visual Feedback From the SpiroGym Mobile Application on Expiratory Muscle Strength Training Performance in Patients With Parkinson's Disease","EXPARK","Inclusion Criteria:\n\n* Diagnosis of Parkinsons disease\n* Stable dopaminergic medication (stable dose for at least 1 month)\n\nExclusion Criteria:\n\n* Other neurological disorders\n* Significant cognitive impairment\n* Major psychiatric disorder\n* History of head or neck cancer or previous surgical interventions in the neck region.\n* Illness during the study period","40 Years","80 Years",{"count":111,"type":20},[23],"The previous pilot study showed that two weeks of intensive expiratory muscle strength training (EMST) with SpiroGym was sufficient to significantly improve voluntary peak cough flow (PCF). The improvement was quantitatively comparable to that reported in other intensive EMST studies of longer duration. To explain this rapid improvement, we considered the potential contribution of SpiroGym's visual feedback. We assumed that real-time visual feedback increased training effort compared with conventional EMST performed without immediate feedback.\n\nThe aim of this study is to evaluate the effect of visual feedback provided by the SpiroGym mobile application on performance during expiratory muscle strength training in patients with Parkinson's disease.",[239,28,240],"Parkinson Disease","Telemedicine","2025-11-24",{"date":243,"type":40},"2025-12-01",{"date":245,"type":40},"2025-05-01",{"date":247,"type":20},"2026-07-01",{"name":249,"class":47},"General University Hospital, Prague",2,{"id":252,"slug":253,"hasResults":11,"nctId":254,"briefTitle":255,"officialTitle":256,"acronym":4,"eligibilityCriteria":257,"healthyVolunteers":56,"sex":258,"minAge":17,"maxAge":259,"enrollmentInfo":260,"targetDuration":4,"studyType":21,"phases":262,"briefSummary":263,"conditions":264,"keywords":266,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":48},"100606551","the-effects-of-breathing-exercises-and-music-intervention-during-labor-on-pain-perception-birth-expectations-and-birth-satisfaction-in-primiparous-women-100606551","NCT07177027","The Effects of Breathing Exercises and Music Intervention During Labor on Pain Perception, Birth Expectations, and Birth Satisfaction in Primiparous Women","The Effects of Breathing Exercises and Music Intervention During Labor on Pain Perception, Birth Expectations, and Birth Satisfaction in Primiparous Women: A Randomized Controlled Trial","Inclusion Criteria:Participants were included in the study if they met the following criteria:\n\nVoluntary participation in the study and provision of written informed consent, Being a primiparous pregnant woman, Aged between 18 and 35 years, Gestational age between 38 and 42 weeks, Ability to read and write, No hearing impairment that would prevent listening to music, Planning to deliver vaginally, No respiratory disorders (e.g., asthma, COPD) that would interfere with breathing exercises, No obstetric complications that could affect labor progression (e.g., precipitous labor, prolonged labor), Attendance in antenatal childbirth education classes, including learning breathing exercises and listening to the music pieces planned for the intervention.\n\nNot receiving any labor-inducing medications\n\n\\-\n\nExclusion Criteria: Participants were excluded if they met any of the following:\n\nWithdrawal of consent or unwillingness to continue cooperation at any stage of the study, Refusal to continue with breathing exercises or music intervention during any phase of labor, Undergoing cesarean section due to medical indications despite initial plan for vaginal delivery, Gestational age outside of 38-42 weeks, Development of labor-related complications such as precipitous or prolonged labor during the study.","FEMALE","35 Years",{"count":261,"type":20},90,[23],"This randomized controlled trial aimed to evaluate the effects of music listening and breathing exercises during labor on pain perception, birth expectations, and birth satisfaction among primiparous women. This randomized controlled trial was conducted in the delivery unit of a hospital located in the Inner Aegean Region of Turkey. The study included 90 primiparous pregnant women admitted for vaginal delivery. Participants without visual, auditory, or neurological impairments were included and randomly assigned into three groups: music intervention group, breathing exercise group, and control group (n=30 in each group).\n\nParticipants were randomly assigned to one of three groups (Music Intervention, Breathing Exercise, Control) using a computer-generated randomization sequence. Allocation concealment was ensured by using sealed, opaque envelopes prepared by a researcher who was not involved in participant recruitment or assessment.\n\nIn the music intervention group, participants were introduced to 12 music tracks at 36 weeks of gestation during childbirth preparation classes. Short samples of these tracks were played during the class, and the full tracks were then shared with participants via WhatsApp to encourage regular listening at home.\n\nDuring the prenatal period, participants received regular WhatsApp reminders every few days to listen to the music.\n\nDuring labor, participants were encouraged to listen to music whenever they wished. Additionally, at 4 cm, 6 cm, and 8 cm cervical dilation, all participants in this group listened to their preferred tracks from the playlist for 20 minutes. Pain intensity was measured using the Visual Analog Scale (VAS) before and after each music session.\n\nIn the breathing exercise group, Lamaze breathing techniques were taught during prenatal classes and practiced throughout the labor process. They were encouraged to practice these exercises throughout labor. At 4, 6, and 8 cm cervical dilation, guided breathing exercises were conducted, and pain was assessed using the Visual Analog Scale (VAS) before and after each exercise.\n\nIn the control group, participants received routine maternity care. VAS pain assessments were conducted at the same cervical dilation points (4, 6, and 8 cm), without any additional interventions.\n\nFor all participants, the durations of the first, second, and third stages of labor were recorded and compared across groups. In the postpartum period, the Birth Expectation Scale and Birth Satisfaction Scale were administered.\n\nStudy data included sociodemographic information, VAS pain scores, and scores from the birth expectation and satisfaction scales.",[265,28],"Music Intervention",[267,193,268,269],"Music intervention","Birth","Pregnancy","2025-09-09",{"date":272,"type":40},"2025-09-16",{"date":274,"type":40},"2024-12-03",{"date":276,"type":20},"2025-09-22",{"name":278,"class":47},"Uşak University",{"id":280,"slug":281,"hasResults":11,"nctId":282,"briefTitle":283,"officialTitle":283,"acronym":4,"eligibilityCriteria":284,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":285,"targetDuration":4,"studyType":21,"phases":286,"briefSummary":287,"conditions":288,"keywords":293,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":296,"lastUpdatePostDateStruct":297,"startDateStruct":299,"completionDateStruct":301,"leadSponsor":302,"locationsCount":4},"100605095","the-effects-of-breathing-exercises-on-exam-anxiety-attention-deficit-and-academic-achievement-in-students-preparing-for-university-entrance-exams-100605095","NCT07158060","The Effects of Breathing Exercises on Exam Anxiety, Attention Deficit, and Academic Achievement in Students Preparing for University Entrance Exams","Inclusion Criteria:\n\n* 12th grade students\n* Obtaining consent from both parents and students\n* No language, hearing, intellectual, or psychological disabilities\n* Able to speak and understand Turkish\n* Planning to take the university entrance exam\n* Voluntary participation in the study\n* Selecting two high schools with similar entrance scores for the study\n* Students with high scores on the Westside Test Anxiety Scale\n\nExclusion Criteria:\n\n* Presence of any chronic disease\n* Presence of any heart disease\n* Currently using any psychiatric medication",{"count":87,"type":20},[23],"This study investigates the effects of breathing exercises on exam anxiety, attention, and academic achievement in students preparing for university entrance exams. University entrance exams are significant milestones in students' educational and career paths, often causing high levels of stress and anxiety. These psychological pressures can negatively impact learning, focus, and overall academic performance.\n\nThe study will involve students who volunteer to participate and meet the inclusion criteria. Participants will be guided through structured breathing exercises designed to reduce stress and enhance concentration. The program will be conducted over several sessions, during which students will practice specific breathing techniques under supervision.\n\nPrimary outcomes of the study include the assessment of changes in exam anxiety levels, attention, and academic performance. Secondary outcomes may include students' self-reported stress management skills and overall well-being. Data will be collected using validated questionnaires, attention tests, and academic performance records.\n\nThe purpose of this research is to determine whether regular practice of targeted breathing exercises can provide practical benefits for students, helping them manage anxiety, improve focus, and achieve better academic outcomes. Findings from this study may also offer guidance for educators, parents, and healthcare providers on effective, low-cost interventions to support students during high-pressure academic periods.\n\nParticipants are encouraged to follow instructions carefully and attend all sessions to gain the full benefit of the intervention. Participation is voluntary, and students can withdraw at any time without any negative consequences. Confidentiality of all collected data will be strictly maintained.\n\nBy contributing to this research, participants will help advance understanding of non-pharmacological methods to improve student mental health and academic performance, potentially shaping future educational and stress-management programs.",[289,290,291,28,292],"Academic Acheivement","Attention","Exam Anxiety","Students",[28,291,290,294,292,295],"Academic Achievement","High School Seniors","2025-09-05",{"date":298,"type":40},"2025-09-11",{"date":300,"type":20},"2025-11-01",{"date":201,"type":20},{"name":303,"class":47},"Istanbul University - Cerrahpasa",{"id":305,"slug":306,"hasResults":11,"nctId":307,"briefTitle":308,"officialTitle":309,"acronym":4,"eligibilityCriteria":310,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":311,"targetDuration":4,"studyType":21,"phases":313,"briefSummary":314,"conditions":315,"keywords":316,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":319,"lastUpdatePostDateStruct":320,"startDateStruct":322,"completionDateStruct":324,"leadSponsor":326,"locationsCount":48},"100552367","breathing-exercises-on-lung-function-100552367","NCT06472167","Breathing Exercises on Lung Function","Impact of Breathing Exercises on Lung Function in Chronic Airway Diseases","Inclusion Criteria:\n\n* The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 \\\u003C 80% predicated together with an FEV1\u002FFVC \\\u003C0.70confirm the presence of airflow limitation that is not fully reversible.\n* COPD patients ranging from mild to severe according to GOLD \\[stages I-IV\\].\n* Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).\n* None of the individuals had been engaged in any exercise-training program before participating in the study.\n* Optimized medical therapy according to GOLD \\& Global Initiative for Asthma (GINA)\n* Clinically stable COPD and asthmatic patients (not suffering from a recent respiratory tract infection).\n* All patients are Ex-smoker\n\nExclusion Criteria:\n\n* Age \\\u003C18 years.\n* Pregnancy\n* Current Smokers\n* Patients that are incapable of exercising; unable to understand any questionnaire\n* Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)\n* Neuromuscular disease as Myasthenia gravis, kypho-scoliosis\n* Diaphragmatic Paralysis (paralyzed diaphragm exhibiting abnormal paradoxical movement, i.e., moving in a cranial direction during inspiration).",{"count":312,"type":20},50,[23],"aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.",[28],[193,317,318],"lung function","Chronic airway diseases","2025-05-27",{"date":321,"type":40},"2025-05-29",{"date":323,"type":40},"2024-06-01",{"date":325,"type":20},"2025-12-10",{"name":327,"class":47},"Mansoura University Hospital",{"id":329,"slug":330,"hasResults":11,"nctId":331,"briefTitle":332,"officialTitle":333,"acronym":4,"eligibilityCriteria":334,"healthyVolunteers":11,"sex":258,"minAge":335,"maxAge":336,"enrollmentInfo":337,"targetDuration":4,"studyType":21,"phases":338,"briefSummary":339,"conditions":340,"keywords":4,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":4},"100573062","breathing-exercises-on-depression-in-postmenopausal-women-100573062","NCT06741384","Breathing Exercises on Depression in Postmenopausal Women","Effect of Breathing Exercises on Depression and Sexual Function in Postmenopausal Women","Inclusion Criteria:\n\n* Minimum of 3 years after menopause.\n* Mild to moderate depression.\n* Mild to moderate sexual dysfunction.\n* Their ages will be ranged from 45 to 60 years old.\n* Their BMI will be less than 30 kg\u002Fm2.\n\nExclusion Criteria:\n\n* Prolapse of the pelvic organs.\n* Pelvic tumors.\n* Vaginal infections.\n* Musculoskeletal\u002F neurological limitations to exercise.\n* Psychiatric disorders.\n* Unstable cardiovascular conditions.\n* Diabetes.","45 Years","60 Years",{"count":87,"type":20},[23],"Evaluate the effect of breathing exercises on depression and sexual function in postmenopausal women",[341,342,28],"Postmenopausal","Depressive Symptom","2024-12-18",{"date":345,"type":40},"2024-12-20",{"date":347,"type":20},"2024-12-26",{"date":349,"type":20},"2025-03-25",{"name":351,"class":47},"Middle East University",{"id":353,"slug":354,"hasResults":11,"nctId":355,"briefTitle":356,"officialTitle":357,"acronym":4,"eligibilityCriteria":358,"healthyVolunteers":56,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":359,"targetDuration":4,"studyType":21,"phases":360,"briefSummary":361,"conditions":362,"keywords":364,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":48},"100565453","the-effect-of-breathing-exercise-applied-to-intensive-care-nurses-on-fatigue-and-perceived-stress-100565453","NCT06642376","The Effect of Breathing Exercise Applied to Intensive Care Nurses on Fatigue and Perceived Stress","The Effect of Breathing Exercise Applied to Intensive Care Nurses on Fatigue and Perceived Stress: A Randomized Controlled Study","Inclusion Criteria:\n\n* Working in intensive care for at least 6 months\n* Volunteering to participate in the research\n* Not practicing any complementary therapies during the study, such as breathing exercises, acupuncture, massage therapy, relaxation techniques and yoga, which may be effective on perceived stress and fatigue\n\nExclusion Criteria:\n\n* Having a problem that prevents nasal breathing and prevents breathing exercises\n* Being pregnant\n* Experiencing physical and mental health problems that prevent communication",{"count":87,"type":20},[23],"The aim of this randomized controlled trial was to investigate the effect of breathing exercise on fatigue and stress in intensive care nurses.\n\nHypotheses of the study; H11: The level of perceived stress in nurses practicing breathing exercise is lower than the nurses in the control group.\n\nH12: The level of fatigue is lower in nurses practicing breathing exercise compared to nurses in the control group.\n\nData will be collected in the intervention and control groups with a pre-test data collection form before the intervention. Patients in the intervention group will be given breathing exercises, while patients in the control group will not receive any intervention. In the second week, interim follow-up data will be collected with the data collection form. At the end of the study; data will be collected from the intervention and control groups with post-test data collection forms.",[28,363],"Critical Care Nursing",[365,366,367],"Stress","Nurse","Intensive care","2024-12-04",{"date":370,"type":40},"2024-12-05",{"date":372,"type":40},"2024-10-21",{"date":374,"type":20},"2025-01-15",{"name":376,"class":47},"Kahramanmaraş İstiklal University"]