[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breathing-mouth\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breathing-mouth":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,71,100],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100558686","cardiopulmonary-exercise-testing-and-oscillometry-for-the-evaluation-of-dyspnea-100558686",false,"NCT06554353","Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea","COED","Inclusion Criteria:\n\n* Willingness to perform breathing test\n* Must be able to speak and understand English\n* Referred for Cardiopulmonary Exercise Testing\n\nExclusion Criteria:\n\n* Unable to provide consent or perform oscillometry test","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","OBSERVATIONAL","This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on Cardiopulmonary Exercise Testing in subjects who are experiencing shortness of breath.",[24,25,26,27],"Breathing, Mouth","Lung Function Decreased","Dyspnea","Shortness of Breath","RECRUITING","2026-06-01",{"date":31,"type":32},"2026-06-03","ACTUAL",{"date":34,"type":32},"2024-10-29",{"date":36,"type":20},"2026-11-30",{"name":38,"class":39},"University of Rochester","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":40},"100594337","expression-of-genes-relating-hypertension-and-efficacy-of-4-7-8-breathing-control-on-reducing-blood-pressure-100594337","NCT07018128","Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure","Expression of Genes Relating Hypertension in Thailand and the Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure in Individuals With Hypertension","Study 1:\n\n1. Group of individuals with hypertension\n\n   Inclusion Criteria:\n   * Male or female\n   * Aged between 18-59 years\n   * Of Thai ethnicity\n   * Diagnosed with hypertension, defined as having an SBP of 140 mmHg or higher, or a DBP of 90 mmHg or higher, or having previously been diagnosed with hypertension and currently taking antihypertensive medication\n   * Originally from various regions of Thailand and currently residing in the eastern region\n\n   Exclusion Criteria:\n   * Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure\n   * Has obesity, defined as having a body mass index (BMI) of 30 kg\u002Fm² or higher\n   * Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections\n2. Group of individuals with normal blood pressure\n\nInclusion Criteria:\n\n* Male or female\n* Aged between 18-59 years\n* Of Thai ethnicity\n* Does not have hypertension, defined as having an SBP below 130 mmHg and a DBP below 85 mmHg, with no prior diagnosis of hypertension and no history of taking antihypertensive medication\n* Originally from various regions of Thailand and currently residing in the eastern region\n\nExclusion Criteria:\n\n* Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure\n* Has obesity, defined as having a body mass index (BMI) of 30 kg\u002Fm² or higher\n* Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections\n\nStudy 2:\n\nInclusion Criteria:\n\n* Male or female, aged 35-59 years\n* Diagnosed with hypertension, with blood pressure levels above the normal range, defined as SBP of 130 mmHg or higher, or DBP of 85 mmHg or higher, and currently taking medication\n* Originally from various regions of Thailand and currently residing in the eastern region\n* Able to communicate effectively\n\nExclusion Criteria:\n\n* Has respiratory diseases, cardiovascular diseases, cerebrovascular disease, kidney disease, cancer, or immune-related conditions such as allergies, autoimmune diseases (e.g., SLE), immunodeficiency, or rheumatoid arthritis\n* Is obese, defined as having a body mass index (BMI) of 30 kg\u002Fm² or higher\n* Has a fever or is currently infected, such as with COVID-19, the flu, or other infectious diseases\n* Is currently pregnant, breastfeeding, or has a history of pregnancy within the 6 months prior to participating in the study",true,"59 Years",{"count":51,"type":20},200,"INTERVENTIONAL",[54],"NA","This study consists of two sub-studies. Study 1 investigates gene expression related to the development of hypertension in Thailand, and Study 2 examines the effectiveness of the 4-7-8 breathing technique in reducing blood pressure in individuals with hypertension.",[57,24],"Genetic Predisposition to Disease",[59,60,61],"Gene","Blood pressure","Breathing","2026-05-08",{"date":64,"type":32},"2026-05-11",{"date":66,"type":32},"2024-10-01",{"date":68,"type":20},"2026-09-30",{"name":70,"class":39},"Burapha University",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":52,"phases":80,"briefSummary":81,"conditions":82,"keywords":87,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":40},"100624575","combined-acupressure-effects-on-post-thoracotomy-pain-and-lung-volume-100624575","NCT07411417","Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume","The Effects of Acupressure Combination on Post-Thoracotomy Pain and Lung Volume During Rest, Breathing-Coughing Exercises: A Randomized Controlled Study","Inclusion Criteria:\n\n* Underwent thoracotomy\n* Undergoing thoracic surgery for the first time\n* Classified as ASA (American Society of Anesthesiology) physical status I, II and III\n* Presence of a drain upon admission to the intensive care unit\n* Conscious, oriented, and cooperative\n* Provided verbal and written informed consent after receiving information about the study\n\nExclusion Criteria:\n\n* Intubated\n* Persistent anxiety before the surgery\n* Diagnosed with panic disorder\n* Chemotherapy within the last 6 months\n* Diagnosed psychiatric illness or mental health problems\n* Presence of edema\n* Intraoperative or postoperative complications\n* Non-Turkish speaking, or presence of hearing or visual impairment\n* Body mass index (BMI) greater than 30\n* Participation in another clinical trial during the study period",{"count":79,"type":20},80,[54],"Pain is a subjective, sensory and emotionally unpleasant experience resulting from real or hidden injuries in tissues. The pain experience is a subjective and unique experience in physiological and psychological terms and is the first negative sensory experience of the patient after the surgical procedure. Thoracotomy is an invasive surgical incision that causes severe postoperative pain due to the negative effect on the ribs, muscles and peripheral nerves. During thoracic surgery, anatomical lung resection is performed through posterolateral thoracotomy. Surgical incision during thoracotomy surgery is the most severe cause of postoperative pain. Epidural analgesia, peripheral nerve block and systematic treatment methods are used in post-thoracotomy pain management. Opioid use is frequently preferred in post-thoracotomy pain management. Although thoracotomy pain can mostly be controlled with opioid analgesics, excessive use of opioids may lead to respiratory suppression, constipation, suppression of cough, nausea, vomiting and many other possible side effects. Ineffective postoperative pain management may lead to postoperative complications such as increased cardiac workload, prolonged pulmonary rehabilitation and delayed wound healing. The use of holistic non-drug pain relief methods is vital in reducing the need for opioid analgesics and the risk of possible side effects in early postoperative pain management.",[83,24,84,85,86],"Pain, Acute","Relaxation; Diaphragm","Cough","Lung Volume",[88,89,90,86],"Thoracotomy after Pain","Acupressure","Pain","2026-02-11",{"date":93,"type":32},"2026-02-13",{"date":95,"type":32},"2025-01-06",{"date":97,"type":20},"2027-01-06",{"name":99,"class":39},"Özgül Aydemir",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":48,"sex":16,"minAge":107,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":52,"phases":110,"briefSummary":111,"conditions":112,"keywords":115,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":40},"100515167","mouth-odor-on-preventing-pneumonia-by-oral-frailty-100515167","NCT05987982","Mouth Odor on Preventing Pneumonia by Oral Frailty","Mouth Odor as a Precision Care Indicator for Preventing Pneumonia Among Middle-aged and Older Adults With Oral Frailty","Inclusion Criteria:\n\n* Age ≥ 50 years old,\n* Alert and oriented,\n* With sufficient comprehension and cooperation,\n* Willing to participate in oral assessment.\n\nExclusion Criteria:\n\n* Patients who score below 5 on the General Practitioner Assessment of Cognition (GPCOG),\n* Patients with oral treatments such as oral cancer treatment,\n* Patients with oral treatments such as periodontal disease treatment.","50 Years",{"count":109,"type":20},304,[54],"This research plan aims to first collect data on the oral function and oral hygiene status of the elderly population in the community and to understand the normal model of oral frailty among the older adults in the community. Subsequently, a comparison will be made between the oral status of hospitalized patients and the community-dwelling elderly population. The goal is to verify whether oral odor can be used as an objective biological indicator following intervention.",[24,113,114],"Pneumonia","Frailty",[116,117,118,119,120],"mouth odor","pneumonia","oral bacteria","oral frailty","oral management rehabilitation","2024-07-20",{"date":123,"type":32},"2024-07-23",{"date":125,"type":32},"2023-08-14",{"date":127,"type":20},"2026-07-31",{"name":129,"class":39},"National Cheng-Kung University Hospital"]