[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breathing-pattern-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breathing-pattern-disorder":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,52,77,101,128],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100642831","breathlessness-perceptions-within-respiratory-diseases-100642831",false,"NCT07648082","Breathlessness Perceptions Within Respiratory Diseases","Exploring Differences in Breathlessness Perceptions Within Respiratory Diseases","BiRD","Inclusion Criteria:\n\n* • Aged 18 or over up to 100\n\n  * Known respiratory diagnosis\\* OR Healthy control\\*\\*\n  * Ongoing symptoms of breathlessness defined as ≥2 MRC dyspnoea scale\n  * Able to communicate in English\n  * Able to attend two study visits\n  * Able to provide written informed consent\n\n    * Known respiratory diagnosis could include, but is not limited to, COPD, Asthma, Bronchiectasis or ILD.\n    * Healthy controls are required to have an absence of a functionally limiting condition such as respiratory, cardiovascular, or musculoskeletal.\n\nExclusion Criteria:\n\n* • Unstable disease or undergoing investigations for unexplained symptoms\n\n  * Undergone a surgery within past six weeks\n  * Contraindications for exercise outlined by ACSM guidelines (Unstable CVD, hypertension etc)\n  * BMI ≥ 35kg\u002Fm2\n  * Unable to communicate in English\n  * Unable to provide written informed consent\n  * Unable to abstain from smoking for 8 hours prior to testing",true,"ALL","18 Years","100 Years",{"count":22,"type":23},75,"ESTIMATED","OBSERVATIONAL","Breathlessness is a complex symptom that results in poor quality of life, increased hospitalisations and increased mortality. Breathlessness is influenced by physiological, psychological and functional factors but these are poorly explored. There are also unexplored phenomenon's such as breathing pattern. Therefore, this study aims to understand the influences of physiology, psychology, function and breathing pattern on health related quality of life in those with a respiratory disease compared to healthy controls. This project is a cross-sectional cohort study including those with a known respiratory disease and experiencing breathlessness, compared to non-breathless healthy controls. The investigators will measure your physiology through spirometry (a breathing test that tells us about their lung function), psychology through questionnaires, function through an exercise test and breathing pattern using opto-electrictronic plethysmography (markers are placed on your chest to see how participants breathe while exercising). This will be conducted over two visits. The investigators will recruit participants from clinics at the University Hospitals of Leicester NHS Trust. The investigators are aiming to recruit 50 participants with a respiratory disease and 25 healthy controls. The results of this study will help us understand breathlessness in more detail in order to be able to develop better treatments.",[27,28,29,30,31],"Chronic Obstructive Pulmonary Disease (COPD)","Asthma (Diagnosis)","Interstitial Lung Disease (ILD)","Bronchiectasis","Breathing Pattern Disorder",[33,34,35,36,37,38],"Breathlessness","OEP","Cardiopulmonary Exercise Testing","Respiratory diseases","Heart rate variability","Breathing patterns","RECRUITING","2026-06-10",{"date":42,"type":43},"2026-06-15","ACTUAL",{"date":45,"type":43},"2025-06-06",{"date":47,"type":23},"2026-07-01",{"name":49,"class":50},"University Hospitals, Leicester","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":51},"100524072","optimuscle---improving-respiration-by-optimising-muscle-function-100524072","NCT06103955","OptiMuscle - Improving Respiration by Optimising Muscle Function","Improving Outcomes in Dysfunctional Breathing Through the Optimization of Muscle Function (OptiMuscle)","OptiMuscle","Inclusion Criteria:\n\n* Ability to stand and walk independently\n* History of breathing difficulties, such as breathlessness and difficult or laboured breathing for at least previous 6 months.\n* Clinical diagnosis of dysfunctional breathing, sometimes referred to as breathing pattern disorder.\n* If participants have co-existing respiratory problems, e.g. asthma, these should not be felt (in the opinion of the referring clinician) to be the cause of the current symptoms of breathlessness.\n\nExclusion Criteria:\n\n* Inability to speak and understand English sufficient to read and understand the information sheet and sign the consent form.\n* BMI \\>34\n* Currently receiving active treatment for dysfunctional breathing\n* Received treatment for acute lower respiratory tract infection or asthma exacerbation with last 4 weeks\n* Significant respiratory co-morbidity (i.e. where the major respiratory diagnosis is not asthma)",{"count":61,"type":23},10,"INTERVENTIONAL",[64],"NA","The primary aim will be to understand whether a digital breathing biofeedback system can improve the outcomes of physiotherapist guided breathing retraining.",[67,31],"Dysfunctional Breathing","2026-04-29",{"date":70,"type":43},"2026-05-06",{"date":72,"type":43},"2024-03-01",{"date":74,"type":23},"2026-07-31",{"name":76,"class":50},"University of Salford",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":87,"conditions":88,"keywords":89,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":51},"100634738","the-physiotherapy-assessment-of-breathing-pattern-disorder-100634738","NCT07543588","The Physiotherapy Assessment of Breathing Pattern Disorder","An Evaluation of Physiotherapy Assessment; A Mixed Methods Study to Evaluate the Physiotherapy Assessment of Breathing Pattern Disorder","PHAB","Inclusion Criteria (Breathing Pattern Disorder group)\n\n* Adults aged above 18 years\n* Outpatient referrals for 'unexplained breathlessness' or possible breathing pattern disorder\n* Primary BPD (no other significant respiratory or cardiology diagnosis)\n* Secondary BPD (patients with a diagnosis of asthma)\n* Able to complete up to four sessions of outpatient physiotherapy intervention Exclusion Criteria\n* Patients with a respiratory diagnosis including COPD, ILD, Bronchiectasis and Cystic Fibrosis or structural heart disease\n* Pregnancy\n* Unable to give informed consent\n* Anyone currently participating in pulmonary\u002Fcardiac rehabilitation\n* Anyone receiving specialist ENT speech and language therapy for Upper airway symptoms",{"count":86,"type":23},150,"This study aims to evaluate a clinical tool called the Breathing Pattern Assessment Tool (BPAT), which is used by physiotherapists to assess breathing pattern disorder (BPD). BPD is a condition where breathing is inefficient or out of sync with the body's needs, leading to symptoms such as breathlessness.\n\nThe study will investigate whether the BPAT is a reliable and accurate way to identify and assess BPD, and whether it can be used to monitor changes over time, particularly following physiotherapy treatment. It will also compare BPAT scores with other commonly used questionnaires that measure breathlessness and breathing symptoms.\n\nParticipants will include patients with BPD, patients with asthma, and healthy individuals. Patients with BPD will attend physiotherapy sessions as part of their usual care, during which their breathing will be assessed using the BPAT at different time points, including before and after treatment. Healthy participants will attend a single assessment visit, and asthma participants' data will be collected from routine clinical care.\n\nThe study will also explore whether BPAT scores change following treatment and whether these changes reflect improvements reported by patients and clinicians.\n\nIn addition, a small number of patients and physiotherapists will be invited to take part in interviews to share their experiences of the assessment process and treatment. This will help understand whether the BPAT is acceptable and useful in clinical practice.\n\nOverall, this study aims to improve how breathing pattern disorder is assessed and monitored, which may help guide better treatment for patients in the future.",[31,33],[33,31,90,91],"Physiotherapy","Assessment","2026-04-28",{"date":94,"type":43},"2026-05-05",{"date":96,"type":43},"2024-12-10",{"date":98,"type":23},"2026-05-01",{"name":100,"class":50},"Royal Brompton & Harefield NHS Foundation Trust",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":62,"phases":110,"briefSummary":111,"conditions":112,"keywords":113,"overallStatus":118,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100600966","the-effect-of-inspiratory-muscle-training-on-breathing-pattern-and-functionality-in-patients-with-chronic-heart-failure-100600966","NCT07104357","The Effect of Inspiratory Muscle Training on Breathing Pattern and Functionality in Patients With Chronic Heart Failure.","The Effect of Inspiratory Muscle Training on Dysfunctional Breathing and Functional Ability in Patients With Chronic Heart Failure. A Study Protocol for a Randomized Controlled Trial","Inclusion Criteria:\n\n* adults aged ≥ 18 years\n* diagnosis of heart failure within the previous three to twelve months\n* current outpatients in a stable optimal medical regimen for at least 3 months\n* able to perform inspiratory muscle training\n* clinically stable, without hospital admission in the previous 3 months and without participation in any other training program in the previous 6 months\n\nExclusion Criteria\n\n* unstable angina\n* recent acute myocardial infarction\n* uncontrolled hypertension\n* valve disease\n* peripheral arterial disease\n* 6MWT assessment of less than 300 meters\n* previous pulmonary disease (forced vital capacity \\\u003C80% of predicted and\u002For forced expiratory volume in 1 s \\\u003C70% of predicted)\n* history of exercise-induced asthma\n* smokers",{"count":109,"type":23},18,[64],"The effect of inspiratory muscle training on breathing pattern and functionality in patients with chronic heart failure.",[31],[114,115,116,117],"inspiratory muscle training","dysfunctional breathing","functional ability","chronic heart failure","NOT_YET_RECRUITING","2025-07-28",{"date":121,"type":43},"2025-08-05",{"date":123,"type":23},"2025-08-15",{"date":125,"type":23},"2026-10-15",{"name":127,"class":50},"University of West Attica",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":136,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":138,"conditions":139,"keywords":142,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":159},"100575744","dysfunctional-breathing-in-post-covid-19-condition-100575744","NCT06776263","Dysfunctional Breathing in Post COVID-19 Condition.","Dysfunctional Breathing in Patients With Post COVID-19 Condition","DB-PCC","Inclusion Criteria:\n\n* Patients that state that they have persistent respiratory problems, have 2 or higher on mMRC scale or 23 and over on the Nijmegen scale will be included.\n\nExclusion Criteria:\n\n* Not able to perform the measurements because of cognitive or physical impairments, ongoing intervention of breathing exercises.",{"count":137,"type":23},200,"The goal of this observational study with a cross-sectional design is to investigate what signs, symptoms and assessment which can describe and explain dysfunctional breathing in patients with post COVID-19 condition. The main question aims to answer which measurements can identify and asses dysfunctional breathing in patients with post COVID-19 condition?\n\nParticipants for this study will be recruited from the ReCov cohort will be evaluated with diffrent measurments and questionnaires.",[140,67,31,141],"Post COVID-19 Condition (PCC)","Post-Acute COVID-19 Syndrome",[143,144,145,146,147,148,149],"Respiration","Dyspnea","Signs and Symptoms, Respiratory","Hyperventilation","Outcome Assessment, Health Care","Patient Outcome Assessment","Surveys and Questionnaires","2025-02-13",{"date":152,"type":43},"2025-02-14",{"date":154,"type":43},"2025-01-15",{"date":156,"type":23},"2026-06-30",{"name":158,"class":50},"Karolinska Institutet",2]