[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breathing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breathing":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,64,94],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100640372","phase-resolved-functional-lung-mri-and-oscillometry-for-the-observation-of-healthy-lung-function-100640372",false,"NCT07614685","Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function","PROOF","Inclusion Criteria:\n\n* Age 18 years or older\n* Ability to provide consent\n* Willingness to perform MRI and breathing test\n* Must be able to speak and understand English\n\nExclusion Criteria:\n\n* Pregnant\n* Unable or willing to provide consent or perform the required maneuvers for testing.",true,"ALL","18 Years",{"count":20,"type":21},20,"ESTIMATED","OBSERVATIONAL","This study will examine the relationship of airways resistance measured by oscillometry with ventilation defects measured by Phase Resolved Functional Lung (PREFUL) MRI in healthy human subjects.",[25,26,27,28],"Breathing","Lung Function Decreased","MRI Imaging","Healthy","NOT_YET_RECRUITING","2026-05-20",{"date":32,"type":33},"2026-05-29","ACTUAL",{"date":35,"type":21},"2026-07-01",{"date":37,"type":21},"2028-01-01",{"name":39,"class":40},"University of Rochester","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":41},"100620337","body-composition-related-evaluation-of-airway-tone-and-hyper-reactivity-using-oscillometry-100620337","NCT07356310","Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry","BREATH-OSC","Inclusion Criteria:\n\n* Willingness to perform breathing test\n* Must be able to speak and understand English\n* Referred for Methacholine Challenge Test\n\nExclusion Criteria:\n\n* Unable to provide consent or perform oscillometry test",{"count":50,"type":21},100,"This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on methacholine challenge testing and whether these findings are associated with body habitus,",[25,26,53,54],"Asthma (Diagnosis)","Obesity","RECRUITING","2026-04-07",{"date":58,"type":33},"2026-04-13",{"date":60,"type":33},"2026-02-17",{"date":62,"type":21},"2027-11-01",{"name":39,"class":40},{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":4,"eligibilityCriteria":69,"healthyVolunteers":16,"sex":17,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":4,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":83,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":41},"100562717","the-effects-of-cervical-and-thoracic-manipulation-therapy-applied-to-weightlifting-athletes-100562717","NCT06606795","The Effects of Cervical and Thoracic Manipulation Therapy Applied to Weightlifting Athletes","Inclusion Criteria:\n\n* Being a weightlifter,\n* Having asymptomatic dysfunction in the cervical and thoracic spine,\n* Not having received any manipulative treatment in the last six months,\n* Individuals who do not have a condition that prevents chiropractic manipulation treatment will be included in the study.\n\nExclusion Criteria:\n\n* Having had an injury related to the musculoskeletal system in the upper and lower extremities in the last month,\n* Having any neurological and psychiatric disorders,\n* Having cervical disc herniations,\n* Having a disorder related to the cardiac and respiratory systems,\n* Having an infectious, rheumatological, metabolic and endocrinological disorder,\n* Having dislocation, osteoporosis, ankylosing spondylitis, discopathy, rheumatoid arthritis,\n* Taking anticoagulant treatment,\n* Individuals who have recently undergone an operation involving the cervical and thoracic regions will not be included in the study.","13 Years","35 Years",{"count":73,"type":21},40,"INTERVENTIONAL",[76],"NA","The effects of manipulation therapy on the autonomic nervous system have been examined in the literature and while no sympathetic or parasympathetic changes were found after upper thoracic manipulation, a decrease in sympathetic data was observed after lower thoracic manipulation and an increase in parasympathetic data was observed. On the other hand, a different study found that thoracic manipulation did not cause any changes such as an increase or decrease in the autonomic nervous system. Therefore, although there are uncertainties in the autonomic role of manipulation therapy, its effect on respiration is intriguing when positive studies are considered.\n\nIn a study aiming to evaluate the effect of thoracic manipulation on respiratory function, segmental manipulation treatment was applied to healthy individuals by detecting the vertebrae in the thoracic region where normal joint movements were lost, and it was determined that the respiratory functions of the manipulation group improved significantly compared to the group that did not receive treatment. In another study conducted on healthy individuals, the subjects were divided into manipulation group, exercise and manipulation group and control groups. At the end of the study, it was determined that there was a significant increase in the respiratory functions of the participants in the manipulation group, while an additional increase was observed in the group combined with exercise, but this was not significant. No change was observed in the control group.\n\nWhen the literature is examined, it is noteworthy that the effects of manipulation treatments on respiration remain unclear, and especially the inadequacy of studies on Olympic-style weightlifters and the ongoing search for increasing athletic performance in this area.\n\nThis study aims to examine the effects of cervical and thoracic manipulation treatments on respiratory muscle strength, respiratory functions and cervical and thoracic region joint range of motion in weightlifters.\n\nThe main question it aims to answer is:\n\n\\- Is cervical and thoracic manipulation therapy applied to Olympic style weightlifters effective on respiration?",[79,25,80,81,82],"Weightlifting","Breath Tests","Athlete","Spinal Manipulation",[79,84,25,82,81],"Chiropractic","2024-09-19",{"date":87,"type":33},"2024-09-23",{"date":89,"type":21},"2024-10-04",{"date":91,"type":21},"2025-04-01",{"name":93,"class":40},"Selcuk University",{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":101,"targetDuration":4,"studyType":74,"phases":103,"briefSummary":104,"conditions":105,"keywords":108,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":41},"100554037","respiratory-rehabilitation-based-on-eccentric-exercice-on-treadmill-after-thoracic-surgery-100554037","NCT06493877","Respiratory Rehabilitation Based on Eccentric Exercice on Treadmill After Thoracic Surgery","Respiratory Rehabilitation Based on Eccentric Exercice on Treadmill After Thoracic Surgery: a Randomized Clinical Trial","Inclusion Criteria:\n\n* Subjects \\>18 years.\n* Thoracic surgery in the previous 75 days\n* Present dyspnea grade 2 - 3 on the mMRC scale.\n* Cognitive and functional level sufficient to understand, learn and carry out the exercise program.\n* Not have contraindications to perform physical training.\n* Active collaborators.\n\nExclusion Criteria:\n\n* Severe intolerance to exertion due to untreated cardiac arrhythmias, ischemia during low intensity exercise (anginas unstable), severe pulmonary hypertension, heart failure (NYHA III or IV)\n* Pulmonary embolism with anticoagulant treatment less than 5 days.\n* Recent cardiovascular events such as congestive heart failure, angioplasties or cardiac surgeries of less than four weeks' duration, valvular alterations requiring surgical correction, myopericarditis, ventricular arrhythmias caused by exercise.\n* Kidney failure requiring dialysis.\n* Patients with uncontrolled bronchospasm due to intrinsic asthma.\n* Patients undergoing post-surgery chemotherapy treatment.\n* Adverse effects that occurred during the development of the treatment.",{"count":102,"type":21},57,[76],"Thoracic surgeries are frequent and pulmonary rehabilitation is essential, since one of the problems that these patients present is dyspnea when performing aerobic exercise, which limits improvement and in some cases causes them to abandon physical exercise. Thanks to carrying out a correct effort retraining program, combining respiratory physiotherapy with therapeutic exercise, patients with respiratory pathologies manage to improve lung capacity and ventilatory mechanics, increase muscle strength and aerobic resistance, prevent long- term complications, reduce fatigue and, ultimately, improve your quality of life.\n\nLikewise, it is important to find the most appropriate type of muscular work that produces more benefits in the short and medium term to optimize our resources.The objective of the study is to demonstrate the effectiveness of eccentric training in patients who have undergone thoracic surgery, in terms of strength, lung capacity, functionality and quality of health in the short and medium term.\n\nFor this purpose, a randomized clinical trial has been designed, with a blinded examiner, following the CONSORT guideline for clinical trials and the ethical principles of the Declaration of Helsinki. A total sample of 57 subjects has been estimated. The study is aimed at patients after scheduled thoracic surgery. A program of 12 group sessions spread over 4 weeks will be carried out. Each of them will last 75 minutes and will include strength and respiratory physiotherapy exercises, common to all subjects.\n\nAerobic interval training will depend on the group assigned: treadmill with negative slope (experimental group), treadmill with positive slope (control group 1) or cycle ergometer (control group 2). On the first and last day of treatment, as well as one month after completing the intervention, the following variables will be measured: thickness, cross-sectional area and ultrasound intensity of the rectus femoris; diaphragmatic excursion and thickness; 6 minute walk test; Borg scale; maximum respiratory pressures; sit-to-stand test; grip strength in both hands; spirometric assessment of FEV1 and SF-12 health quality questionnaire. a",[106,25,107],"Thoracic Surgery","Muscle",[109,110,111],"\"thoracic surgery\"","\"eccentric training\"","\"pulmonary rehabilitation\"","2024-07-09",{"date":114,"type":33},"2024-07-11",{"date":116,"type":21},"2024-09",{"date":118,"type":21},"2027-09",{"name":120,"class":40},"Universidad Europea de Madrid"]