[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"burn-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:burn-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100639271","mesenchymal-stem-cells-in-the-treatment-of-burn-wounds-100639271",false,"NCT07580755","Mesenchymal Stem Cells in the Treatment of Burn Wounds","A Randomized Controlled Study on the Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Extensive Burns","Inclusion Criteria:\n\n1. Voluntary participation and signing of the informed consent form;\n2. Burn patients, subjects requiring autologous skin grafting;\n3. Age 18 to 65 years old, gender not restricted;\n4. During this clinical study, single person, single donor skin area (lateral thigh or trunk) treatment;\n5. Skin burn area \\\u003C 30% of total body surface area (TBSA);\n6. The donor skin area is the first time for donation, and the donor skin area is medium-thick skin (thickness approximately 0.4mm);\n7. The area of the excised skin flap ≥ 90 cm2;\n8. Able to cooperate with this study protocol and accept regular postoperative follow-up visits.\n\nExclusion Criteria:\n\n1. Those allergic to sodium alginate (gel component);\n2. Electric shock injuries, chemical burns, radiation injuries or combined with other traumas;\n3. Subjects with severe systemic diseases (judged by the researchers);\n4. Subjects with uncontrolled hypertension or diabetes (judged by the researchers);\n5. Pregnant or lactating women;\n6. Subjects whose condition may affect the study assessment or require the concurrent use of medical treatments that may affect the efficacy assessment;\n7. Subjects with acute or chronic kidney diseases, renal failure or serum creatinine level = 1.5 times the upper limit of normal value;\n8. Subjects with acute or chronic liver diseases, total bilirubin, alanine aminotransferase, aspartate aminotransferase = 2.0 times the upper limit of normal value;\n9. Subjects with a history of malignant tumors;\n10. Subjects who have participated in other clinical studies for less than 3 months;\n11. Subjects with mental disorders and without self-awareness, unable to express clearly;\n12. Subjects using immunosuppressants and those who have been using corticosteroids for a long time (more than 1 month) (excluding local application);\n13. Subjects with infectious diseases (any one of the four items positive in the test);\n14. Subjects with other severe systemic diseases;\n15. Other subjects that the researchers consider not eligible for inclusion.","ALL","18 Years","65 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","Burn patients were randomly divided into the low-dose stem cell gel group, the high-dose stem cell gel group, and the placebo group (with only the gel), and received the same treatment under the same conditions simultaneously.",[27,28],"Burn Injury","Burn Patients","RECRUITING","2026-05-05",{"date":32,"type":33},"2026-05-12","ACTUAL",{"date":35,"type":21},"2026-04-27",{"date":37,"type":21},"2028-12-31",{"name":39,"class":40},"The First Affiliated Hospital of Xinxiang Medical College","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":4},"100622570","comfort-communication-model-intervention-for-burn-pain-and-pain-anxiety-100622570","NCT07385339","Comfort Communication Model Intervention for Burn Pain and Pain Anxiety","The Effect of a Nursing Intervention Based on the Comfort Communication Model on Pain and Pain Anxiety in Outpatient Burn Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Be 18 years of age or older,\n* Patients with at least three dressing experiences\n* Patients with 2nd and 3rd degree burns\n* No difficulty communicating in Turkish,\n* No hearing problems or cognitive impairment,\n* No additional mental disorders,\n* Willingness to cooperate,\n* No additional mental disorders,\n* Ability to perform self-care,\n* Patients who voluntarily agreed to participate in the study\n\nExclusion Criteria:\n\n* First-time burn care dressing\n* Having a first-degree burn\n* Actively receiving inpatient treatment\n* Having a neurological or psychiatric condition that prevents reading and understanding data collection tools\n* Having difficulty speaking\u002Funderstanding Turkish",{"count":50,"type":21},62,[24],"This single-center, randomized controlled trial will evaluate the effect of a nursing intervention based on the COMFORT Communication Model on procedural pain and burn-specific pain anxiety in adult outpatient burn patients undergoing routine dressing changes at the Adult Burn Center Outpatient Unit of Ankara Bilkent City Hospital. Burn dressing changes are frequently perceived as one of the most painful non-surgical procedures, and repeated exposure to wound care may contribute to anticipatory anxiety and stress, potentially creating a reinforcing cycle in which anxiety amplifies pain and pain increases anxiety. In outpatient burn care, effective nurse-patient communication may play a critical role in improving comfort, supporting coping, and enhancing engagement in ongoing treatment.\n\nEligible participants will be adults aged 18 years and older with second- or third-degree burns who have experienced at least three prior dressing changes, can communicate in Turkish, and have no major hearing or cognitive impairment or comorbid psychiatric\u002Fneurological condition that would prevent understanding of the study procedures. Participants who request withdrawal, require hospitalization during follow-up, or miss two consecutive intervention sessions will be withdrawn from the study. The required minimum sample size was estimated as 62 patients (31 per group) based on power analysis (effect size f=0.30; 80% power).\n\nAfter providing written and verbal informed consent, participants will be randomly assigned (simple randomization using Random Allocation Software) to either the COMFORT-based communication intervention group or the usual care control group. Data will be collected face-to-face in a quiet and private environment during dressing visits. At the initial visit, participants in both groups will complete a sociodemographic and burn-related information form and baseline assessments. Pain intensity will be evaluated using a Verbal Rating Scale and a Numeric Rating Scale, and pain anxiety will be assessed using the Burn-Specific Pain Anxiety Scale; perceived stress will also be measured.\n\nThe intervention will be delivered by a wound care nurse during three consecutive dressing sessions. Each session is structured to last approximately 10 minutes and uses specific components of the COMFORT Communication Model tailored to the dressing-change context. In Session 1, the focus is on establishing trust, providing clear information, and supporting patient control through Connection\u002FCommunication, Orientation and opportunity, and Relating strategies (e.g., explaining the procedure step-by-step, checking understanding, offering supportive options, and inviting the patient to signal if they want pauses). In Session 2, the focus shifts to creating space for emotions and strengthening supportive openings using Mindful communication, Openings, and Family components (e.g., exploring how the prior session felt, inviting expression of concerns, and identifying supportive persons). In Session 3, communication emphasizes personalization, meaning-making, and teamwork by integrating Relating, Team, and Meaning-focused prompts (e.g., reflecting on what was most helpful, supporting adaptive coping, and, if appropriate, facilitating communication with the clinical team). Throughout all sessions, routine wound care will continue as standard practice in both groups.\n\nOutcomes will be assessed repeatedly across the three dressing sessions. Pain and pain anxiety will be assessed before each dressing, and follow-up assessments will be repeated approximately 30 minutes after the dressing procedure. The primary objective is to determine whether COMFORT model-based nursing communication reduces procedural pain intensity and burn-specific pain anxiety compared with usual care during outpatient dressing changes. A secondary objective is to evaluate whether the intervention reduces perceived stress across sessions. Statistical analyses will include appropriate descriptive and repeated-measures comparisons to examine group differences over time.",[28,54,55],"Pain Management","Nursing Interventions",[57,58,59,60,61,62],"burn patients","dressing change","pain","pain anxiety","Comfort communication model","nursing intervention","NOT_YET_RECRUITING","2026-02-27",{"date":66,"type":33},"2026-03-02",{"date":68,"type":21},"2026-02-17",{"date":70,"type":21},"2026-06-10",{"name":72,"class":40},"Baskent University",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":4},"100611751","hologram-burn-dressing-on-pain-anxiety-fear-patient-satisfaction-and-physiological-parameters-100611751","NCT07244653","Hologram Burn Dressing on Pain, Anxiety, Fear, Patient Satisfaction, and Physiological Parameters","Effect of Hologram Application During Burn Dressing on Pain, Anxiety, Fear, Patient Satisfaction, and Physiological Parameters: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Between the ages of 18 and 65,\n* Able to read, write, and speak Turkish,\n* Not participating in any other clinical trials at the same time,\n* Patients who were decided to be admitted to a burn unit,\n* No infected cases,\n* Patients who did not undergo minor and\u002For major surgical procedures that could affect the wound healing process,\n* No chronic illness other than burns,\n* No cognitive, sensory, or other problems that would prevent verbal communication and understanding the information given,\n* Second-degree burn with a total body surface area (TBSA) of less than 20%; Patients were included in the study if their burn rate was below 15% (20% in Grade 2 patients; sedation was required in Grade 3 patients with burn rates above 15%),\n* 2nd and 3rd degree burns in the granulation stage (2nd and 3rd degree burns requiring granulation treatment and experiencing high pain),\n* No burns on the head, ears, or face,\n* Daily dressing changes with a frequency of 1-15 dressing changes,\n* No complaints that would prevent participation in the study, such as respiratory problems,\n* No vision or hearing problems.\n\nExclusion Criteria:\n\n* Those with a pain intensity between 8 and 10 points (sedation is required when the pain intensity is 8 or higher),\n* Those under the influence of various non-pharmacological treatment methods that may affect pain,\n* Patients requiring advanced surgical procedures such as fasciotomy, escharotomy, or amputation,\n* Patients receiving sedation during the dressing,\n* Patients interrupting the hologram video during the dressing,\n* First-degree burns,\n* Those with neurological, psychological, or psychiatric illnesses,\n* Patients receiving sedation during the dressing,\n* Patients interrupting the hologram video during the dressing",{"count":81,"type":21},70,[24],"Burn injuries are a significant global health problem, leading to serious physical, psychological, and social challenges for affected individuals. The literature emphasizes that dressing changes are among the most painful and anxiety-provoking procedures, negatively impacting treatment adherence and patient well-being. Although pharmacological methods are used to alleviate pain and anxiety, they are often insufficient due to potential side effects and addiction risks.\n\nIn recent years, advancements in digital technologies-particularly virtual reality (VR), augmented reality (AR), and hologram applications-have offered promising distraction-based approaches. Hologram technology, through three-dimensional and interactive visuals, can divert the patient's attention from traumatic stimuli, thereby reducing pain, anxiety, and fear in an innovative way. However, there is limited scientific evidence regarding the use of hologram applications during burn dressing changes.\n\nThis study aims to examine the effects of hologram applications on pain, anxiety, fear, patient satisfaction, and physiological parameters during burn dressing procedures. The research will be conducted at Erzurum City Hospital Burn Center, with a total of 70 patients assigned to experimental and control groups using simple randomization. Data collection tools will include the Visual Analogue Scale (VAS), the State-Trait Anxiety Inventory (STAI), the Burn Specific Pain Anxiety Scale, satisfaction and fear VAS assessments, and physiological parameter recording forms. The study will be carried out between November 2025 and May 2026. The results are expected to provide evidence-based insights into the feasibility and effectiveness of hologram technology as a non-pharmacological, innovative intervention in burn care.",[85,86,28,87],"Anxiety","Burn Pain","Fear","2025-12-26",{"date":90,"type":33},"2025-12-29",{"date":92,"type":21},"2025-12-31",{"date":94,"type":21},"2026-07-20",{"name":96,"class":40},"Gamze BULUT"]