[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"burnout-healthcare-workers\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:burnout-healthcare-workers":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,48,80,109,135,169,191],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100578686","phase-1-psilocybin-assisted-therapy-for-physician-well-being-and-burnout-100578686",false,"NCT06814522","Psilocybin-Assisted Therapy for Physician Well-Being and Burnout","Psilocybin-Assisted Therapy for Physician Well-Being and Burnout: Feasibility, Safety, Clinical Effectiveness and Biomarkers of Response [PAT-B (Psilocybin-Assisted Therapy for Physician Well-Being and Burnout)]","PAT-B","Inclusion Criteria:\n\n1. UCSD faculty physician, aged 21-70. Volunteer faculty are not included\n2. Meets criteria for physician burnout\n3. Experiencing symptoms of burnout for \\>6 months\n4. Able to complete all required study visits\n5. Not previously diagnosed with a serious mental illness (including schizophrenia, bipolar disorder, and severe depression), or substance use disorder as confirmed in clinical interview\n6. Not currently taking any psychotropic medications or nonpsychotropic medication that may be associated with serotonin syndrome, such as serotonin reuptake inhibitors (SSRI or SNRI), dextromethorphan, linezolid, tramadol, meperidine\n\nExclusion Criteria:\n\n1. Previous inpatient psychiatric hospitalization(s)\n2. Previously diagnosed with a psychotic disorder (schizophrenia, schizoaffective disorder, or other psychotic spectrum disorder), bipolar spectrum disorder, personality disorder (borderline personality disorder, antisocial personality disorder, or other severe personality disorders), any severe psychiatric disorder.\n3. Exhibiting elevated suicide risk\n4. First degree family history of psychosis or bipolar disorder\n5. Prior exposure to psilocybin or other psychedelic compounds in the previous 10 years\n6. Currently pregnant, nursing, planning pregnancy, engaging in sexual intercourse without effective contraceptive method in last three months\n7. Those who plan to donate sperm within three months following the study.\n8. Known cardiovascular disease including history of stroke, myocardial infarction, uncontrolled hypertension, valvular heart disease, tachycardia, elongated QT interval, or clinically significant arrythmia.\n9. History of seizure disorder\n10. Use of recreational illicit drugs\n11. Clinically concerning results from vital signs, ECG, physical examination, or laboratory tests during screening\n12. Any other clinically significant illnesses deemed to pose risk for the participant","ALL","21 Years","70 Years",{"count":21,"type":22},10,"ESTIMATED","INTERVENTIONAL",[25,26],"PHASE1","PHASE2","Through an open-label study involving a small group of UCSD physicians experiencing burnout, the investigators will evaluate the feasibility, safety, and preliminary effectiveness of PAT to reduce burnout symptoms.",[29,30],"Burnout","Burnout, Healthcare Workers",[32,33,34],"burnout","physician","doctor","RECRUITING","2026-06-23",{"date":38,"type":39},"2026-06-26","ACTUAL",{"date":41,"type":39},"2025-01-13",{"date":43,"type":22},"2027-07",{"name":45,"class":46},"University of California, San Diego","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100644161","virtual-reality-for-enhancing-self-compassion-and-reducing-burnout-among-healthcare-providers-100644161","NCT07666867","Virtual Reality for Enhancing Self Compassion and Reducing Burnout Among Healthcare Providers","VR-CF-CBT","Inclusion Criteria:\n\n* have at least one year of experience working in a healthcare setting\n\nExclusion Criteria:\n\n* participating in other behavioral interventions that could confound study results\n* auditory or visual impairments that would interfere with VR usage\n* Participants who experience clinically significant VR-related discomfort\u002Fmotion sickness as assessed by the Simulator Sickness Questionnaire (SSQ)",true,{"count":57,"type":22},52,[59],"NA","Healthcare providers in high-demand clinical settings are at high risk for burnout and secondary traumatic stress due to repeated exposure to patient trauma, which can compromise well-being and quality of care. Compassion-focused cognitive behavioral therapy (CF-CBT) can reduce stress and enhance self-compassion, but traditional delivery is time- and resource-intensive. This project evaluates the feasibility, acceptability, and potential effectiveness of virtual reality (VR)-enhanced CF-CBT specifically adapted for healthcare providers experiencing vicarious trauma. Grounded in Neff's self-compassion framework (emphasizing self-kindness, common humanity, and mindfulness) the VR intervention provides 8 immersive environments where participants can practice compassion-focused skills, engage in procedural learning, and regulate emotional responses in real time.\n\nThe study will be conducted at UC San Diego Health using a two-arm randomized design comparing VR-enhanced CF-CBT with self-guided compassion-focused CBT\u002Fmindfulness exercises delivered without VR. Participants will complete 8 brief VR interventional sessions (approximately 6-10 minutes each) over 4-6 weeks. Outcomes include self-compassion, burnout, and secondary traumatic stress, measured using validated instruments. Feasibility and acceptability will be evaluated through recruitment, retention, session completion, engagement, and participant feedback.\n\nFindings will provide preliminary evidence for VR-enhanced compassion-focused interventions as a scalable and accessible approach to supporting healthcare providers' emotional well-being in demanding clinical environments, and will inform future cultural adaptation and implementation in low-resource and conflict-affected healthcare settings such as those in post-war zones.",[30,29,62,63,64],"Burnout, Psychological","Self Compassion","Empathy Training of Healthcare Professional Students",[66,67,68,69,70],"Self-Compassion","Empathy","CBT","Virtual Reality","Healthcare Provider Burnout","NOT_YET_RECRUITING","2026-06-18",{"date":74,"type":39},"2026-06-24",{"date":76,"type":22},"2026-07-01",{"date":78,"type":22},"2027-02-01",{"name":45,"class":46},{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":55,"sex":17,"minAge":88,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":23,"phases":91,"briefSummary":92,"conditions":93,"keywords":96,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":108},"100641701","projecte-benestar-2026-virtual-reality-program-for-healthcare-workers-100641701","NCT07649733","Projecte Benestar 2026: Virtual Reality Program for Healthcare Workers","Projecte Benestar 2026: Multicenter Study of the Effectiveness and Implementability of an Immersive Educational Program for Workers in Healthcare Settings","BENESTAR","Inclusion Criteria:\n\n* Active permanent or temporary staff member at a participating healthcare center where the program is implemented\n* Age 18 years or older\n* Able to understand, accept, and sign the informed consent form\n* Willing to complete the study procedures, attend the planned weekly sessions, and complete the study questionnaires\n\nExclusion Criteria:\n\n* Photosensitive epilepsy or history of seizures triggered by visual stimuli\n* Severe motion sickness or previous intolerance to immersive devices\n* Visual or hearing impairment that prevents adequate use of the virtual reality headset","18 Years",{"count":90,"type":22},100,[59],"Projecte Benestar 2026 is a multicenter randomized controlled study evaluating a brief immersive educational program delivered through virtual reality for healthcare workers. The program is designed to support emotional well-being, self-care, mindfulness, and emotional regulation in professionals working in healthcare settings.\n\nParticipants will be active healthcare or healthcare-support workers from participating centers. They will be randomly assigned to one of two groups. One group will receive the virtual reality program at the beginning of the study, while the other group will continue usual activity and receive the same program later, after a wait-list period.\n\nThe main objective is to evaluate whether the program reduces emotional exhaustion, measured with the Maslach Burnout Inventory. Secondary objectives include evaluating changes in depersonalization, personal accomplishment, work engagement, usability, satisfaction, adherence, and tolerability of the virtual reality program.",[30,94,95],"Occupational Stress","Mental Health Issue",[69,97,98,29],"Mindfulness","Healthcare workers","2026-06-10",{"date":101,"type":39},"2026-06-16",{"date":103,"type":39},"2026-06-08",{"date":105,"type":22},"2027-12",{"name":107,"class":46},"Badalona Serveis Assistencials",2,{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":4,"eligibilityCriteria":115,"healthyVolunteers":55,"sex":17,"minAge":88,"maxAge":116,"enrollmentInfo":117,"targetDuration":4,"studyType":23,"phases":119,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":134},"100609736","a-study-of-resilience-and-mental-well-being-through-breathing-practice-for-clinical-care-professionals-100609736","NCT07218458","A Study Of Resilience And Mental Well-Being Through Breathing Practice For Clinical Care Professionals","Enhancing Resilience And Mental Well-Being Through Breathing Practice For Clinical Care Professionals (Breathing Study-Burnout)","Inclusion Criteria:\n\n* Participants must be healthcare professionals at the above-mentioned 4 MCHS sites (Eau Claire, La Crosse, Mankato, Albert Lea).\n* Must score ≥40 on Copenhagen Burnout Inventory Q1-6.\n* Participants must be physically fit enough to perform light exercise.\n* Participants should read and understand English well enough to consent, complete measures, and follow instructions.\n* Participants must have access to a smartphone or tablet.\n\nExclusion Criteria:\n\n* Active primary psychotic disorder or substance use disorder (except nicotine dependence) within the past year.\n* Severe or unstable medical condition that could interfere with participation or data collection.\n* Active neurological condition (including seizure disorder, traumatic brain injury, or stroke) that could affect cognitive functioning or brain imaging results.\n* Chronic lung disease (e.g., COPD, cystic fibrosis) or aneurysm.\n* Current pregnancy or planning to become pregnant during the study period","85 Years",{"count":118,"type":22},40,[59],"The purpose of this study is to assess the immediate and long-term effects of structured breathing on clinical symptoms related to mental health including anxiety, depression, perceived stress, and sleep quality.",[30,122],"Breathing Exercises",[32,124],"breathing","2026-04-29",{"date":127,"type":39},"2026-05-05",{"date":129,"type":39},"2025-10-27",{"date":131,"type":22},"2026-11-30",{"name":133,"class":46},"Mayo Clinic",4,{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":17,"minAge":88,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":23,"phases":145,"briefSummary":146,"conditions":147,"keywords":152,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":168},"100623441","operating-room-black-box-supported-debriefings-and-their-effect-on-healthcare-professionals-effectiveness-and-psychological-safety-100623441","NCT07396675","Operating Room Black Box Supported Debriefings and Their Effect on Healthcare Professionals Effectiveness and Psychological Safety.","Improving Postoperative Debriefings: the Added Value of Operating Room Black Box Supported Debriefings and Their Effect on Healthcare Professionals Perceived Effectiveness and Psychological Safety.","ORBLACKBOX","Inclusion Criteria:\n\n* Participants work in an OR-team at RIGS, AUMC or UKE.\n* Participants must have given informed written consent to participate in the study.\n* Participants must be in the OR for the majority of the procedure or\u002Fand have a central role in the teamwork.\n* At RIGS and AUMC participants for the ORBB debriefings must also be part of teams conducting surgeries in the OR where ORBB is installed (not all ORs have ORBB).\n* Participants can either be surgeons, anesthesiologist, anesthesia nurses, residents, OR-nurses, perfusionists, interns, nurse students or other OR-staff.\n\nExclusion Criteria:\n\n* Visitors, guests, and other staff only watching the surgery, are excluded from participation.\n* Individuals who are unable or unwilling to provide written informed consent.",{"count":144,"type":22},135,[59],"This study is enrolled in the European KEEPCARING Project. KEEPCARING aims to (re-)build wellbeing and resilience of healthcare workforce in EU hospitals by co-creating a multi-faceted non-digital, digital, and AI-supported solution package to prevent burnout among (aspirant) healthcare professionals on the individual, team, and organizational level.\n\nThis study specifically investigate the operating room staff wellbeing and resilience. The healthcare system is currently struggling to retain and attract operating room personnel. A factor of importance to consider here is occupational stress. If not recognized or mitigated well, occupational stress and personal efficacy can eventually evolve into a syndrome labelled as 'burnout'. In addition, communication and resilience patterns between operating room staff members are of influence, poor and\u002For inadequate communication among staff may be a factor of stress, compromising their work and wellbeing. In contrast, communication patterns that have a high standard and clarity may support resilience. The ability to speak up and being able to advocate concerns of all team members is of the highest importance here. Indeed, psychological safety and effective teamwork patterns are key for the working environment, performance, patient safety, and job satisfaction. To prevent mistakes during surgery, a safe space where team members can freely speak up is vital.\n\nTo improve psychological safety, and teamwork among OR staff, team debriefing after surgery is known to be effective. What is not known; is whether team debriefing with the additional support derived from audio- and video recordings of the surgery is equally effective as debriefing without.\n\nThe objective of this study is to evaluate the impact of structured postoperative debriefings with and without procedural, structured audio- and video recordings, on team performance, psychological safety, and non-technical skills in the operating room. Specifically, this study aims to compare augmented debriefings with non-augmented debriefings, to assess differences in perceived usefulness, psychological safety, and observed improvements in teams' non-technical skills.\n\nThis is an international quasi-experimental comparative study. The intervention consists of postoperative team debriefing using audio and video recordings ('augmented debriefing') from Operating Room Black Box system provided by Surgical Safety Technologies. The control group will have a postoperative team debriefing that is not augmented with Operating Room Black Box derived data. An identical debriefing template will be designed for both groups.",[148,149,150,30,151],"Stress","Resilience","Psychological Safety","Teamwork",[153,154,155,156,157],"debriefing","teamwork","psychological safety","operating room","operating room black box","2026-04-15",{"date":160,"type":39},"2026-04-20",{"date":162,"type":39},"2026-03-01",{"date":164,"type":22},"2027-10-01",{"name":166,"class":167},"ORNND - Operating Room Nurse Network Denmark","NETWORK",3,{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":55,"sex":17,"minAge":88,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":23,"phases":179,"briefSummary":180,"conditions":181,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":4},"100591312","generative-artificial-intelligence-nurse-staffing-study-100591312","NCT06978790","Generative Artificial Intelligence Nurse Staffing Study","Generative Artificial Intelligence Nurse Staffing (GAINS) Study","GAINS","Inclusion Criteria:\n\n* Registered nurses, nursing assistants, or key stakeholders\n* Employed by The Queen's Medical Center\n* Working at least 24 hours per week\n* Position associated with medical-surgical units where float pool nurses work\n\nExclusion Criteria:\n\n* Employees working less than 24 hours per week at The Queen's Medical Center\n* Employees whose roles are not related to medical-surgical units",{"count":178,"type":22},660,[59],"This study is guided by Maslach's Burnout Theory and with Normalization Process Theory supporting the implementation of the GAINS intervention by facilitating its integration into routine system-level practice. In Year 1, the investigative team will collaborate with hospital-based nursing leadership and key stakeholders to identify staffing-specific factors essential for operationalizing the GAINS AI model\u002Fintervention. In Year 1, the investigators will also conduct a survey amongst nursing staff to measure baseline burnout. In Year 2, the AI-staffing intervention will be implemented with the medical-surgical nursing float pool team. In Year 3, the investigators will first repeat the nurse burnout survey and second, expand the intervention to include the nursing assistant float pool team. In Year 4, the investigators will conduct the final burnout survey with nurses, assess feasibility of GAINS (target vs. actual staffing- nurses and nursing assistants), and assess preliminary efficacy of GAINS to reduce costs related to staffing. the investigators will compare outcomes at three time points (pre, mid, and post-intervention). Interviews with nurses, nursing assistants, unit nurse managers, and leadership will further explicate the intervention's acceptability, feasibility, and impact on burnout.",[30],"2025-05-15",{"date":184,"type":39},"2025-05-18",{"date":186,"type":22},"2026-04-01",{"date":188,"type":22},"2029-03-31",{"name":190,"class":46},"University of Hawaii",{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":17,"minAge":88,"maxAge":4,"enrollmentInfo":199,"targetDuration":201,"studyType":202,"phases":4,"briefSummary":203,"conditions":204,"keywords":216,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":225,"startDateStruct":227,"completionDateStruct":229,"leadSponsor":231,"locationsCount":4},"100587057","survey-of-psychological-well-being-of-health-care-workers-in-the-hospital-setting-100587057","NCT06923436","Survey of Psychological Well-being of Health Care Workers in the Hospital Setting","FROM THE INVISIBLE TO THE VISIBLE: Survey on the Psychological Well-being of Hospital Healthcare Workers","IN-VISIBLE","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Work activity carried out in departments classified as at risk for work-related stress (emergency care, oncology...)\n* Willingness to participate in the study and the ability to understand and sign the informed consent form.\n\nExclusion Criteria:\n\n* Psychological\u002Fpsychiatric comorbidities\n* Inability to sign the informed consent form",{"count":200,"type":22},500,"4 Months","OBSERVATIONAL","The psychological well-being of healthcare workers in hospital settings is a topic of growing interest in the scientific literature, given the crucial importance of their role in ensuring high-quality care. In addition, the Covid-19 pandemic health emergency has further accentuated the relevance of this issue, increasing anxiety and stress levels, testing the resilience and resistance of those working in care settings, revealing and highlighting how the accumulation of work-related stress can result in disabling pathologies for the caregiver, with an inevitable impact on the facility and care in general. Recent studies show that health care workers are particularly vulnerable to work-related stress, which can result from various factors such as high work demands, emotional pressure, irregular shifts, and interactions with critically ill patients. Burnout syndrome, characterized by emotional exhaustion, depersonalization and reduced personal accomplishment, is widely documented among hospital staff. Research indicates that burnout not only compromises the psychological health of healthcare workers, but also negatively affects the quality of care provided by increasing the risk of medical errors.\n\nIn light of these factors, it is crucial to deepen our understanding of the dynamics that influence psychological well-being and work-related stress in health care workers in order to develop effective interventions that can improve their quality of life and consequently the quality of care provided to patients.\n\nPreliminary assessment of the emotional burden and motivational aspects of health care workers (showing what very often eludes a first glance, making visible something that is often invisible), along with effective stress management, would allow for greater ability to remain calm under pressure, reduced frustration, increased ability to make informed decisions, and to communicate effectively with patients and colleagues. These aspects translate into an image of a safer and more caring health care system in promoting better quality of care.\n\nThe aim of this project is to highlight the importance of psychological wellbeing for those working in health care settings and to promote attention to this area, also with a view to identifying possible interventions aimed at identifying preventive and protective factors in relation to health care workers.\n\nThe aim, therefore, is to show what is very often invisible at first sight, to make visible what is invisible: to explore, accommodate and contain areas of criticality and fragility in the context of work in health care settings, working on interventions aimed at the psychological well-being of workers.",[205,206,207,208,149,209,210,211,212,30,213,214,215],"Healthy","Psychological Well Being","Stress Response","Professional Quality of Life","Alexithymia","Spirituality","Coping Skills","Job-related Affective Well-being","Empathy Skills","Quality of Life Outcomes","Technostress",[217,218,219,220,221,222,223],"Psychological well-being of health care workers in the hospital setting","work-related stress","emotional burden","Motivational aspects of health professionals","occupational well-being","Perceived Stress","Perceived stress from the intensive use of digital technology in work settings","2025-04-23",{"date":226,"type":39},"2025-04-27",{"date":228,"type":22},"2025-04",{"date":230,"type":22},"2026-04",{"name":232,"class":46},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS"]