[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"burnout-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:burnout-syndrome":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,50,108,135,177,206,233,260],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100053787","prevention-of-burnout-in-spanish-healthcare-professionals-through-attachment-based-compassion-therapy-abct-100053787",false,"NCT07698379","Prevention of Burnout in Spanish Healthcare Professionals Through Attachment-Based Compassion Therapy (ABCT)","Mindfulness-based and Compassion-based Interventions in Anxious-Depressive Symptomatology in Mental Health Services: A Randomized Controlled Trial.","Inclusion Criteria:\n\n1. Active healthcare professionals (physicians and nurses) of both sexes.\n2. Understanding of spoken and written Spanish.\n3. Availability of a computer and internet connection.\n4. Written informed consent.\n\nExclusion Criteria:\n\n* Previous psychological treatment within the last year, or current psychological treatment.\n\nPresence of a severe uncontrolled medical, infectious, or degenerative disease that may interfere with affective symptoms.\n\nPresence of a mental disorder related to substance dependence\u002Fabuse, or any other disease affecting the central nervous system.\n\nSuicide risk, defined as a score of ≥2 on item 9 of the PHQ-9. Scheduled surgical intervention during the course of the study.","ALL","18 Years","75 Years",{"count":20,"type":21},180,"ESTIMATED","INTERVENTIONAL",[24],"NA","Burnout is a common problem among healthcare professionals and may affect their psychological well-being, quality of life, and professional functioning. This study will examine whether an intensive compassion-based intervention can help reduce burnout and improve well-being in healthcare professionals. Participants will be randomly assigned to either an Attachment-Based Compassion Therapy intervention or a relaxation intervention. Outcomes will be measured before the intervention, immediately after the intervention, and three months later.\n\nAttachment-Based Compassion groups will be composed of 80 participants each, and TAU group will be composed of 80 participants (total sample n = 160).\n\nBurnout Inventory-Human Services Survey - MBI-HSS. Burnout will be assessed using the Maslach Burnout Inventory-Human Services Survey. This questionnaire evaluates the three main dimensions of burnout: emotional exhaustion, depersonalization, and personal accomplishment.\n\nItems are rated on a Likert-type scale according to the frequency with which the participant experiences each symptom. Scores are calculated separately for each burnout dimension.\n\nIn this study, emotional exhaustion and depersonalization will be considered the primary outcome variables, while reduced personal accomplishment will be considered a secondary outcome variable",[27,28,29],"Burnout Syndrome","Anxiety Depression","Stress",[31,32,33,34,35,36],"burnout","anxiety","Mindfulness","Compassion","ABCT","healthcare personnel","RECRUITING","2026-07-07",{"date":40,"type":41},"2026-07-13","ACTUAL",{"date":43,"type":21},"2026-07-10",{"date":45,"type":21},"2028-04-30",{"name":47,"class":48},"Hospital Miguel Servet","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":59,"targetDuration":61,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":77,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":49},"100640521","neurofinance-human-stress-trial-during-financial-and-informational-volatility-100640521","NCT07622589","NeuroFinance Human Stress Trial During Financial and Informational Volatility","NeuroFinance Human Stress Trial During Financial and Informational Volatility (NFHST)","NFHST","Inclusion Criteria:\n\n* Adults age 18 years and older.\n* Ability to provide informed consent.\n* Willingness and ability to comply with study procedures and remote monitoring requirements.\n* Access to a compatible smartphone, tablet, or internet-connected device for decentralized study participation.\n* Willingness to utilize wearable physiologic monitoring technologies during the study period.\n* Participants with varying degrees of financial market exposure, occupational stress exposure, or digital media exposure are eligible.\n* Healthy volunteers and participants with self-reported stress-related symptoms may be enrolled.\n* Ability to read and understand English-language consent and study materials.\n\nExclusion Criteria:\n\n* Individuals unable or unwilling to provide informed consent.\n* Individuals unable to comply with remote monitoring procedures or wearable device usage requirements.\n* Active medical or psychiatric instability that, in the opinion of study investigators, may interfere with study participation or data integrity.\n* Current incarceration or institutionalization limiting voluntary participation.\n* Participation in another interventional clinical trial that may substantially interfere with physiologic monitoring outcomes.\n* Any condition that would significantly impair safe study participation as determined by the study investigators.",true,{"count":60,"type":21},2500,"24 Months","OBSERVATIONAL","The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven stress environments affect human physiologic and behavioral health. Participants will undergo remote monitoring using wearable biosensors, cardiovascular telemetry devices, sleep tracking systems, heart rate variability monitoring, and behavioral analytics platforms. The study will use artificial intelligence and machine learning systems to analyze relationships between external financial and informational events and biologic stress responses, including autonomic nervous system activity, sleep disruption, cardiovascular strain, emotional resilience, and inflammatory signaling. The goal of the study is to develop predictive digital biomarkers and AI-assisted forecasting systems capable of identifying stress-related physiologic deterioration before clinical manifestation.",[65,66,67,68,69,70,71,72,73,74,27,75,76],"Psychological Stress","Anxiety","Emotional Stress","Autonomic Nervous System Dysfunction","Sleep Disturbance","Insomnia","Behavioral Health","Cognitive Fatigue","Occupational Stress","Financial Stress","Heart Rate Variability","Neurobehavioral Manifestations",[78,79,80,81,82,83,75,84,85,86,87,88,89,90,91,92,93,94,95,96],"NeuroFinance","Financial Stress Medicine","Wearable Biosensors","Artificial Intelligence","Machine Learning","Digital Biomarkers","Sleep Monitoring","Behavioral Analytics","Cardiovascular Telemetry","Decentralized Clinical Trial","Emotional Resilience","Physiologic Stress","Market Volatility","Economic Uncertainty","Social Media Exposure","Cognitive Performance","Stress Forecasting","Precision Wellness","Remote Patient Monitoring","NOT_YET_RECRUITING","2026-05-27",{"date":100,"type":41},"2026-06-03",{"date":102,"type":21},"2026-07-15",{"date":104,"type":21},"2029-06-30",{"name":106,"class":107},"Truway Health, Inc.","INDUSTRY",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":58,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":116,"targetDuration":4,"studyType":22,"phases":118,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":4},"100628302","self-care-program-and-burnout-prevention-in-first-year-medical-oncology-residents-mixed-methods-quasi-experimental-study-100628302","NCT07459868","Self-Care Program and Burnout Prevention in First-Year Medical Oncology Residents (Mixed-Methods Quasi-Experimental Study)","A Prospective Mixed-Methods Quasi-Experimental Study Evaluating Burnout Variation Over 12 Months and the Influence of a Self-Care and Burnout Prevention Program in First-Year Medical Oncology Residents","CARE-ONC","Inclusion Criteria:\n\n* First-year medical oncology residents at FALP; continued residency enrollment; minimum attendance requirement per protocol (≥75%).\n\nExclusion Criteria:\n\n* Maternity leave during the study period.\n* Interruption\u002Fwithdrawal from the residency program.",{"count":117,"type":21},9,[24],"Burnout is highly prevalent among oncology clinicians, including residents in training. This prospective, mixed-methods, quasi-experimental study will evaluate how burnout changes over 12 months during the first year of medical oncology residency and explore which work-related, professional identity, and program support factors influence this variation.\n\nResidents will participate in a structured self-care and burnout prevention program with multiple modules (e.g., yoga, mindfulness, art therapy, music therapy, Balint groups, workshops, mentorship). Quantitative burnout outcomes will be measured using the Maslach Burnout Inventory (MBI-HSS), and qualitative insights will be collected through individual semi-structured interviews. The study will also describe sociodemographic characteristics, baseline burnout prevalence, participation\u002Fadherence, satisfaction, and implementation barriers\u002Ffacilitators.",[27,121],"Professional Burnout",[123,124,125],"medical oncology residents","burnout syndrome","self care program","2026-03-10",{"date":128,"type":41},"2026-03-11",{"date":130,"type":21},"2026-03-02",{"date":132,"type":21},"2027-05-31",{"name":134,"class":48},"Fundacion Arturo Lopez Perez",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":146,"conditions":147,"keywords":150,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":168,"lastUpdatePostDateStruct":169,"startDateStruct":171,"completionDateStruct":173,"leadSponsor":175,"locationsCount":49},"100612571","strengthening-health-literacy-in-healthcare-workers-through-mind-body-medicine-and-nutrition-100612571","NCT07255313","Strengthening Health Literacy in Healthcare Workers Through Mind Body Medicine and Nutrition","Strengthening Psycho-physiological and Psycho-emotional Competencies in Healthcare Workers Through Mind Body Medicine and Nutrition: A Randomized Controlled Trial","SOULFOOD","Inclusion Criteria:\n\n* Age 18 years and older\n* Employees of University Medicine Essen\n* Moderate resilience of ≤ 144 points on the RS-25\n* Willingness to practice at home and keep a practice diary\n\nExclusion Criteria:\n\n* Insufficient German language skills\n* Pregnancy and breastfeeding\n* Severe comorbid mental disorders (e.g., substance use disorder, major depression) or other severe comorbid somatic diseases (e.g., oncological disease without remission, severe pre-existing cardiovascular disease, organ failure, other severe neurological disorders)\n* Planned or ongoing pension application (e.g., disability pension, occupational disability, reduced earning capacity, severe disability)\n* Concurrent participation in other clinical intervention studies",{"count":144,"type":21},252,[24],"This is a randomized controlled trial aiming to develop and evaluate a workplace health program to improve stress resilience and mental well-being among healthcare workers at University Medicine Essen using a participatory research design (including a steering committee composed of hospital staff, needs assessment through focus groups, and pilot testing). The intervention combines mind-body medicine techniques, complementary medicine self-care strategies, and psycho-biotic nutrition. If successful, the program will be integrated into routine workplace health management and serve as a model for other healthcare institutions.",[148,29,149,27],"Stress Resilience","Burnout",[151,152,153,154,155,156,157,158,159,160,161,162,163,164,165,166,167],"stress resilience","work health promotion","burnout prevention","mental well-being","occupational stress","healthcare workers","Mind-Body Medicine","complementary medicine","nutrition","employee health","participatory research","randomized controlled trial","workplace intervention","self-care strategies","occupational health management","Self-Efficacy and Stress Resistance","nutrition and mental health","2025-12-07",{"date":170,"type":41},"2025-12-15",{"date":172,"type":41},"2025-12-01",{"date":174,"type":21},"2027-08-31",{"name":176,"class":48},"Universität Duisburg-Essen",{"id":178,"slug":179,"hasResults":11,"nctId":180,"briefTitle":181,"officialTitle":182,"acronym":4,"eligibilityCriteria":183,"healthyVolunteers":58,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":184,"targetDuration":4,"studyType":22,"phases":186,"briefSummary":187,"conditions":188,"keywords":189,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":205},"100595345","evidence-based-quality-improvement-to-reduce-va-primary-care-burnout-100595345","NCT07031245","Evidence-Based Quality Improvement to Reduce VA Primary Care Burnout","Reducing Burnout Among VA PCPs Using Evidence-Based Quality Improvement","Site Inclusion Criteria:\n\n* 5 primary care clinics (2 VA Medical Centers \\[VAMCs\\] and 3 community-based outpatient clinics \\[CBOCs\\]) in 2 VA healthcare systems in 1 VA Veterans Integrated Service Network\n\nProvider and Staff Inclusion Criteria:\n\n* Primary care providers, registered nurses, clinical associates (e.g., licensed vocational or practical nurses), or administrative associates (e.g., clerks) on regular Patient-Aligned Care Team (PACT) teamlets at a study site.\n\nSite Exclusion Criteria:\n\n* All other VAMCs and CBOCs.\n\nProvider and Staff Exclusion Criteria:\n\n* Other primary care professionals at a study site.\n* Members of special types of PACT teamlets at a study site.",{"count":185,"type":21},203,[24],"Burnout is highly prevalent among VA primary care providers and staff, impairing productivity and retention, as well as safety, quality, and patient experience. In this pilot trial, the investigators will facilitate the development of burnout reduction interventions using an evidence-based quality improvement (EBQI) approach, and then evaluate the feasibility, acceptability and effectiveness of a pilot EBQI-facilitated burnout reduction intervention in a modified stepped wedge design in one VA region.",[149,27],[190,191,31,192,193,194],"primary care","VA","EBQI","evidence-based","quality improvement","2025-09-17",{"date":197,"type":41},"2025-09-23",{"date":199,"type":21},"2025-10-01",{"date":201,"type":21},"2028-09-30",{"name":203,"class":204},"VA Greater Los Angeles Healthcare System","FED",5,{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":211,"acronym":212,"eligibilityCriteria":213,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":214,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":216,"conditions":217,"keywords":218,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":225,"startDateStruct":227,"completionDateStruct":229,"leadSponsor":231,"locationsCount":49},"100598247","burnout-syndrome-in-the-intensive-care-unit-before-and-during-a-palliative-care-trial-100598247","NCT07069010","Burnout Syndrome in the Intensive Care Unit Before and During a Palliative Care Trial","Evaluation of Burnout Syndrome Among Healthcare Professionals in Intensive Care Units Within the EPIC (Enhancing Palliative Care in ICU) Research","BURNOUT-EPIC","Inclusion Criteria:\n\n* ICU clinicians (nurses, physicians, advanced practice providers) actively caring for critically ill patients\n* Employed in participating ICUs for ≥3 months prior to study start\n* Willing to complete both pre- and during-intervention surveys\n* Consent to participate in educational tele-palliative care trial\n\nExclusion Criteria:\n\n* Locum tenens or temporary staff not continuously assigned to the unit\n* Clinicians on leave (medical, parental, or extended leave) during either survey period\n* Prior enrollment in similar palliative care training within past 6 months",{"count":215,"type":21},100,"One hundred ICU doctors, nurses and psychologists from the 28 units participating in the EPIC stepped-wedge trial (ClinicalTrials.gov NCT06605079) will each complete the same four-part survey twice-once during their unit's usual-care phase and again during the EPIC tele-palliative-care intervention. The questionnaire begins with Part A, gathering demographic and professional details such as age, gender, family status, education, role, years of ICU service, shift patterns, leave days and any prior palliative-care or ethics training. Part B then probes 22 workplace stressors and ethical dilemmas-resource constraints, family pressures, moral conflicts, emotional distancing from colleagues, perceived control over decisions and work-life balance-using a five-point frequency scale. Part C merges a 19-item Maslach Burnout Inventory subset (emotional exhaustion, depersonalization, personal accomplishment) on a seven-point frequency scale with a 16-item Oldenburg Burnout Inventory subset (exhaustion, disengagement) on a four-point agreement scale. Finally, Part D employs Neff's 16-item Self-Compassion Scale-rated from almost never to almost always-to assess self-kindness, common humanity, mindfulness, self-judgment, isolation and over-identification. Within-subject, repeated-measures analyses of total and subscale scores will quantify how EPIC's blended-learning curriculum and standardized teleconsultations shift clinician burnout profiles and self-compassion over time.",[27],[219,220,221,222,223],"ICU burnout","Moral distress","self compassion","Tele-palliative care","repeated measures survey","2025-07-29",{"date":226,"type":41},"2025-08-01",{"date":228,"type":41},"2025-07-15",{"date":230,"type":21},"2027-09-30",{"name":232,"class":48},"University of Athens",{"id":234,"slug":235,"hasResults":11,"nctId":236,"briefTitle":237,"officialTitle":237,"acronym":238,"eligibilityCriteria":239,"healthyVolunteers":58,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":240,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":242,"conditions":243,"keywords":244,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":251,"lastUpdatePostDateStruct":252,"startDateStruct":254,"completionDateStruct":256,"leadSponsor":258,"locationsCount":49},"100571519","continuous-heart-rate-variability-monitoring-in-doctors-understanding-patterns-of-stress-and-recovery-and-their-relationship-with-self-reported-resilience-burnout-and-wellbeing-100571519","NCT06721312","Continuous Heart Rate Variability Monitoring in Doctors; Understanding Patterns of Stress and Recovery and Their Relationship With Self-reported Resilience, Burnout and Wellbeing.","HEART-ED","Inclusion Criteria:\n\n* Working within NHS Grampian\n* Access to a smartphone\n\nExclusion Criteria:\n\n* Cardiac arrhythmias\u002Fendocrine disease.\n* Prescription beta blockers, calcium channel blockers, ACE inhibitors, benzodiazepines, antidepressants and antianxiety medications.\n* Insufficient non-working time prior to study commencement.",{"count":241,"type":21},60,"Burnout is an increasing concern in the medical professions. This study aims to utilise established, validated self-report measures combined with continuous heart rate variability measurements to better understand the stress and recovery patterns experienced by doctors that may contribute to burnout.\n\nThis mixed methods study design will consist of an ecological momentary assessment phase where participants will complete commonly used and validated real-time subjective measures while concurrently wearing a heart rate variability monitor to provide an objective measure of stress. Following on from this, participants of interest will be invited to participate in semi structured interviews to further explore their experiences of stress and recovery.",[149,27,73,29],[245,246,155,247,248,249,250,31],"Heart rate variability","HRV","resilience","fatigue","wellbeing","stress","2024-12-06",{"date":253,"type":41},"2024-12-11",{"date":255,"type":21},"2024-12-09",{"date":257,"type":21},"2025-10-31",{"name":259,"class":48},"University of Aberdeen",{"id":261,"slug":262,"hasResults":11,"nctId":263,"briefTitle":264,"officialTitle":265,"acronym":4,"eligibilityCriteria":266,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":267,"enrollmentInfo":268,"targetDuration":4,"studyType":22,"phases":270,"briefSummary":272,"conditions":273,"keywords":274,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":279,"lastUpdatePostDateStruct":280,"startDateStruct":282,"completionDateStruct":284,"leadSponsor":286,"locationsCount":49},"100563521","early-phase-1-effects-of-cannabidiol-on-burnout-syndrome-and-empathy-of-caregivers-of-older-adults-100563521","NCT06617247","Effects of Cannabidiol on Burnout Syndrome and Empathy of Caregivers of Older Adults","Effects of Cannabidiol on Burnout Syndrome and Empathy of Paid and Unpaid Caregivers of Older Adults","Inclusion Criteria:\n\n* Total score 4 in the IEAVD\n* Score on the emotional exhaustion subscale of MBI 9 and\u002For depersonalization 6 and\u002For; professional achievement 10\n* Low level of empathy in the EMRI scale (i.e., total score 71)\n* In addition, they should have a score of 10 on the PHQ-9, indicating absence of expressive depressive symptoms\n\nExclusion Criteria:\n\n* Not have the availability to participate in this phase of the research will be excluded\n* Who have ceased to exercise the position of carer of a person aged 60 years or more\n* Who no longer perform minimum workload of six hours daily and\n* Not complete the protocol of the intervention received.","50 Years",{"count":269,"type":21},26,[271],"EARLY_PHASE1","Burnout syndrome is an occupational disease that has affected health care providers, for example, caregivers of older adults. This syndrome negatively affects physical and psychological health, which may reflect on the mental health of the caregiver and the care provided to the older adults. Interventions have been developed to minimize the impacts of burnout. Thus, this study has two main objectives: 1) to identify the effect of cannabidiol on indicators of burnout and empathy of caregivers of older people with functional dependence for activities of daily living; 2) identify possible associations between burnout indicators, empathy levels and their domains, and quality of care. This is a two-phase study (i.e., Phase 1: cross-sectional; Phase 2: clinical trial). In Phase 1, caregivers will answer questionnaires developed by researchers for sociodemographic characterization, care and satisfaction of care. In addition, they will complete instruments to assess the functional dependence of the older people - EIAVD, depressive symptoms - PHQ-9, social support - EAS, Burnout syndrome - MBI and Empathy - EMRI and MET. In Phase 2, caregivers will be randomized to cannabidiol or placebo intervention. Caregivers with number 0 will be allocated to the intervention using cannabidiol (300mg - divided into two times a day) and those drawn with number 1 will be allocated to the placebo group. Both interventions will be performed for four weeks. Caregivers will fill in the MBI, EMRI, MET, NPI and QAO instruments before and after the intervention. UKU-SERS will also be applied to evaluate side effects, IECC to assess the impact of intervention on care and CGI to assess severity and response to treatment.",[27],[275,276,277,278],"cannabidiol","caregivers","empathy","Burnout syndrome","2024-09-26",{"date":281,"type":41},"2024-10-01",{"date":283,"type":21},"2024-12-01",{"date":285,"type":21},"2026-12-31",{"name":287,"class":48},"University of Sao Paulo"]