[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bypass-cardiopulmonary\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bypass-cardiopulmonary":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100632029","menthol-massage-for-post-bypass-pain--anxiety-100632029",false,"NCT07508371","Menthol Massage for Post-Bypass Pain & Anxiety","The Effect of Back Massage With Mentholated Ointment After Coronary Artery Bypass Graft Surgery on Pain and Anxiety Levels","Menthol Care","Inclusion Criteria:\n\n* Willing to participate in the study,\n* Who has undergone bypass surgery,\n* Aged 18 years or older,\n* No visual impairment (except those who can see better with visual aids), hearing impairment (except those who can hear better with hearing aids), or speech impairment\u002Fcommunication problems that would prevent them from understanding the information provided and accurately describing their pain,\n* Literate,\n* Possesses orientation to person, place, and time,\n* Has a sternum exposure time of at least 2 hours during surgery,\n* Does not use any complementary alternative medicine methods,\n* Meets ASA 1 and ASA 2 criteria,\n* Elective (planned) surgery patients will be included.\n\nExclusion Criteria:\n\n* Individuals with allergies to menthol ointment and paraffin oil used during the procedure,\n* Individuals participating in a different study conducted at the clinic,\n* Individuals experiencing confusion,\n* Individuals with physical and cognitive problems that prevent massage from being applied,\n* Individuals diagnosed with mood disorders (depression, panic attacks, dysthymia, bipolar disorder, or taking any medication for these conditions),\n* Individuals with respiratory problems,\n* Individuals who cannot speak Turkish, and cannot read or write Turkish\n* Transferred to intensive care during the postoperative period,\n* Experiencing severe bleeding, hematoma, seroma, or nerve injury during the postoperative period,\n* Developing an allergy to mentholated ointment\u002Fparaffin oil used during massage,\n* Voluntarily requesting to leave the job,\n* Individuals who do not comply with the work process and conditions will be removed from the study.","ALL",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","This randomized controlled trial aims to evaluate the effectiveness of mentholated ointment massage in reducing pain and anxiety levels in patients who have undergone coronary bypass surgery, volunteered to participate in the study, and met the inclusion criteria.\n\nGroup 1: Back massage with mentholated ointment (Vicks) Group 2: Back massage with paraffin oil Group 3 (Control): Routine clinical treatment The comparison group consists of the group receiving a back massage with paraffin oil and the control group (routine clinical treatment).\n\nThe questions it aims to answer are:\n\nH1: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces back pain levels compared to patients receiving routine treatment.\n\nH2: Back massage with paraffin oil after coronary artery bypass graft surgery reduces back pain levels compared to patients receiving routine treatment.\n\nH3: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces anxiety levels compared to patients receiving routine treatment.\n\nH4: Back massage with paraffin oil after coronary artery bypass graft surgery reduces anxiety levels compared to patients receiving routine treatment.\n\nH5: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces back pain levels compared to back massage with paraffin oil.\n\nH6: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces anxiety levels compared to back massage with paraffin oil.\n\nPain intensity and vital signs will be monitored in all participants before surgery, at 0 minutes (before analgesia administration), and at 30 minutes after surgery. Additionally, vital signs will be observed before the back massage at 0 minutes and after at 15 minutes. Anxiety levels will be measured before surgery and 15 minutes after the back massage application. A total of 5 back massage applications will be performed until the patients are discharged.",[26],"Bypass, Cardiopulmonary",[28,29,30,31],"massage","menthol","anxiety","pain","NOT_YET_RECRUITING","2026-03-30",{"date":35,"type":36},"2026-04-02","ACTUAL",{"date":38,"type":20},"2026-09-25",{"date":40,"type":20},"2027-01-30",{"name":42,"class":43},"Istanbul Medipol University Hospital","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":64,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":44},"100620203","prognosis-of-patients-with-mixed-cardiogenic-vasoplegic-shock-100620203","NCT07354568","Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock","Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock: a French Multicenter Cohort","PROMIX","Inclusion Criteria:\n\n* Adult patient (\\>18 years old)\n* Admitted to an intensive care unit for cardiogenic shock, at least SCAI stage C\n* No opposition to data use\n\nExclusion Criteria:\n\n* Missing key data, particularly regarding vasopressor doses and outcomes.\n* Pregnant women\n* Non-eligible shock etiologies, including but not limited to:\n* Anaphylactic shock,\n* Isolated hemorrhagic shock,\n* Severe burns or major trauma,\n* Severe acute pancreatitis,\n* Fulminant hepatic failure,\n* Neurogenic shock.\n* Adult under legal protection (guardianship, curatorship, or judicial protection).","18 Years",{"count":55,"type":20},2500,"OBSERVATIONAL","Mixed cardiogenic-vasoplegic shock (M-CS) represents a distinct and severe phenotype of cardiogenic shock characterized by concomitant myocardial dysfunction and inappropriate systemic vasodilation. Despite its clinical relevance, the epidemiology, management, and outcomes of M-CS remain poorly defined.\n\nThis retrospective, multicenter, observational registry aims to evaluate the clinical outcomes and prognostic factors associated with mixed cardiogenic-vasoplegic shock. The study will analyze clinical, biological, and invasive hemodynamic data routinely collected during patient management for M-CS.\n\nAll included patients will have been admitted for cardiogenic shock, with or without vasoplegia, defined by low cardiac output and, when present, decreased systemic vascular resistance despite adequate filling pressures requiring vasopressor support.\n\nThe primary objective is to describe mortality and organ failure rates, while secondary analyses will identify determinants of adverse outcomes and potential phenotypic subgroups.\n\nThe PROMIX registry will be conducted across three French university hospitals (CHU Amiens-Picardie, CHU Dijon-Bourgogne, and CHU Rouen-Normandie).\n\nThis study is non-interventional, involving only data obtained as part of routine critical care, and will provide the first multicenter overview of this complex and underrecognized form of cardiogenic shock.",[59,26,60,61,62,63],"Cardiogenic Shock Acute","Septic Shock","Mechanical Circulatory Support","Myocardial Infarction (MI)","Cardiogenic Shock Post Myocardial Infarction",[65,66,61,67,68,69],"VA-ECMO","Cardiogenic Shock","Vasopressor","Mixed Cardiogenic Shock","post cardiotomy shock","RECRUITING","2026-01-15",{"date":73,"type":36},"2026-01-21",{"date":75,"type":36},"2025-10-20",{"date":77,"type":20},"2027-06-01",{"name":79,"class":43},"Centre Hospitalier Universitaire, Amiens",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":17,"minAge":53,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":21,"phases":92,"briefSummary":93,"conditions":94,"keywords":98,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":113},"100617093","multivessel-minimally-invasive-coronary-bypass-grafting-as-hybrid-revascularization-versus-conventional-off-pump-coronary-artery-bypass-grafting-100617093","NCT07314138","Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-pump Coronary Artery Bypass Grafting","MICRA-HYBRID Trial: A Randomized Controlled Trial of 'Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-Pump Coronary Artery Bypass Grafting'","MICRA-HYBRID","Inclusion Criteria:\n\n* Patients with three-vessel disease (either angiographic stenoses \\>70% or a fractional flow reserve value ≤0.80)\n* Left main diameter stenosis ≥50% or a left main intravascular ultrasound minimal luminal area of ≤4.5 mm2 or fractional flow reserve value ≤0.80 combined with significant CAD of the right coronary artery\n\nExclusion Criteria:\n\nA potential participant who meets any of the following criteria will be excluded from participation in this study:\n\n* Age \\\u003C 18 or \\> 85 years\n* Chronic total occlusion of the RCA\n* In-stent RCA restenosis\n* RCA stenosis with high-risk clinical features requiring urgent PCI or surgical revasculari-zation.\n* Reverse hybrid coronary revascularization, defined as PCI-RCA followed by surgical re-vascularization.\n* Acute cardiac ischemia necessitating immediate intervention.\n* EF \\\u003C 30 %\n* eGFR \\\u003C 30 ml\u002Fmin\n* Indication for concomitant cardiac surgery (e.g. valve or arrhythmia surgery) or non-cardiac surgery\n* Previous thoracic or cardiac surgery, mediastinal irradiation, significant trauma to the chest\n* Preoperative severe end-organ dysfunction (dialysis, liver failure, respiratory failure) or cancer.\n* Hemodynamically significant left subclavian stenosis\n* Severe chest wall deformities\n* History of pericarditis\n* Body mass index \\> 40 Kg\u002Fm2.",true,"85 Years",{"count":91,"type":20},250,[23],"The MICRA-HYBRID trial is a prospective, multicenter, randomized controlled study comparing multivessel hybrid coronary revascularization (HCR) as minimally invasive arterial bypass grafting to left-sided coronary targets (LAD and LCx) plus PCI of the RCA versus conventional off-pump coronary artery bypass grafting (OPCAB) via median sternotomy in patients with three-vessel coronary artery disease. The primary goal is to evaluate whether multivessel-HCR provides superior 30-day \"textbook\" clinical outcomes (mortality, MI, stroke, re-exploration for bleeding, and other complications) while improving perioperative recovery and long-term cardiovascular outcomes.",[95,26,96,97],"Coronary Artery Disease (CAD)","Minimally Invasive Coronary Revascularization Surgery","Off-pump Coronary Artery Bypass",[99,100,101,102,103],"minimally invasive coronary surgery","percutaneous coronary intervention","off-pump coronary artery bypass grafting","hybrid coronary revascularization","heart surgery","2025-12-23",{"date":106,"type":36},"2026-01-02",{"date":108,"type":20},"2026-04-01",{"date":110,"type":20},"2034-05-01",{"name":112,"class":43},"Catharina Ziekenhuis Eindhoven",2]