[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"capnography\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:capnography":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,69,90],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100642290","transnasal-microstream-etco2-reduces-hypoxemia-during-emergence-in-aged-post-abdomen-surgery-100642290",false,"NCT07652385","Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery","Effect of Transnasal Microstream Capnography on Incidence of Hypoxemia During Emergence From General Anesthesia in Elderly Patients After Abdominal Surgery: A Prospective Randomised Controlled Trial","Inclusion Criteria:\n\n* Age 65-80 years;\n* ASA physical status I-III;\n* BMI 18-30 kg\u002Fm²;\n* Participants scheduled for elective laparoscopic surgery under general anesthesia with endotracheal intubation;\n* Willing to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n* Patients with nasal bleeding, nasal mucosal injury, nasal cavity occupancy, or other conditions that preclude transnasal carbon dioxide monitoring;\n* Patients undergoing emergency surgery;\n* Participants requiring postoperative assisted ventilation via endotracheal intubation or tracheostomy;\n* Presence of any disease or condition that may cause abnormal end-tidal carbon dioxide waveforms or abnormal baseline pulse oximetry (e.g., congenital heart disease or chronic lung disease);\n* Severe cardiac insufficiency (≤4 Metabolic Equivalents \\[MetS\\]);\n* Severe renal insufficiency (acute kidney injury \\[AKI\\] or chronic kidney disease \\[CKD\\] stage 4 or higher);\n* Severe hepatic insufficiency (Child-Pugh class C or worse);\n* Allergy to study medications;\n* Daily alcohol intake ≥60 grams;\n* History of psychiatric disorders such as depression, severe central nervous system depression, Parkinson's disease, basal ganglion lesions, schizophrenia, epilepsy, Alzheimer's disease;\n* Participation in another related clinical study within the past 3 months.",true,"ALL","65 Years","80 Years",{"count":21,"type":22},324,"ESTIMATED","INTERVENTIONAL",[25],"NA","This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia in elderly patients (65-80 years, ASA I-III, BMI 18-30 kg\u002Fm²) undergoing elective laparoscopic surgery under general anesthesia with endotracheal intubation. A total of 324 patients will be randomized 1:1 to either the control group (standard SpO₂ monitoring and clinical observation with oxygen delivery at 2 L\u002Fmin via sampling line) or the experimental group (same oxygen delivery plus continuous real-time transnasal microstream EtCO₂ monitoring). The primary outcome is the incidence of hypoxemia (SpO₂ \\\u003C 90% for \\>15 seconds) after extubation in the PACU. Secondary outcomes include severe hypoxemia (SpO₂ \\\u003C 85%), lowest SpO₂ during PACU stay, vital signs at specified time points, PACU length of stay, and other adverse events. Statistical analysis will use chi-square or Fisher's exact test for the primary outcome, with a sample size calculated to detect a reduction in hypoxemia from 33% (control) to 18% (experimental group) (α=0.05, power=80%, plus 20% dropout).",[28,29,30,31],"Elderly Patients","Laparoscopic Surgery","Postoperative Hypoxemia","Capnography","NOT_YET_RECRUITING","2026-06-16",{"date":35,"type":36},"2026-06-17","ACTUAL",{"date":38,"type":22},"2026-07-01",{"date":40,"type":22},"2028-10-01",{"name":42,"class":43},"Jianbo Wu","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":4},"100580330","trending-ability-of-end-tidal-capnography-to-reflect-arterial-carbon-dioxide-changes-in-one-lung-ventilation-100580330","NCT06835894","Trending Ability of End-Tidal Capnography to Reflect Arterial Carbon Dioxide Changes in One-Lung Ventilation","Do End-Tidal Capnography Trends Reflect Changes in Arterial Carbon Dioxide Partial Pressure During One-Lung Ventilation for Thoracoscopic Surgery? A Prospective Observational Study","Inclusion Criteria:\n\n* Patients undergoing thoracoscopic lung surgery with one-lung ventilation\n* Patients requiring invasive arterial blood pressure monitoring\n\nExclusion Criteria:\n\n* Chronic obstructive pulmonary disease (COPD)\n* Pulmonary hypertension\n* Systemic infection","18 Years",{"count":53,"type":22},115,"OBSERVATIONAL","In this study, we want to find out if measuring carbon dioxide from a patient's breath (end-tidal CO₂ or ETCO₂) can reliably reflect changes in blood carbon dioxide levels (arterial CO₂ or PaCO₂) during lung surgery. Instead of just looking at individual values, we are specifically investigating whether ETCO₂ and PaCO₂ rise and fall in the same direction over time.\n\nDuring lung surgery, patients often need \"one-lung ventilation,\" where only one lung is used for breathing while the other is deflated to help the surgeon. This can cause carbon dioxide levels in the blood to change, which are typically monitored by taking blood samples. If ETCO₂ trends closely follow PaCO₂ trends, doctors may not need to take as many blood samples.\n\nPatients in this study will already have a small tube in an artery for monitoring blood pressure. Whenever a blood test is taken, we will compare the blood CO₂ level with the ETCO₂ reading at that moment. We will also track heart rate, blood pressure, and body temperature.\n\nBy comparing these measurements, we hope to learn whether ETCO₂ reliably follows the same trends as PaCO₂, making it a useful tool for monitoring carbon dioxide levels in lung surgery with fewer blood tests.",[57,58,31,59],"Video-Assisted Thoracoscopic Surgery","One-Lung Ventilation","Blood Gas Analysis","2025-02-14",{"date":62,"type":36},"2025-02-19",{"date":64,"type":22},"2025-04-01",{"date":66,"type":22},"2025-07-10",{"name":68,"class":43},"Koç University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":16,"sex":76,"minAge":51,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":4},"100579462","the-effect-of-oxygen-flow-rate-on-end-tidal-co2-during-deep-sedation-100579462","NCT06824610","The Effect of Oxygen Flow Rate on End-tidal CO2 During Deep Sedation","The Effect of Different Oxygen Flow Rates on End-tidal Carbon Dioxide Monitoring During Procedural Sedation in Patients Undergoing Minor Gynaecological Procedures.","Inclusion Criteria:\n\n1. Patient aged 18-45 years\n2. ASA physical status l : ll\n3. Minor elective gynaecological procedures lasting less than 30 minutes ( D\\&C biopsy, hysteroscopic polypectomy and diagnostic hysteroscopy )\n\nExclusion Criteria:\n\n* We will exclude from the study patients with the following:\n\n  1. Patient refusal to participate in this study.\n  2. ASA lll or more.\n  3. Lengthy procedures taking more than 30 minutes\n  4. Contraindication for the use of laryngeal mask airway as ( pharyngeal pathology, risk of aspiration and airway obstruction below larynx)\n  5. BMI more than 35","FEMALE","45 Years",{"count":79,"type":22},120,"This study aims to detect the effect of different O2 flow rates on end tidal carbon dioxide level in patients scheduled for minor gynaecological procedures under deep sedation using laryngeal mask airway.\n\n* Primary outcome was measuring end tidal carbon dioxide ( EtCO2 ) non invasively by laryngeal mask all through the procedure.\n* Secondary outcomes included peripheral O2 saturation, hemodynamics, time to recovery, total propofol dose, patients' satisfaction, sedation score, and complications.",[31],"2025-02-12",{"date":60,"type":36},{"date":85,"type":22},"2025-03-01",{"date":87,"type":22},"2025-09-20",{"name":89,"class":43},"Minia University",{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":4,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":116},"100502100","diagnostic-accuracy-of-capnography-in-nasogastric-tube-placement-100502100","NCT05817864","Diagnostic Accuracy of Capnography in Nasogastric Tube Placement","Diagnostic Accuracy of Using Capnography in Verification of Nasogastric Tube Placement in Hospital Settings","Inclusion Criteria:\n\n* 18 years old or above;\n* Admitted to the general medical and geriatric wards, ICUs, or subacute\u002Frehabilitation\u002Finfirmary wards in subacute\u002Fconvalescent\u002Fextended care hospitals or visiting AEDs in acute hospitals;\n* Requiring the insertion of an nasogastric tube into the stomach for assessment, nutritional support and medication administration during the study period.\n\nExclusion Criteria:\n\n* Participants receiving life-saving intervention at the time of recruitment.",{"count":98,"type":22},390,"A prospective observational diagnostic study will be conducted to assess the sensitivity and specificity of using capnography in detecting the correct placement of nasogastric tubes using the reference standards of radiography and measurement of aspirates for pH value.",[31,101,102],"Nasogastric Tube","Diagnostic Accuracy",[31,104,105],"Intubation, gastrointestinal","Diagnostic accuracy","RECRUITING","2024-09-02",{"date":109,"type":36},"2024-09-05",{"date":111,"type":36},"2023-07-01",{"date":113,"type":22},"2025-12",{"name":115,"class":43},"Chinese University of Hong Kong",1]