[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiac-disease-pulmonary-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiac-disease-pulmonary-disease":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100605067","advanced-respiratory-monitoring-and-oxygen-therapy-in-chronically-ill-patients-with-acute-respiratory-failure-100605067",false,"NCT07157696","Advanced Respiratory Monitoring and Oxygen Therapy in Chronically Ill Patients With Acute Respiratory Failure","Advanced Bedside Lung Imaging and Respiratory Muscle Monitoring for Respiratory Support Management in Chronically Ill Patients With Acute Respiratory Failure: From Hospital to Home","HOME- Oxygen","Inclusion Criteria: Adults (≥18 years) with chronic respiratory (e.g., COPD, interstitial lung disease) and\u002For cardiac disease (e.g., heart failure), Clinical indication for long-term oxygen therapy, Capability to manage home-based devices independently or with caregiver assistance Signed informed consent\n\nExclusion Criteria:\n\nLife expectancy \\\u003C 3 months Inability to comply with home follow-up procedures.","ALL","18 Years","80 Years",{"count":21,"type":22},16,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study is testing whether a new type of home oxygen therapy, called high-flow nasal cannula (HFNC), can improve breathing comfort and quality of life for people with long-term lung or heart conditions who need oxygen after leaving the hospital.\n\nHFNC delivers warm, humidified oxygen at higher flow rates than standard oxygen therapy, which may reduce shortness of breath, improve sleep, and make daily activities easier. The therapy will be provided using the myAirvo™3 device, which also allows doctors to check patients' oxygen levels, heart rate, and symptoms remotely. All patients will also wear a small device (RootiREX) to monitor heart rhythm, sleep quality, and detect breathing pauses at night.\n\nParticipants will try both treatments - HFNC and standard oxygen therapy - for short periods, in random order, so that researchers can directly compare the effects within the same patient. Each treatment period will last two weeks, with a short break in between.\n\nThe main goal of the study is to see whether HFNC reduces shortness of breath (measured by the modified Medical Research Council scale). Other outcomes include comfort, sleep quality, quality of life, oxygen levels, and how well patients are able to use the devices at home.\n\nThe study will last six weeks in total for each participant. Researchers expect that HFNC will improve breathing comfort, stabilize oxygen levels, and reduce the need for hospital visits during this time.",[28,29,30],"Chronic Respiratory Failure","Cardiac Disease, Pulmonary Disease","Acute Respiratory Failure (ARF)","NOT_YET_RECRUITING","2025-10-02",{"date":34,"type":35},"2025-10-03","ACTUAL",{"date":34,"type":22},{"date":38,"type":22},"2027-01-30",{"name":40,"class":41},"Università degli Studi di Ferrara","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100566901","exploratory-study-of-the-diagnostic-potential-of-an-innovative-thoracic-vibration-analysis-technique-100566901","NCT06661200","Exploratory Study of the Diagnostic Potential of an Innovative Thoracic Vibration Analysis Technique","Exploratory Study of the Diagnostic Potential of an Innovative Thoracic Vibration Analysis Technique for Detecting Pulmonary and\u002For Cardiac","AIRFORCE2","Inclusion Criteria:\n\n* Cardiac disease OR respiratory failure OR healthy volunteer\n* Affiliate to the social security system\n* French-speaking\n* Patient having been informed of the study and having signed informed\n\nExclusion Criteria:\n\n* consent.BMI \\\u003C 17 or BMI \\> 35\n* Patients unable to stand for more than 10 minutes\n* Patients unable to remain in apnea for 15 - 20 seconds\n* Breast prosthesis wearers\n* Wearers of pacemakers and\u002For defibrillators\n* Valve prosthesis wearers\n* Patients with difficulty understanding simple instructions (inspiration, expiration, respiratory blockage)\n* Patients with severe hearing problems.\n* Pregnant or breastfeeding woman. A urine pregnancy test will be performed if necessary.",true,{"count":52,"type":22},270,[25],"Heart and lung disease are two major causes of hospitalisation and mortality in France (4-8). Together, these two diseases affect several million people in France, either acutely or chronically. They represent a major public health problem in social and economic terms.\n\nDiagnosis of these disorders is often delayed, with acute decompensation preceded by a period of frustrating, non-specific clinical signs (9-12), which delay their discovery. Screening for these conditions in their early stages or diagnosing them in their acute form is crucial, but remains difficult because it requires multiple investigations that are costly and time-consuming (biology, radiology, ECG, etc.). The difficulty of diagnosis, the progressive profile and the ever-increasing frequency of these conditions (environmental and socio-economic factors) have considerably altered the landscape of medical emergencies and contributed to their difficulty.\n\nThe availability of a non-invasive technique capable of diagnosing both cardiac and pulmonary disorders without the help of an expert, without direct contact with the patient and without requiring his or her active participation, would be a major advance.\n\nTechnological innovations in all fields have always helped to improve patient care.The recent emergence of telemedicine and POCT(US) connected objects (point of care testing, point of care ultrasound)(13,14) is a good illustration of this.\n\nA new technique using ultrasound, developed by the Langevin Institute (Surface Camera Motion) and supported by the start-up Austral Diagnostics, makes it possible, without direct contact with the subject, to record the propagation of thoracic vibrations induced by the functioning of the heart pump and respiratory mechanics.Consequently, any anomaly in the functioning of these organs can cause a change in the thoracic vibration regime and its propagation.\n\nThis completely new technique for exploring thoracic vibrations provides a particularly rich signal that has not yet been explored. Under these conditions, the signatures associated with cardiac and\u002For pulmonary pathologies are not yet perfectly defined.Furthermore, the diagnostic potential of this new technique in the early or acute phases of cardiopulmonary pathologies remains to be assessed.\n\nIn this prospective study, we propose to explore the signatures produced by this signal in various cardiac and respiratory pathologies.\n\nThe aim is To identify the discriminating criteria of the SMC signal that enable cardiac and pulmonary pathologies to be detected compared with a group of healthy subjects.",[29],[57],"ultrasound, surface motion camera, sismography","RECRUITING","2024-10-24",{"date":61,"type":35},"2024-10-28",{"date":63,"type":35},"2024-05-17",{"date":65,"type":22},"2026-02-14",{"name":67,"class":41},"University Hospital, Caen",1]