[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiac-output-low\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiac-output-low":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100636649","correlation-of-cardiac-index-measured-by-the-pram-method-with-nirs-and-lactate-levels-in-pediatric-aortic-coarctation-surgery-100636649",false,"NCT07568431","Correlation of Cardiac Index Measured by the PRAM Method With NIRS and Lactate Levels in Pediatric Aortic Coarctation Surgery","Correlation of Cardiac Index Measured by the Pressure Recording Analytical Method (PRAM) With Near-Infrared Spectroscopy (NIRS) and Arterial Lactate Levels in Neonates and Infants Undergoing Surgical Repair of Aortic Coarctation: A Prospective Observational Study","MostCare-Ped","Inclusion Criteria:\n\n* Neonates and infants planned for surgical repair of aortic coarctation\n* Body weight between 2.5 and 3.5 kg\n* Postnatal age between 0 and 3 months\n* Considered hemodynamically stable for anesthesia and surgery\n* Written informed consent obtained from legal guardians\n\nExclusion Criteria:\n\n* Severe multiorgan dysfunction\n* Additional major congenital heart defect (e.g., Tetralogy of Fallot, Transposition of Great Arteries, Hypoplastic Left Heart Syndrome)\n* Surgery requiring cardiopulmonary bypass\n* Preoperative metabolic acidosis or sepsis\n* Inability to obtain informed consent from legal guardians","ALL","3 Months",{"count":20,"type":21},43,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the correlation between cardiac index measured by the MostCare™ system (Pressure Recording Analytical Method, PRAM) and cerebral\u002Frenal regional oxygen saturation measured by near-infrared spectroscopy (NIRS) and arterial lactate levels in neonates and infants (body weight 2.5-3.5 kg, age 0-3 months) undergoing surgical repair of aortic coarctation. Measurements will be recorded at four intraoperative time points: after anesthesia induction, before aortic cross-clamp, 3 minutes after cross-clamp release, and at end of surgery. No additional intervention beyond standard anesthesia and surgical care will be applied.",[25,26],"Aortic Coarctation","Cardiac Output, Low",[28,29,30,31,32,25],"PRAM","Near-Infrared Spectroscopy","Cardiac Index","Pediatric Cardiac Surgery","Lactate","NOT_YET_RECRUITING","2026-04-28",{"date":36,"type":37},"2026-05-05","ACTUAL",{"date":39,"type":21},"2026-05",{"date":41,"type":21},"2027-03",{"name":43,"class":44},"Konya City Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":45},"100420515","effect-of-labetalol-atenolol-and-nifedipine-on-maternal-hemodynamics-measured-by-icg-in-early-pregnancy-100420515","NCT04755764","Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy","The Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by Impedance Cardiography in Early Pregnancy","Inclusion Criteria:\n\n* Patients presenting to Maternal Hypertension Center at Cabell Huntington Hospital\n* English speaking\n* 18-45 years old.\n* Willing to provide informed consent\n* Gestational age prior to 15 weeks gestation\n\nExclusion Criteria:\n\n* Non-English speaking patients, patients\n* \\\u003C18 years old or \\>45 years old\n* Not willing or able to provide consent\n* Gestational age \\>15 weeks",true,"FEMALE","18 Years","45 Years",{"count":58,"type":21},60,"The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy. Patients will be given medication based on their hemodynamics and asked to return for a repeat measurement.",[61,62,63,26,64],"Systolic Hypertension","Pregnancy Related","Diastolic Hypertension","Cardiac Output, High","RECRUITING","2025-05-09",{"date":68,"type":37},"2025-05-13",{"date":70,"type":37},"2021-03-03",{"date":72,"type":21},"2025-12",{"name":74,"class":44},"Marshall University",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":45},"100367430","non-invasive-continuous-cardiac-output-monitoring-in-preterm-infants-study-100367430","NCT04064177","Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study","NICCOM","Inclusion Criteria:\n\n* Healthy term infants in postnatal ward (within the first 72 hours of age)\n* Term and Preterm infants (including those with FGR) admitted to the neonatal unit\n* Written informed parental consent (prospective for postnatal ward and retrospective for babies admitted to the neonatal units)\n\nExclusion Criteria:\n\n* Antenatal or postnatal diagnosis of severe congenital anomaly\n* Infants with no realistic chance of survival\n* Infants who are \\>12 hours of age\n* Infants with fragile skin not permitting skin probe placement","1 Hour","40 Weeks",{"count":85,"type":21},148,"This is an observational study in newborn term and preterm infants. The study will validate if non-invasive continuous cardiac output monitoring is feasible in newborn infants, if normative values can be constructed and what is the effect of fluid boluses and inotropes on cardiac output and peripheral vascular resistance.",[26,64,88],"Blood Pressure",[88],"2024-07-26",{"date":92,"type":37},"2024-07-29",{"date":94,"type":37},"2019-10-24",{"date":96,"type":21},"2024-12-31",{"name":98,"class":44},"Imperial College Healthcare NHS Trust"]