[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiac-output\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiac-output":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,53,82,104,131],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100643703","bedside-assessment-of-right-ventricular-output-lying-in-prone-or-supine-position-100643703",false,"NCT07632027","Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine Position","The BAROLO Study Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine Position. Hemodynamic Changes Due to Prone Position in Patients After Cardiac Surgery - a Prospective Randomized Controlled Trial Evaluating the Effect of Prone Position on Right Heart Function","BAROLO","Inclusion Criteria:\n\n* Scheduled for cardiac surgery using cardiopulmonary bypass\n\nExclusion Criteria:\n\n* BMI \\>40\n* Emergency surgery\n* In need of secondary surgery\n* Advanced grown up congenital heart disease\n* Pulmonary disease\n* Hemodynamic instability with Norepinephrine \\>0.4mcg\u002Fkg\u002Fmin\n* Any condition which, in the judgement of the investigator, might increase the risk to the patient","ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay. The right ventricle is particularly vulnerable to an increased afterload. By increasing pulmonary vascular resistance (PVR), atelectasis might mitigate a negative effect on the right ventricle.\n\nRecruitment maneuvers have been shown to resolve atelectasis and improve hemodynamics by increasing cardiac output and lowering PVR. However these maneuvers transiently raise airway pressures, which in turn increases right ventricular afterload, a situation often poorly tolerated by patients with RVF.\n\nProne position is used in patients with respiratory failure and has been shown to decrease mortality in patients with ARDS. Prone position decreases atelectasis and moves ventilation dorsally. In ARDS it also seems to mediate beneficial hemodynamic effects such as an increase in cardiac output and a decrease in PVR.\n\nThe investigators hypothesis is that prone position early after cardiac surgery will increase cardiac output by recruitment of atelectasis and thereby decrease PVR.",[27,28,29,30,31,32,33,34,35,36,37,38,39],"Right Ventricular Function","Prone Position","Atelectasis","Atelectases, Postoperative Pulmonary","Cardiac Output","Vasoconstriction","Heart Failure","Recruitment Maneuver","Respiratory Mechanics","Pulmonary Arterial Pressure","Cardiac Surgery","Cardiac Surgery Recovery","Cardiopulmonary Bypass","NOT_YET_RECRUITING","2026-06-03",{"date":43,"type":44},"2026-06-08","ACTUAL",{"date":46,"type":21},"2026-09",{"date":48,"type":21},"2028-10",{"name":50,"class":51},"Sahlgrenska University Hospital","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":66,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":52},"100599268","short-term-atrial-pacing-and-hemodynamics-after-cardiac-surgery-100599268","NCT07082283","Short-Term Atrial Pacing and Hemodynamics After Cardiac Surgery","STAPH-CS Study: Short-Term Atrial Pacing and Hemodynamics After Cardiac Surgery - A Prospective Randomized Evaluation of Variable-Rate Atrial Stimulation After Cardiac Surgery With Cardiopulmonary Bypass","STAPH-CS","Inclusion Criteria:\n\n* Patients aged 18 years or older\n* Cardiac surgery under CPB (coronary artery bypass grafting, valve replacement or repair, or combined procedures)\n* Placement of epicardial atrioventricular pacing wires during surgery\n* Placement of a Swan-Ganz catheter intraoperatively\n* Signed informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Patients with an internal pacemaker\n* History of permanent atrial fibrillation\n* Complete atrioventricular block upon weaning from CPB\n* Junctional rhythm upon weaning from CPB\n* Sinus rhythm \\\u003C 50 bpm upon weaning from CPB\n* Failure of atrial or dual-chamber pacing (patients paced in ventricular mode VVI)\n* Contraindication to Swan-Ganz catheter placement\n* Hemodynamic instability defined by significant bleeding or tamponade requiring surgical re-intervention, or the need for escalating doses of vasopressors (Norepinephrine \\> 1 μg\u002Fkg\u002Fmin, Dobutamine \\> 10 μg\u002Fkg\u002Fmin)",{"count":62,"type":21},200,[24],"The goal of this clinical trial is to learn whether temporary atrial pacing improves heart function after cardiac surgery under cardiopulmonary bypass (CPB). It will also help determine the best pacing rate during the first 24 hours after surgery. The main questions it aims to answer are:\n\n* Does atrial pacing improve cardiac output after surgery?\n* Is 70, 80, or 90 bpm the most effective pacing rate?\n* Does pacing reduce the risk of atrial fibrillation after surgery?",[31],[67,68,69,70,71],"Cardiopulmonary bypass","Temporary atrial pacing","Pacing frequency","Hemodynamic profile","Cardiac output","RECRUITING","2025-08-15",{"date":75,"type":44},"2025-08-17",{"date":77,"type":44},"2025-08-04",{"date":79,"type":21},"2026-09-30",{"name":81,"class":51},"Saint-Joseph University",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":89,"targetDuration":91,"studyType":92,"phases":4,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":4},"100588245","study-on-cardiac-output-evaluation-based-on-wearable-monitoring-data-100588245","NCT06938893","Study on Cardiac Output Evaluation Based on Wearable Monitoring Data","Inclusion Criteria:\n\n* Over 18 years old\n* Left ventricular ejection fraction (Left ventricular ejection fraction, LVEF) \\\u003C 50%(200 subjects)\n* Left ventricular ejection fraction (Left ventricular ejection fraction, LVEF) ≥50% (100 subjects)\n* Able to use smart phones and operate wearable devices such as wristbands\u002Fwatches\n\nExclusion Criteria:\n\n* Patients with pacemaker implantation\n* No smartphone\n* Currently participating in other clinical trials\n* Lactating women\n* Pregnant Women\n* Unable to run and ride due to personal physical and external reasons (subjects participating in the exercise state cardiac output model study)\n* Physical examination results in the past year have clear cardiovascular, metabolic, bone and joint related diseases that have exercise risk, or have diseases and related potential health risks confirmed by the self-examination form of physical status before exercise (participants in the exercise state cardiac output model study)\n* No informed consent was obtained",true,{"count":90,"type":21},300,"1 Month","OBSERVATIONAL","Based on the monitoring data of wearable devices, with cardiac output (CO) as the gold standard, this study intends to develop a non-invasive evaluation model of CO based on wearable data, and optimize the parameters to realize the cardiac capacity detection function in resting and exercise states on the wearable device.",[31],"2025-04-14",{"date":97,"type":44},"2025-04-22",{"date":99,"type":21},"2025-04-20",{"date":101,"type":21},"2026-12-31",{"name":103,"class":51},"Navy General Hospital, Beijing",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":88,"sex":111,"minAge":18,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":115,"briefSummary":116,"conditions":117,"keywords":120,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":52},"100558442","heat-acclimation-in-females-100558442","NCT06551168","Heat Acclimation in Females","The Cardiovascular, Hematological, and Performance Response to Heat Acclimation in Healthy Trained Females","Inclusion Criteria:\n\n* Familiar with the sport of cycling and own a bicycle and smart trainer (or a trainer and a power meter).\n* Endurance athlete or currently engaging in endurance exercise\n* Maximal oxygen consumption (VO2max) greater than 40 ml\u002Fkg\u002Fmin\n* Between the ages of 18 and 55\n* Able to speak, read, and write in English\n\nExclusion Criteria:\n\n* Unable to exercise\n* Previous or current heat intolerance\n* Pregnant","FEMALE","55 Years",{"count":114,"type":21},14,[24],"Heat acclimation is when you repeatedly exposure yourself to heat so that your body adapts and better tolerates heat.\n\nThis project will determine if completing a heat acclimation maintenance period after heat acclimation is more beneficial than heat acclimating alone for exercise performance in the heat. To determine this, participants will exercise in the heat before heat acclimation, after heat acclimation, and after heat acclimation maintenance. Researchers will assess the heart's pumping capacity, blood volume, body temperature, and exercise performance to determine which approach is more effective.",[118,119,31],"Heat Exposure","Blood Volume",[121],"basic science","2025-04-07",{"date":124,"type":44},"2025-04-10",{"date":126,"type":44},"2024-09-01",{"date":128,"type":21},"2026-04-24",{"name":130,"class":51},"Trinity Western University",{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":22,"phases":139,"briefSummary":140,"conditions":141,"keywords":144,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":52},"100583703","optimization-of-patient-preparation-and-imaging-techniques-for-cardiac-ct-100583703","NCT06879769","Optimization of Patient Preparation and Imaging Techniques for Cardiac CT","Inclusion Criteria:\n\n* Participant with a preexisting referral for a Cardiac CT examination\n* Age 18 years or older\n\nExclusion Criteria:\n\n* Age under 18 years\n* Atrial fibrillation\n* Pacemaker\n* Participation in clinical drug trials\n* Contraindications to beta-blockers\n* Severe medical conditions\n* Challenges in comprehending study information\n* Pregnancy",{"count":138,"type":21},240,[24],"The goal of this clinical trial is to compare four different methods of reducing heart rate before cardiac imaging. The diagnostic imaging technique used in this study is called Computed Tomography (CT) of the coronary vessels (CCTA). Globally, approximately one-third of patients experience heart-related conditions. Because the heart is a moving organ, imaging presents challenges. A higher heart rate requires increased scanning power, which results in more images and, in some cases, higher radiation exposure that may be harmful. To address this issue, beta-blocker medication is administered before the examination to lower the heart rate. This medication can be given orally, intravenously, or both. While this approach is effective, the most optimal method remains uncertain.\n\nThe objectives of this study are:\n\n* To determine whether oral administration of beta-blockers is as effective as intravenous administration in maintaining a stable heart rate during CT imaging.\n* To assess whether listening to music during the procedure improves patient comfort and overall experience.\n\nParticipants will:\n\n* Be randomly assigned to one of four groups:\n* One group will receive beta-blocker medication orally.\n* Another group will receive beta-blocker medication intravenously.\n* One group will listen to music during the procedure. Participants will report their sensations and experiences before, during, and after the examination.\n\nThe study investigators will compare the effectiveness of oral and intravenous beta-blockers, as well as the impact of music, in terms of:\n\n* Heart rate stability and reduction.\n* Participant-reported comfort and overall experience.",[142,143,31],"Coronary Computed Tomography Angiography","Contrast Media",[145,31,146,147,148],"Music intervention","CCTA","Beta blockers","Metoprolol","2025-03-14",{"date":151,"type":44},"2025-03-17",{"date":153,"type":44},"2021-01-01",{"date":155,"type":21},"2027-12-01",{"name":157,"class":51},"Karolinska University Hospital"]