[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiac-pacing-artificial\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiac-pacing-artificial":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100611865","leadless-pacemaker-registry-outcomes-and-follow-up-from-the-university-hospital-of-st-plten-100611865",false,"NCT07246135","Leadless Pacemaker Registry: Outcomes and Follow-up From the University Hospital of St. Pölten","Leadless Pacemaker Registry","LPR","Inclusion Criteria:\n\n* Patients undergoing implantation of a leadless pacemaker at the University Hospital of St. Pölten\n* Patients who previously received a leadless pacemaker between June 2015 and the start of the registry (retrospective inclusion).\n* Age ≥ 18 years.\n* Written informed consent provided by the patient.\n\nExclusion Criteria:\n\n* Patients who decline or are unable to provide informed consent.\n* Patients in whom a conventional transvenous pacemaker is implanted (i.e., not leadless).\n* Any condition that, in the opinion of the treating physician, precludes participation in the registry.","ALL","18 Years",{"count":20,"type":21},700,"ESTIMATED","OBSERVATIONAL","The registry for leadless pacemakers will collect and annually analyze the data of all leadless pacemaker implantations at the University Hospital St. Pölten, including demographic information, indications, procedural details, acute, medium- and long-term complications during follow-up. Due to the partially novel nature of the signals (atrial mechanical sensing markers) and the lack of long-term experience to date, data on these aspects will also be collected and analyzed.\n\nThis is a single-center, prospective and retrospective registry that includes all patients receiving a leadless pacing device, as well as all patients who received a leadless pacing device between January 2021 and the start of the registry. All patients undergoing implantation of a leadless pacemaker will be invited to participate in the registry. For patients to be included retrospectively, participation in the registry will be offered at the time of their next routine follow-up visit.\n\nThe indication for leadless pacing will be determined by the physician responsible for the patient. Enrollment in the registry will in no case alter or influence the treatment the patient receives. Data collection will take place at the time of implantation and continuously during follow-up over the entire study period. Pacemaker-related data may be obtained either in person or via remote monitoring.",[25,26,27,28],"Pacemaker","Leadless Pacemaker","Cardiac Pacing, Artificial","Registries",[30,26,25,31,32,33,34,35],"Registry","Cardiac Pacing","Pacemaker Complication","Leadless Pacemaker Outcomes","Heart Conduction System Disease","Bradycardia","RECRUITING","2025-11-17",{"date":39,"type":40},"2025-11-24","ACTUAL",{"date":42,"type":40},"2015-06-18",{"date":44,"type":21},"2035-01",{"name":46,"class":47},"Karl Landsteiner University of Health Sciences","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":58,"studyType":22,"phases":4,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":48},"100586376","cardiac-implantable-electronic-device--induced-remodelling-of-tricuspid-valve-and-right-chambers-100586376","NCT06914570","Cardiac Implantable Electronic Device- Induced Remodelling of Tricuspid Valve and Right Chambers","CIED-REMTRIC","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patient able and willing to give informed consent in written form before the index procedure\n* Patient understands the purpose, the potential risks as well as benefits of the study and is willing to participate in all parts of the follow-up\n* Patients undergoing any new CIED implantation with or without transvalvular lead\n* Sufficient imaging quality on transthoracic echocardiography to assess TR severity grade and morphology of right-sided heart chambers\n\nExclusion Criteria:\n\n* Previous or present CIED\n* Life expectancy \\\u003C 12 months due to non-cardiac condition\n* Tricuspid valve stenosis of any severity or severe TR planned for intervention (transcatheter, surgical) within the next 12 months\n* Previous tricuspid valve intervention (transcatheter, surgical)\n* Participation in another study, which would lead to deviations from this trial protocol",{"count":57,"type":21},350,"5 Years","This single-center longitudinal study aims to evaluate the occurrence and clinical impact of tricuspid regurgitation (TR) after cardiac-implanted-electronic-device (CIED) implantation by comprehensive echocardiographic assessment, including advanced three-dimensional (3D) transthoracic and transesophageal imaging.\n\nThe primary objective of this study is to assess the prevalence and leading mechanism of new or worsening TR, defined as an increase of at least one grade on a five-grade scale, after new CIED implantation.\n\nSecondary objectives include clinical and echocardiographic endpoints at discharge, three months, one year, and annually for up to five years.\n\nThey can be summarized as follows:\n\n1. to evaluate morphological and functional changes (remodeling) of the tricuspid valve (TV) apparatus and right-sided heart chambers in patients undergoing new CIED implantation.\n2. to identify risk factors for new or worsening TR after CIED implantation on an anatomical, procedural, and clinical level.\n3. to determine the clinical impact of new or worsening TR after CIED implantation.\n4. to explore the treatment strategies for lead-related TR (observational).",[27,61],"Tricuspid Valve Regurgitation, Non-rheumatic",[63,64,65,66],"Cardiac Implantable Electrical Devices","Tricuspid regurgitation","Three-dimensional echocardiography","Right ventricular remodeling","2025-03-31",{"date":69,"type":40},"2025-04-06",{"date":71,"type":40},"2024-05-01",{"date":73,"type":21},"2029-02-24",{"name":75,"class":47},"Istituto Auxologico Italiano"]