[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiac-resynchronization-therapy-devices\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiac-resynchronization-therapy-devices":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":32,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100623159","biostreamcsp-study-100623159",false,"NCT07393009","BIO|STREAM.CSP Study","Observation of Clinical Routine Care for Patients Implanted With BIOTRONIK Devices Used for Conduction System Pacing (CSP)","Inclusion Criteria:\n\n* Guideline indication for pacemaker or cardiac resynchronization therapy with or without defibrillation function (CRT-P\u002F-D)\n* Patient is intended for a de novo implantation and LBBAP therapy with an investigational generator and an investigational lead OR has just been implanted with an investigational generator and an investigational lead positioned permanently deep within the intraventricular septum and has not yet been discharged from the hospital OR transitions from the BIO\\|MASTER.CSP study\n* Ability to understand the nature of the study\n* Ability and willingness to perform all follow-up visits\n* Ability and willingness to use the CardioMessenger and acceptance of the BIOTRONIK Home Monitoring concept\n\nExclusion Criteria:\n\n* Planned dation from intended use\n* Planned for cardiac surgical procedures, heart transplantation or interventional measures other than the study procedure within one year after enrollment\n* Life-expectancy less than 12 months\n* Pregnant or breast feeding\n* Age less than 18 years\n* Participation in an interventional clinical investigation, except for submodules within this study.","ALL","18 Years",{"count":19,"type":20},1000,"ESTIMATED","4 Years","OBSERVATIONAL","The registry is designed to assess outcome, performance and residual safety aspects of BIOTRONIK products which are used in the context of CSP based on long-term data from an unselected, real-life clinical set-up.",[25,26,27,28,29,30,31],"Cardiac Pacing","Cardiac Pacemaker","Implantable Cardioverter Defibrillator","Cardiac Resynchronization Therapy Devices","Bradycardia","Tachycardia","Heart Failure",[33,34],"Conduction system pacing (CSP)","Left bundle branch area pacing (LBBAP)","RECRUITING","2026-06-24",{"date":38,"type":39},"2026-06-29","ACTUAL",{"date":41,"type":39},"2026-05-25",{"date":43,"type":20},"2033-02-01",{"name":45,"class":46},"Biotronik SE & Co. KG","INDUSTRY",40,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100640844","comparison-of-the-effects-of-different-upper-extremity-aerobic-exercise-training-protocols-on-arm-functional-capacity-in-patients-with-heart-failure-with-cardiac-implantable-electronic-devices-100640844","NCT07592494","Comparison of the Effects of Different Upper Extremity Aerobic Exercise Training Protocols on Arm Functional Capacity in Patients With Heart Failure With Cardiac Implantable Electronic Devices","Inclusion Criteria:\n\n* Patients aged 18 and over with heart failure who are receiving Implantable Cardioverter Defibrillator (ICD) or Cardiac Resynchronization Therapy (CRT)\n* At least 3 months have passed since device implantation and there have been no complications at the last device control\n* Being in New York Heart Association (NYHA) Class II-III\n* Patients without cooperation problems\n* Patients who volunteer to participate in the study\n\nExclusion Criteria:\n\n* Patients who have previously participated in a cardiac rehabilitation program and those who have completed less than 1 year since the program,\n* Patients with a primary diagnosis of cardiomyopathy and those with heart failure secondary to cardiomyopathy,\n* Patients with a history of shoulder pathologies that may restrict upper extremity movement before device implantation (such as severe pain around the shoulder, edema, or shoulder dislocation that restricts upper extremity movement),\n* Patients with a history of shoulder surgery (patients with limitations in range of motion),\n* Patients who have undergone mastectomy on the affected side or a cerebrovascular event resulting in arm involvement,\n* Patients with decompensated heart failure,\n* Patients with a history of ICD-incompatible shock,\n* Patients with a history of unstable angina pectoris, acute myocardial infarction, or cardiac surgery within the last 3 months,\n* Patients who have experienced acute atrial fibrillation, ventricular tachycardia, and ventricular fibrillation within the last 3 months,\n* Patients with actively treated malignancy or collagen tissue disease receiving systemic steroids\n* Patients with chronic kidney disease undergoing dialysis where volume load is unstable,\n* Persistent ventricular arrhythmias during baseline cardiopulmonary exercise testing.",{"count":55,"type":20},36,"INTERVENTIONAL",[58],"NA","1. To determine the most suitable exercise protocol for upper extremity aerobic exercise training, a widely used type of aerobic exercise to improve reduced upper extremity functional capacity in individuals with CIED and HF.\n2. To investigate whether high-intensity intermittent upper extremity aerobic exercise training provides a more effective improvement in upper extremity functional capacity compared to moderate-intensity continuous upper extremity aerobic exercise training.\n3. To determine the effectiveness of different types of upper extremity aerobic exercise training compared to lower extremity aerobic training alone in individuals with CIED and HF.",[31,61,28],"Implantable Cardioverter Defibrillator (ICD)",[27,63,31,64,65,66],"Cardiac Resynchronization Therapy Device","Upper Extremity Aerobic Exercise","Cardiac Rehabilitation","Physiotherapy and Rehabilitation","NOT_YET_RECRUITING","2026-05-11",{"date":70,"type":39},"2026-05-18",{"date":68,"type":20},{"date":73,"type":20},"2027-05-11",{"name":75,"class":76},"Erol Olcok Corum Training and Research Hospital","OTHER"]