[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiac-surgery-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiac-surgery-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100631111","manual--vs-auto-strain-100631111",false,"NCT07496424","Manual- VS Auto-Strain","Automated Measurements of Left Ventricular Longitudinal Strain: Are the Results Comparable to Manual Measurements During Cardiac Surgery?","Inclusion Criteria:\n\n* Adult (≥18 years) cardiac surgery patients\n* Sinus rhythm\n* No severe valvular regurgitation\n* Use of General Electric (GE) echocardiography systems (Vivid S60, S70, E95) and corresponding EchoPAC software as well as TOMTEC software.\n\nExclusion Criteria:\n\n* Inadequate image quality\n* Any severe heart valve regurgitation\n* Mechanical circulatory support systems (e.g., LVAD, Impella, ECMO)","ALL","18 Years","99 Years",{"count":20,"type":21},70,"ESTIMATED","1 Day","OBSERVATIONAL","Myocardial strain analysis provides additional and valuable information about left ventricular function, particularly in the perioperative setting with its dynamic changes in ventricular load conditions. This allows for earlier risk assessment and, if necessary, the initiation of faster and more targeted therapy. Unfortunately, conventional strain analysis using conventional methods currently takes approximately 5 minutes. However, this amount of time is often not available in a dynamically changing intraoperative setting during cardiac surgery. Therefore, the benefits of strain analysis have not yet been routinely utilized during the intraoperative course. However, new software solutions exist that can perform strain analysis fully automatically and reduce the examination time to a few seconds. However, it remains unclear whether these fully automated analyses also function reliably intraoperatively using transesophageal echocardiography (TEE). The aim of this study is to assess the reliability of these new methods.",[26,27,28],"Transesophageal Echocardiography","Cardiac Anesthesia","Cardiac Surgery Patients","RECRUITING","2026-03-22",{"date":32,"type":33},"2026-03-27","ACTUAL",{"date":35,"type":21},"2026-03-23",{"date":37,"type":21},"2027-03-23",{"name":39,"class":40},"Bruno Mora","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":52,"conditions":53,"keywords":57,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":41},"100616395","study-of-ultrasound-windows-for-measuring-inferior-vena-cava-changes-before-cardiac-surgery-100616395","NCT07305051","Study Of Ultrasound Windows For Measuring Inferior Vena Cava Changes Before Cardiac Surgery","Comparison of Transhepatic and Subcostal Views for Assessing Inferior Vena Cava Diameter Variation in Cardiac Surgery Patients","THRIVE-CARD","Inclusion Criteria:\n\n* Adults aged eighteen years or older\n* Scheduled to undergo cardiac surgery at Sunnybrook Health Sciences Centre\n* Spontaneously breathing at the time of ultrasound assessment\n* Able to lie supine for image acquisition\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Inability to lie supine\n* Known right heart failure\n* Moderate to severe tricuspid regurgitation\n* Portal hypertension\n* End-stage renal disease\n* Presence of abdominal dressings or conditions that preclude transhepatic imaging\n* Poor acoustic windows that prevent adequate measurement from either the subcostal or transhepatic view, despite standard optimization techniques (positioning, breathing coaching, depth and gain adjustment, probe angulation)",{"count":51,"type":21},283,"This research study will compare two ultrasound methods for assessing the inferior vena cava (IVC), a major vein that reflects intravascular fluid status and cardiac function before and after surgery. The standard method uses a subcostal ultrasound view obtained below the breastbone, but this approach may be limited in patients with obesity, surgical dressings, or postoperative discomfort. An alternative approach, the transhepatic view, uses the liver as an acoustic window and may provide improved feasibility in these situations.\n\nThe study will evaluate whether the transhepatic view provides measurements comparable to the standard subcostal view and whether operators with different levels of ultrasound experience obtain consistent results using both methods. Adult patients who are awake and scheduled for cardiac surgery at Sunnybrook Health Sciences Centre will undergo a brief ultrasound examination before surgery. The scan takes less than 10 minutes, involves no discomfort, and does not alter clinical care. This is a minimal-risk observational study with no therapeutic interventions. Participation is voluntary, and all personal health information will remain confidential. Findings may inform future approaches to ultrasound-guided assessment and training in perioperative care.",[54,55,56,28],"Perioperative Fluid Management","Hemodynamic Monitoring","Inferior Vena Cava Collapsibility Index",[58,59,60,61,62,63,64,65,66,67,68,69],"point-of-care ultrasound (POCUS)","Transhepatic view","Subcostal view","Inferior vena cava (IVC)","Echocardiography","Ultrasound imaging","Central venous assessment","Cardiac surgery","Fluid status assessment","Interrater reliability","Sunnybrook Health Sciences Centre","Adult patients","NOT_YET_RECRUITING","2025-12-11",{"date":73,"type":33},"2025-12-26",{"date":75,"type":21},"2026-01",{"date":77,"type":21},"2028-12",{"name":68,"class":40},{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":93,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":41},"100526653","hpi-for-prevention-of-hypotension-during-cardiac-surgery-100526653","NCT06137547","HPI for Prevention of Hypotension During Cardiac Surgery","Hypotension Prediction Index for Prevention of Hypotension During Cardiac Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* adult\n* elective, primary, isolated coronary arterial bypass surgery (CABG) or isolated valve surgery\n* provide inform consent.\n\nExclusion Criteria:\n\n* arrhythmia (e.g., atrial fibrillation, atrial flutter)\n* intracardiac shunts\n* preoperative inotropic usage\n* preoperative supportive devices usage (e.g., intra-aortic balloon pump, extracorporeal membrane oxygenation, left ventricular assist device, or right ventricular assist device)\n* receiving urgent or emergent procedures.",{"count":87,"type":21},110,"INTERVENTIONAL",[90],"NA","Hypotension prediction index (HPI) was applied in various types of non-cardiac surgery with convincing benefits of preventing hypotensive events and clinical sequelae. Although HPI was validated in cardiac surgery, its clinical benefits are not proven yet. We aim to evaluate its effects on intraoperative hypotension and postoperative adverse events in cardiac surgery. In this randomized, single-blind trial, we will enroll adults scheduled for elective primary cardiac surgery under general anesthesia. Participants will be randomly assigned to intraoperative HPI-guided or non-HPI-guided hemodynamic management. The primary endpoint is the time-weighted average intraoperative hypotension below a mean arterial pressure threshold of 65 mmHg. The secondary endpoints are postoperative complications.",[28],[94,95,96,97],"cardiac surgery","hypotension prediction index","hypotension","randomized controlled trial","2025-05-06",{"date":100,"type":33},"2025-05-08",{"date":102,"type":33},"2023-11-20",{"date":104,"type":21},"2027-08-31",{"name":106,"class":40},"Mackay Memorial Hospital"]