[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiopathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiopathy":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":5},"100637842","effectiveness-of-a-structured-multidimensional-tele-rehabilitation-intervention-in-cardiac-patients-with-post-intensive-care-syndrome-cardio-pics-100637842",false,"NCT07599306","Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)","Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS): Impact on Mortality, Rehospitalization, and Clinical-functional Outcomes.","CARDIO-PICS","Inclusion Criteria:\n\n* Adults aged 30-75 years\n* Previous ICU admission ≥48 hours\n* Presence of Post-Intensive Care Syndrome (PICS), defined as at least one of the following objectively assessed impairments at baseline (T0):\n* Neuromotor impairment, defined as Diagnosis of Critical Illness Myopathy (CIM) or Critical Illness Polyneuropathy (CIP), confirmed by electromyography (EMG)\n* Cognitive impairment, defined as Montreal Cognitive Assessment (MoCA) score \\\u003C 26\n* Psychological impairment, defined as Patient Health Questionnaire-9 (PHQ-9) score ≥ 10\n* Nutritional impairment, defined as the presence of malnutrion according to GLIM criteria, requiring at least one phenotypic criterion (non-volitional weight loss \\>5% within 6 months or \\>10% beyond 6 months; BMI \\\u003C20 kg\u002Fm² if \\\u003C70 years or \\\u003C22 kg\u002Fm² if ≥70 years; reduced muscle mass) and at least one etiologic criterion (reduced food intake or assimilation for \\>1 week, or any acute\u002Fchronic inflammatory burden) and\u002For presence of sarcopenia assessed by calf circumference \\\u003C31 cm and reduced muscle strength measured by handgrip strength\n* Metabolic or bone metabolism disorder, defined as altered bone metabolism markers (Bone Turnover Markers outside reference range)\n\nAbility to provide written informed consent\n\nExclusion Criteria\n\n* Prognostically unfavorable malnutrition defined as: CONUT score ≥5.\n* Delirium present at the time of the enrollment, documented by a positive Confusion Assessment Method (CAM or CAM-ICU)\n* Pre-existing severe cognitive impairment or dementia, defined as:\n\ndocumented diagnosis in the medical record prior to ICU admission\n\n\\- Any clinical condition limiting participation in the rehabilitation program, including: severe orthopedic, neurological, or functional limitations not related to PICS","ALL","30 Years","75 Years",{"count":21,"type":22},326,"ESTIMATED","INTERVENTIONAL",[25],"NA","This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS). The post-rehabilitation phase is crucial for consolidating recovery and ensuring continuity of care, with telerehabilitation offering a promising tool to enhance long-term adherence and outcomes.\n\nThe primary objective is to evaluate whether a structured, multidisciplinary remote rehabilitation program can reduce the risk of rehospitalization and mortality while improving clinical, functional, and psychosocial recovery. Approximately 326 patients aged 30-75 years will be enrolled after inpatient rehabilitation and randomly assigned to either a four-month structured telerehabilitation program or standard post-discharge follow-up.\n\nAll participants will undergo assessments at 4 and 12 months to monitor physical, cognitive, psychological, and metabolic recovery, with the ultimate aim of promoting a more complete and sustained rehabilitation after critical illness.",[28,29,30],"Critical Illness","Post Intensive Care Syndrome (PICS)","Cardiopathy",[32,33,34,35,36,37,38,39,40,41],"ICU","PICS","Multimodal rehabilitation","critical illness recovery","Polyneuropathies","Sarcopenia","Nutrition Assessment","Cognitive Dysfunction","Metabolic Diseases","tele-rehabilitation","RECRUITING","2026-06-03",{"date":45,"type":46},"2026-06-04","ACTUAL",{"date":48,"type":46},"2026-04-13",{"date":50,"type":22},"2028-12-31",{"name":52,"class":53},"Fondazione Don Carlo Gnocchi Onlus","OTHER"]