[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiovascular-disease-other\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiovascular-disease-other":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100516323","congenital-heart-disease-physical-activity-lifestyle-study-v2-100516323",false,"NCT06003023","Congenital Heart Disease Physical Activity Lifestyle Study V.2","Establishing Efficacy for the Congenital Heart Disease Physical Activity Lifestyle Intervention","CHD-PALS V2","Inclusion Criteria:\n\n* Between the ages of 15-25 years\n* Diagnosed with moderate or complex structural CHD\n* Actively receiving care from a cardiologist at Nationwide Children's Hospital (NCH) or Ohio State University (OSU)\n\nExclusion Criteria:\n\n* Unable to speak and read proficiently in English\n* Have a diagnosis of a genetic syndrome that impacts multiple organ systems\n* Have cognitive impairments that would interfere with completing study measures\n* Have been engaged in a formal exercise program within the past 6 months,\n* Have participated in the intervention arm of the previous CHD-PAL Study\n* Have undergone open-heart surgery or had a valve replacement in the last 3 months\n* Are unable to complete an exercise stress test using a treadmill\n* Are pregnant\n* Are prohibited to engage in at least moderate levels of physical activity by their cardiologist\n* Engage in \\>30 minutes of moderate-to-vigorous physical activity per day, on average per accelerometer\n* Have contraindications for exercise based on an exercise stress test (e.g., exercise-induced arrhythmias or evidence of cardiac ischemia)","ALL","15 Years","25 Years",{"count":21,"type":22},144,"ESTIMATED","INTERVENTIONAL",[25],"NA","The Congenital Heart Disease Physical Activity Lifestyle Intervention Study (CHD-PALS) V.2 seeks to determine the efficacy of a lifestyle intervention program for adolescents and young adults (AYAs) with congenital heart disease (CHD). This trial was adapted from the original CHD-PAL trial to continue improving cardiovascular outcomes for transition-aged CHD survivors.",[28,29],"Heart Defects, Congenital","Cardiovascular Disease Other",[31,32,33,34],"congenital heart disease","physical activity","adolescents","young adults","RECRUITING","2026-05-28",{"date":38,"type":39},"2026-06-01","ACTUAL",{"date":41,"type":39},"2023-07-18",{"date":43,"type":22},"2027-07-30",{"name":45,"class":46},"Jamie Jackson","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":83},"100613351","a-family-centred-approach-enhancing-cardiovascular-health-in-ugandan-adolescents-and-their-families-100613351","NCT07265453","A Family-centred Approach Enhancing Cardiovascular Health in Ugandan Adolescents and Their Families","A Family Centred Approach to Enhance Lifestyle Change and Behavioural Modification for Prevention of Cardiovascular Diseases Among Adolescents and Their Families in Uganda","FaCe-D","Inclusion Criteria:\n\n* Aged 10 -19 years\n* Household head\u002Fparent has provided consent\u002Fpermission\n* Planning to continue staying in the study village for the next 12 months\n\nExclusion Criteria:\n\n* In a boarding school or planning to join a boarding school\n* Pregnant or lactating\n* Known to have a chronic condition such as mental illness\n* The adolescent does not assent or consent",true,"10 Years","19 Years",{"count":60,"type":22},1280,[25],"The FaCe-D Study, with funding from the Canadian Institute for Health Research (CIHR) through Global Alliance for Chronic Diseases (GACD) aims to adapt and implement an evidence-based family centred approach (FCA) to prevent cardiovascular diseases (CVD) among adolescents and their families. This 5-year implementation science study will be conducted in 16 villages in Jinja district and another 16 in Kampala beginning April 2024 to evaluate the effectiveness of FCA in reducing the risk of CVD in Uganda and to assess feasibility, adoption, while measuring the costs of implementation. The study will be implemented by a group of researchers from MRC\u002FUVRI \\& LSHTM, University of British Columbia (Canada), TASO (Uganda) and University of California San Francisco (UCSF) - USA with guidance from the Ministry of Health - Uganda.",[64,65,29],"Adolescent Behavior","Lifestyle Modification",[67,68,69,70,71,72,73],"cardiovascular risk","CVD","Ideal cardiovascular health","physical activity diary","food diary","diet diary","family centered","2025-12-04",{"date":76,"type":39},"2025-12-12",{"date":78,"type":39},"2025-07-05",{"date":80,"type":22},"2028-01",{"name":82,"class":46},"MRC\u002FUVRI and LSHTM Uganda Research Unit",2,{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":56,"sex":17,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":95,"phases":4,"briefSummary":96,"conditions":97,"keywords":101,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":5},"100541756","cardiometabolic-function-in-offspring-mother-and-placenta-after-assisted-reproductive-technology-100541756","NCT06334003","Cardiometabolic Function in Offspring, Mother and Placenta After Assisted Reproductive Technology","COMPART","Inclusion Criteria:\n\nPregnant women who have either had fertility treatment at Rigshospitalet or Herlev Hospital (FET and fresh ET groups) or are scheduled for prenatal ultrasounds at Rigshospitalet or Herlev Hospital (NC group) will be screened for eligibility. Inclusion must happen before their routine ultrasound scan in 1. trimester.\n\nExclusion Criteria:\n\n* Maternal pregestational diabetes type 1 or 2\n* Non-singleton pregnancies\n* Maternal pregestational BMI \\> 35 kg\u002Fm2\n* Severe maternal co-morbidity\n* Oocyte donation","18 Years","40 Years",{"count":94,"type":22},600,"OBSERVATIONAL","The overall objective is to establish the first-of-its-kind longitudinal cohort of pregnant women, biological fathers\u002Fpartners and offspring from pregnancies achieved by frozen embryo transfer (FET), fresh-embryo transfer (fresh ET) and naturally conceived (NC) to investigate maternal cardiometabolic profiles, fetal growth patterns and placental function during pregnancy as well as metabolic and endocrine health in the offspring. Additionally, the aim is to explore genetic and epigenetic patterns in placenta, fetus and parents. As secondary objectives, the investigator group will examine telomere length and minipuberty hormones in children born after FET, fresh-ET and NC.",[98,99,100,29],"ART","IVF","Children, Only",[102,103,104,99],"Frozen embryo transfer","Cardiovascular","Metabolic","2024-11-20",{"date":107,"type":39},"2024-11-25",{"date":109,"type":39},"2024-05-17",{"date":111,"type":22},"2027-01-01",{"name":113,"class":46},"Rigshospitalet, Denmark"]