[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiovascular-surgical-procedures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiovascular-surgical-procedures":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,74,100],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100573953","the-effect-of-eye-mask-and-earplugs-on-sleep-quality-and-delirium-in-coronary-artery-bypass-graft-patients-a-randomized-controlled-study-100573953",false,"NCT06752980","The Effect of Eye Mask and Earplugs on Sleep Quality and Delirium in Coronary Artery Bypass Graft Patients: A Randomized Controlled Study","Inclusion Criteria:\n\n-Patients who voluntarily agree to participate in the study\n\n* Those who have undergone coronary artery bypass graft surgery\n* Those between the ages of 18-79\n* Those who are cooperative and oriented\n* Those who are literate\n* Those who speak Turkish\n* Those whose initial delirium scale score (Nu-DECS) is less than 2\n* Those whose Glasgow coma scale score is \\>13 will be included in the study.\n\nExclusion Criteria:\n\n* • Patients diagnosed with sleep disorders,\n\n  * Those using sleeping pills,\n  * Those who have a habit of using an eye patch while sleeping,\n  * Those who were not transferred to the clinic on the first day after surgery and whose treatment continues in the intensive care unit,\n  * Those who develop complications and\u002For need to be re-operated,\n  * Those who need treatment other than routine treatment,\n  * Patients with hearing or vision problems will be excluded.","ALL","18 Years","79 Years",{"count":19,"type":20},128,"ESTIMATED","INTERVENTIONAL",[23],"NA","Coronary artery bypass grafting is the most commonly performed surgical procedure among cardiovascular diseases. Nursing care for patients undergoing cardiac surgery involves a process that includes preoperative preparation and subsequent close monitoring of neurological, cardiac, respiratory, vascular status, kidney function, and pain. Sleep disturbances are observed after cardiac surgery. Sleep plays a critical role in the body's maintenance, repair, and renewal processes. Improved sleep can reduce patient agitation and decrease the risk of delirium. The presence of delirium leads to increased care requirements and prolonged hospital stays, which in turn raises hospital costs. Enhancing sleep quality and preventing delirium after surgery have positive effects on clinical patient outcomes. This study is designed to determine the effects of using eye masks and\u002For earplugs on sleep quality and delirium in patients undergoing coronary artery bypass grafting during nighttime sleep. This research is a randomized controlled clinical trial.",[26],"Cardiovascular Surgical Procedures",[28],"Cardiovascular surgical procedures, Delirium, Sleep","NOT_YET_RECRUITING","2026-06-15",{"date":32,"type":33},"2026-06-17","ACTUAL",{"date":35,"type":20},"2026-09-07",{"date":37,"type":20},"2026-11-01",{"name":39,"class":40},"Necmettin Erbakan University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":49,"enrollmentInfo":50,"targetDuration":52,"studyType":53,"phases":4,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":41},"100635778","fascial-plane-blocks-and-quality-of-recovery-in-cardiac-surgery-100635778","NCT07557108","Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery","Pecto-Intercostal Fascial Plane Block-Based Multimodal Analgesia to Improve Quality of Recovery After Median Sternotomy: A Randomized Non-Inferiority Trial Comparing Retro-Intercostal Fascial Plane Block and Rectus Sheath Block","Inclusion Criteria:\n\n* Patients who have provided written informed consent\n* Open-heart surgery performed under elective conditions via median sternotomy with cardiopulmonary bypass (on-pump)\n* American Society of Anesthesiologists (ASA) physical status class II or III\n* Aged 18-70 years\n\nExclusion Criteria:\n\n* Off-pump surgical procedure\n* Emergency or repeat cardiac surgery\n* Known allergy to induction agents or local anesthetics\n* Body mass index (BMI) \\>35 kg\u002Fm²\n* Coagulopathy\n* Infection at the surgical site\n* Left ventricular ejection fraction (LVEF) \\\u003C40%\n* Renal insufficiency (estimated glomerular filtration rate \\\u003C60 mL\u002Fmin\u002F1.73 m²) or hepatic insufficiency \\[Presence of major systemic diseases such as acute decompensated cirrhosis characterized by bilirubin \\>12 mg\u002FdL, INR \\>2.5, or hepatic encephalopathy, in accordance with the European Association for the Study of the Liver-Chronic Liver Failure Consortium criteria\\]\n* Psychiatric disorders\n* History of chronic pain or regular use of analgesics (corticosteroids, analgesics, anticonvulsants)\n* Cognitive impairments that could interfere with the assessment of postoperative pain\n* Patients with impaired physical and verbal performance","70 Years",{"count":51,"type":20},123,"1 Year","OBSERVATIONAL","In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB will accelerate recovery. Additionally, it is anticipated that RIFB, an alternative fascial plane block, will demonstrate non-inferior (at least as effective as) performance compared to RSB, thereby providing flexibility and ease of application in clinical practice.",[26,56,57],"Pain, Postoperative","Cardiovascular Diseases",[26,59,60,61,62,63],"Anesthesia, Conduction","Acute Postoperative Pain","Pain Management","Enhanced Recovery After Surgery","Anesthesia, Regional","RECRUITING","2026-04-28",{"date":67,"type":33},"2026-05-04",{"date":69,"type":33},"2026-04-05",{"date":71,"type":20},"2026-12-20",{"name":73,"class":40},"Ordu University",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":82,"targetDuration":84,"studyType":53,"phases":4,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":41},"100622650","propofol-infusion-and-ponv-in-cardiac-surgery-100622650","NCT07386379","Propofol Infusion and PONV in Cardiac Surgery","The Effect of Propofol Infusion on Postoperative Nausea and Vomiting in Cardiac Surgery: A Prospective Observational Cohort Study","nausea vomitng","Inclusion Criteria\n\nAge ≥ 18 years\n\nASA physical status III\n\nElective coronary artery bypass grafting (CABG)\n\nSurgery performed at Istanbul University-Cerrahpaşa, Cardiology Institute between November 2025 and March 2026\n\nExclusion Criteria\n\nGastrointestinal or central nervous system disorders within the past 3 months\n\nCochlear disorders associated with nausea and vomiting\n\nChronic opioid use\n\nAdvanced hepatic or renal disease\n\nAlcohol or substance abuse\n\nLeft ventricular ejection fraction \\\u003C 40%\n\nInability to be weaned from mechanical ventilation within 12 hours postoperatively\n\nPostoperative morphine administration in the intensive care unit\n\nCombined cardiac procedures (e.g., valve surgery)\n\nOff-pump surgery\n\nEmergency surgery\n\nReoperation due to bleeding or other complications\n\nRefusal to participate",{"count":83,"type":20},60,"1 Day","The aim of this observational cohort study is to evaluate the effect of high-dose versus low-dose propofol infusion on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing coronary artery bypass grafting (CABG). The study also seeks to assess the predictive performance of the Apfel and Koivuranta risk scores for PONV in the cardiac surgery population.\n\nThe primary objective of this study is to determine the impact of routinely administered high-dose propofol on the incidence and severity of PONV in CABG patients.\n\nThe secondary objective is to evaluate the need for antiemetic therapy during the intensive care unit stay.\n\nThe investigators will compare patients receiving high-dose propofol with those receiving low-dose propofol to determine whether the antiemetic effect of propofol is dose-dependent.\n\nParticipants will be asked to:\n\nAllow PONV assessments to be performed during the first 24 hours postoperatively,\n\nProvide permission for the collection of clinical data (including demographic characteristics, risk scores, opioid consumption, etc.) for research purposes.",[87,26],"Postoperative Nausea and Vomiting",[87,89,90,26],"Propofol","Cardiac Surgical Procedures","2026-02-03",{"date":93,"type":33},"2026-02-04",{"date":95,"type":33},"2025-11-01",{"date":97,"type":20},"2026-04-30",{"name":99,"class":40},"Istanbul University - Cerrahpasa",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":128},"100619723","vitamin-b-supplementation-for-patients-undergoing-cardiovascular-surgery-100619723","NCT07348328","Vitamin B Supplementation for Patients Undergoing Cardiovascular Surgery","Vitamin B Supplementation for Patients Undergoing Cardiovascular Surgery: A Randomized Controlled Trial","PANDA XII","Inclusion Criteria:\n\n* Aged 18-80 years, regardless of gender;\n* Scheduled to receive cardiovascular surgery at the research center, including coronary artery bypass grafting (CABG), cardiac valve replacement\u002Frepair, and great vessel surgery;\n* Preoperative assessment indicates that the patient is expected to complete the 6-month postoperative follow-up;\n* The patient or their authorized agent signs a written informed consent form.\n\nExclusion Criteria:\n\n* Regular supplementation with Compound Vitamin B (daily dose ≥ 1.5 times the recommended dietary allowance) or separate supplementation with folic acid, vitamin B6, or B12 within 3 months before surgery;\n* Severe hepatic or renal insufficiency (liver function: ALT\u002FAST \\> 3 times the upper limit of normal, or total bilirubin \\> 2 times the upper limit of normal; renal function: serum creatinine \\> 265 μmol\u002FL, or requiring long-term dialysis treatment);\n* Malignant tumors, severe hematological diseases (e.g., megaloblastic anemia, aplastic anemia), severe malnutrition (albumin \\\u003C 25 g\u002FL);\n* History of allergy to Compound Vitamin B preparations or placebo components; Pregnant women, lactating women, or those planning to become pregnant during the study period;\n* Currently participating in other interventional clinical trials;\n* Moderate to severe cognitive impairment without a fixed caregiver, unable to cooperate with treatment and follow-up;\n* Preoperatively diagnosed with severe infection, septicemia, or septic shock.","80 Years",{"count":110,"type":20},1000,[23],"This study is a multicenter, randomized controlled, double-blind, placebo-controlled parallel trial designed to evaluate the effect of perioperative supplementation with Compound Vitamin B on patients undergoing cardiovascular surgery. A total of 1,000 patients aged 18-80 years who are scheduled to receive cardiovascular surgeries such as coronary artery bypass grafting (CABG) and valve replacement will be enrolled. They will be randomly assigned at a 1:1 ratio to either the experimental group (perioperative supplementation with Compound Vitamin B tablets, once daily from 3 days before surgery to 6 months after surgery) or the control group (oral placebo), with both groups receiving standardized perioperative treatment.",[26,114],"Major Adverse Cardiovascular Events (MACE)",[116,117,118],"Compound Vitamin B","Cardiovascular Surgery","Major Adverse Cardiovascular Events","2026-01-09",{"date":121,"type":33},"2026-01-16",{"date":123,"type":20},"2026-02-01",{"date":125,"type":20},"2027-12-31",{"name":127,"class":40},"Nanjing Medical University",2]