[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiovascular-system\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiovascular-system":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100631533","the-effects-of-daytime-nighttime-and-combined-heat-exposure-on-human-health-100631533",false,"NCT07501923","The Effects of Daytime, Nighttime, and Combined Heat Exposure on Human Health","Randomized Controlled Crossover Trial on the Effects of Daytime, Nighttime, and Combined Heat Exposure on Human Health","Inclusion Criteria:\n\n* Age 18-30;\n* In good health, with no history of cardiovascular disease, respiratory disease, diabetes, endocrine disorders, neurological or psychiatric conditions;\n* No smoking or alcohol addiction, no history of substance abuse;\n* No prior history of particular sensitivity to high-temperature environments.\n\nExclusion Criteria:\n\n* Individuals who have experienced fever, colds, infectious diseases, or significant physical trauma within two weeks prior to the high-temperature test;\n* Individuals currently using medications that may affect psychological, cognitive, cardiovascular, or respiratory functions;\n* Pregnant women and lactating females;\n* Participants shall not be scheduled to participate during menstruation;\n* Individuals with a history of fainting or severe discomfort caused by high temperatures.",true,"ALL","18 Years","30 Years",{"count":21,"type":22},35,"ESTIMATED","INTERVENTIONAL",[25],"NA","Assess the acute effects of high-temperature exposure (including both daytime and nighttime conditions) on multiple physiological and psychological indicators, including cardiovascular, respiratory, neuropsychiatric, and metabolic functions, along with their potential mechanisms.",[28,29,30,31],"Metabolism Changes","Psychology Functional Behavior","Cardiovascular System","Respiratory System","RECRUITING","2026-03-24",{"date":35,"type":36},"2026-03-30","ACTUAL",{"date":38,"type":36},"2025-06-01",{"date":40,"type":22},"2026-12-31",{"name":42,"class":43},"Jian Cheng","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":67,"locationsCount":44},"100566226","acute-effects-of-cold-exposure-on-cardiovascular-system-100566226","NCT06652425","Acute Effects of Cold Exposure on Cardiovascular System","Acute Effects of Cold Exposure on Cardiovascular System and Potential Mechanism in Healthy Young Adults: A Randomized Controlled Study","Inclusion Criteria:\n\n* Living in Shanghai during the study period;\n* Body mass index \\> 18.5 and ≤ 28;\n* Right-handed;\n* Receiving or having received higher education;\n* With the ability to read and understand Chinese smoothly.\n\nExclusion Criteria:\n\n* Smoking and alcohol abuse;\n* Current drug and dietary supplements intake;\n* Subjects with allergic diseases, such as allergic rhinitis, allergic asthma, and atopy;\n* Subjects with cardiovascular diseases, such as congenital heart disease, pulmonary heart disease, and hypertension;\n* Subjects with respiratory diseases, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease;\n* Subjects with chronic diseases, such as diabetes, chronic hepatitis, and kidney disease;\n* Subjects who have a history of major surgery due to cardiovascular, cerebrovascular, respiratory, or neurological diseases;\n* Subjects with neurologic disorders, such as stroke, traumatic brain injury, epilepsy, and schizophrenia;\n* Abnormal spirometry (FEV1 and FVC ≤ 75% of predicted and FEV1\u002FFVC ≤ 0.65);\n* Subjects with color vision disabilities.",{"count":53,"type":22},40,[25],"This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.",[30],[58,59,60],"Low temperature","Randomized controlled trial","Cardiovascular system","2025-02-25",{"date":63,"type":36},"2025-02-27",{"date":65,"type":36},"2024-10-16",{"date":40,"type":22},{"name":68,"class":43},"Fudan University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":4,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":44},"100567060","acute-effects-of-meteorological-factors-and-air-pollution-on-cardiovascular-health-100567060","NCT06663267","Acute Effects of Meteorological Factors and Air Pollution on Cardiovascular Health","Inclusion Criteria:\n\n·Relevant records in the physical examination database shall be ≥3 times\n\n·≥18 years old\n\nExclusion Criteria:\n\n* Relevant records in the physical examination database shall be ≥３times\n* Serious heart and lung diseases\n* Malignant tumors\n* Serious mental illness in the past","75 Years",{"count":77,"type":22},350000,"OBSERVATIONAL","The goal of this observational study is to analyze the acute effects of meteorological factors and air pollution on cardiovascular system. The main question it aims to answer is:\n\n1. How do meteorological factors and air pollution affect cardiovascular system?\n2. What is the interaction between meteorological factors and air pollution on cardiovascular system?\n\nParticipants will:\n\n1. Provide their health data obtained in physical examination, including but not limited to blood pressure, blood routine, urine routine and B-ultrasound.\n2. agree that the research team will use their personal identification number, gender, age, education level and other information for statistical analysis of the data.",[30,81],"Health",[30,83,84,85],"Air Pollution Exposure","Acute effect","Weather","2024-10-26",{"date":88,"type":36},"2024-10-29",{"date":90,"type":22},"2024-11",{"date":92,"type":22},"2028-05",{"name":94,"class":43},"The Affiliated Hospital of Hangzhou Normal University"]