[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"caregiver-burden-of-people-with-dementia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:caregiver-burden-of-people-with-dementia":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,44,75,97,117],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100628402","penn-state-emergency-medicine-cares-care-partner-evaluation-and-sourcing-in-the-emergency-department-100628402",false,"NCT07461168","Penn State Emergency Medicine CarES: Care-partner Evaluation and Sourcing in the Emergency Department","Penn State Emergency Medicine CarES: Care-partner Evaluation and Sourcing in the ED","CarES","Inclusion Criteria:\n\n* Person completed the CarES Observational Study.\n* Person is a care partner and:\n* Lives with the person living with dementia or\n* Checks on them at least once per week in person or by phone\n* Person is willing and able to participate in study assessments\n\nExclusion Criteria:\n\n* Person is no longer a care partner for a person living with dementia\n* Person declines participation","ALL","60 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","Care partners of people living with dementia often experience ongoing stress and unmet support needs. This study evaluates the feasibility of a low-intensity, supportive education and resource intervention for care partners who previously participated in an observational study.\n\nParticipants complete a baseline phone interview and a short stress journaling activity, followed by a six-week series of automated educational and supportive messages delivered by text message or email. Participants may also take part in an optional peer support focus group. The study examines caregiver stress, resilience, engagement with resources, and participant feedback to inform future caregiver support interventions.",[27,28,29,30],"Dementia","Caregiver Stress","Caregiver Burden","Caregiver Burden of People With Dementia","NOT_YET_RECRUITING","2026-06-12",{"date":34,"type":35},"2026-06-15","ACTUAL",{"date":37,"type":21},"2026-07-01",{"date":39,"type":21},"2026-12-30",{"name":41,"class":42},"Milton S. Hershey Medical Center","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":43},"100612156","feasibility-of-wearables-in-dementia-care-in-rural-taiwan-100612156","NCT07249918","Feasibility of Wearables in Dementia Care in Rural Taiwan","Facilitating the Measurement and Treatment of the Behavioral Symptoms of Dementia (BPSD) and Understanding Caregiver Burden Using Wearable Devices in Rural Taiwan - A Dyadic Feasibility Pilot Study","Inclusion Criteria:\n\n* For participants with dementia:\n\n  1. Clinical diagnosis of probable Alzheimer's disease (AD) or mild cognitive impairment (MCI) due to AD, based on established diagnostic criteria.\n  2. Presence of at least one prominent behavioral or psychological symptom of dementia (BPSD), including depression, agitation, apathy, or nighttime sleep disturbance.\n  3. Prominent is defined as:\n\n     NPI single-item score ≥ 4 (severity × frequency), or NPI-Q severity score ≥ 2, or PSQI total score ≥ 5 (if sleep disturbance is the main symptom).\n  4. Stable living arrangement or care environment for at least two weeks before enrollment.\n  5. If receiving any pharmacological or non-pharmacological treatments for BPSD, the dosage and frequency must have remained stable for at least two weeks prior to study participation.\n  6. Able and willing to provide informed consent; for those lacking decision-making capacity, consent must be obtained from a legally authorized representative.\n* For primary caregivers:\n\n  1. Adult primary caregiver of the enrolled participant.\n  2. If receiving treatment for caregiver stress, the dosage and frequency must have been stable for at least two weeks before enrollment.\n  3. Willing and able to provide informed consent.\n\nExclusion Criteria:\n\n* Any medical condition that may increase risk during participation, including:\n\n  1. Retinal disease, active use of photosensitizing medications, recent ocular surgery (within 4 weeks), or photosensitivity disorders (e.g., epilepsy).\n  2. Unstable physical or mental condition deemed unsuitable by investigators, such as acute delirium or active respiratory infection (including COVID-19)",true,{"count":20,"type":21},[24],"Taiwan is becoming a super-aged society, and more older adults are living with Alzheimer's disease. Many people with Alzheimer's experience behavioral and psychological symptoms, such as agitation, sleep problems, or mood changes. These symptoms often lower their quality of life and increase stress for their family caregivers.\n\nThis study will test two wearable devices in people with Alzheimer's and their caregivers. One device, called Geneactiv, is a wristwatch that tracks daily activity and sleep. The other device, called Re-Timer, is a light therapy eyewear that may help improve sleep and mood. Researchers will look at how easy the devices are to use, whether participants are willing to wear them for several weeks, and whether the light therapy helps reduce sleep problems or caregiver stress.\n\nThe study will also compare information from questionnaires with information collected by the devices. The results may help researchers design future studies using wearable tools to better support people living with dementia and their caregivers.",[56,57,58,30,59],"Alzheimer's Dementia","Neuropsychiatric Symptoms Related to Neurodegenerative Disease","Wearable Devices","Circadian Rhythm",[61,62,63,64,29],"Wearable device","behavioural and psychological symptoms of dementia (BPSD)","Sleep","Alzheimer's dementia","RECRUITING","2026-02-09",{"date":68,"type":35},"2026-02-11",{"date":70,"type":35},"2025-11-18",{"date":72,"type":21},"2026-12-31",{"name":74,"class":42},"China Medical University Hospital",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":51,"sex":17,"minAge":83,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":95,"locationsCount":4},"100600895","vr-based-mindfulness-for-dementia-caregivers-in-the-home-environment-mind-body-interventions-100600895","NCT07103434","VR-based Mindfulness for Dementia Caregivers in the Home Environment (Mind-body Interventions)","A Feasibility Study on the Efficacy of a VR-based Mindfulness Intervention for Dementia Caregivers in the Home Environment: A Pilot Randomized Control Trial","vrmdc","Inclusion Criteria:\n\n* Aged 18 years or older;\n* Primary informal caregivers who spend over four hours\u002Fday taking care of a community-dwelling person who has been clinically diagnosed with any type of mild-to-moderate dementia at least 6 months;\n* Self-reported psychological distress\n* Able to speak and read Cantonese.\n\nExclusion Criteria:\n\nHave practiced mindfulness-based intervention for at least 3 months in the past;\n\n* Have hearing or visual impairment that cannot practice mindfulness via wearing VR\n* glasses embedded in a mobile phone app;\n\n  --Do not own a smart phone that can install the VR-based MBI app;\n* Caring for a person with dementia living in a residential care setting;\n* Caring a person with severe level of dementia;\n* Have been diagnosed with any mental disorder or on-site of psychotic disorders;\n* Receiving any other type of mental health intervention;\n* Participants with a history of motion sickness (due to the risk of VR triggering motion sickness)\n* Unable to understand Cantonese.\n\nsickness)\n\n-Unable to understand Cantonese.","18 Years",{"count":85,"type":21},90,[24],"To explore the feasibility, acceptability, and potential effectiveness among dementia caregivers of the mindfulness-based interventions delivered by VR technology (VR-based MBI) in improving psychological well-being and caregiver-recipient relationship.\n\nThis study hypothesized that caregivers in the VR-based MBI group will have a greater improvement in psychological wellbeing than those in the audio-based MBI group and the waitlist care-as-usual group.\n\nThis is a 3-arm, parallel, single-blinded, pilot randomised control trial comparing VR-based MBI with audio-based MBI and care-as-usual. The target sample includes 90 caregivers of community-dwelling persons with dementia. Each arm (n=30) will receive an eight-week exercise with instruction, with outcome assessment at baseline, post-treatment,\n\nand 2-month follow-up. Qualitative interviews will also be conducted to assess the feasibility and acceptance. The VR-based MBI group will engage in mindfulness exercises using a mobile app and VR technology, incorporating different natural environments. The intervention duration is eight weeks. The primary outcome is the caregivers' psychological well-being regarding depression, anxiety, and stress. The secondary outcomes include caregiver burden, mindfulness level, quality of life and caregiver-recipient relationship.\n\nFollowing intention-to-treat analysis, quantitative data on effectiveness will be analysed using between-group t-tests and group-by-time effect size (Cohen's d). The six-step thematic analysis will be utilized for qualitative data. The intervention group will accept the VR-based MBI, rate the intervention as feasible and show significant improvements in outcome measurements.",[27,30],"2025-08-02",{"date":91,"type":35},"2025-08-05",{"date":93,"type":21},"2025-08-01",{"date":72,"type":21},{"name":96,"class":42},"The University of Hong Kong",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":4,"enrollmentInfo":105,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":115,"locationsCount":43},"100600397","implementation-of-the-start-intervention-in-brazil-a-controlled-feasibility-trial-100600397","NCT07096960","Implementation of the START Intervention in Brazil: a Controlled Feasibility Trial","A Brazilian Version of the STrAtegies for RelaTives (START) Intervention in the Unified Health System (SUS): a Controlled Feasibility Trial","START\u002FESCADA","Inclusion Criteria:\n\n* Informal caregivers (≥18 years old) who are the primary or one of the primary persons responsible for caring for a family member with dementia, providing regular and sustained emotional or practical support every week, and living in the same household or nearby with frequent face-to-face interaction.\n* Care recipient (person with dementia) with Clinical Dementia Rating (CDR) score ≥1.\n* Care recipient with at least one ICD-10 dementia diagnosis code documented in their medical record.\n\nExclusion criteria:\n\n* Illiterate caregivers.\n* Caregivers who provide only occasional or sporadic support (less than weekly or without regular caregiving responsibility).\n* Care recipients who are institutionalized (e.g., living in long-term care facilities).",{"count":85,"type":21},[24],"This controlled trial aims to assess the feasibility of a culturally adapted Brazilian version of the START (STrAtegies for RelaTives) program, a structured coping strategy program designed for family caregivers of people living with dementia. The program will be delivered by trained community general health workers (CGHW) in 10 municipalities across Brazil. Outcomes will include measures of feasibility and acceptability, as well as caregiver burden, mental health, and quality of life, assessed at baseline and after 6 months.",[30],"2025-07-29",{"date":111,"type":35},"2025-07-31",{"date":113,"type":35},"2025-07-01",{"date":72,"type":21},{"name":116,"class":42},"Hospital Alemão Oswaldo Cruz",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":51,"sex":17,"minAge":83,"maxAge":124,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":127,"briefSummary":128,"conditions":129,"keywords":130,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":43},"100573542","demonstrating-the-efficacy-of-a-spanish-language-program-for-latino-dementia-caregivers-100573542","NCT06747637","Demonstrating the Efficacy of a Spanish-Language Program for Latino Dementia Caregivers","Demonstrating the Efficacy of \"Unidos en el Cuidado\" (United in Caring): A Spanish-Language Program for Latino Caregivers of Persons Living With Dementia","Inclusion Criteria:\n\n* identifies with being Hispanic or Latino descent\n* speaks and reads Spanish\n* dementia family caregivers living (or recently lived) in California or whose care recipient lives (or recently lived) in California\n* who identify as women, men, or non-binary,\n* age 18 years or older\n\nExclusion Criteria:\n\n* Severe sensory or physical conditions that interfere with ongoing participation.","100 Years",{"count":126,"type":21},225,[24],"The investigators will test the efficacy of Unidos en el Cuidado® (United in Caring, herein Unidos), a 3-session, culturally-adapted, group psychoeducational and skill-building intervention for 226 Spanish-speaking family caregivers in California.",[30],[131],"wait list control interventional study","2025-06-03",{"date":134,"type":35},"2025-06-06",{"date":136,"type":21},"2025-06-04",{"date":138,"type":21},"2028-06-30",{"name":140,"class":42},"University of Southern California"]