[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"caries-active\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:caries-active":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,43,70,94,122],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100619393","bioceramic-putty-versus-mta-in-pulpotomized-primary-teeth-to-be-covered-with-3d-printed-resin-crowns-versus-stainless-steel-crown-100619393",false,"NCT07344038","Bioceramic Putty Versus MTA in Pulpotomized Primary Teeth to be Covered With 3D Printed Resin Crowns Versus Stainless Steel Crown","Effectiveness of Bioceramic Calcium Silicate-based Pulpotomy Medicament on Primary Molars Restored With 3d Printed Resin Crowns (a Randomized Controlled Clinical Trial)","Inclusion Criteria:\n\n* Children aged from 5 to 7 years. 2. Medically healthy children (ASA I) (Appendix I) 3. Positive or definitely positive behavior (Frankl's rating scale scores III or IV) (Appendix II) 4. Parents\u002Flegal guardians who provide written informed consent Tooth inclusion criteria(8, 14, 31)\n\n  1. Deep carious second primary molars with:\n\n     1. Vital pulp confirmed by absence of clinical and\u002For radiographic signs of necorosis or infection.\n     2. Signs of reversible pulpitis. 10\n  2. Require full coverage restorations\n  3. Cooperative children (Frankl 3 or 4 behavior rating scale)\n\nExclusion Criteria:\n\n* History of spontaneous pain. 2. Tooth mobility. 3. Excessive bleeding from radicular stumps after coronal pulp amputation. 4. Radiographic evidence of pathological root resorption, inter-radicular bone loss, periapical pathology, or canal calcifications. 5. Previous dental treatment of the involved molar. 6. Children with special healthcare needs.","ALL","5 Years","7 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","children aged 5 to 7 years with deep carious second primary molars that require vital pulp therapy will be treated using either MTA or bioceramic putty, then will be fully covered using either stainless steel crowns or 3D printed resin crowns.",[27],"Caries Active",[29],"MTA, bioceramic putty, 3D printed resin crowns, stainless steel crowns","RECRUITING","2026-01-14",{"date":33,"type":34},"2026-01-15","ACTUAL",{"date":36,"type":21},"2026-01-20",{"date":38,"type":21},"2027-04-15",{"name":40,"class":41},"Alexandria University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":42},"100619422","anxiety-during-caries-removal-using-chemo-mechanical-versus-conventional-methods-100619422","NCT07344415","Anxiety During Caries Removal Using Chemo-mechanical Versus Conventional Methods","Level of Anxiety During Caries Removal Using a New Chemo-mechanical Caries Removal System Versus Conventional Drilling Method: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Open carious lesions with dentin involvement, but not involving the pulp in lower molars.\n2. The access of the carious lesion has to be large enough to allow the penetration of the excavator.\n3. Asymptomatic vital teeth, without clinical evidence of pulp, furcation, or periapical pathology.\n4. Patients who sign informed consent.\n5. Co-operative patients approving to participate in the trial.\n\nExclusion Criteria:\n\n1. Patients with spontaneous or elicited pain from caries.\n2. Patients with systemic diseases.\n3. Presence of intraoral\u002Fextraoral swellings.\n4. Deep dental caries involving pulp.\n5. Presence of swelling\u002Ffistula in relation to carious tooth.\n6. Inability to return for recall visits.\n7. Patients with bad oral hygiene\n8. Refuse to participate in the study.","10 Years","25 Years",{"count":53,"type":21},80,[24],"This study aims to clinically assess this newly introduced Egyptian chemo-mechanical caries removal gel versus conventional drilling method . The concept of preserving healthy tooth structures and employing atraumatic restorative techniques during cavity preparation aligns with the principles of minimally invasive dentistry. This approach prioritizes patient comfort, reassurance, and fosters a positive perception of dental treatment.",[27],[58,59,60],"Chemo-mechanical","Rotary","Anxiety","NOT_YET_RECRUITING","2026-01-08",{"date":33,"type":34},{"date":65,"type":21},"2025-12-31",{"date":67,"type":21},"2026-01-31",{"name":69,"class":41},"Cairo University",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":16,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":42},"100586903","the-effect-of-monk-fruit-and-splenda-on-salivary-ph-and-streptococcus-mutans-count-in-vivo-study-100586903","NCT06921434","the Effect of Monk Fruit and Splenda on Salivary Ph and Streptococcus Mutans Count in Vivo Study","Comparative Evaluation of Monk Fruit and Splenda on Salivary ph and Streptococcus Mutans Growth (an in Vivo Study)","Inclusion Criteria:\n\nparticipants aged (20-24) years.\n\n* No active carious lesions or oral diseases.\n* Generally healthy individuals without systemic illnesses.\n* No prior use of preventive dental treatments\n\nExclusion Criteria:\n\n* Participants currently undergoing dental treatment.\n* Those taking medications that alter saliva flow.\n* Presence of painful oral conditions or systemic diseases. Participants have active caries",true,"20 Years","24 Years",{"count":81,"type":21},90,[24],"This study aims to evaluate the changes in salivary pH and Streptococcus mutans count by preparing a solution containing these sweeteners dissolved in distilled water and administering it to the participants. Saliva samples will be collected before using the mouth rinse, and salivary pH will be measured using a pH meter, while S. mutans count will be analyzed in the laboratory.\n\nAfter consuming the solution, salivary pH will be assessed at 1 minute, 15 minutes, and 30 minutes, while the growth of S. mutans will be examined 30 minutes post-rinse.",[27],"2025-09-23",{"date":87,"type":34},"2025-09-24",{"date":89,"type":21},"2025-10-01",{"date":91,"type":21},"2025-12-01",{"name":93,"class":41},"Al-Mustansiriyah University",{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":77,"sex":16,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":4,"studyType":22,"phases":105,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":4},"100602187","clinical-effectiveness-of-bioactive-silica-based-with-calcium-toothpaste-100602187","NCT07120243","Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste","Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste, Sodium Fluoride Varnish in Management of White Spot Lesions (A 6m Randomized Clinical Trial).","Inclusion Criteria:\n\n* Patient with non cavitated carious WSL in at least one upper or lower tooth.\n* Teeth with active non cavitated white spot carious lesions on the cervical one third of the facial or lingual surfaces.\n\nTeeth with initial carious lesions with score 1 or 2 according to The International Caries Detection and Assessment System (ICDAS).\n\n• Teeth with Diagnodent values between 14-20 that refers to early enamel caries.\n\nExclusion Criteria:\n\nPatients with known allergies or adverse reactions to any ingredient of the tested materials.\n\n• Systematic disease and\u002F or physical disabilities that may affect participation.\n\n• Patients with white spots due to congenital reasons e.g. enamel hypomineralization.\n\n• Pregnant females with frequent vomiting attacks.\n\n• Smokers.\n\n• Excessive dietary or environmental exposure to acids.\n\n* Presence of surface cavitation or restorations .","22 Years","55 Years",{"count":104,"type":21},20,[24],"This study will be conducted to Clinically evaluate Bioactive Silica Based with calcium booster (Refix technology) toothpaste and Sodium Fluoride varnish versus conventional fluoride toothpastes in management of white spot lesions of adult patients over 6m follow up and evaluating patient perception regarding the treatment provided.",[108,27],"Caries; Initial",[110,111,112],"Bioactive Silica Based with calcium booster (Refix technology) toothpaste","Caries Prevention","white spot carious lesions","2025-08-06",{"date":115,"type":34},"2025-08-13",{"date":117,"type":21},"2025-08-15",{"date":119,"type":21},"2026-03-01",{"name":121,"class":41},"Rawda Hesham Abd ElAziz",{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":77,"sex":16,"minAge":129,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":132,"phases":4,"briefSummary":133,"conditions":134,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":144,"locationsCount":4},"100596667","surface-caries-feature-study-100596667","NCT07048444","Surface Caries Feature Study","Data Collection for a Surface Caries Detection Software","Inclusion Criteria:\n\n* Willing and able to give informed consent for participation in the study\n* Male or female, aged 18 years or above\n* Patients looking for dental treatment\n* Good general health (i.e. absence of any condition that the Principal Investigator evaluates as a risk either to the subject or to the data quality)\n* Able (in the Investigator's opinion) and willing to comply with all study requirements.\n* Minimum of 15 natural teeth without crowns\n* At least one cavitated caries lesion\n\nExclusion Criteria:\n\n* Patients with orthodontic appliances and permanent retainers\n* Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study)\n* Patients who are not able or willing to sign the Informed Consent\n* Patients who are currently pregnant. A urine pregnancy test will be administered during the study visit for woman who could be pregnant","18 Years",{"count":131,"type":21},88,"OBSERVATIONAL","Dental caries (dental cavity) is very common and can impact oral health and oral health-related quality of life. Dental caries is when the tooth surfaces break down, and if left untreated, can cause tooth pain. In routine clinical practice, dental professionals typically assess caries lesions by looking at patients' teeth, touching the areas of interest with a dental probe, and running a probe over the teeth to check the buildup of bacteria.\n\nDentists often use x-rays to help find cavities, and they can also take pictures of the teeth to show what the problem looks like.\n\nNew tools called intraoral scanners are becoming more useful for finding cavities. These scanners do not use radiation and do not hurt. Some computer programs that use artificial intelligence (AI) can also help dentists find cavities. AI can study the spots on patients' teeth and help make better, faster decisions. The purpose of this study is to collect data that will be used to develop and test an AI software that can help dentists in the detection of caries.",[27,135,136,108,137],"Caries Root","Caries,Dental","Caries Assessment","2025-07-01",{"date":140,"type":34},"2025-07-02",{"date":142,"type":21},"2025-07-22",{"date":119,"type":21},{"name":145,"class":146},"3Shape A\u002FS","INDUSTRY"]