[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"caries-assessment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:caries-assessment":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100619282","evaluation-of-radiation-free-caries-detection-integrated-into-intraoral-scanners-compared-with-conventional-diagnostic-methods-100619282",false,"NCT07342595","Evaluation of Radiation-Free Caries Detection Integrated Into Intraoral Scanners Compared With Conventional Diagnostic Methods","Clinical Performance of an Intraoral Scanner With Integrated Caries Detection","Inclusion Criteria:\n\n* All genders, minimum age for participation is 18 years\n* Presence of a tooth, that is already scheduled for extraction (indication for extraction diagnosed during the normal clinical service independently of this study by a qualified dentist)\n* Availability of a radiograph (X-ray) showing the tooth to be extracted along with adjacent teeth\n* Signed informed consent after a comprehensive explanation of the study is available\n\nExclusion Criteria:\n\n* participants under the age of 18\n* Addicts or participants with impaired cognitive abilities that do not allow the participant to assess the scope of the study",true,"ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this study is to evaluate if an intraoral scanning device with an integrated radiation-free caries detection tool (near-infrared light) can detect early tooth decay.\n\nThe main questions it aims to answer are:\n\nCan the tool find tooth decay as accurately as traditional visual and X-ray examinations? How reliable is the tool when used by different dentists?\n\nParticipants will:\n\n* Have one tooth scheduled for extraction. This tooth and its adjacent teeth need to be examined before the extraction by using the intraoral scanner with the caries detection tool, which takes about 5 extra minutes. Those results will be compared to the standard dental examination, including visual inspection and X-rays.\n* Allow investigators to check the extracted tooth and the neighboring teeth directly after extraction to see if any carious lesion is visible.\n\nThis study does not involve any drugs or invasive procedures beyond the planned tooth extraction, and participants will not be exposed to extra radiation. The results will help dentists detect tooth decay, which may allow less invasive treatments and better prevention.",[27,28,29],"Caries Assessment","Caries; Dentin","Caries; Initial",[31,32,33],"Caries detection","near-infrared light","clinical performance","NOT_YET_RECRUITING","2026-01-13",{"date":37,"type":38},"2026-01-15","ACTUAL",{"date":40,"type":21},"2026-04",{"date":42,"type":21},"2027-07",{"name":44,"class":45},"Albert Mehl","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100618024","effects-of-silver-diamine-fluoride-and-intraoral-cryotherapy-on-local-anesthesia-in-mih-affected-molars-100618024","NCT07326241","Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia in MIH-Affected Molars","Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia Efficacy in Permanent Molars With Molar-Incisor Hypomineralization","Inclusion Criteria:\n\n* Children aged between 6 and 12 years.\n* Systemically healthy children with no medical conditions that could interfere with dental treatment.\n* Presence of at least one permanent first molar affected by molar-incisor hypomineralization (MIH), diagnosed according to the European Academy of Paediatric Dentistry (EAPD) criteria.\n* Teeth with caries lesions classified as ICDAS II codes 2, 3, 4, 5, or 6.\n* Children with an adequate level of cooperation to allow completion of dental treatment under clinical conditions.\n* Children and their parents\u002Flegal guardians who have read, understood, and signed the informed consent form and agreed to participate in the study.\n\nExclusion Criteria:\n\n* Teeth that are not restorable.\n* Children with a known allergy or hypersensitivity to any materials used in the study, including local anesthetics, silver diamine fluoride, or restorative materials.\n* Presence of spontaneous pain, percussion sensitivity, or other signs\u002Fsymptoms of pulpal pathology in the study tooth.\n* Children with systemic diseases or conditions that could affect pain perception, healing, or cooperation during dental treatment.\n* Children who are unable or unwilling to complete the clinical procedure.","6 Years","12 Years",{"count":57,"type":21},75,[24],"Molar-incisor hypomineralization (MIH) is a developmental enamel defect of unclear etiology that affects permanent first molars and often permanent incisors, leading to increased porosity, hypersensitivity, and poor prognosis. The porous structure of MIH-affected enamel facilitates bacterial penetration, which may cause subclinical pulpal inflammation and reduce the effectiveness of local anesthesia during dental procedures. Achieving adequate anesthesia in children with MIH can be challenging, resulting in increased discomfort, anxiety, and behavioral management difficulties.\n\nCryotherapy has been shown to reduce pain by decreasing local inflammation and slowing nerve conduction, while silver diamine fluoride (SDF) has demonstrated efficacy in reducing dentin hypersensitivity through tubule occlusion, antibacterial activity, and remineralization. This study aims to evaluate the effects of intraoral cryotherapy and silver diamine fluoride application on pain perception and the efficacy of local anesthesia during operative dental procedures in MIH-affected permanent first molars.",[61,62,27],"MIH","Molar-Incisor Hypomineralization","2025-12-24",{"date":65,"type":38},"2026-01-08",{"date":67,"type":21},"2026-02-01",{"date":69,"type":21},"2026-04-01",{"name":71,"class":45},"Çanakkale Onsekiz Mart University",2,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":4},"100596667","surface-caries-feature-study-100596667","NCT07048444","Surface Caries Feature Study","Data Collection for a Surface Caries Detection Software","Inclusion Criteria:\n\n* Willing and able to give informed consent for participation in the study\n* Male or female, aged 18 years or above\n* Patients looking for dental treatment\n* Good general health (i.e. absence of any condition that the Principal Investigator evaluates as a risk either to the subject or to the data quality)\n* Able (in the Investigator's opinion) and willing to comply with all study requirements.\n* Minimum of 15 natural teeth without crowns\n* At least one cavitated caries lesion\n\nExclusion Criteria:\n\n* Patients with orthodontic appliances and permanent retainers\n* Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study)\n* Patients who are not able or willing to sign the Informed Consent\n* Patients who are currently pregnant. A urine pregnancy test will be administered during the study visit for woman who could be pregnant",{"count":81,"type":21},88,"OBSERVATIONAL","Dental caries (dental cavity) is very common and can impact oral health and oral health-related quality of life. Dental caries is when the tooth surfaces break down, and if left untreated, can cause tooth pain. In routine clinical practice, dental professionals typically assess caries lesions by looking at patients' teeth, touching the areas of interest with a dental probe, and running a probe over the teeth to check the buildup of bacteria.\n\nDentists often use x-rays to help find cavities, and they can also take pictures of the teeth to show what the problem looks like.\n\nNew tools called intraoral scanners are becoming more useful for finding cavities. These scanners do not use radiation and do not hurt. Some computer programs that use artificial intelligence (AI) can also help dentists find cavities. AI can study the spots on patients' teeth and help make better, faster decisions. The purpose of this study is to collect data that will be used to develop and test an AI software that can help dentists in the detection of caries.",[85,86,87,29,27],"Caries Active","Caries Root","Caries,Dental","2025-07-01",{"date":90,"type":38},"2025-07-02",{"date":92,"type":21},"2025-07-22",{"date":94,"type":21},"2026-03-01",{"name":96,"class":97},"3Shape A\u002FS","INDUSTRY"]