[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"caries-initial\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:caries-initial":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100619282","evaluation-of-radiation-free-caries-detection-integrated-into-intraoral-scanners-compared-with-conventional-diagnostic-methods-100619282",false,"NCT07342595","Evaluation of Radiation-Free Caries Detection Integrated Into Intraoral Scanners Compared With Conventional Diagnostic Methods","Clinical Performance of an Intraoral Scanner With Integrated Caries Detection","Inclusion Criteria:\n\n* All genders, minimum age for participation is 18 years\n* Presence of a tooth, that is already scheduled for extraction (indication for extraction diagnosed during the normal clinical service independently of this study by a qualified dentist)\n* Availability of a radiograph (X-ray) showing the tooth to be extracted along with adjacent teeth\n* Signed informed consent after a comprehensive explanation of the study is available\n\nExclusion Criteria:\n\n* participants under the age of 18\n* Addicts or participants with impaired cognitive abilities that do not allow the participant to assess the scope of the study",true,"ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this study is to evaluate if an intraoral scanning device with an integrated radiation-free caries detection tool (near-infrared light) can detect early tooth decay.\n\nThe main questions it aims to answer are:\n\nCan the tool find tooth decay as accurately as traditional visual and X-ray examinations? How reliable is the tool when used by different dentists?\n\nParticipants will:\n\n* Have one tooth scheduled for extraction. This tooth and its adjacent teeth need to be examined before the extraction by using the intraoral scanner with the caries detection tool, which takes about 5 extra minutes. Those results will be compared to the standard dental examination, including visual inspection and X-rays.\n* Allow investigators to check the extracted tooth and the neighboring teeth directly after extraction to see if any carious lesion is visible.\n\nThis study does not involve any drugs or invasive procedures beyond the planned tooth extraction, and participants will not be exposed to extra radiation. The results will help dentists detect tooth decay, which may allow less invasive treatments and better prevention.",[27,28,29],"Caries Assessment","Caries; Dentin","Caries; Initial",[31,32,33],"Caries detection","near-infrared light","clinical performance","NOT_YET_RECRUITING","2026-01-13",{"date":37,"type":38},"2026-01-15","ACTUAL",{"date":40,"type":21},"2026-04",{"date":42,"type":21},"2027-07",{"name":44,"class":45},"Albert Mehl","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100602187","clinical-effectiveness-of-bioactive-silica-based-with-calcium-toothpaste-100602187","NCT07120243","Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste","Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste, Sodium Fluoride Varnish in Management of White Spot Lesions (A 6m Randomized Clinical Trial).","Inclusion Criteria:\n\n* Patient with non cavitated carious WSL in at least one upper or lower tooth.\n* Teeth with active non cavitated white spot carious lesions on the cervical one third of the facial or lingual surfaces.\n\nTeeth with initial carious lesions with score 1 or 2 according to The International Caries Detection and Assessment System (ICDAS).\n\n• Teeth with Diagnodent values between 14-20 that refers to early enamel caries.\n\nExclusion Criteria:\n\nPatients with known allergies or adverse reactions to any ingredient of the tested materials.\n\n• Systematic disease and\u002F or physical disabilities that may affect participation.\n\n• Patients with white spots due to congenital reasons e.g. enamel hypomineralization.\n\n• Pregnant females with frequent vomiting attacks.\n\n• Smokers.\n\n• Excessive dietary or environmental exposure to acids.\n\n* Presence of surface cavitation or restorations .","22 Years","55 Years",{"count":57,"type":21},20,[24],"This study will be conducted to Clinically evaluate Bioactive Silica Based with calcium booster (Refix technology) toothpaste and Sodium Fluoride varnish versus conventional fluoride toothpastes in management of white spot lesions of adult patients over 6m follow up and evaluating patient perception regarding the treatment provided.",[29,61],"Caries Active",[63,64,65],"Bioactive Silica Based with calcium booster (Refix technology) toothpaste","Caries Prevention","white spot carious lesions","2025-08-06",{"date":68,"type":38},"2025-08-13",{"date":70,"type":21},"2025-08-15",{"date":72,"type":21},"2026-03-01",{"name":74,"class":45},"Rawda Hesham Abd ElAziz",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":84,"phases":4,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":95,"locationsCount":4},"100596667","surface-caries-feature-study-100596667","NCT07048444","Surface Caries Feature Study","Data Collection for a Surface Caries Detection Software","Inclusion Criteria:\n\n* Willing and able to give informed consent for participation in the study\n* Male or female, aged 18 years or above\n* Patients looking for dental treatment\n* Good general health (i.e. absence of any condition that the Principal Investigator evaluates as a risk either to the subject or to the data quality)\n* Able (in the Investigator's opinion) and willing to comply with all study requirements.\n* Minimum of 15 natural teeth without crowns\n* At least one cavitated caries lesion\n\nExclusion Criteria:\n\n* Patients with orthodontic appliances and permanent retainers\n* Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study)\n* Patients who are not able or willing to sign the Informed Consent\n* Patients who are currently pregnant. A urine pregnancy test will be administered during the study visit for woman who could be pregnant",{"count":83,"type":21},88,"OBSERVATIONAL","Dental caries (dental cavity) is very common and can impact oral health and oral health-related quality of life. Dental caries is when the tooth surfaces break down, and if left untreated, can cause tooth pain. In routine clinical practice, dental professionals typically assess caries lesions by looking at patients' teeth, touching the areas of interest with a dental probe, and running a probe over the teeth to check the buildup of bacteria.\n\nDentists often use x-rays to help find cavities, and they can also take pictures of the teeth to show what the problem looks like.\n\nNew tools called intraoral scanners are becoming more useful for finding cavities. These scanners do not use radiation and do not hurt. Some computer programs that use artificial intelligence (AI) can also help dentists find cavities. AI can study the spots on patients' teeth and help make better, faster decisions. The purpose of this study is to collect data that will be used to develop and test an AI software that can help dentists in the detection of caries.",[61,87,88,29,27],"Caries Root","Caries,Dental","2025-07-01",{"date":91,"type":38},"2025-07-02",{"date":93,"type":21},"2025-07-22",{"date":72,"type":21},{"name":96,"class":97},"3Shape A\u002FS","INDUSTRY"]