[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cariesdental\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cariesdental":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,17,0,[8,45,70,91,117,144,179,200,225,247,270,296,318,342,363,387,413],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100642087","artificial-intelligence-ai-for-proximal-caries-detection-and-its-impact-on-treatment-threshold-100642087",false,"NCT07648212","Artificial Intelligence (AI) for Proximal Caries Detection and Its Impact on Treatment Threshold","Artificial Intelligence for Proximal Caries Detection and Its Impact on Treatment Threshold: Randomized Trial","Early learner Inclusion Criteria:\n\n* Provide informed consent\n* Willing to comply with all study procedures and be available for the duration of the study\n* Dental student in second, third, or fourth year of dental school at University of Michigan School of Dentistry\n\nLate learner Inclusion Criteria:\n\n* Provide informed consent\n* Willing to comply with all study procedures and be available for the duration of the study\n* Dental resident or junior faculty having at least 2 years of clinical experience outside of a dental education setting\n\nExclusion Criteria for participants:\n\n* Dental students who do not have previous experience with caries detection (such as first year dental students)\n* Residents that do not have frequent exposure to caries detection, such as orthodontic, periodontic, oral surgery graduate residents.","ALL","18 Years","99 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to assess the impact of artificial intelligence on proximal caries detection and subsequent treatment decisions of early learners and compare those with outcomes of experienced learners.",[27],"Caries,Dental",[29,30,31],"Artificial intelligence","Dental students (years 2-4)","Dental resident or junior faculty","NOT_YET_RECRUITING","2026-06-09",{"date":35,"type":36},"2026-06-15","ACTUAL",{"date":38,"type":21},"2026-06",{"date":40,"type":21},"2027-05",{"name":42,"class":43},"University of Michigan","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":44},"100617808","efficacy-of-a-chitosan-dressing-in-pulpotomy-of-immature-permanent-teeth-100617808","NCT07323433","Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth","Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth:Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients with immature maxillary anterior teeth.\n* Patients with caries or traumatic exposed teeth .\n* Patients should be free from any systemic disease that may affect normal healing and predictable outcome class I ASA .\n* Patients who will agree to the consent and will commit to follow-up period.\n\nExclusion Criteria:\n\n* Patients with mature roots.\n* Patients with any systemic disease that may affect normal healing.\n* Patients with signs of periapical inflammation.\n* Patients who could\u002Fwould not participate in a 1-year follow-up.\n* Teeth with periodontal involvement.\n* Teeth with vertical root fractures.\n* Non- restorable teeth.\n* cases with previously initiated endodontic treatment.",true,"7 Years","15 Years",{"count":56,"type":21},26,[24],"Immature permanent teeth, also known as young permanent teeth, are used to describe teeth with incomplete root formation. Immature permanent teeth are prone to caries and trauma which can cause exposure and degeneration of pulp. Pulp degeneration stops root formation, leaving teeth with open apex. It is vital to preserve the pulp vitality otherwise the incompletion of root might result in the fragility of teeth. Pulpotomy is one of the most widely used methods in preserving vital pulp in teeth, which is of great significance in achieving continue root formation in immature permanent teeth suffering from dental caries or trauma. Pulpotomy is recommended by the American Association of Pediatric Dentistry for the management of pulp exposure in immature permanent teeth to achieve apexogenesis (continued root formation and closure of apex). In this procedure, coronal pulp tissue is removed in order to eliminate the infected or contaminated pulp and to reach the healthy vital pulp followed by coverage with biocompatible material.",[27],"RECRUITING","2025-12-31",{"date":63,"type":36},"2026-01-07",{"date":65,"type":36},"2025-08-25",{"date":67,"type":21},"2026-08-25",{"name":69,"class":43},"Minia University",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":52,"sex":16,"minAge":77,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":79,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":44},"100527770","caries-detection-with-two-different-caries-detecting-devices-100527770","NCT06152081","Caries Detection With Two Different Caries Detecting Devices","A Pilot Clinical Trial Comparing the Efficacy of Caries Detection With a Novel Caries Detecting Rinse and Existing Diagnostic Tools","Inclusion Criteria:\n\n* Patients of TUSDM Comprehensive Care Clinic\n* Adult patients over the age of 21\n* Extreme\u002FHigh Caries Risk classification per TUSDM Caries Management by Risk Assessment (CAMBRA) form\n* Presence of 2 or more initial active primary carious lesions on a free coronal surface of any tooth by visual assessment, QLF, and LumiCare™\n* Presence of at least 1 cavitated lesion\n* Updated (no more than 6 months old) bite wing radiographs available.\n* Patients who responded either yes\u002Fno to use of e-cigarettes\u002Fvapes\n* 1 active caries, 1 inactive caries and 1 sound tooth surface.\n\nExclusion Criteria:\n\n* Low or moderate caries risk classification per TUSDM CAMBRA form\n* No clinically detectable carious lesions on free coronal surfaces\n* No cavitated caries lesions\n* Carious teeth with caries lesions concomitant with extrinsic stains, fluorosis, or developmental defects.\n* Patients who responded yes to the use of conventional cigarettes or smokeless tobacco","21 Years",{"count":20,"type":21},[24],"The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression. The secondary aim is to compare the progression of carious lesions between patients who reported use of e-cigarettes\u002Fvapes and those who did not.",[27],"2025-08-04",{"date":84,"type":36},"2025-08-05",{"date":86,"type":36},"2025-04-01",{"date":88,"type":21},"2027-10",{"name":90,"class":43},"Tufts University",{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":4,"eligibilityCriteria":97,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":98,"targetDuration":4,"studyType":100,"phases":4,"briefSummary":101,"conditions":102,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":4},"100596667","surface-caries-feature-study-100596667","NCT07048444","Surface Caries Feature Study","Data Collection for a Surface Caries Detection Software","Inclusion Criteria:\n\n* Willing and able to give informed consent for participation in the study\n* Male or female, aged 18 years or above\n* Patients looking for dental treatment\n* Good general health (i.e. absence of any condition that the Principal Investigator evaluates as a risk either to the subject or to the data quality)\n* Able (in the Investigator's opinion) and willing to comply with all study requirements.\n* Minimum of 15 natural teeth without crowns\n* At least one cavitated caries lesion\n\nExclusion Criteria:\n\n* Patients with orthodontic appliances and permanent retainers\n* Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study)\n* Patients who are not able or willing to sign the Informed Consent\n* Patients who are currently pregnant. A urine pregnancy test will be administered during the study visit for woman who could be pregnant",{"count":99,"type":21},88,"OBSERVATIONAL","Dental caries (dental cavity) is very common and can impact oral health and oral health-related quality of life. Dental caries is when the tooth surfaces break down, and if left untreated, can cause tooth pain. In routine clinical practice, dental professionals typically assess caries lesions by looking at patients' teeth, touching the areas of interest with a dental probe, and running a probe over the teeth to check the buildup of bacteria.\n\nDentists often use x-rays to help find cavities, and they can also take pictures of the teeth to show what the problem looks like.\n\nNew tools called intraoral scanners are becoming more useful for finding cavities. These scanners do not use radiation and do not hurt. Some computer programs that use artificial intelligence (AI) can also help dentists find cavities. AI can study the spots on patients' teeth and help make better, faster decisions. The purpose of this study is to collect data that will be used to develop and test an AI software that can help dentists in the detection of caries.",[103,104,27,105,106],"Caries Active","Caries Root","Caries; Initial","Caries Assessment","2025-07-01",{"date":109,"type":36},"2025-07-02",{"date":111,"type":21},"2025-07-22",{"date":113,"type":21},"2026-03-01",{"name":115,"class":116},"3Shape A\u002FS","INDUSTRY",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":16,"minAge":124,"maxAge":125,"enrollmentInfo":126,"targetDuration":4,"studyType":22,"phases":128,"briefSummary":129,"conditions":130,"keywords":131,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":44},"100365642","ozone-application-before-fissure-sealants-100365642","NCT04040920","Ozone Application Before Fissure Sealants","The Effect of Ozone Application Before Fissure Sealants: a Split Mouth Randomized Controlled Trial","Inclusion Criteria:\n\n* first or second secondary molars to be sealed\n* possibility to isolate with rubber dam both the teeth involved\n* no clear signs of pigmentations\n* good general health\n\nExclusion Criteria:\n\n* latex allergy\n* epilepsy or other severe neurological pathologies\n* psychiatric disease\n* excessive sensibility to electrical current\n* severe asthma\n* enamel disorders, such as amelogenesis imperfect, white spots, fluorosis or Molar Incisors Hypomineralization","6 Years","16 Years",{"count":127,"type":21},67,[24],"Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces. Decays generally evolve in fissures and pits of secondary molars. Pits and fissure sealants prevent decays if performed in two years from eruption. Ozone has bactericidal effect and remineralizing capacity on enamel.\n\nThe aim of this study is to assess the effectiveness of ozone application before sealants in increasing their duration in time.",[27],[132,133,134],"Ozone","Pits and fissures sealants","Prevention","2025-05-13",{"date":137,"type":36},"2025-05-16",{"date":139,"type":36},"2019-06-17",{"date":141,"type":21},"2026-12-31",{"name":143,"class":43},"IRCCS Burlo Garofolo",{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":150,"eligibilityCriteria":151,"healthyVolunteers":52,"sex":16,"minAge":152,"maxAge":153,"enrollmentInfo":154,"targetDuration":4,"studyType":22,"phases":156,"briefSummary":157,"conditions":158,"keywords":162,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":177,"locationsCount":44},"100550894","comparative-evaluation-of-smart-hall-technique-vs-conventional-ss-crown-in-primary-molars-a-randomized-clinical-trial-100550894","NCT06453005","Comparative Evaluation of SMART Hall Technique Vs. Conventional SS Crown in Primary Molars: a Randomized Clinical Trial","Comparative Evaluation of SMART Hall Technique Versus Conventional SS Crown Restoration in Treatment of Carious Primary Molars - a Randomized Clinical Trial","RCT","Inclusion Criteria:\n\n1. Children aged 3 to 9 years old.\n2. Presence of occluso-proximal carious lesions (ICDAS CODE 3\u002F4\u002F5) in one or more primary molars, confirmed through clinical examination and radiographic assessment.\n3. Requirement for restorative treatment in the form of either the SMART Hall technique or standard stainless steel crown (SSC) restoration, as determined by clinical assessment.\n4. Willingness and ability of the parent\u002Fguardian to provide informed consent and ensure the child's attendance at follow-up appointments.\n5. Adequate cooperation of the child during dental treatment and evaluation procedures, as determined by the clinician.\n\nExclusion Criteria:\n\n1. Presence of severe systemic medical conditions (e.g., uncontrolled diabetes, immunodeficiency disorders) that may compromise treatment outcomes or pose risks during dental procedures.\n2. Use of medications known to interfere with dental treatment or healing, such as anticoagulants or immunosuppressants, unless medically managed and deemed safe by the treating healthcare provider.\n3. History of adverse reactions to dental materials or procedures that may contraindicate participation in the study.\n4. Inability of the child to tolerate local anesthesia or undergo dental treatment due to psychological, behavioral, or developmental factors.\n5. Presence of extensive dental caries or additional oral pathologies requiring urgent or specialized dental care beyond the scope of the study.","3 Years","9 Years",{"count":155,"type":21},30,[24],"Dental caries, particularly in primary molars, significantly affects children's oral health and overall well-being. Traditional management with stainless steel crowns (SSCs) involves significant tooth reduction and advanced dental skills. Introduced in the 1970s, the Hall technique offers a less invasive alternative, minimizing tooth reduction compared to SSCs.\n\nThe SMART Hall technique represents a further evolution, emphasizing atraumatic cavity preparation using hand instruments. It offers advantages like minimal or no tooth reduction, minimized discomfort, improved patient cooperation, shorter treatment times, and cost-effectiveness.\n\nSilver Diamine Fluoride (SDF) emerges as a promising non-invasive approach for managing dental caries in primary teeth, though it may cause temporary tooth discoloration. However, comparative evaluation with traditional SSC restorations remains limited.\n\nTo address this gap, a randomized clinical trial will evaluate the treatment outcomes of the SMART Hall technique versus conventional SSC restoration for managing occluso-proximal carious lesions (ICDAS CODE 3\u002F4\u002F5) in primary molars of young patients. Children aged 3 to 9 years requiring restorations will be included, assessing clinical outcomes, treatment time duration, and radiographical outcomes of both techniques at specific follow-up intervals of 3 months \\& 6 months.\n\nThis split mouth study will explore Clinical outcomes, radiographical outcomes, treatment time duration, and patient's pain perception with the chosen treatment modality. The findings will provide insights into the effectiveness and feasibility of the SMART Hall technique compared to the traditional SSC approach, informing evidence-based decision-making in pediatric dentistry and influencing treatment recommendations for preserving the health and function of primary molars in young children.",[27,159,160,161],"Pain","Plaque, Dental","Gingival Bleeding",[163,164,165,166,167,168,169,170],"Randomized Clinical Trial","Dental caries","Primary molars","Stainless Steel Crowns","SMART Hall Technique","Conventional Technique","Silver Diamine Fluoride","Split Mouth Study","2025-02-27",{"date":173,"type":36},"2025-03-03",{"date":175,"type":36},"2024-01-30",{"date":86,"type":21},{"name":178,"class":43},"C K S Teja Institute Of Dental Sciences & Research",{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":186,"enrollmentInfo":187,"targetDuration":4,"studyType":100,"phases":4,"briefSummary":189,"conditions":190,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":198,"locationsCount":4},"100580506","caries-associated-saliva-biomarkers-among-different-races-100580506","NCT06838182","Caries-associated Saliva Biomarkers Among Different Races","Caries-associated Saliva Biomarkers in Caries Experienced and Caries Free Population Among Different Races: Diagnostic Accuracy Study","Inclusion Criteria:\n\n* Age : 19-25\n* We will have 2 groups according to ICDAS classification : Not severe (ICDAS score ≤3) \u002F Severe (ICDAS score ≥3)\n\nExclusion Criteria:\n\n* : Those who reported daily use of alcohol or tobacco .\n* Those who used antibiotics or other systemic drugs within the previous three months .\n* Those who regularly used antiseptics","25 Years",{"count":188,"type":21},22,"discover possible differences and develop effective preventative interventions by examining the relationship between salivary biomarkers and caries prevalence across different racial groups and Detect risk factors involved in caries incidence .",[27],"2025-02-19",{"date":193,"type":36},"2025-02-20",{"date":195,"type":21},"2025-02-25",{"date":197,"type":21},"2025-04-25",{"name":199,"class":43},"Cairo University",{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":52,"sex":16,"minAge":124,"maxAge":206,"enrollmentInfo":207,"targetDuration":4,"studyType":22,"phases":208,"briefSummary":209,"conditions":210,"keywords":211,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":216,"lastUpdatePostDateStruct":217,"startDateStruct":219,"completionDateStruct":221,"leadSponsor":223,"locationsCount":44},"100579604","effect-of-ercrysgg-sub-ablative-laser-irradiation-on-fissure-caries-prevention-in-permanent-molars-100579604","NCT06826456","Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars","Inclusion Criteria:\n\n* Participants of age 6-12 years old\n* Patients ranking definitely positive or positive on Frankl behavior rating scale\n* Having at least two bilateral fully erupted first permanent molars with untreated non-cavitated occlusal surfaces with deep grooves, the included teeth will have International Detection and Assessment System (ICDAS-II)\u002F severity scores 0, 1 or 2\n* Initial DIAGNOdent Score not exceeding value of 25 indicating only enamel involvement\n* Patients whom their parents are willing to comply with all study procedures and protocols and will be given an informed consent to participate\n\nExclusion Criteria:\n\n* Patients with any known medical history of systemic diseases\n* Patients having first permanent molar with hypoplastic or hypocalcified enamel\n* Patients using medications that may affect the oral flora or salivary flow\n* Patients treated with in-office fluoride treatment within the last 3 months prior to being enrolled in the study.\n* Patients showing evidence of poor oral hygiene according to Silness and Löe plaque index","12 Years",{"count":20,"type":21},[24],"Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries prevention.\n\nThe aim of this study: This study aims to evaluate the effect of Er,Cr:YSGG subablative laser irradiation on caries resistance of occlusal fissures of permanent molars.\n\nMaterials and methods: In-vivo study, a split mouth randomized controlled trial with sixty patients having two fully erupted bilateral first permanent molars (ICDAS-II score 0,1 or 2). The pits and fissures will be subjected to sub-ablative power of Er,Cr:YSGG Laser (Group 1, n=90) and will be compared with fluoride varnish application on the first permanent molars in the same arch(Group 2,n=90). DIAGNOdentTM readings and changes in ICDAS-II score will be assessed at base line and at 3,6,9 and 12 months follow-up.",[27],[212,213,214,215],"Er,Cr:YSGG","laser","DIAGNOdentTM","acid resistance","2025-02-12",{"date":218,"type":36},"2025-02-14",{"date":220,"type":36},"2024-01-01",{"date":222,"type":21},"2025-08",{"name":224,"class":43},"Alexandria University",{"id":226,"slug":227,"hasResults":11,"nctId":228,"briefTitle":229,"officialTitle":230,"acronym":4,"eligibilityCriteria":231,"healthyVolunteers":11,"sex":16,"minAge":232,"maxAge":233,"enrollmentInfo":234,"targetDuration":4,"studyType":100,"phases":4,"briefSummary":236,"conditions":237,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":4},"100570001","coronal-and-radicular-caries-prevalence-and-related-risk-factor-in-diabetic-patient-100570001","NCT06701565","Coronal and Radicular Caries Prevalence and Related Risk Factor in Diabetic Patient","Coronal and Radicular Caries Prevalence With Related Risk Factors Among Middle Age Type II Diabetic Patients Attending National Institute of Diabetes and Endocrinology: a Hospital Based Cross Sectional Study","Inclusion Criteria:\n\n1. Patient whose age between 30-65\n2. Diabetic patients\n3. Patient consulting in the outpatient clinic\n4. Co-operative patient\n5. Males \\& Females\n6. Egyptian\n\nExclusion Criteria:\n\n1. Patients under or over this age group\n2. Lack of compliance\n3. Disabilities\n4. Pregnant women","35 Years","60 Years",{"count":235,"type":21},265,"This study aims to investigate the prevalence and risk factors of coronal and radicular caries in middle-aged individuals with Type 2 diabetes. It focuses on how poor blood sugar control, reduced saliva production, increased plaque accumulation, and periodontal disease contribute to a higher risk of dental decay in this population. The study examines the relationship between glycemic control (e.g., HbA1c levels) and the severity of caries, as well as the impact of diabetes-related changes in oral health, such as gum recession and dry mouth, on the development of both coronal and radicular caries. The findings could inform preventive strategies and dental care guidelines tailored for diabetic patients.",[27,104,238],"Diabetes Mellitus, Type 2","2024-12-02",{"date":241,"type":36},"2024-12-04",{"date":243,"type":21},"2024-12-15",{"date":245,"type":21},"2025-06-15",{"name":199,"class":43},{"id":248,"slug":249,"hasResults":11,"nctId":250,"briefTitle":251,"officialTitle":252,"acronym":4,"eligibilityCriteria":253,"healthyVolunteers":52,"sex":16,"minAge":254,"maxAge":233,"enrollmentInfo":255,"targetDuration":257,"studyType":100,"phases":4,"briefSummary":258,"conditions":259,"keywords":260,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":262,"lastUpdatePostDateStruct":263,"startDateStruct":265,"completionDateStruct":267,"leadSponsor":269,"locationsCount":4},"100567422","artificial-intellegence-rivals-digital-bitewing-in-detect-secondary-caries-100567422","NCT06667986","Artificial Intellegence Rivals Digital Bitewing in Detect Secondary Caries","AI Rivals Traditional Bite Wing Radiography in Detecting Proximal Secondary Caries in A Group of Egyptian Patients at Cairo University, Faculty OF Dentistry Hospital (Diagnostic Accuracy Study)","Inclusion Criteria:\n\n1. Adult Patients Aged 22-60 Patient\n2. Males or females.\n3. Patients have proximal restorations.\n4. Co-operative patients who show interest in participating in the study.\n\nExclusion Criteria:\n\n1. Patients with orthodontic appliances, or bridge work that might interfere with evaluation\n2. Patients with no caries.\n3. Systematic disease that may affect participation.\n4. Patients not willing to be part of the study or ones who refuse to sign the informed consent.","22 Years",{"count":256,"type":21},322,"1 Year","This study uses digital bitewing radiography as a standard for diagnosing proximal secondary caries. Patients will undergo imaging with a parallel technique and fixed settings to ensure high-quality, consistent images. Radiographs are interpreted by experienced dental professionals to maintain diagnostic accuracy. Machine learning models YOLO and Mask-RCNN will analyze these images in three phases: pre-analytical, analytical, and post-analytical. A dataset of 322 labeled images, annotated by experts, is used to train these models. Data augmentation methods enhance model performance, and accuracy is assessed against radiographic results to confirm reliability.",[27],[261],"Secondary caries, Artificial intelligence, Digital bitewing radiography, Diagnostic accuracy study.","2024-10-30",{"date":264,"type":36},"2024-10-31",{"date":266,"type":21},"2024-11-15",{"date":268,"type":21},"2026-02-15",{"name":199,"class":43},{"id":271,"slug":272,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":4,"eligibilityCriteria":276,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":277,"targetDuration":4,"studyType":22,"phases":279,"briefSummary":280,"conditions":281,"keywords":285,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":44},"100566021","oral-health-education-and-message-framing-effect-on-oral-health-status-of-refugees-in-egypt-100566021","NCT06649760","Oral Health Education and Message Framing Effect on Oral Health Status of Refugees in Egypt","Effect of Message Framing Through M-Health on Oral Health Conditions and Oral Health Related Quality of Life Among Refugees in Alexandria, Egypt: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Refugees older than 18 years old.\n* From Arabic speaking countries.\n* Has been resident in Alexandria, Egypt for at least 6 months.\n* Having mobile phones to receive text messages.\n* Agrees to participate in the study.\n\nExclusion Criteria:\n\n* Planning to move away during 1 year study period.\n* Participating in any kind of oral health education and promotion programs.",{"count":278,"type":21},510,[24],"Refugees, facing forced displacement and often exposed to traumatic experiences, represent a vulnerable population with unique healthcare needs. Oral health is considered a prominent factor that contributes to quality of life.\n\nTherefore, this study aim at assessing the effect of message framing on enhancing oral health practices in a group of refugees in Alexandria, Egypt. A three-arm cluster randomized controlled clinical trial will compare a gain-framed mobile text messages group, a loss-framed mobile text messages group, and a control group. The primary outcome is the improvement in oral health practices measured by changes in dental plaque and secondary outcome is to assess change in oral health-related quality of life. In addition, oral health knowledge, attitudes, and practices of refugees will be assessed.",[282,27,160,283,284],"Knowledge, Attitudes, Practice","Gingivitis","Pocket, Periodontal",[164,286,287,283],"Plaque","KAP","2024-10-17",{"date":290,"type":36},"2024-10-21",{"date":292,"type":36},"2024-06-29",{"date":294,"type":21},"2025-06",{"name":224,"class":43},{"id":297,"slug":298,"hasResults":11,"nctId":299,"briefTitle":300,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":52,"sex":16,"minAge":152,"maxAge":153,"enrollmentInfo":302,"targetDuration":4,"studyType":22,"phases":304,"briefSummary":305,"conditions":306,"keywords":307,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":309,"lastUpdatePostDateStruct":310,"startDateStruct":312,"completionDateStruct":314,"leadSponsor":316,"locationsCount":44},"100562015","comparison-of-the-treatment-outcomes-of-the-conventional-stainless-steel-crown-restorations-and-the-hall-technique-in-the-treatment-of-carious-primary-molars-100562015","NCT06597669","Comparison of the Treatment Outcomes of the Conventional Stainless Steel Crown Restorations and the Hall Technique in the Treatment of Carious Primary Molars","Inclusion Criteria:\n\n1. Agree and voluntarily participate in the research (with the patient's parent\u002Fguardian consent for participation)\n2. Children have a primary molar with at least 2 carious lesions corresponding to International Caries Detection and Assessment System (ICDAS) scores 4 or at least 1 carious lesion corresponding to ICDAS scores 5 and 6.\n\nExclusion Criteria:\n\n1. Children with systemic diseases such as immunodeficiency, cardiovascular disease, or bleeding disorders.\n2. Children are allergic to nickel and resin.\n3. Children unable to return for recall visits.\n4. Primary molar has signs of pulpal\u002Fperiapical diseases (irreversible pulpitis, pulp necrosis, loosening, fistula, or abscess).\n5. Children are undergoing orthodontic treatment with fixed or removable appliances.",{"count":303,"type":21},100,[24],"Stainless steel crowns have shown high success in restoring carious primary molars over a longer period of time than conventional restorations. This study aims to evaluate the treatment effectiveness of conventional SSCs restoration and Hall technique in treating carious primary molars",[27],[164,165,308],"Stainless steel crowns","2024-09-16",{"date":311,"type":36},"2024-09-19",{"date":313,"type":36},"2024-09-04",{"date":315,"type":21},"2026-05",{"name":317,"class":43},"Hue University of Medicine and Pharmacy",{"id":319,"slug":320,"hasResults":11,"nctId":321,"briefTitle":322,"officialTitle":323,"acronym":4,"eligibilityCriteria":324,"healthyVolunteers":52,"sex":16,"minAge":325,"maxAge":326,"enrollmentInfo":327,"targetDuration":4,"studyType":22,"phases":328,"briefSummary":329,"conditions":330,"keywords":332,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":334,"lastUpdatePostDateStruct":335,"startDateStruct":337,"completionDateStruct":339,"leadSponsor":341,"locationsCount":44},"100505388","evaluation-of-antimicrobial-post-operative-pain-of-cinnamon-extract-versus-sodium-hypochlorite-irrigant-following-pulpectomy-of-primary-teeth-100505388","NCT05860712","Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth","Evaluation Of Antimicrobial Potency Of A Novel Cinnamon Extract Irrigant Versus Sodium Hypochlorite Irrigant Following Pulpectomy Of Primary Teeth . (A Randomized Clinical Trial)","Inclusion Criteria:\n\n* Children:\n\n  1. Aged 4 to 8, in good general health, and medically free.\n  2. Cooperative patients who will comply to dental treatment .\n  3. Parents provided with written informed consent.\n  4. No previous history of antibiotics administration or last dose was taken from at least 2 weeks.\n* Teeth:\n\n  1. Carious primary molars with irreversible pulpitis.\n  2. Presence of localized swelling ,sinus and pain on percussion which indicate non vital pulp .\n  3. Presence of periapical and furcation radiolucency .\n  4. In periapical radiograph teeth have no more than 1\u002F3 of root resorption.\n\nExclusion Criteria:\n\n* Children:\n\n  1. Children with medical, physical, or mental conditions.\n  2. Severly Uncooperative children .\n* Teeth:\n\n  1. Primary molars with any congenital anomalies.\n  2. Teeth with un-restorable crowns .\n  3. Root resorbtion more than half of the root.\n\n     \\-","4 Years","8 Years",{"count":56,"type":21},[24],"The aim of the study is to evaluate effectiveness of cinnamon extract versus sodium hypochlorite as root canal irrigant for in pulpectomy of primary teeth in reduction of bacterial count .",[331,27],"Irreversible Pulpitis",[333],"antimicrobial and post operative pain evaluation","2024-08-20",{"date":336,"type":36},"2024-08-22",{"date":338,"type":36},"2024-01-20",{"date":340,"type":21},"2024-11-22",{"name":199,"class":43},{"id":343,"slug":344,"hasResults":11,"nctId":345,"briefTitle":346,"officialTitle":347,"acronym":4,"eligibilityCriteria":348,"healthyVolunteers":52,"sex":16,"minAge":232,"maxAge":349,"enrollmentInfo":350,"targetDuration":352,"studyType":100,"phases":4,"briefSummary":353,"conditions":354,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":356,"lastUpdatePostDateStruct":357,"startDateStruct":359,"completionDateStruct":361,"leadSponsor":362,"locationsCount":44},"100544161","caries-prevalence-experience-and-risk-related-factors-among-early-middle-aged-patients-attending-cairo-university-100544161","NCT06365281","Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University","Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Faculty of Dentistry, Cairo University","Inclusion Criteria:\n\n1. Patients whose age between 35 to 44 years old.\n2. Patient consulting in the outpatient clinic\n3. Provide informed consent\n4. Co-operative patients approving to participate in the trial.\n5. Males \\& Females\n6. Egyptian\n\nExclusion Criteria:\n\n1. Patients under or over this age group\n2. Lack of compliance\n3. Disabilities","44 Years",{"count":351,"type":21},350,"1 Day","Dental caries, a widespread oral health issue, results from a complex interplay of factors including behavior, hygiene, diet, and socio-demographic aspects. While preventive measures are available, it remains prevalent globally, affecting numerous teeth per individual. Improved oral hygiene practices and increased awareness have led to a reduction in caries prevalence. However, rising sugar consumption exceeds dietary guidelines, contributing to the problem. Despite limited epidemiological studies in Egypt, addressing individual-level factors is crucial. Surveillance of oral health in the early middle age group is standard, allowing decision-makers to assess the impact of caries and oral health care provision. Stratifying data by age, geography, and gender aids in understanding prevalence and planning effective prevention strategies. Overall, promoting awareness of dietary habits and preventive practices is vital for improving oral health outcome So, The purpose of this study is to assess the prevalence of dental caries among early middle age patients attending dental hospital in Faculty of Dentistry, Cairo university and to analyze the related risk factors utilizing WHO Oral Health Questionnaire for Adults.",[355,27],"Dental Caries","2024-08-19",{"date":358,"type":36},"2024-08-21",{"date":360,"type":36},"2024-07-20",{"date":222,"type":21},{"name":199,"class":43},{"id":364,"slug":365,"hasResults":11,"nctId":366,"briefTitle":367,"officialTitle":368,"acronym":4,"eligibilityCriteria":369,"healthyVolunteers":52,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":370,"targetDuration":4,"studyType":100,"phases":4,"briefSummary":372,"conditions":373,"keywords":376,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":380,"lastUpdatePostDateStruct":381,"startDateStruct":383,"completionDateStruct":385,"leadSponsor":386,"locationsCount":4},"100500127","kap-of-dental-practitioners-regarding-cra-100500127","NCT05792215","KAP of Dental Practitioners Regarding CRA","Dental Practitioners' Knowledge, Attitude, and Practice (KAP) in Cairo and Riyadh Regarding Caries Risk Assessment and Management: A Cross-Sectional Study","Inclusion Criteria:\n\n* Licensed Egyptian and Saudi general dentists.\n\nExclusion Criteria:\n\n* Undergraduate dental students\n* Dental specialists\n* Dentists who refused to participate",{"count":371,"type":21},174,"The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.",[27,374,375],"Tooth Decay","Tooth Diseases",[377,378,379],"Caries Risk Assessment","Caries Prevention","General Practitioners","2024-08-01",{"date":382,"type":36},"2024-08-02",{"date":384,"type":21},"2024-09-01",{"date":262,"type":21},{"name":199,"class":43},{"id":388,"slug":389,"hasResults":11,"nctId":390,"briefTitle":391,"officialTitle":392,"acronym":4,"eligibilityCriteria":393,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":394,"enrollmentInfo":395,"targetDuration":4,"studyType":100,"phases":4,"briefSummary":397,"conditions":398,"keywords":399,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":404,"lastUpdatePostDateStruct":405,"startDateStruct":407,"completionDateStruct":409,"leadSponsor":411,"locationsCount":4},"100550577","accuracy-of-iccms-versus-simplified-cariogram-100550577","NCT06448884","Accuracy of ICCMS Versus Simplified Cariogram","Accuracy of the Caries Risk Assessment of International Caries Classification and Management System (ICCMS) Versus Simplified Cariogram in the Egyptian Young Adult Population","Inclusion Criteria:\n\n* Age ranging from 18 to 29 years.\n* The presence of dental caries or restoration.\n\nExclusion Criteria:\n\n* Patients with no caries.\n* Patients diagnosed of psychiatric disease.\n* Patients not willing to be part of the study or ones who refuse to sign the informed consent.","29 Years",{"count":396,"type":21},323,"The study aims to compare the validity of the caries risk assessment regarding the comprehensive ICCMs Caries risk and likelihood matrix versus the simplified Cariogram aiming to see if there is a significant difference in the caries risk levels between both models.",[27],[400,401,402,403],"Risk","Validity","Cariogram","ICCMS","2024-06-03",{"date":406,"type":36},"2024-06-07",{"date":408,"type":21},"2024-06-15",{"date":410,"type":21},"2025-04",{"name":412,"class":43},"Kirolos Hisham Nadi Sedek",{"id":414,"slug":415,"hasResults":11,"nctId":416,"briefTitle":417,"officialTitle":418,"acronym":4,"eligibilityCriteria":419,"healthyVolunteers":52,"sex":16,"minAge":53,"maxAge":420,"enrollmentInfo":421,"targetDuration":4,"studyType":22,"phases":423,"briefSummary":424,"conditions":425,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":426,"lastUpdatePostDateStruct":427,"startDateStruct":429,"completionDateStruct":431,"leadSponsor":433,"locationsCount":44},"100360170","cardec-pel-comparison-of-two-methods-of-caries-risk-assessment-in-children-100360170","NCT03969628","CARDEC-PEL: Comparison of Two Methods of Caries Risk Assessment in Children","CARies DEtection in Children-Pelotas (CARDEC-PEL): Comparison of Two Methods of Caries Risk Assessment in Children","Inclusion Criteria:\n\n* Individuals aged 7 years months to 11 years;\n* Children seeking dental treatment at the Pediatric dentistry university clinic in Pelotas (UFPel)\n\nExclusion Criteria:\n\n* Medical and\u002For behavioral conditions that requires special considerations regarding management\u002Ftreatment of the child","11 Years",{"count":422,"type":21},250,[24],"The aim of the study was to compare dental caries treatment and follow-up based on an elaborate and individualized assessment of caries risk in children, to a simpler risk assessment strategy by means of a double-blind randomized clinical trial of two years monitoring. Participants will be children from 7 to 11 years old, who pass through the screening of the Children's Clinic of the Faculty of Dentistry of the Federal University of Pelotas and fulfill the inclusion criteria. A randomized, stratified sample of approximately 250 children will be included in the study, one group will be composed of children undergoing dental caries-related treatment and maintenance, guided by an individualized and multivariate risk assessment, and another group of children treated based on dental caries experience alone in the deciduous and \u002F or permanent dentition. Recruitment will begin at the beginning of 2019, and participants will be followed up for 24 months. Parents will respond to an anamnesis, 24-hour dietary recall, food frequency questionnaire, and oral and general health-related quality of life questionnaire, children will undergo a clinical examination to assess caries, according to the International Caries Detection and Assessment System (ICDAS) in its simplified form and evaluation of caries activity. Dental treatments and return intervals will be designated according to the individual risk of the patient detected in the initial approach according to the group. The study evaluations consist of baseline, 12 months and 24 months, data will be transferred to spreadsheets after the different phases of the study. Primary outcomes (number of dental surfaces requiring operative intervention) and secondary outcomes will be analyzed by Student's t test, quality of life and quality of life related to oral health, will be assessed at the beginning of the study and at the end of treatment, and compared between the groups.",[27],"2023-04-24",{"date":428,"type":36},"2023-04-25",{"date":430,"type":36},"2019-06-01",{"date":432,"type":21},"2028-06-01",{"name":434,"class":43},"Federal University of Pelotas"]