[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"carious-molars\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:carious-molars":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100579172","hybrid-resin-composite-vs-hybrid-ceramic-onlays-for-restoring-carious-molars-100579172",false,"NCT06820840","Hybrid Resin Composite vs. Hybrid Ceramic Onlays for Restoring Carious Molars","Comparative Clinical Performance of Hybrid Resin Composite vs. Hybrid Ceramic Onlays in the Restoration of Carious Molars: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Able to tolerate necessary restorative procedures\n* Willing to sign the informed consent\n* Accepts the follow-up period\n\nExclusion Criteria:\n\n* ICDAS 4\u002F5 cavities in first and second permanent molars\n* Onlay cavities with at least one cusp coverage\n* Patients with acceptable oral hygiene","ALL","18 Years","50 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to compare the clinical performance of hybrid resin composite and hybrid ceramic onlays in restoring carious molars. It will also evaluate the wear resistance of both materials. The main questions it aims to answer are:\n\n* Does the hybrid resin composite or hybrid ceramic onlay perform better in clinical settings over time?\n* How much wear occurs in each type of onlay over 18 months?\n\nResearchers will compare SHOFU Ceramage (hybrid resin composite) to SHOFU Block HC Hard(hybrid ceramic) to see which material performs better in restoring molars with extensive caries.\n\nParticipants will:\n\n* Receive either a hybrid resin composite or hybrid ceramic onlay for their molar cavities.\n* Visit the clinic for checkups at baseline, 6 months, 12 months, and 18 months.\n* Undergo visual assessments of their restorations and quantitative wear analysis during follow-ups.",[27],"Carious Molars",[29,30,31,32,33,34,35,36,37,38],"Onlay","Onlays","Hybrid resin composite","Hybrid ceramic","SHOFU","Ceramage","S-PRG","SPRG","Vital molars","Block HC Hard","RECRUITING","2026-03-31",{"date":42,"type":43},"2026-04-06","ACTUAL",{"date":45,"type":43},"2025-07-22",{"date":47,"type":21},"2028-12",{"name":49,"class":50},"Peter Medhat Youssef Gerges","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":64,"conditions":65,"keywords":75,"overallStatus":83,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":51},"100584440","phase-2-clinical-and-radiographic-evaluation-of-indirect-pulp-capping-using-platelet-rich-fibrin-versus-mineral-trioxide-aggregate-in-deep-carious-molars-a-randomized-controlled-trial-100584440","NCT06889363","Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial","Inclusion Criteria:\n\n* o Patients with asymptomatic deep carious molars.\n\n  * Patients with clinically and radiographically confirmed deep carious lesions that do not exhibit spontaneous pain.\n  * Permanent molars only.\n  * Teeth with intact or minimally restored occlusal surfaces (i.e., no extensive restorations or fractures).\n  * No history of previous endodontic treatment or direct pulp capping on the study tooth.\n  * No signs of periapical pathology based on radiographic evaluation.\n  * Patients willing to participate and follow up for 12 months.\n  * Patients who agree to return for scheduled follow-ups at 3, 6, and 12 months.\n\nExclusion Criteria:\n\n* o Patients with systemic conditions affecting bone or tissue healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppressed conditions).\n\n  * Pregnant or lactating women (if applicable to your study).\n  * Teeth with pulp exposure or necrotic pulp.\n  * Presence of symptomatic irreversible pulpitis (e.g., spontaneous pain, lingering pain).\n  * Periapical pathology or internal\u002Fexternal resorption detected radiographically.\n  * Severely broken down or non-restorable teeth.\n  * Calcified root canals or excessive sclerosis that could affect pulp testing reliability.\n  * Any pre-existing root canal treatment on the selected tooth.\n  * Patients who have undergone recent fluoride treatment, pulpotomy, or other pulp therapies in the past 6 months.\n  * Patients using medications affecting bone and tissue regeneration (e.g., bisphosphonates, corticosteroids).\n  * Patients unwilling or unable to commit to the 12-month follow-up schedule.\n  * Patients with poor oral hygiene or high caries risk that could compromise treatment outcomes.","20 Years","40 Years",{"count":61,"type":21},50,[63],"PHASE2","The aim of this study is the clinical and radiographic evaluation of (Platelet-Rich Fibrin (PRF) versus Mineral Trioxide Aggregate (MTA) in indirect pulp capping when used with deep carious molars over 1 year follow up.",[66,67,68,69,70,71,72,73,74,27],"Dental Caries","Pulp Caping","Indirect Pulp Treatment","Indirect Pulp Cap","Indirect Pulp Capping","Indirect Pulp Therapy","Deep Carious Lesion","Deep Carious Lesions","Molar Caries",[76,77,78,79,80,81,82],"Molar caries","MTA","PRF","Indirect pulp capping","Deep carious lesion","carious molars","platelet rich fibrin","NOT_YET_RECRUITING","2025-03-17",{"date":86,"type":43},"2025-03-21",{"date":88,"type":21},"2025-06",{"date":90,"type":21},"2026-09",{"name":92,"class":50},"Cairo University"]