[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"carnitine-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:carnitine-deficiency":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100608450","early-phase-1-oral-carnitine-in-heart-failure-patients-100608450",false,"NCT07201714","Oral Carnitine in Heart Failure Patients","Oral L-Carnitine Supplementation in Cardiorenal Heart Failure Patients","Inclusion Criteria:\n\n* Clinical-pathological diagnosis of heart failure with some degree of cardiorenal syndrome\n* Stage 1, 2, 3a, 3b, or 4 chronic kidney disease\n* Age ≥ 18 years\n* Able to speak and read English\n* Willing and able to provide consent\n\nExclusion Criteria:\n\n* Estimated GFR \\\u003C15 mL\u002Fmin\u002F1.73m2 or Stage 5 chronic kidney disease\n* Currently undergoing renal replacement therapy of any kind\n* Pregnant, breastfeeding or intending pregnancy\n* History of seizures of any type\n* Known allergy to levocarnitine, magnesium stearate, microcrystalline cellulose or povidone\n* Unable to provide consent","ALL","18 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"EARLY_PHASE1","Heart failure is a condition in which the heart is unable to pump blood effectively, leading to symptoms like being more tired, shortness of breath, and swelling in the body. Carnitine is a naturally occurring substance in the body that plays a role in turning fat into energy. This study will determine whether oral L-Carnitine supplementation can improve symptoms, enhance heart function and possibly improve the quality of life in individuals with heart failure.",[26,27],"Heart Failure","Carnitine Deficiency","RECRUITING","2026-04-15",{"date":31,"type":32},"2026-04-20","ACTUAL",{"date":34,"type":32},"2025-11-12",{"date":36,"type":20},"2026-12-31",{"name":38,"class":39},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER"]