[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"carpometacarpal-cmc-joint-arthritis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:carpometacarpal-cmc-joint-arthritis":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":5},"100636735","surgery-for-thumb-base-osteoarthritis-joint-replacement-vs-trapeziectomy-100636735",false,"NCT07569549","Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy","BASTION - BASe of Thumb Osteoarthritis Management Non-inferiority Trial: Surgical Treatment of First Carpometacarpal Joint Osteoarthritis: A Comparison Between Joint Replacement and Trapeziectomy","BASTION","Inclusion Criteria:\n\n* Age 40-80 years at inclusion\n* CMC-joint osteoarthritis grade 1-3 (Eaton-Littler classification)\n* Rest pain or pain reducing hand function with indication for surgery\n* Insufficient relief from non-operative treatment for ≥3 months (orthosis, OTC analgesics, cortisone injection)\n* Eligible for both prosthesis and trapezectomy per including surgeon\n* Non-smoker or complete smoking cessation ≥6 weeks prior to surgery\n\nExclusion Criteria:\n\n* Previous surgery to thumb base or STT-joint\n* Ongoing chronic pain condition\n* Dementia or cognitive impairment\n* Trapezium height \\\u003C7 mm on plain radiograph\n* Active smoker\n* Osteoarthritis grade 4 (Eaton-Littler)","ALL","40 Years","80 Years",{"count":21,"type":22},84,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint osteoarthritis.\n\nThe main questions it aims to answer are:\n\nDoes surgery with total joint arthroplasty provide better power grip and pinch grip strength compared to traditional surgery?\n\nWhat is the long-term risk of complications for both methods?\n\nWhich method is more cost-effective for the healthcare system?\n\nResearchers will compare total joint arthroplasty (TOUCH) to trapezectomy (a procedure where a bone in the thumb base is removed) to see which method provides the best results for the patient.\n\nParticipants will:\n\nBe randomized to undergo either an operation with total joint arthroplasty or a trapezectomy.\n\nUndergo an initial evaluation and a health economic cost analysis after one year.\n\nAttend follow-up checkups at 2, 5, and 10 years post-surgery to evaluate long-term function and the durability of the prosthesis.",[28,29,30,31],"Thumb Osteoarthritis","Thumb Carpometacarpal Joint Osteoarthritis","Carpometacarpal (CMC) Joint Arthritis","Basal Thumb Osteoartrithis",[33,34,35,36,37,38,39,28,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61],"Thumb base arthroplasty","CMC joint","prosthesis","hand surgery","First Carpometacarpal Joint","Trapeziometacarpal Joint","Rhizarthrosis","Dual Mobility Prosthesis","Total Joint Replacement","Total Joint Arthroplasty","Ligament Reconstruction","Surgical Reconstruction","Randomized Controlled Trial (RCT)","Prospective Studies","Comparative Study","Prospective Study","Cost-Effectiveness Analysis","Cost-Benefit Analysis","Health Economics","Patient Reported Outcome Measures (PROMs)","Quality of Life (QoL)","Health-Related Quality of Life (HRQoL)","Return to Work","Grip Strength","Pinch Strength","QuickDASH","EQ-5D","Michigan Hand Outcomes Questionnaire (MHQ","Trapeziectomy","RECRUITING","2026-06-22",{"date":65,"type":66},"2026-06-25","ACTUAL",{"date":68,"type":22},"2026-07-01",{"date":70,"type":22},"2038-03",{"name":72,"class":73},"Uppsala University","OTHER",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":82,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":23,"phases":85,"briefSummary":86,"conditions":87,"keywords":88,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":100},"100583440","woodcasting-versus-thermoplast-splint-in-cmc-arthroplasty-100583440","NCT06876350","Woodcasting Versus Thermoplast Splint in CMC Arthroplasty","Patient Satisfaction for Post-Operative Carpometacarpal Arthroplasty: Wood Casting Versus Thermoplastic Splint","Woodcast","Inclusion Criteria:\n\n* Patients over the age of 18 years old.\n* Intact Medical Decision Making\n* Eligible for Surgical Intervention\n* Willing to comply with all aspects of the treatment and evaluation schedule over 6 weeks\n\nExclusion Criteria:\n\n* Pregnant Women\n* Deemed Unsuitable by Principal Investigator","18 Years",{"count":84,"type":22},26,[25],"This study is a prospective, randomized, nonblinded trial to evaluate patient preference in splints after having a carpometacarpal arthroplasty.",[30],[89,90],"Randomized","Hand and Upper Extremity","2025-03-13",{"date":93,"type":66},"2025-03-17",{"date":95,"type":66},"2024-10-03",{"date":97,"type":22},"2025-06-30",{"name":99,"class":73},"Foundation for Orthopaedic Research and Education",1]