[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"carrier-state\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:carrier-state":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,62,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100579962","aquagenic-wrinkling-prediction-100579962",false,"NCT06831110","Aquagenic Wrinkling Prediction","Using Aquagenic Wrinkling to Predict CF Carrier State","Inclusion Criteria:\n\n* Interested in participating in other CF Carrier-related research studies.\n\nExclusion Criteria:\n\n* CF patient status\n* Unable to speak English\n* Unable to provide written informed consent\n* Prisoner status\n* An open wound on either hand\n* A tattoo on either hand\n* Missing any portion of either hand\n* Diagnosis of Diabetes\n* Diagnosis of Hyperhidrosis\n* Diagnosis of Raynaud's Disease\n* Diagnosis of Atopic Dermatitis\n* Regularly taking ACE inhibitors or angiotensin receptor blockers",true,"ALL","18 Years","24 Years",{"count":21,"type":22},2000,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status.\n\nParticipants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.",[26,27],"Aquagenic Wrinkling of Palms","Carrier State","RECRUITING","2026-06-02",{"date":31,"type":32},"2026-06-04","ACTUAL",{"date":34,"type":32},"2025-03-06",{"date":36,"type":22},"2026-12",{"name":38,"class":39},"University of Iowa","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":61,"locationsCount":40},"100581203","genetic-risk-factor-for-heat-stroke-100581203","NCT06847256","Genetic Risk Factor for Heat Stroke","Exploring a Common Genetic Risk Factor for Heat Stroke and Dehydration","Inclusion Criteria:\n\n* Previously genotyped as a CF carrier or control\n* Comfortable speaking\u002Freading English\n\nExclusion Criteria:\n\n* Previously genotyped as a CF patient\n* Diagnosis of Type 1 or Type 2 diabetes\n* History of heart attack, stroke, heart failure, or atherosclerosis\n* Currently pregnant\n* Currently taking beta blockers or diuretics\n* Prisoner status\n* Unable to provide own written informed consent","60 Years",{"count":50,"type":22},200,"The goal of this observational study is to examine the effect of the Cystic Fibrosis (CF) Carrier state on the risk for dehydration and other CF-specific fluid-and-electrolyte disorders in male and female adults.\n\nThe primary aim of the study is to estimate the risk of electrolyte disorders attributable to the CF carrier state in a genotyped cohort.\n\nThis will be accomplished with two smaller projects- Aim 1 and Aim 2.\n\nAim 1 will consist of 100 CF Carriers and 100 age- and sex-matched controls. Participants in this aim will be asked to complete a Participant Info and Temperature Survey consisting of questions about race, ethnicity, medical history, and how they experience heat.\n\nAim 2 will consist of a subset of 25 CF Carriers and 25 age- and sex-matched controls from Aim 1. Participants in this aim will be scheduled for a visit to complete a heat challenge. At this visit, they will also complete the Participant Info and Temperature Survey. They will also sit in a sauna at 62 - 63 degrees Celsius for 45 minutes.",[27,53,54],"Heat Stroke","Dehydration","2026-04-21",{"date":57,"type":32},"2026-04-27",{"date":59,"type":32},"2025-11-19",{"date":36,"type":22},{"name":38,"class":39},{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":4,"eligibilityCriteria":67,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":68,"enrollmentInfo":69,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":71,"conditions":72,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":40},"100475706","the-effects-of-the-cf-carrier-state-on-the-kidneys-and-pancreas-100475706","NCT05474417","The Effects of the CF Carrier State on the Kidneys and Pancreas","CF Carrier Inclusion Criteria:\n\n* A CF Carrier identified via genetic testing\n\nControl Inclusion Criteria:\n\n* No previous CF carrier test results\n\nExclusion Criteria:\n\n* CF patient status\n* Unable to speak English\n* Currently pregnant\n* Unable to provide written informed consent\n* Prisoner status\n* Currently taking any medications for the treatment of diabetes","100 Years",{"count":70,"type":22},1250,"The overarching hypothesis is that CF carriers are at increased risk for developing most of the extrapulmonary conditions associated with CF compared to the general population. Specifically, it is hypothesized that this pilot data will detect subclinical evidence of pancreatic and kidney disorders among CF carriers. This will be determined by bringing CF carriers and controls to the CRU for one visit where they will answer survey questions and undergo laboratory testing. Additionally, they will collect urine and stool samples at home that will be sent to outside laboratories for testing.",[27,73,74],"Pancreatic Disease","Kidney Diseases","2026-01-05",{"date":77,"type":32},"2026-01-07",{"date":79,"type":32},"2021-12-20",{"date":81,"type":22},"2026-07",{"name":83,"class":39},"Philip Polgreen",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":68,"enrollmentInfo":91,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":96,"startDateStruct":97,"completionDateStruct":98,"leadSponsor":99,"locationsCount":40},"100475707","estimating-risk-of-respiratory-infections-attributable-to-cftr-heterozygosity-100475707","NCT05474430","Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity","Estimating the Risk for and Severity of Respiratory Infections Attributable to CFTR Heterozygosity","CF Carrier Inclusion Criteria:\n\n* Previously tested and shown to be a CF carrier\n* English-speaking\n\nControl Group Inclusion Criteria:\n\n* Previously tested and shown to not be a CF carrier or CF patient\n* English-speaking\n\nExclusion Criteria:\n\n* Currently sick with a respiratory infection\n* Prisoner Status\n* Unable to provide own written, informed consent",{"count":92,"type":22},160,"A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays.\n\nAn individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube of blood to test fibroblast growth factor-19.\n\nThe participant will answer questions from the baseline survey and report their current medications interview-style with the research team member.",[27,95],"Respiratory Infections",{"date":77,"type":32},{"date":79,"type":32},{"date":81,"type":22},{"name":83,"class":39}]