[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cartilage-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cartilage-disease":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100534447","long-term-outcome-evaluation-of-patients-undergoing-autologous-chondrocyte-transplantation-delivered-on-biomaterial-100534447",false,"NCT06238947","Long-term Outcome Evaluation of Patients Undergoing Autologous Chondrocyte Transplantation Delivered on Biomaterial","LONG-TERM EVALUATION OF OUTCOMES OF PATIENTS UNDERGOING AUTOLOGOUS CHONDROCYTE TRANSPLANTATION DELIVERED ON BIOMATERIAL (HYALOGRAFT C) Prospective Observational Study","Inclusion Criteria:\n\n* Patients who underwent autologous chondrocyte transplantation surgery delivered on biomaterial (Hyalograft C) from 1999 to 2006 at the Rizzoli Orthopaedic Institute who met the following criteria at the time of surgery:\n* Full-thickness chondral defects (Outerbridge grade III - IV) and osteochondral defects at the femoral condyles, trochlea, patella and tibial plateau.\n* Patients aged between 14 and 60 years at the time of surgery.\n* Male and female sex.\n\nExclusion Criteria:\n\n* Patients no longer available","ALL","14 Years","60 Years",{"count":20,"type":21},200,"ESTIMATED","OBSERVATIONAL","Chondro-Long study is prospective observational study for a long-term clinical evaluation (follow-up up to 25 years) in patients treated with autologous chondrocyte transplantation delivered on biomaterial for full-thickness chondral defects (Outerbridge grade III - IV) at the level of femoral condyles, trochlea, patella and tibial plateau.\n\nThe aim of the study is to collect long-term clinical data from the case series of patients surgically treated from 1999 to 2006 with autologous chondrocyte transplantation delivered on biomaterial for full-thickness chondral defects (Outerbridge grade III - IV) or osteochondral defects at the level of femoral condyles, trochlea, patella, and tibial plateau. The objective of the study is to demonstrate the efficacy of this long-term cartilage regeneration technique (follow-up up to 25 years) in improving patient symptomatology and functional capacity",[25,26],"Cartilage Injury","Cartilage Disease",[28,29],"autologous chondrocyte transplantation","osteochondral defects","NOT_YET_RECRUITING","2026-06-30",{"date":33,"type":34},"2026-07-01","ACTUAL",{"date":36,"type":21},"2026-09",{"date":38,"type":21},"2027-02",{"name":40,"class":41},"Istituto Ortopedico Rizzoli","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100556472","early-motion-total-ankle-artroplasty-100556472","NCT06525545","Early MOtion Total Ankle Artroplasty","Comparison of Clinical and Radiological Results of Patients Undergoing Total Ankle Arthroplasty and Treated With Early Mobilization or With Cast Immobilization","EMOTAA","Inclusion Criteria:\n\n* Adult patients (aged between 18 and 80).\n* Male or female patients;\n* Signature of the informed consent for participation in the study;\n* Patients prepared and motivated to comply with the scheduled follow-up visits and the completion of the study questionnaires\n\nExclusion Criteria:\n\n* main diagnosis other than osteoarthritis, history of ankle infection\n* need to carry out surgical interventions associated with total prosthesis ankle (e.g., calcaneal osteotomy, knee lowering osteotomy).\n\nfirst metatarsal bone, supramalleolar osteotomy, etc.)\n\n* intraoperative complications (for example a malleolar fracture) which require a different post-operative protocol\n* peripheral vascular disease\n* marked osteoporosis of the ankle and foot\n* osteonecrosis of the talus\n* neurological disorders affecting the lower limb inability to understand study information or respond to questionnaires due to cognitive or linguistic deficits\n* patients who are pregnant or breastfeeding","18 Years","80 Years",{"count":53,"type":21},72,"INTERVENTIONAL",[56],"NA","Evaluate the clinical and radiographic results of patients undergoing total ankle arthroplasty and treated in the post-operative period in a randomized manner with early mobilization of the ankle joint or with cast immobilization for 3 weeks",[59,60,26,61],"Ankle Osteoarthritis","Ankle - Recurrent Dislocation","Ankle Arthropathy","RECRUITING","2024-07-31",{"date":65,"type":34},"2024-08-02",{"date":67,"type":34},"2023-10-31",{"date":69,"type":21},"2027-10-31",{"name":40,"class":41},1]